dimethyl (S)-(-)-malate

dimethyl L-(-)-malate

CAS: 617-55-0 C6 H10 O5 MW: 162.14170000

Identification

Namedimethyl (S)-(-)-malate
CAS Number617-55-0
FDA UNIISearch
Molecular FormulaC6 H10 O5
Molecular Weight162.14170000
MDL NumberMFCD00066215
Nikkaji NumberJ96.546D
Beilstein1724363

Regulatory

Physical Properties

Assay 95.00 to 100.00
Food Chemicals Codex Listed No
Specific Gravity 1.23200 to 1.23600 @ 20.00 °C.
Pounds per Gallon - (est). 10.263 to 10.297
Refractive Index 1.43800 to 1.44200 @ 20.00 °C.
Boiling Point 249.60 °C. @ 760.00 mm Hg (est)
Flash Point > 230.00 °F. TCC ( > 110.00 °C. )
logP (o/w) -0.830 (est)
Soluble in water, 1e+006 mg/L @ 25 °C (est)

No sensory data available

Safety Information

Preferred SDSView
Oral/Parenteral ToxicityNot determined
Dermal ToxicityNot determined
Inhalation ToxicityNot determined

GHS Classification

['GHS Classification in accordance with 29 CFR 1910 (OSHA HCS)', 'GHS Label elements, including precautionary statements']

Safety in Use

Categoryinformation only not used for fragrances or flavors
Recommendation for dimethyl (S)-(-)-malate usage levels up tonot for fragrance use.
Recommendation for dimethyl (S)-(-)-malate flavor usage levels up tonot for flavor use.

