Identification

Namedimethoxymethane
CAS Number109-87-5
EINECS203-714-2
FDA UNII7H1M4G2NUE
Molecular FormulaC3 H8 O2
Molecular Weight76.09516000
MDL NumberMFCD00008495
Nikkaji NumberJ3.250F
Beilstein1697025
CoE Number10031
XlogP30.20 (est)

Regulatory

DG SANTE Food Flavourings06.074 dimethoxymethane

Physical Properties

Appearance colorless clear liquid (est)
Assay 95.00 to 100.00
Water Content ~0.1%
Food Chemicals Codex Listed No
Specific Gravity 0.85500 to 0.86200 @ 25.00 °C.
Pounds per Gallon - (est). 7.114 to 7.173
Refractive Index 1.35000 to 1.35600 @ 20.00 °C.
Melting Point -105.00 °C. @ 760.00 mm Hg
Boiling Point 42.00 °C. @ 760.00 mm Hg
Vapor Pressure 398.000000 mmHg @ 25.00 °C.
Flash Point 1.00 °F. TCC ( -17.22 °C. )
Soluble in alcohol

Cosmetic Information

CosIngcosmetic data
Cosmetic Usessolvents

Organoleptic Properties

Odor Description chloroform

Safety Information

Preferred SDSView
European informationMost important hazard(s):
Oral/Parenteral Toxicityoral-rat LD50 [sex: F] 7950 mg/kg
Dermal Toxicityskin-rabbit LD > 16 mL/kg
Inhalation Toxicityinhalation-mouse LC50 57000 mg/m3/7H

GHS Classification

['GHS Classification in accordance with 29 CFR 1910 (OSHA HCS)', 'GHS Label elements, including precautionary statements']

Safety in Use

Categorysolvents
Recommendation for dimethoxymethane usage levels up tonot for fragrance use.
Maximised Survey-derived Daily Intakes (MSDI-EU)0.012 (μg/capita/day)
Modified Theoretical Added Maximum Daily Intake (mTAMDI)1600 (μg/person/day)
Threshold of Concern1800 (μg/person/day)
Structure ClassI
Dairy products, excluding products of category 02.0 (01.0)3.00000
Fats and oils, and fat emulsions (type water-in-oil) (02.0)2.00000
Edible ices, including sherbet and sorbet (03.0)3.00000
Processed fruit (04.1)2.00000
Processed vegetables (incl. mushrooms & fungi, roots & tubers, pulses and legumes), and nuts & seeds (04.2)-
Confectionery (05.0)4.00000
Chewing gum (05.3)-
Cereals and cereal products, incl. flours & starches from roots & tubers, pulses & legumes, excluding bakery (06.0)2.00000
Bakery wares (07.0)5.00000
Meat and meat products, including poultry and game (08.0)1.00000
Fish and fish products, including molluscs, crustaceans and echinoderms (MCE) (09.0)1.00000
Eggs and egg products (10.0)-
Sweeteners, including honey (11.0)-
Salts, spices, soups, sauces, salads, protein products, etc. (12.0)2.00000
Foodstuffs intended for particular nutritional uses (13.0)3.00000
Non-alcoholic ("soft") beverages, excl. dairy products (14.1)2.00000
Alcoholic beverages, incl. alcohol-free and low-alcoholic counterparts (14.2)4.00000
Ready-to-eat savouries (15.0)5.00000
Composite foods (e.g. casseroles, meat pies, mincemeat) - foods that could not be placed in categories 01.0 - 15.0 (16.0)2.00000

