docosanoic acid
N-docosanoic acid
Identification
| Name | docosanoic acid |
| IUPAC | docosanoic acid |
| CAS Number | 112-85-6 |
| EINECS | 204-010-8 |
| FDA UNII | H390488X0A |
| Molecular Formula | C22 H44 O2 |
| Molecular Weight | 340.59108000 |
| MDL Number | MFCD00002807 |
| Nikkaji Number | J2.461I |
| Beilstein | 1792887 |
| XlogP3 | 9.60 (est) |
Regulatory
| FDA/DG SANTE Petitions, Reviews, Notices | GRN 69 |
| DG SANTE Food Contact Materials | behenic acid |
Physical Properties
| Appearance | white waxy solid (est) |
| Assay | 95.00 to 100.00 |
| Food Chemicals Codex Listed | No |
| Melting Point | 81.00 °C. @ 760.00 mm Hg |
| Boiling Point | 391.00 to 392.00 °C. @ 760.00 mm Hg (est), 306.00 °C. @ 60.00 mm Hg |
| Flash Point | 349.00 °F. TCC ( 176.30 °C. ) (est) |
| logP (o/w) | 9.910 |
| Soluble in | water, 0.016 mg/L @ 25 °C (exp) |
Cosmetic Information
| CosIng | cosmetic data |
| Cosmetic Uses | cleansing agents |
No sensory data available
Safety Information
| Preferred SDS | View |
| Oral/Parenteral Toxicity | Not determined |
| Dermal Toxicity | Not determined |
| Inhalation Toxicity | Not determined |
GHS Classification
['GHS Classification in accordance with 29 CFR 1910 (OSHA HCS)', 'GHS Label elements, including precautionary statements']
Safety in Use
| Category | food additive and cosmetic agents |
| Recommendation for docosanoic acid usage levels up to | not for fragrance use. |
| Recommendation for docosanoic acid flavor usage levels up to | not for flavor use. |
BOC Sciences
Best of Chemicals Supplier
Quality supplier of research chemicals and biochemicals including inhibitors, building blocks, GMP Products, impurities and metabolites, APIs for Veterinary, Natural Compounds, ADCs, Stem Cell Molecul...
ECSA Chemicals
Human Chemistry
ECSA Chemicals has been active since 1913 in the trading and international commerce of raw materials. With an organisation divided into industrial segments managed by specialists, it has become one of...
Potential Uses
Natural Occurrence
Synonyms
behenic acid
docosanoic acid
1-
docosanoic acid
N-
docosanoic acid
docosanoicacid
docosoic acid
hystrene 3022
PubMed:
Evidence for two enzymatic pathways for omega-oxidation of docosanoic acid in rat liver microsomes.
PubMed:
[Technic of determination by gas-liquid chromatography of a mixture of fatty acids, from butyric acid to docosanoic acid].
PubMed:
Dietary intake and plasma metabolomic analysis of polyunsaturated fatty acids in bipolar subjects reveal dysregulation of linoleic acid metabolism.
PubMed:
[Chemical constituents from seeds of Ziziphus mauritiana].
PubMed:
A new triterpenoid from Sapium baccatum (Euphorbiaceae).
PubMed:
Ethnopharmacological and bioactivity guided investigation of five TCM anticancer herbs.
PubMed:
Detection and identification of extra virgin olive oil adulteration by GC-MS combined with chemometrics.
PubMed:
Docosahexaenoic acid elevates trans-18:1 isomers but is not directly converted into trans-18:1 isomers in ruminal batch cultures.
PubMed:
Design of selective production of sophorolipids by Rhodotorula bogoriensis through nutritional requirements.
PubMed:
Cyclic glycolipids from glandular trichome exudates of Cerastium glomeratum.
PubMed:
The interactions of amphiphilic antisense oligonucleotides with serum proteins and their effects on in vitro silencing activity.
PubMed:
A mixture of oleic, erucic and conjugated linoleic acids modulates cerebrospinal fluid inflammatory markers and improve somatosensorial evoked potential in X-linked adrenoleukodystrophy female carriers.
