Identification

Nameethyl amine
IUPACethanamine
CAS Number75-04-7
EINECS200-834-7
FDA UNIIYG6MGA6AT5
Molecular FormulaC2 H7 N
Molecular Weight45.08479000
MDL NumberMFCD00008160
Nikkaji NumberJ1.437K
Beilstein0505933
CoE Number10477

Regulatory

JECFA Food Flavoring1579 ethylamine
DG SANTE Food Flavourings11.015 ethylamine
FEMA Number4236
FDANo longer provide for the use of these seven synthetic flavoring substances
FDA Mainterm (SATF)75-04-7 ; ETHYLAMINE

Physical Properties

Appearance colorless to yellow gas (est)
Assay 95.00 to 100.00
Food Chemicals Codex Listed No
Specific Gravity 0.68200 to 0.68600 @ 25.00 °C.
Pounds per Gallon - (est). 5.675 to 5.708
Melting Point -81.00 to -80.00 °C. @ 760.00 mm Hg
Boiling Point 16.00 to 17.00 °C. @ 760.00 mm Hg
Vapor Pressure 1132.333008 mmHg @ 25.00 °C. (est)
Flash Point 1.00 °F. TCC ( -17.22 °C. )
logP (o/w) -0.130
Soluble in propylene glycol

Organoleptic Properties

Odor Description at 0.01 % in propylene glycol.
Odor sample from Sigma-Aldrich

Safety Information

Preferred SDSView
European informationMost important hazard(s):
Oral/Parenteral Toxicityintravenous-rabbit LDLo 350 mg/kg
Dermal Toxicityskin-rabbit LD50 390 uL/kg
Inhalation Toxicityinhalation-mammal (species unspecified) LC50 2300 mg/m3

GHS Classification

['GHS Classification in accordance with 29 CFR 1910 (OSHA HCS)', 'GHS Label elements, including precautionary statements']

Safety in Use

Categoryflavoring agents
Recommendation for ethyl amine usage levels up tonot for fragrance use.
Maximised Survey-derived Daily Intakes (MSDI-EU)0.012 (μg/capita/day)
Maximised Survey-derived Daily Intakes (MSDI-USA)0.20 (μg/capita/day)
Modified Theoretical Added Maximum Daily Intake (mTAMDI)340 (μg/person/day)
Threshold of Concern1800 (μg/person/day)
Structure ClassI
baked goods2.00000
beverages(nonalcoholic)-
beverages(alcoholic)-
breakfast cereal0.20000
cheese0.40000
chewing gum-
condiments / relishes0.10000
confectionery froastings1.00000
egg products-
fats / oils0.10000
fish products0.20000
frozen dairy0.40000
fruit ices0.40000
gelatins / puddings-
granulated sugar-
gravies0.10000
hard candy-
imitation dairy-
instant coffee / tea-
jams / jellies-
meat products0.20000
milk products0.40000
nut products-
other grains0.20000
poultry0.20000
processed fruits0.40000
processed vegetables-
reconstituted vegetables-
seasonings / flavors0.10000
snack foods1.00000
soft candy-
soups0.10000
sugar substitutes-
sweet sauces-
Dairy products, excluding products of category 02.0 (01.0)0.40000
Fats and oils, and fat emulsions (type water-in-oil) (02.0)0.10000
Edible ices, including sherbet and sorbet (03.0)0.40000
Processed fruit (04.1)0.40000
Processed vegetables (incl. mushrooms & fungi, roots & tubers, pulses and legumes), and nuts & seeds (04.2)-
Confectionery (05.0)1.00000
Chewing gum (05.3)-
Cereals and cereal products, incl. flours & starches from roots & tubers, pulses & legumes, excluding bakery (06.0)0.20000
Bakery wares (07.0)2.00000
Meat and meat products, including poultry and game (08.0)0.20000
Fish and fish products, including molluscs, crustaceans and echinoderms (MCE) (09.0)0.20000
Eggs and egg products (10.0)-
Sweeteners, including honey (11.0)-
Salts, spices, soups, sauces, salads, protein products, etc. (12.0)0.10000
Foodstuffs intended for particular nutritional uses (13.0)0.20000
Non-alcoholic ("soft") beverages, excl. dairy products (14.1)-
Alcoholic beverages, incl. alcohol-free and low-alcoholic counterparts (14.2)1.00000
Ready-to-eat savouries (15.0)1.00000
Composite foods (e.g. casseroles, meat pies, mincemeat) - foods that could not be placed in categories 01.0 - 15.0 (16.0)0.20000

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Potential Uses

None Found

Natural Occurrence

apple fruit banana fruit barley seed cabbage leaf carrot root corn seed corn sprout elder black elder flower grape fruit juice soybean seed spinach leaf

