dextro,laevo-cycloserine
DL-cycloserine
Identification
| Name | dextro,laevo-cycloserine |
| IUPAC | 4-amino-1,2-oxazolidin-3-one |
| CAS Number | 68-39-3 |
| EINECS | 200-687-9 |
| FDA UNII | Search |
| Molecular Formula | C3 H6 N2 O2 |
| Molecular Weight | 102.09322000 |
| MDL Number | MFCD00064323 |
| Nikkaji Number | J60.873D |
Regulatory
Physical Properties
| Appearance | white to pale yellow crystals (est) |
| Assay | 95.00 to 100.00 |
| Food Chemicals Codex Listed | No |
| Melting Point | 155.00 °C. @ 760.00 mm Hg (est) |
| Flash Point | 32.00 °F. TCC ( 0.00 °C. ) (est) |
| logP (o/w) | -1.840 (est) |
| Soluble in | water, 1.655e+005 mg/L @ 25 °C (est) |
No sensory data available
Safety Information
| Preferred SDS | View |
| Oral/Parenteral Toxicity | intraperitoneal-mouse LD50 3200 mg/kg |
| Dermal Toxicity | Not determined |
| Inhalation Toxicity | Not determined |
GHS Classification
['GHS Classification in accordance with 29 CFR 1910 (OSHA HCS)', 'GHS Label elements, including precautionary statements']
Safety in Use
| Category | information only not used for fragrances or flavors |
| Recommendation for dextro,laevo-cycloserine usage levels up to | not for fragrance use. |
| Recommendation for dextro,laevo-cycloserine flavor usage levels up to | not for flavor use. |
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Potential Uses
Natural Occurrence
Synonyms
4-
amino-1,2-oxazolidin-3-one
4-
amino-3-isoxazolidone
DL-
cycloserine
3-iso
xazolidinone, 4-amino-
PubMed:
Mechanism of synergy between epigallocatechin gallate and beta-lactams against methicillin-resistant Staphylococcus aureus.
PubMed:
The glutathione dependence of inorganic sulfate formation from L- or D-cysteine in isolated rat hepatocytes.
PubMed:
Alanine and hyperosmolarity are responsible for the stimulation of cardiomyocyte glucose transport by samples containing a glucose tolerance factor.
PubMed:
Inhibition of urea-cycle activity by high concentrations of alanine.
PubMed:
Beta-cyanoalanine synthase: purification and characterization.
PubMed:
[Allergic manifestations due to dl-cycloserine (oxamycin)].
PubMed:
[Chemical and microbiological determination of the liberation of antitubercular agents from emulsion and suspension systems. 1. Streptomycin sulfate, rifamycin SV sodium, DL-cycloserine].
PubMed:
[COMPARATIVE STUDY OF THE FUNCTIONAL AND MORPHOLOGICAL CHANGES IN THE CENTRAL NERVOUS SYSTEM OF WHITE RATS FOLLOWING INTERMITTENT ADMINISTRATION OF DL-CYCLOSERINE].
PubMed:
[Comparative study of functional and morphological changes under the action of dl-cycloserine on the central nervous system].
PubMed:
[Relation between dl-cycloserine and d-cycloserine and the effect on the convulsive action of various analeptics].
PubMed:
Inhibition of glutamic-pyruvic transaminase by DL-cycloserine and other compounds.
PubMed:
[Effect of dl-cycloserine on the nervous system].
PubMed:
Formation of DL-cycloserine from the methyl ester of dl-aminoxyalanine.
PubMed:
[Circulation of D-cycloserine & Czechosiovak DL-cycloserine in the organism].
PubMed:
[Formation of dl-cycloserine from beta-hydroxaminoalanine methyl ester].