PubMed:
Antioxidant and antimicrobial activities of ethyl acetate extract, fractions and compounds from stem bark of Albizia adianthifolia (Mimosoideae).
PubMed:
[Analysis of fatty acids in leaves of Loropetalum chinense and L. chinense var. rubrum by GC-MS].
PubMed:
A new flavonol glucoside from the aerial parts of Sida glutinosa.
PubMed:
Fatty acid derivatives and dammarane triterpenes from the glandular trichome exudates of Ibicella lutea and Proboscidea louisiana.
PubMed:
[Study on the chemical constituents of Phellinus lonicerinus].
PubMed:
Structural profiling and quantification of sphingomyelin in human breast milk by HPLC-MS/MS.
PubMed:
[A novel mutation in PEX 26 gene in Zellweger syndrome: a case report].
PubMed:
Liposome-incorporated DHA increases neuronal survival by enhancing non-amyloidogenic APP processing.
PubMed:
Metabolomics of gastric cancer metastasis detected by gas chromatography and mass spectrometry.
PubMed:
[Studies on the chemical constituents of Toricellia angulata var. intermedia].
PubMed:
Screening assay of very long chain fatty acids in human plasma with multiwalled carbon nanotube-based surface-assisted laser desorption/ionization mass spectrometry.
PubMed:
Pure and mixed films of a nitrostilbene derivative at the air-water interface, Langmuir-Blodgett multilayer fabrication, and optical characterization.
PubMed:
[Studies on the chemical constituents of the petroleum ether portion of Nervilia fordii].
PubMed:
A study of bone marrow and subcutaneous fatty acid composition in subjects of varying bone mineral density.
PubMed:
Chlamydomonas as a "new" organism for biodiesel production.
PubMed:
Evolution toward the X phase of fatty acid Langmuir monolayers on a divalent cation solution.
PubMed:
Byrsonic acid--the clue to floral mimicry involving oil-producing flowers and oil-collecting bees.
PubMed:
A simple method to diagnose adrenoleukodystrophy using a dried blood spot on filter paper.
PubMed:
The correlation between biochemical and histopathological findings in adrenoleukodystrophy.
PubMed:
DETERMINATION OF STEAM-VOLATILE ORGANIC ACIDS IN FERMENTATION MEDIA BY GAS-LIQUID CHROMATOGRAPHY.
PubMed:
Analysis of sterols and fatty acids in natural and cultured Cordyceps by one-step derivatization followed with gas chromatography-mass spectrometry.
PubMed:
The DAISY gene from Arabidopsis encodes a fatty acid elongase condensing enzyme involved in the biosynthesis of aliphatic suberin in roots and the chalaza-micropyle region of seeds.
PubMed:
[Determination of fatty acids and organic acids in Ranunculus ternatus Thunb using GC-MS].
PubMed:
Amylose-lipid complexes as controlled lipid release agents during starch gelatinization and pasting.
PubMed:
Simultaneous determination of saponins and fatty acids in Ziziphus jujuba (Suanzaoren) by high performance liquid chromatography-evaporative light scattering detection and pressurized liquid extraction.
PubMed:
Proton sponge and fatty acid interactions at the air-water interface. Thermodynamic, spectroscopic, and microscopic study.
PubMed:
Membrane fluidity changes are associated with the antiarrhythmic effects of docosahexaenoic acid in adult rat cardiomyocytes.
PubMed:
Ultrathin polymer film formation by collision-induced cross-linking of adsorbed organic molecules with hyperthermal protons.
PubMed:
[Studies on chemical constituents of Alpinia jianganfeng].
PubMed:
Pentacyclic triterpenoids from the aerial parts of Lantana camara.
PubMed:
Polycations increase the permeability of Mycobacterium vaccae cell envelopes to hydrophobic compounds.
PubMed:
Termination of asynchronous contractile activity in rat atrial myocytes by n-3 polyunsaturated fatty acids.
PubMed:
Mycobacterium xenopi and related organisms isolated from stream waters in Finland and description of Mycobacterium botniense sp. nov.
