ethyl amine
ethylamine
Identification
| Name | ethyl amine |
| IUPAC | ethanamine |
| CAS Number | 75-04-7 |
| EINECS | 200-834-7 |
| FDA UNII | YG6MGA6AT5 |
| Molecular Formula | C2 H7 N |
| Molecular Weight | 45.08479000 |
| MDL Number | MFCD00008160 |
| Nikkaji Number | J1.437K |
| Beilstein | 0505933 |
| CoE Number | 10477 |
Regulatory
| JECFA Food Flavoring | 1579 ethylamine |
| DG SANTE Food Flavourings | 11.015 ethylamine |
| FEMA Number | 4236 |
| FDA | No longer provide for the use of these seven synthetic flavoring substances |
| FDA Mainterm (SATF) | 75-04-7 ; ETHYLAMINE |
Physical Properties
| Appearance | colorless to yellow gas (est) |
| Assay | 95.00 to 100.00 |
| Food Chemicals Codex Listed | No |
| Specific Gravity | 0.68200 to 0.68600 @ 25.00 °C. |
| Pounds per Gallon - (est). | 5.675 to 5.708 |
| Melting Point | -81.00 to -80.00 °C. @ 760.00 mm Hg |
| Boiling Point | 16.00 to 17.00 °C. @ 760.00 mm Hg |
| Vapor Pressure | 1132.333008 mmHg @ 25.00 °C. (est) |
| Flash Point | 1.00 °F. TCC ( -17.22 °C. ) |
| logP (o/w) | -0.130 |
| Soluble in | propylene glycol |
Organoleptic Properties
| Odor Description | at 0.01 % in propylene glycol. |
| Odor sample from | Sigma-Aldrich |
Safety Information
| Preferred SDS | View |
| European information | Most important hazard(s): |
| Oral/Parenteral Toxicity | intravenous-rabbit LDLo 350 mg/kg |
| Dermal Toxicity | skin-rabbit LD50 390 uL/kg |
| Inhalation Toxicity | inhalation-mammal (species unspecified) LC50 2300 mg/m3 |
GHS Classification
['GHS Classification in accordance with 29 CFR 1910 (OSHA HCS)', 'GHS Label elements, including precautionary statements']
Safety in Use
| Category | flavoring agents |
| Recommendation for ethyl amine usage levels up to | not for fragrance use. |
| Maximised Survey-derived Daily Intakes (MSDI-EU) | 0.012 (μg/capita/day) |
| Maximised Survey-derived Daily Intakes (MSDI-USA) | 0.20 (μg/capita/day) |
| Modified Theoretical Added Maximum Daily Intake (mTAMDI) | 340 (μg/person/day) |
| Threshold of Concern | 1800 (μg/person/day) |
| Structure Class | I |
| baked goods | 2.00000 |
| beverages(nonalcoholic) | - |
| beverages(alcoholic) | - |
| breakfast cereal | 0.20000 |
| cheese | 0.40000 |
| chewing gum | - |
| condiments / relishes | 0.10000 |
| confectionery froastings | 1.00000 |
| egg products | - |
| fats / oils | 0.10000 |
| fish products | 0.20000 |
| frozen dairy | 0.40000 |
| fruit ices | 0.40000 |
| gelatins / puddings | - |
| granulated sugar | - |
| gravies | 0.10000 |
| hard candy | - |
| imitation dairy | - |
| instant coffee / tea | - |
| jams / jellies | - |
| meat products | 0.20000 |
| milk products | 0.40000 |
| nut products | - |
| other grains | 0.20000 |
| poultry | 0.20000 |
| processed fruits | 0.40000 |
| processed vegetables | - |
| reconstituted vegetables | - |
| seasonings / flavors | 0.10000 |
| snack foods | 1.00000 |
| soft candy | - |
| soups | 0.10000 |
| sugar substitutes | - |
| sweet sauces | - |
| Dairy products, excluding products of category 02.0 (01.0) | 0.40000 |
| Fats and oils, and fat emulsions (type water-in-oil) (02.0) | 0.10000 |
| Edible ices, including sherbet and sorbet (03.0) | 0.40000 |
| Processed fruit (04.1) | 0.40000 |
| Processed vegetables (incl. mushrooms & fungi, roots & tubers, pulses and legumes), and nuts & seeds (04.2) | - |
