dextro,laevo-norleucine

DL-a-aminocaproic acid

CAS: 616-06-8 C6 H13 N O2 MW: 131.17501000

Identification

Namedextro,laevo-norleucine
IUPAC2-aminohexanoic acid
CAS Number616-06-8
EINECS210-462-7
FDA UNII5C81BE5GKK
Molecular FormulaC6 H13 N O2
Molecular Weight131.17501000
MDL NumberMFCD00064422
Nikkaji NumberJ1.268H
Beilstein1721748
XlogP3-1.50 (est)

Regulatory

Physical Properties

Assay 95.00 to 100.00
Food Chemicals Codex Listed No
Boiling Point 234.00 °C. @ 760.00 mm Hg (est)
Flash Point 204.00 °F. TCC ( 95.30 °C. ) (est)
logP (o/w) 0.920 (est)
Soluble in water, 1.18E+04 mg/L @ 25 °C (exp)

No sensory data available

Safety Information

Preferred SDSView
Oral/Parenteral ToxicityNot determined
Dermal ToxicityNot determined
Inhalation ToxicityNot determined

GHS Classification

['GHS Classification in accordance with 29 CFR 1910 (OSHA HCS)', 'GHS Label elements, including precautionary statements']

Safety in Use

Categoryinformation only not used for fragrances or flavors
Recommendation for dextro,laevo-norleucine usage levels up tonot for fragrance use.
Recommendation for dextro,laevo-norleucine flavor usage levels up tonot for flavor use.

BOC Sciences

Best of Chemicals Supplier

Quality supplier of research chemicals and biochemicals including inhibitors, building blocks, GMP Products, impurities and metabolites, APIs for Veterinary, Natural Compounds, ADCs, Stem Cell Molecul...

View All Website 1-631-485-4226 account@bocsci.com

Glentham Life Sciences Ltd

The Chemical, Biochemical & Research Essentials Supplier

Glentham Life Sciences is a supplier of fine chemicals and raw materials with warehousing, laboratories and packaging facilities in the UK.

View All Website +44 (0) 1225 667798 info@glentham.com

TCI AMERICA

Moving Your Chemistry Forward

We continuously strive to advance our technology.

View All Website 1-800-423-8616 Sales-US@TCIchemicals.com;