Synonyms

aminoethane 1- aminoethane ethanamine mono ethyl amine N- ethyl amine ethylamine mono ethylamine Info: aliphatic and aromatic amines and amides PubMed: Nitrogen fertilisation increases biogenic amines and amino acid concentrations in Vitis vinifera var. Riesling musts and wines. PubMed: Sensing of amino acids by the gut-expressed taste receptor T1R1-T1R3 stimulates CCK secretion. PubMed: Kinetics of L-theanine uptake and metabolism in healthy participants are comparable after ingestion of L-theanine via capsules and green tea. PubMed: Levels of biogenic amines in retail market fermented meat products. PubMed: Effective separation of dopamine from bananas on 2-(3,4-dimethoxyphenyl)ethylamine imprinted polymer. PubMed: Antioxidant activity of Moringa oleifera tissue extracts. PubMed: Effects of amines and aminoalcohols on bovine intestine alkaline phosphatase activity. PubMed: Assessment of the genetic polymorphism and biogenic amine production of indigenous Oenococcus oeni strains isolated from Greek red wines. PubMed: Decreases in cocaine self-administration with dual inhibition of the dopamine transporter and σ receptors. PubMed: Gas chromatography-mass spectrometry assessment of amines in Port wine and grape juice after fast chloroformate extraction/derivatization. PubMed: Calcimimetics inhibit renal pathology in rodent nephronophthisis. PubMed: Purification and characterization of γ-glutamyltranspeptidase from Bacillus subtilis SK11.004. PubMed: Discovery and evaluation of pyrazolo[1,5-a]pyrimidines as neuropeptide Y1 receptor antagonists. PubMed: Development of efficient enzymatic production of theanine by γ-glutamyltranspeptidase from a newly isolated strain of Bacillus subtilis, SK11.004. PubMed: Rhodotorula taiwanensis sp. nov., a novel yeast species from a plant in Taiwan. PubMed: Development of a gas chromatography method for the estimation of alkylamines in foods. PubMed: Enzymatic synthesis of theanine from glutamic acid γ-methyl ester and ethylamine by immobilized Escherichia coli cells with γ-glutamyltranspeptidase activity. PubMed: Determination of biogenic amines in Korean traditional fermented soybean paste (Doenjang). PubMed: Reinforcing effects of sigma-receptor agonists in rats trained to self-administer cocaine. PubMed: A new ultra-pressure liquid chromatography method for the determination of biogenic amines in cheese. PubMed: Selective reduction of alcohol drinking in Sardinian alcohol-preferring rats by a sigma-1 receptor antagonist. PubMed: Biogenic amines in natural ciders. PubMed: Expression optimization and biochemical characterization of a recombinant gamma-glutamyltranspeptidase from Escherichia coli novablue. PubMed: Formation of biogenic amines throughout the industrial manufacture of red wine. PubMed: Acute blood pressure effects and chronic hypotensive action of calcimimetics in uremic rats. PubMed: Protection of originality of Tokaji Aszú: amines and organic acids in botrytized wines by high-performance liquid chromatography. PubMed: Interactions of organic compounds with wastewater dissolved organic matter: role of hydrophobic fractions. PubMed: Interrelationships among microbiological, physicochemical, and biochemical properties of Terrincho cheese, with emphasis on biogenic amines. PubMed: Purification and characterization of glutamine synthetase of Pseudomonas taetrolens Y-30: an enzyme usable for production of theanine by coupling with the alcoholic fermentation system of baker's yeast. PubMed: Theanine, gamma-glutamylethylamide, is metabolized by renal phosphate-independent glutaminase. PubMed: Content of biogenic amines in a Chardonnay wine obtained through spontaneous and inoculated fermentations. PubMed: Identification of yeasts present in sour fermented foods and fodders. PubMed: Deodorizing effects of tea catechins on amines and ammonia. PubMed: Effects of a methanolic extract and a hyperforin-enriched CO2 extract of Hypericum perforatum on alcohol intake in rats. PubMed: Ethylamine in human urine. PubMed: Volatile compounds thermally generated from S-propylcysteine and S-propylcysteine sulfoxide-aroma precursors of Allium vegetables. PubMed: Metabolism of theanine, gamma-glutamylethylamide, in rats. PubMed: Time-dependent changes of amino acids in the serum, liver, brain and urine of rats administered with theanine. PubMed: Sigma receptor ligands (+)-SKF10,047 and SA4503 improve dizocilpine-induced spatial memory deficits in rats. PubMed: Metabolites of N-ethylbenzamide, N,N-diethylbenzamide and related compounds detected in rat urine by NMR spectroscopy. PubMed: Nitrosatable amines and nitrosamide formation in natural stimulants: Cola acuminata, C. nitida and Garcinia cola. PubMed: Increased exposure to dietary amines and nitrate in a population at high risk of oesophageal and gastric cancer in Kashmir (India). PubMed: Quantitative determination of amines in wine by liquid chromatography. PubMed: Effects of dietary amines on the small intestine in calves fed soybean protein. PubMed: In-vivo activation of N-nitrosodiethanolamine and other n-nitroso-2-hydroxyalkylamines by alcohol dehydrogenase and sulfotransferase. PubMed: Abundance of dimethylamine in seafoods: possible implications in the incidence of human cancer. PubMed: High concentrations of dimethylamine and methylamine in squid and octopus and their implications in tumour aetiology. PubMed: Serum levels of dimenhydrinate. Determination by HPLC with UV detection after intake of dimenhydrinate in a coated chewing gum dragee. PubMed: Importance of dietary amines in meal-induced gastrin release. PubMed: Dose-response studies in carcinogenesis by nitroso-N-methyl-N-(2-phenyl)ethylamine in rats and the effects of deuterium substitution. PubMed: [On the problems in respect ot the formation of N-nitroso compound precursors when using alkylating agents in the fumigation of foodstuffs. I. Investigations of the formation of secondary amines by the action of ethylene oxide on primary amines and amino acids (author's transl)].