| Confectionery (05.0) | 1.00000 |
| Chewing gum (05.3) | - |
| Cereals and cereal products, incl. flours & starches from roots & tubers, pulses & legumes, excluding bakery (06.0) | 0.20000 |
| Bakery wares (07.0) | 2.00000 |
| Meat and meat products, including poultry and game (08.0) | 0.20000 |
| Fish and fish products, including molluscs, crustaceans and echinoderms (MCE) (09.0) | 0.20000 |
| Eggs and egg products (10.0) | - |
| Sweeteners, including honey (11.0) | - |
| Salts, spices, soups, sauces, salads, protein products, etc. (12.0) | 0.10000 |
| Foodstuffs intended for particular nutritional uses (13.0) | 0.20000 |
| Non-alcoholic ("soft") beverages, excl. dairy products (14.1) | - |
| Alcoholic beverages, incl. alcohol-free and low-alcoholic counterparts (14.2) | 1.00000 |
| Ready-to-eat savouries (15.0) | 1.00000 |
| Composite foods (e.g. casseroles, meat pies, mincemeat) - foods that could not be placed in categories 01.0 - 15.0 (16.0) | 0.20000 |
Penta International Corporation
Chemistry innovation
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Potential Uses
Natural Occurrence
Synonyms
aminoethane
1-
aminoethane
ethanamine
mono
ethyl amine
N-
ethyl amine
ethylamine
mono
ethylamine
Info:
aliphatic and aromatic amines and amides
PubMed:
Nitrogen fertilisation increases biogenic amines and amino acid concentrations in Vitis vinifera var. Riesling musts and wines.
PubMed:
Sensing of amino acids by the gut-expressed taste receptor T1R1-T1R3 stimulates CCK secretion.
PubMed:
Kinetics of L-theanine uptake and metabolism in healthy participants are comparable after ingestion of L-theanine via capsules and green tea.
PubMed:
Levels of biogenic amines in retail market fermented meat products.
PubMed:
Effective separation of dopamine from bananas on 2-(3,4-dimethoxyphenyl)ethylamine imprinted polymer.
PubMed:
Antioxidant activity of Moringa oleifera tissue extracts.
PubMed:
Effects of amines and aminoalcohols on bovine intestine alkaline phosphatase activity.
PubMed:
Assessment of the genetic polymorphism and biogenic amine production of indigenous Oenococcus oeni strains isolated from Greek red wines.
PubMed:
Decreases in cocaine self-administration with dual inhibition of the dopamine transporter and Ï receptors.
PubMed:
Gas chromatography-mass spectrometry assessment of amines in Port wine and grape juice after fast chloroformate extraction/derivatization.
PubMed:
Calcimimetics inhibit renal pathology in rodent nephronophthisis.
PubMed:
Purification and characterization of γ-glutamyltranspeptidase from Bacillus subtilis SK11.004.
PubMed:
Discovery and evaluation of pyrazolo[1,5-a]pyrimidines as neuropeptide Y1 receptor antagonists.
PubMed:
Development of efficient enzymatic production of theanine by γ-glutamyltranspeptidase from a newly isolated strain of Bacillus subtilis, SK11.004.
PubMed:
Rhodotorula taiwanensis sp. nov., a novel yeast species from a plant in Taiwan.
PubMed:
Development of a gas chromatography method for the estimation of alkylamines in foods.
PubMed:
Enzymatic synthesis of theanine from glutamic acid γ-methyl ester and ethylamine by immobilized Escherichia coli cells with γ-glutamyltranspeptidase activity.
PubMed:
Determination of biogenic amines in Korean traditional fermented soybean paste (Doenjang).
