diethyl amine
2,2'-diethylamine
Identification
| Name | diethyl amine |
| CAS Number | 109-89-7 |
| EINECS | 203-716-3 |
| FDA UNII | B035PIS86W |
| Molecular Formula | C4 H11 N |
| Molecular Weight | 73.13867000 |
| MDL Number | MFCD00009032 |
| Nikkaji Number | J807I |
| Beilstein | 0605268 |
| CoE Number | 10470 |
| XlogP3 | 0.60 (est) |
Regulatory
| FDA Mainterm (IAUFC) | 109-89-7 ; DIETHYLAMINE |
| FDA Regulation | FDA PART 175 -- INDIRECT FOOD ADDITIVES: ADHESIVES AND COMPONENTS OF COATINGS |
Physical Properties
| Appearance | colorless clear liquid (est) |
| Assay | 98.00 to 100.00 |
| Food Chemicals Codex Listed | No |
| Specific Gravity | 0.70400 to 0.70800 @ 20.00 °C. |
| Pounds per Gallon - (est). | 5.865 to 5.898 |
| Refractive Index | 1.38300 to 1.38700 @ 20.00 °C. |
| Melting Point | -5.00 to -4.50 °C. @ 760.00 mm Hg |
| Boiling Point | 55.00 to 58.00 °C. @ 760.00 mm Hg |
| Vapor Pressure | 237.000000 mmHg @ 25.00 °C. |
| Vapor Density | 2.5 ( Air = 1 ) |
| Flash Point | -18.00 °F. TCC ( -27.78 °C. ) |
| logP (o/w) | 0.580 |
| Soluble in | water, 4.369e+005 mg/L @ 25 °C (est) |
Cosmetic Information
| CosIng | cosmetic data |
| Cosmetic Uses | buffering agents |
Organoleptic Properties
| Odor Description | at 0.10 % in dipropylene glycol. |
Safety Information
| Preferred SDS | View |
| European information | Most important hazard(s): |
| Oral/Parenteral Toxicity | oral-rat LD50 540 mg/kg |
| Dermal Toxicity | skin-rabbit LD50 820 ul/kg |
| Inhalation Toxicity | inhalation-rat LC50 4000 ppm/4H |
GHS Classification
['GHS Classification in accordance with 29 CFR 1910 (OSHA HCS)', 'GHS Label elements, including precautionary statements']
Safety in Use
| Category | indirect food additives: adhesives and components of coatings |
| Recommendation for diethyl amine usage levels up to | not for fragrance use. |
| Recommendation for diethyl amine flavor usage levels up to | not for flavor use. |
Penta International Corporation
Chemistry innovation
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Potential Uses
Natural Occurrence
Synonyms
diethylamine
2,2'-
diethylamine
diethylamine [UN1154] [Flammable liquid]
N-
ethylethanamine
PubMed:
Systematic analysis of the ability of Nitric Oxide donors to dislodge biofilms formed by Salmonella enterica and Escherichia coli O157:H7.
PubMed:
[Determination of enantiomeric impurity of timolol maleate in bulk substances and eye drops].
PubMed:
Gas chromatography-mass spectrometry assessment of amines in Port wine and grape juice after fast chloroformate extraction/derivatization.
PubMed:
Microwave-assisted extraction and determination of cyanuric acid residue in pet food samples by liquid chromatography-tandem mass spectrometry.
PubMed:
Determination of melamine and its analogues in egg by gas chromatography-tandem mass spectrometry using an isotope dilution technique.
PubMed:
Chiral stationary phases for separation of intermedine and lycopsamine enantiomers from Symphytum uplandicum.
PubMed:
Determination of sulfonamides in swine muscle after salting-out assisted liquid extraction with acetonitrile coupled with back-extraction by a water/acetonitrile/dichloromethane ternary component system prior to high-performance liquid chromatography.
PubMed:
[Determination of melamine and cyanuric acid in milk by gas chromatography-mass spectrometry].
PubMed:
Simultaneous determination of melamine, ammelide, ammeline, and cyanuric acid in milk and milk products by gas chromatography-tandem mass spectrometry.
PubMed:
Simultaneous determination of azaperone and azaperol in animal tissues by HPLC with confirmation by electrospray ionization mass spectrometry.
PubMed:
Diagnostic determination of melamine and related compounds in kidney tissue by liquid chromatography/tandem mass spectrometry.
PubMed:
Selective separation of the major whey proteins using ion exchange membranes.
PubMed:
Alkynyl polysaccharides: synthesis of propargyl potato starch followed by subsequent derivatizations.
PubMed:
A simple and rapid method for simultaneous determination of benzoic and sorbic acids in food using in-tube solid-phase microextraction coupled with high-performance liquid chromatography.
PubMed:
HPLC determination and steady-state bioavailability study of levodropropizine sustained-release tablets in dogs.
PubMed:
Synthesis of diethylamine-functionalized soybean oil.
PubMed:
Mammary blood flow does not limit milk yield in lactating goats.
PubMed:
Novel short chain chloroquine analogues retain activity against chloroquine resistant K1 Plasmodium falciparum.
PubMed:
Biological action of nitric oxide donor compounds on platelets from patients with sickle cell disease.
PubMed:
The analysis of beta-agonists by packed-column supercritical fluid chromatography with ultra-violet and atmospheric pressure chemical ionisation mass spectrometric detection.
PubMed:
Dietary secondary amines and liver hepatoma in Port Harcourt, Nigeria.
PubMed:
Local secretion of nitric oxide and the control of mammary blood flow.
PubMed:
Effects of food, ceruletide and ranitidine on the pharmacokinetics of the oral cephalosporin S-1108 in humans.
PubMed:
Increased exposure to dietary amines and nitrate in a population at high risk of oesophageal and gastric cancer in Kashmir (India).
PubMed:
Modulation of mycotoxin and nitrosamine carcinogenesis by indole-3-carbinol: quantitative analysis of inhibition versus promotion.
PubMed:
Determination of aliphatic amines in air by on-line solid-phase derivatization with HPLC-UV/FL.
PubMed:
[The effect of lysine-enriched bread on the formation of N-nitrosamines from their precursors in the stomach of dogs].
PubMed:
Ion-pair reverse-phase liquid chromatographic determination of amprolium in complete feeds and premixes.
PubMed:
Possible underestimation of nitrosatable amine levels in artificial saliva extracts of children's rubber pacifiers and baby-bottle teats.
PubMed:
The effect of food and time of administration on the absorption of diethylamine chromocarbe.
PubMed:
Abundance of dimethylamine in seafoods: possible implications in the incidence of human cancer.
PubMed:
Mutagenicity of pyrolysates from guanidine, ureide, secondary amines and polyamines found by the Salmonella/mammalian-microsome test.
PubMed:
Failure to induce tumours in guinea-pigs after concurrent administration of nitrite and diethylamine.