ECSA Chemicals

Human Chemistry

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Potential Uses

solvents

Natural Occurrence

cognac PMC

Synonyms

dimethoxymethane 1,1- dimethoxymethane dimethyl formal formaldehyde dimethyl acetal formaldehyde dimethyl ketal formaldehyde dimethylacetal methane, dimethoxy- bis( methoxy)methane methoxymethyl methyl ether methylal methylene dimethyl ether methylene glycol dimethylether bis( methyloxy)methane PubMed: Biofiltration of high formaldehyde loads with ozone additions in long-term operation. PubMed: Highly stable CO2/N2 and CO2/CH4 selectivity in hyper-cross-linked heterocyclic porous polymers. PubMed: Clostridium geopurificans strain MJ1 sp. nov., a strictly anaerobic bacterium that grows via fermentation and reduces the cyclic nitramine explosive hexahydro-1,3,5-trinitro-1,3,5-triazine (RDX). PubMed: [Study on occupational exposure limit of dimethoxymethane in workplace air]. PubMed: [Progress in research on toxicity of dimethoxymethane and its occupational exposure limit]. PubMed: [Determination of dimethoxymethane in air of workplace by gas chromatography]. PubMed: DFT investigations for the reaction mechanism of dimethyl carbonate synthesis on Pd(II)/β zeolites. PubMed: [Determination of methylal in the air of workplace with solvent desorption by gas chromatography]. PubMed: Dimethoxymethane-hydrogen chloride interaction: gas phase versus low-temperature behavior studied using matrix isolation infrared and density functional theory methods. PubMed: How the generalized anomeric effect influences the conformational preference. PubMed: Intermolecular acetaldehyde and dimethoxymethane formation mechanisms via ethenol and methoxymethylene precursors in reactions of atomic carbon with methanol: a computational study. PubMed: Mechanistic investigations on dimethyl carbonate formation by oxidative carbonylation of methanol over a CuY zeolite: an operando SSITKA/DRIFTS/MS study. PubMed: A Ferrier-type allylic rearrangement of 3'-deoxy-3',4'-didehydronucleosides mediated by DMF dimethyl acetal: direct access to 4'-alkoxy-2',3'-didehydro-2',3'-dideoxynucleosides. PubMed: Selective oxidation of methanol to dimethoxymethane over bifunctional VO(x)/TS-1 catalysts. PubMed: An easily accessible Re-based catalyst for the selective conversion of methanol: evidence for an unprecedented active site structure through combined operando techniques. PubMed: Influence of the solvent on the charge distribution of anomeric compounds. PubMed: A systematic study on the activation of simple polyethers by MoCl5 and WCl6. PubMed: Ligand close packing, molecular compactness, the methyl tilt, molecular conformations, and a new model for the anomeric effect. PubMed: Vapor-phase carbonylation of dimethoxymethane over H-Faujasite. PubMed: Preparation and characterization of mesoporous VO(x)-TiO2 complex oxides for the selective oxidation of methanol to dimethoxymethane. PubMed: Molecular dynamics simulation of interactions between a sodium dodecyl sulfate micelle and a poly(ethylene oxide) polymer. PubMed: Amorphous oxide as a novel efficient catalyst for direct selective oxidation of methanol to dimethoxymethane. PubMed: Imaging momentum orbital densities of conformationally versatile molecules: a benchmark theoretical study of the molecular and electronic structures of dimethoxymethane. PubMed: Selective oxidation of methanol to dimethoxymethane under mild conditions over V2O5/TiO2 with enhanced surface acidity. PubMed: Noncovalent interactions and internal dynamics in dimethoxymethane-water. PubMed: Atoms in molecules interpretation of the anomeric effect in the O--C--O unit. PubMed: Selective oxidation of methanol and ethanol on supported ruthenium oxide clusters at low temperatures. PubMed: Ultraviolet photolysis of CH2I2 in methanol: O-H insertion and HI elimination reactions to form a dimethoxymethane product. PubMed: The external-anomeric torsional effect. PubMed: Electrochemical oxidation of methanol using dppm-bridged Ru/Pd, Ru/Pt and Ru/Au catalysts. PubMed: Diastereo- and enantioselective dearomatization of rhenium-bound naphthalenes. PubMed: Matrix isolation infrared and ab initio study of the conformations of 2,2-dimethoxypropane. PubMed: Tandem 1,4-addition reactions with benzene and alkylated benzenes promoted by pentaammineosmium(II). PubMed: Volatile metabolites from microorganisms grown on humid building materials and synthetic media. PubMed: Conformations of dimethoxymethane: matrix isolation infrared and ab initio studies. PubMed: Metastable ion study of organosilicon compounds. Part XIII: dimethoxydimethylsilane, (CH(3))(2)Si(OCH(3))(2), and dimethoxymethylsilane, CH(3)SiH(OCH(3))(2). PubMed: Porphyrins with exocyclic rings. 16. Synthesis and spectroscopic characterization of fluoranthoporphyrins, a new class of highly conjugated porphyrin chromophores. PubMed: Unimolecular metastable decompositions of gem-dimethoxyalkanes (RR'C(OCH(3))(2)) upon electron impact. I. Dimethoxymethane and 1, 1-dimethoxyethane PubMed: [Gas chromatographic determination of methylal in atmospheric air]. PubMed: [Methylal: its metabolism and hygienic standardization in the air of work areas]. PubMed: Determination of phosphatidylglycerol in amniotic fluid by a simple one-dimensional thin-layer chromatography method. PubMed: Convenient synthesis of N-alkoxymethylbarbituric acids and N-alkoxymethylhydantoins. PubMed: A chemical assay method for the determination of aflatoxin residues in animal tissues. PubMed: The toxicity of methylal. PubMed: Anesthesia with methylal in dogs, mice and rats.