ellipticine
6H-pyrido(4,3-b)carbazole, 5,11-dimethyl-
Identification
| Name | ellipticine |
| IUPAC | 5,11-dimethyl-6H-pyrido[4,3-b]carbazole |
| CAS Number | 519-23-3 |
| EINECS | 208-264-0 |
| FDA UNII | 117VLW7484 |
| Molecular Formula | C17 H14 N2 |
| Molecular Weight | 246.31258000 |
| MDL Number | MFCD00010524 |
| Nikkaji Number | J6.591I |
| Beilstein | 0221300 |
| XlogP3 | 4.80 (est) |
Regulatory
Physical Properties
| Assay | 95.00 to 100.00 |
| Food Chemicals Codex Listed | No |
| Melting Point | 313.00 °C. @ 760.00 mm Hg |
| Boiling Point | 495.40 °C. @ 760.00 mm Hg (est) |
| Flash Point | 441.00 °F. TCC ( 227.10 °C. ) (est) |
| logP (o/w) | 4.800 |
| Soluble in | water, 0.1532 mg/L @ 25 °C (est) |
No sensory data available
Safety Information
| Oral/Parenteral Toxicity | intraperitoneal-mouse LD50 150 mg/kg |
| Dermal Toxicity | Not determined |
| Inhalation Toxicity | Not determined |
GHS Classification
['GHS Classification in accordance with 29 CFR 1910 (OSHA HCS)', 'GHS Label elements, including precautionary statements']
Safety in Use
| Category | natural substances and extractives |
| Recommendation for ellipticine usage levels up to | not for fragrance use. |
| Recommendation for ellipticine flavor usage levels up to | not for flavor use. |
BOC Sciences
Best of Chemicals Supplier
Quality supplier of research chemicals and biochemicals including inhibitors, building blocks, GMP Products, impurities and metabolites, APIs for Veterinary, Natural Compounds, ADCs, Stem Cell Molecul...
Potential Uses
Natural Occurrence
Synonyms
celiptium
CP 5
5,11-
dimethyl-6H-pyrido(4,3-b)carbazole
elliptisine
6H-
pyrido(4,3-b)carbazole, 5,11-dimethyl-
tcmdc-125546
PubMed:
Tolbutamide hydroxylation by hepatic microsomes from Atlantic salmon (Salmo salar L.).
PubMed:
A high content drug screen identifies ursolic acid as an inhibitor of amyloid beta protein interactions with its receptor CD36.
PubMed:
Para-nitrophenol hydroxylation by fish liver microsomes: kinetics and effect of selective cytochrome P450 inhibitors.
PubMed:
EROD and MROD as Markers of Cytochrome P450 1A Activities in Hepatic Microsomes from Entire and Castrated Male Pigs.
PubMed:
Differential response of cultured human umbilical vein and artery endothelial cells to Ah receptor agonist treatment: CYP-dependent activation of food and environmental mutagens.
PubMed:
Major involvement of rabbit liver cytochrome P4501A in thiabendazole 5-hydroxylation.
PubMed:
Metabolic activation of the food mutagen 3-amino-1,4-dimethyl-5H-pyrido-[4,3-b]indole (Trp-P-1) in endothelial cells of cytochrome P-450-induced mice.
PubMed:
Metabolic activation of the food mutagen Trp-P-1 in endothelial cells of heart and kidney in cytochrome P450-induced mice.
PubMed:
In vitro metabolism of teratogens by differentiating rat embryo cells.