epsilon-caprolactone
hexamethylene oxide, 2-oxo-
Identification
| Name | epsilon-caprolactone |
| IUPAC | oxepan-2-one |
| CAS Number | 502-44-3 |
| EINECS | 207-938-1 |
| FDA UNII | 56RE988L1R |
| Molecular Formula | C6 H10 O2 |
| Molecular Weight | 114.14410000 |
| MDL Number | MFCD00003267 |
| Nikkaji Number | J1.566K |
| Beilstein | 0106919 |
Regulatory
| DG SANTE Food Contact Materials | caprolactone |
Physical Properties
| Appearance | colorless to pale yellow clear liquid (est) |
| Assay | 95.00 to 100.00 |
| Food Chemicals Codex Listed | No |
| Specific Gravity | 1.03000 @ 25.00 °C. |
| Melting Point | -1.00 °C. @ 760.00 mm Hg |
| Boiling Point | 215.00 °C. @ 760.00 mm Hg, 140.00 °C. @ 35.00 mm Hg |
| Vapor Pressure | 0.135000 mmHg @ 25.00 °C. |
| Flash Point | 229.00 °F. TCC ( 109.44 °C. ) |
| logP (o/w) | 0.422 (est) |
| Soluble in | water, 2.786e+004 mg/L @ 25 °C (est) |
No sensory data available
Safety Information
| Preferred SDS | View |
| Oral/Parenteral Toxicity | oral-rat LD50 4290 mg/kg |
| Dermal Toxicity | skin-rabbit LD50 5990 ul/kg |
| Inhalation Toxicity | Not determined |
GHS Classification
['GHS Classification in accordance with 29 CFR 1910 (OSHA HCS)', 'GHS Label elements, including precautionary statements']
Safety in Use
| Category | indirect food additives: adhesives and components of coatings |
| Recommendation for epsilon-caprolactone usage levels up to | not for fragrance use. |
| Recommendation for epsilon-caprolactone flavor usage levels up to | not for flavor use. |
BOC Sciences
Best of Chemicals Supplier
Quality supplier of research chemicals and biochemicals including inhibitors, building blocks, GMP Products, impurities and metabolites, APIs for Veterinary, Natural Compounds, ADCs, Stem Cell Molecul...
Charkit Chemical Corporation
The Specialty Chemical Specialists
Explore this website to discover the products and services that Charkit provides for your industry and please contact us directly to find out how we can be of service to you.
Penta International Corporation
Chemistry innovation
At Penta, our products and services help businesses do business better.
Potential Uses
Natural Occurrence
Synonyms
caprolactone
1-oxa-2-oxo
cycloheptane
2-oxa
cycloheptanone
2-oxo
hexamethylene oxide
hexamethylene oxide, 2-oxo-
hexan-6-olide
6-
hexanolactone
1,6-
hexanolide
6-
hexanolide
6-
hydroxyhexan-6-olide
6-
hydroxyhexanoic acid lactone
oxepan-2-one
2-
oxepanone
placcel M
PubMed:
Enhanced Production of epsilon-Caprolactone by Coexpression of Bacterial Hemoglobin Gene in Recombinant Escherichia coli Expressing Cyclohexanone Monooxygenase Gene.
PubMed:
Biocatalytic synthesis of δ-gluconolactone and ε-caprolactone copolymers.
PubMed:
Controlled protein delivery from electrospun non-wovens: novel combination of protein crystals and a biodegradable release matrix.
PubMed:
Characterization of poly(ε-caprolactone)-based nanocomposites containing hydroxytyrosol for active food packaging.
PubMed:
Dual-Component System Dimethyl Sulfoxide/LiCl as a Solvent and Catalyst for Homogeneous Ring-Opening Grafted Polymerization of ε-Caprolactone onto Xylan.
PubMed:
Reversal of multidrug resistance by the inhibition of ATP-binding cassette pumps employing "Generally Recognized As Safe" (GRAS) nanopharmaceuticals: A review.
PubMed:
Characterisation and stability evaluation of bixin nanocapsules.
PubMed:
Active systems based on silver-montmorillonite nanoparticles embedded into bio-based polymer matrices for packaging applications.
PubMed:
Productivity of cyclohexanone oxidation of the recombinant Corynebacterium glutamicum expressing chnB of Acinetobacter calcoaceticus.
PubMed:
Development of nanostructured thermoregulating textile materials.
PubMed:
Diversity of bacterial isolates from commercial and homemade composts.
PubMed:
Polyester-degrading thermophilic actinomycetes isolated from different environment in Taiwan.
PubMed:
PLGA 90/10 and caprolactone biodegradable nerve guides for the reconstruction of the rat sciatic nerve.
PubMed:
Effects of chronic administration of naltrexone on appetitive behaviors of rats.