PubMed:
Reinforcing effects of sigma-receptor agonists in rats trained to self-administer cocaine.
PubMed:
A new ultra-pressure liquid chromatography method for the determination of biogenic amines in cheese.
PubMed:
Selective reduction of alcohol drinking in Sardinian alcohol-preferring rats by a sigma-1 receptor antagonist.
PubMed:
Biogenic amines in natural ciders.
PubMed:
Expression optimization and biochemical characterization of a recombinant gamma-glutamyltranspeptidase from Escherichia coli novablue.
PubMed:
Formation of biogenic amines throughout the industrial manufacture of red wine.
PubMed:
Acute blood pressure effects and chronic hypotensive action of calcimimetics in uremic rats.
PubMed:
Protection of originality of Tokaji Aszú: amines and organic acids in botrytized wines by high-performance liquid chromatography.
PubMed:
Interactions of organic compounds with wastewater dissolved organic matter: role of hydrophobic fractions.
PubMed:
Interrelationships among microbiological, physicochemical, and biochemical properties of Terrincho cheese, with emphasis on biogenic amines.
PubMed:
Purification and characterization of glutamine synthetase of Pseudomonas taetrolens Y-30: an enzyme usable for production of theanine by coupling with the alcoholic fermentation system of baker's yeast.
PubMed:
Theanine, gamma-glutamylethylamide, is metabolized by renal phosphate-independent glutaminase.
PubMed:
Content of biogenic amines in a Chardonnay wine obtained through spontaneous and inoculated fermentations.
PubMed:
Identification of yeasts present in sour fermented foods and fodders.
PubMed:
Deodorizing effects of tea catechins on amines and ammonia.
PubMed:
Effects of a methanolic extract and a hyperforin-enriched CO2 extract of Hypericum perforatum on alcohol intake in rats.
PubMed:
Ethylamine in human urine.
PubMed:
Volatile compounds thermally generated from S-propylcysteine and S-propylcysteine sulfoxide-aroma precursors of Allium vegetables.
PubMed:
Metabolism of theanine, gamma-glutamylethylamide, in rats.
PubMed:
Time-dependent changes of amino acids in the serum, liver, brain and urine of rats administered with theanine.
PubMed:
Sigma receptor ligands (+)-SKF10,047 and SA4503 improve dizocilpine-induced spatial memory deficits in rats.
PubMed:
Metabolites of N-ethylbenzamide, N,N-diethylbenzamide and related compounds detected in rat urine by NMR spectroscopy.
PubMed:
Nitrosatable amines and nitrosamide formation in natural stimulants: Cola acuminata, C. nitida and Garcinia cola.
PubMed:
Increased exposure to dietary amines and nitrate in a population at high risk of oesophageal and gastric cancer in Kashmir (India).
PubMed:
Quantitative determination of amines in wine by liquid chromatography.
PubMed:
Effects of dietary amines on the small intestine in calves fed soybean protein.
PubMed:
In-vivo activation of N-nitrosodiethanolamine and other n-nitroso-2-hydroxyalkylamines by alcohol dehydrogenase and sulfotransferase.
PubMed:
Abundance of dimethylamine in seafoods: possible implications in the incidence of human cancer.
PubMed:
High concentrations of dimethylamine and methylamine in squid and octopus and their implications in tumour aetiology.
PubMed:
Serum levels of dimenhydrinate. Determination by HPLC with UV detection after intake of dimenhydrinate in a coated chewing gum dragee.
PubMed:
Importance of dietary amines in meal-induced gastrin release.
PubMed:
Dose-response studies in carcinogenesis by nitroso-N-methyl-N-(2-phenyl)ethylamine in rats and the effects of deuterium substitution.
PubMed:
[On the problems in respect ot the formation of N-nitroso compound precursors when using alkylating agents in the fumigation of foodstuffs. I. Investigations of the formation of secondary amines by the action of ethylene oxide on primary amines and amino acids (author's transl)].