Potential Uses

None Found

Natural Occurrence

not found in nature

Synonyms

2- aminocaproic acid DL-a- aminocaproic acid (±)-2- aminohexanoic acid 2- aminohexanoic acid (+-)-nor leucine D-(-)-nor leucine DL-nor leucine nor leucine, D-(-)- PubMed: Non-physiological amino acid (NPAA) therapy targeting brain phenylalanine reduction: pilot studies in PAHENU2 mice. PubMed: Solid-state phase transitions of DL-aminobutyric acid. PubMed: Size-dependent phase stability of a molecular nanocrystal: a proxy for investigating the early stages of crystallization. PubMed: Solid-state phase transitions in DL-norvaline studied by single-crystal X-ray diffraction. PubMed: Solid-solid phase transitions in DL-norvaline studied by differential scanning calorimetry and Raman spectroscopy. PubMed: Concerted molecular displacements in a thermally-induced solid-state transformation in crystals of DL-norleucine. PubMed: Spontaneous resolution of binary copper(II) complexes with racemic dipeptides: crystal structures of glycyl-L-alpha-amino-n-butyrato copper(II) monohydrate, glycyl-D-valinato copper(II) hemihydrate, and glycyl-L-valinato copper(II) hemihydrate. PubMed: Burkholderia fungorum sp. nov. and Burkholderia caledonica sp. nov., two new species isolated from the environment, animals and human clinical samples. PubMed: Subsite preferences of pepstatin-insensitive carboxyl proteinases from prokaryotes: kumamolysin, a thermostable pepstatin-insensitive carboxyl proteinase. PubMed: Separations of enantiomers by preparative capillary isotachophoresis. PubMed: The effect of chlorambucil upon lysozyme activity. PubMed: Identification of carboxyl residues in pepstatin-insensitive carboxyl proteinase from Pseudomonas sp. 101 that participate in catalysis and substrate binding. PubMed: Substrate specificities of pepstatin-insensitive carboxyl proteinases from gram-negative bacteria. PubMed: Characterisation of a thermostable pepstatin-insensitive acid proteinase from a Bacillus sp. PubMed: A pepstatin-insensitive aspartic proteinase from a thermophilic Bacillus sp. PubMed: Purification and some properties of a protease from Streptomyces limosus. PubMed: Purification and characterization of an acid proteinase from Dirofilaria immitis worms. PubMed: Effect of inhibitors of cell envelope synthesis on beta-sitosterol side chain degradation by Mycobacterium sp. NRRL MB 3683. PubMed: Purification and characterization of kumamolysin, a novel thermostable pepstatin-insensitive carboxyl proteinase from Bacillus novosp. MN-32. PubMed: Amino acid imbalance and intracellular protein synthesis. PubMed: The gene and deduced protein sequences of the zymogen of Aspergillus niger acid proteinase A. PubMed: Enhancement of drug susceptibility of Mycobacterium avium by inhibitors of cell envelope synthesis. PubMed: Purification and Characterization of an Extracellular Acid Proteinase from the Ectomycorrhizal Fungus Hebeloma crustuliniforme. PubMed: Methionine as methyl-group donor in the synthesis of Mycobacterium avium envelope lipids, and its inhibition by DL-ethionine, D-norleucine and DL-norleucine. PubMed: Tuna pepsinogens and pepsins. Purification, characterization and amino-terminal sequences. PubMed: Cathepsin D from human leukocytes. Purification by affinity chromatography and properties of the enzyme. PubMed: Purification and properties of a pepstatin-insensitive carboxyl proteinase from a gram-negative bacterium. PubMed: Interference by methionine on valine uptake in Acremonium chrysogenum. PubMed: Purification of an acid protease from Mucor rouxii that inactivates chitin synthetase. PubMed: Amino acid derived latent isocyanates: irreversible inactivation of porcine pancreatic elastase and human leukocyte elastase. PubMed: Extracellular proteinases of the isolate of Botrytis cinerea virulent to apple tissues. PubMed: Acid proteinase activity in fish--I. Comparative study of extraction of cathepsins B and D from Mujil auratus. PubMed: Purification and characterization of pepsinogens and pepsins from Asiatic black bear, and amino acid sequence determination of the NH2-terminal 60 residues of the major pepsinogen. PubMed: Identification of monkey lung procathepsin D-II as a pepsinogen-C-like acid protease zymogen. PubMed: An aspartic proteinase from Fusarium moniliforme. Purification and general properties. PubMed: Extracellular acid proteases produced by Saccharomycopsis lipolytica. PubMed: Aspartyl proteinase from cucumber (Cucumis sativus) seeds. Preparation and characteristics. PubMed: Protease activity associated with loss of adhesiveness in mouse teratocarcinoma. PubMed: Proton magnetic resonance spectroscopy of an essential histidyl residue in a milk-clotting acid protease, Mucor rennin. PubMed: Aryl-L-aminoacylamidase activities in extracts of Streptococcus durans. PubMed: Photo-oxidation of a histidyl residue of milk-clotting acid protease, Mucor rennin. PubMed: Studies on proteinases from the digestive organs of sardine. II. Purification and characterization of two acid proteinases from the stomach. PubMed: Purification and properties of proteinase A from yeast. PubMed: Cathepsins D from rhesus monkey lung. Purification and characterization. PubMed: Monkey pepsinogens and pepsins. Monkey pepsinogens and pepsins. V. Purification, Characterization, and amino-terminal sequence determination of crab-eating monkey pepsinogens and pepsins. PubMed: [Acid proteinase of chicken liver. Purification and properties (author's transl)]. PubMed: A cathepsin D-like acid proteinase from human gastric mucosa. Purification and characterization. PubMed: Inhibition of the acid proteinase from Neurospora crassa by diazoacetyl-DL-norleucine methyl ester, 1,2-epoxy-3-(4-nitrophenoxy)propane and pepstatin. PubMed: Purification and characterization of rat pepsinogens whose contents increase with developmental progress. PubMed: The structure and function of acid proteases. IX. Isolation and amino acid sequences of the peptides containing the active site aspartyl residues reactive with diazoacetyl-DL-norleucine methyl ester and 1,2-epoxy-3-(p-nitrophenoxy)propane in Rhizopus chinensis acid protease. PubMed: Nonsteroid anti-inflammatory agents: regulators of the phagocytic secretion of lysosomal enzymes from guinea-pig neutrophils. PubMed: Inactivation of cathepsin D from human gastric mucosa and from stomach carcinoma by diazoacetyl-DL-norleucine methyl ester. PubMed: Acid proteases. II. Fluorescence study of the interaction of Cladosporium acid protease with glycyl-DL-norleucine methyl ester in the presence of cupric ions. PubMed: The structure and function of acid proteases. VIII. Purification and characterization of cathepsins D from Japanese monkey lung. PubMed: Acid proteases. I. Inactivation of Cladosporium acid protease by diazoacetyl-DL-norleucine methyl ester as an active-site-directed irreversible inhibitor. PubMed: Sulfur metabolism of a mutant of Cephalosporium acremonium with enhanced potential to utilize sulfate for cephalosporin C production. PubMed: Pepsinogen C and pepsin C from gastric mucosa of Japanese monkey. Purification and characterization. PubMed: The structure and function of acid proteases. VI. Effects of acid protease-specific inhibitors on the acid proteases from Aspergillus niger var. macrosporus. PubMed: The structure and function of acid proteases. V. Comparative studies on the specific inhibition of acid proteases by diazoacetyl-DL-norleucine methyl ester, 1,2-epoxy-3-(p-nitrophenoxy) propane and pepstatin. PubMed: The structure and function of acid proteases. IV. Inactivation of the acid protease from Mucor pusillus by acid protease-specific inhibitors. PubMed: Pepsinogens and pepsins from gastric mucosa of Japanese Monkey. Purification and characterization. PubMed: Purification and properties of the thermostable acid protease of Penicillium duponti. PubMed: Effect of norleucine on mycelial fragmentation in Cephalosporium acremonium. PubMed: The relevance of the structure of lysine bound to Sepharose for the affinity of rabbit plasminogen;. PubMed: Specific inhibition of acid proteases from brain, kidney, skeletal muscle, and insectivorous plants by diazoacetyl-DL-norleucine methyl ester and by pepstatin. PubMed: Kinetics of irreversible enzyme inhibition by an unstable inhibitor. PubMed: The structure and function of acid proteases. Specific inactivation of an acid protease from Rhizopus chinensis by diazoacetyl-DL-norleucine methyl ester. PubMed: An active site peptide from pepsin C. PubMed: Amino acid cross resistance in Agrobacterium tumefaciens. PubMed: Biosynthesis of chloramphenicol. IV. Incorporation of carbon 14-labled precursors. PubMed: Nitrogenous compounds in germination and postgerminative development of Bacillus megaterium spores. PubMed: Induced alterations in metabolism of DL-norleucine-2-C14 in the intact cow. PubMed: Metabolism of DL-alpha-aminobutyrate-3-14C and DL-norleucine-3-14C.