PubMed:
Use of gas chromatographic fatty acid and mycolic acid cleavage product determination to differentiate among Mycobacterium genavense, Mycobacterium fortuitum, Mycobacterium simiae, and Mycobacterium tuberculosis.
PubMed:
Determination of total long-chain fatty acids in human plasma and lipoproteins, before and during copper-stimulated oxidation, by high-performance liquid chromatography.
PubMed:
Isolation of Mycobacterium malmoense from the environment in Zaire.
PubMed:
Bio-anticlastogenic effects of unsaturated fatty acids included in fish oil--docosahexaenoic acid, docosapentaenoic acid, and eicosapentaenoic acid--in cultured Chinese hamster cells.
PubMed:
Occurrence of ceramide digalactoside as the main glycosphingolipid in the marine sponge Halichondria japonica.
PubMed:
[Chemical constituents of the seed oil of Astragalus complanatus R. Brown].
PubMed:
Mycolic acids of Mycobacterium aurum. Structure and biogenetic implications.
PubMed:
Adrenoleukodystrophy in a mother and son.
PubMed:
Adrenoleukodystrophy. Report of an autopsy case with adrenoleukomyeloneuropathy.
PubMed:
Determination of C20-C30 fatty acids by reversed-phase chromatographic techniques: an efficient method to quantitate minor fatty acids in serum of patients with adrenoleukodystrophy.
PubMed:
Regulation of hydroxydocosanoic acid sophoroside production in Candida bogoriensis by the levels of glucose and yeast extract in the growth medium.
PubMed:
Acetylation of 13-sophorosyloxydocosanoic acid by an acetyltransferase purified from Candida bogoriensis.
PubMed:
Stability of fatty acid monolayers and the relationship between equilibrium spreading pressure, phase transformations, and polymorphic crystal forms.
PubMed:
The inhibitory action of long-chain fatty acids on the DNA binding activity of p53.
PubMed:
Characterization of Armillaria spp. from peach orchards in the southeastern United States using fatty acid methyl ester profiling.
PubMed:
Potato phosphorylase catalyzed synthesis of amylose-lipid complexes.
PubMed:
Four new prenylated isoflavonoids in Tadehagi triquetrum.
PubMed:
[Determination of fatty acids in Malania oleifera oil by gas chromatography-mass spectrometry].
PubMed:
Biosynthesis and structural characterization of medium-chain-length poly(3-hydroxyalkanoates) produced by Pseudomonas aeruginosa from fatty acids.
PubMed:
Plasma very long chain fatty acids in 3,000 peroxisome disease patients and 29,000 controls.
PubMed:
Glycoinositol phospholipids from Endotrypanum species express epitopes in common with saccharide side chains of the lipophosphoglycan from Leishmania major.
PubMed:
Anti-herpes simplex virus activity of n-docosanol correlates with intracellular metabolic conversion of the drug.
PubMed:
Profiles of very-long-chain fatty acids in plasma, fibroblasts, and blood cells in Zellweger syndrome, X-linked adrenoleukodystrophy, and rhizomelic chondrodysplasia punctata.
PubMed:
Schizophrenic patients treated with high dose phenothiazine or thioxanthene become deficient in polyunsaturated fatty acids in their thrombocytes.
PubMed:
Antimalarial properties of n-3 and n-6 polyunsaturated fatty acids: in vitro effects on Plasmodium falciparum and in vivo effects on P. berghei.
PubMed:
A human membrane-associated folate binding protein is anchored by a glycosyl-phosphatidylinositol tail.
PubMed:
[Studies on the chemical constituents of Schizonepeta mulifida (L.) Briq].
PubMed:
Very long-chain fatty acids in erythrocyte membrane sphingomyelin: detection of ALD hemizygotes and heterozygotes.
PubMed:
Abnormality of long-chain fatty acids in erythrocyte membrane sphingomyelin from patients with adrenoleukodystrophy.
PubMed:
Characterization and in vivo production of three glycolipids from Candida Bogoriensis: 13-glucopyranosylglucopyranosyloxydocosanoic acid and its mono- and diacetylated derivatives.
PubMed:
The effect of wax components on cuticular transpiration-model experiments.