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Potential Uses

None Found

Natural Occurrence

not found in nature

Synonyms

dimethyl (2S)-2-hydroxybutanedioate dimethyl (S)-2-hydroxysuccinate dimethyl (S)-malate dimethyl L-(-)-malate L- malic acid dimethyl ester PubMed: [Chemical constituents from Ganoderma philippii]. PubMed: Mitochondrial biogenesis and energy production in differentiating murine stem cells: a functional metabolic study. PubMed: Inhibitors of ROS production by the ubiquinone-binding site of mitochondrial complex I identified by chemical screening. PubMed: Tumor cell death induced by the inhibition of mitochondrial electron transport: the effect of 3-hydroxybakuchiol. PubMed: Advances in mycobacterial isocitrate lyase targeting and inhibitors. PubMed: Tyrosine kinase receptor inhibitor-targeted combined chemotherapy for metastatic bladder cancer. PubMed: Supplement of TCA cycle intermediates protects against high glucose/palmitate-induced INS-1 beta cell death. PubMed: Structure of oxalacetate acetylhydrolase, a virulence factor of the chestnut blight fungus. PubMed: 6,8-Di-C-glycosyl flavonoids from Dendrobium huoshanense. PubMed: Role for malic enzyme, pyruvate carboxylation, and mitochondrial malate import in glucose-stimulated insulin secretion. PubMed: Characterization of Desulfomicrobium salsuginis sp. nov. and Desulfomicrobium aestuarii sp. nov., two new sulfate-reducing bacteria isolated from the Adour estuary (French Atlantic coast) with specific mercury methylation potentials. PubMed: Alteration of DMBA-induced oxidative stress by additive action of a modified indigenous preparation--Kalpaamruthaa. PubMed: Restorative effect of Kalpaamruthaa, an indigenous preparation, on oxidative damage in mammary gland mitochondrial fraction in experimental mammary carcinoma. PubMed: Enthalpy change on mixing a couple of S- and R-enantiomers of some chiral compounds at 298.15 K. PubMed: Gateways to clinical trials. PubMed: Therapeutic effect of tamoxifen and energy-modulating vitamins on carbohydrate-metabolizing enzymes in breast cancer. PubMed: A rapid screening method to detect specific inhibitors of pyruvate orthophosphate dikinase as leads for C4 plant-selective herbicides. PubMed: Anthelmintic efficacy of Flemingia vestita (Fabaceae): alterations in glucose metabolism of the cestode, Raillietina echinobothrida. PubMed: Characterization of photosynthetic electron transport in bundle sheath cells of maize. I. Ascorbate effectively stimulates cyclic electron flow around PSI. PubMed: Biochemical mechanism of lipid-induced impairment of glucose-stimulated insulin secretion and reversal with a malate analogue. PubMed: Mechanism of superoxide anion generation in intact mitochondria in the presence of lucigenin and cyanide. PubMed: Therapeutic effect of Semecarpus anacardium Linn. nut milk extract on carbohydrate metabolizing and mitochondrial TCA cycle and respiratory chain enzymes in mammary carcinoma rats. PubMed: Alpha-cycloPNA: 1-aminocylopentane-1-carboxylic acid-derived peptide nucleic acid. PubMed: Redox changes in the chloroplast and hydrogen peroxide are essential for regulation of C(3)-CAM transition and photooxidative stress responses in the facultative CAM plant Mesembryanthemum crystallinum L. PubMed: Synthesis and characterization of poly(butylene succinate-co-butylene malate): a new biodegradable copolyester bearing hydroxyl pendant groups. PubMed: Differences between mouse and rat pancreatic islets: succinate responsiveness, malic enzyme, and anaplerosis. PubMed: A new approach for asymmetric synthesis of (R)-3-methylpyrrolidine alkaloids from (S)-malic acid. PubMed: Control of dimethylsulfoxide reductase expression in Rhodobacter capsulatus: the role of carbon metabolites and the response regulators DorR and RegA. PubMed: FlhD/FlhC-regulated promoters analyzed by gene array and lacZ gene fusions. PubMed: Monoamine oxidase B inhibitors from the fruits of Opuntia ficus-indica var. saboten. PubMed: Vacuolar chloride transport in Mesembryanthemum crystallinum L. measured using the fluorescent dye lucigenin. PubMed: Biochemical characterization of lucigenin (Bis-N-methylacridinium) as a chemiluminescent probe for detecting intramitochondrial superoxide anion radical production. PubMed: Sulfidogenesis from 2-aminoethanesulfonate (taurine) fermentation by a morphologically unusual sulfate-reducing bacterium, Desulforhopalus singaporensis sp. nov. PubMed: Effects of starvation and diabetes on the metabolism of [2,3-13C]succinic acid dimethyl ester in rat hepatocytes. PubMed: Metabolism of the dimethyl ester of [2,3-(13)C]succinic acid in rat hepatocytes. PubMed: Synthesis and 31P chemical shift identification of tripeptide active site models that represent human serum acetylcholinesterase covalently modified at serine by certain organophosphates. PubMed: NADP-malate dehydrogenase activity in rat erythrocytes. Comparison with pyruvate kinase in relation to coupling with lactate dehydrogenase. PubMed: Feasibility of a mitochondrial pyruvate malate shuttle in pancreatic islets. Further implication of cytosolic NADPH in insulin secretion. PubMed: Counteractive Effects of ABA and GA3 on Extracellular and Intracellular pH and Malate in Barley Aleurone. PubMed: Tri-Calciphor (16,16-dimethyl-15-dehydroprostaglandin B1 trimer)-mediated mitochondrial Ca2+ movements: modulation by phosphate. PubMed: Metabolism of the insulin secretagogue methyl succinate by pancreatic islets. PubMed: Genetic and physiological characterization of the Rhodospirillum rubrum carbon monoxide dehydrogenase system. PubMed: Mechanisms involved in aggravation of ethanol-induced gastric mucosal lesions in adrenalectomized rats. PubMed: 12(R)-hydroxyeicosatrienoic acid: a vasodilator cytochrome P-450-dependent arachidonate metabolite from the bovine corneal epithelium. PubMed: Hydralazine-dependent carbon dioxide free radical formation by metabolizing mitochondria. PubMed: Biochemical alterations in 7,12-dimethylbenz[a]anthracene-induced mammary tumors from rats subjected to caloric restriction. PubMed: Equilibrium constants of several reactions involved in the fermentation of glutamate. PubMed: An improved method for the preparation of rat brain microsomes. PubMed: Effects of glutathione depletion on gluconeogenesis in isolated hepatocytes. PubMed: Methyl parathion (O-O-dimethyl O-4-nitrophenyl thiophosphate) effects on whole-body and tissue respiration in the teleost, Tilapia mossambica (Peters). PubMed: Completion of the degradation scheme for nicotinic acid by Clostridium barkeri. PubMed: Nicotinic acid metabolism. Dimethylmaleate hydratase. PubMed: AMP-dependence of the cyanide-insensitive pathway in the respiratory chain of Paramecium tetraurelia. PubMed: Gluconeogenesis in rat hepatocytes from monomethyl succinate and other esters. PubMed: Nicotinic acid metabolism: stereochemical course of the (2R,3S)-2,3-dimethylmalate lyase reaction. PubMed: Fermentation and anaerobic respiration by Rhodospirillum rubrum and Rhodopseudomonas capsulata. PubMed: Effects of N-dimethyl propranolol (UM-272) on isolated cardiac mitochondria and microsomes. PubMed: pH and bicarbonate effects on mitochondrial anion accumulation. Proposed mechanism for changes in renal metabolite levels in acute acid-base disturbances. PubMed: Light versus Dark Carbon Metabolism in Cherry Tomato Fruits: II. Relationship Between Malate Metabolism and Photosynthetic Activity. PubMed: [Change in lipid-protein interactions in the membranes of bacteria exposed to gramicidin S]. PubMed: Intracellular pH of Thermoplasma acidophila.