fusaric acid

picolinic acid, 5-butyl-

CAS: 536-69-6 C10 H13 N O2 MW: 179.21901000

Identification

Namefusaric acid
IUPAC5-butylpyridine-2-carboxylic acid
CAS Number536-69-6
EINECS208-643-0
FDA UNIIJWJ963070N
Molecular FormulaC10 H13 N O2
Molecular Weight179.21901000
MDL NumberMFCD00006298
Nikkaji NumberJ12.987I
Beilstein0125804

Regulatory

Physical Properties

Assay 95.00 to 100.00
Food Chemicals Codex Listed No
Melting Point 97.00 °C. @ 760.00 mm Hg
Boiling Point 329.20 °C. @ 760.00 mm Hg (est)
Flash Point 307.00 °F. TCC ( 152.90 °C. ) (est)
logP (o/w) 1.960 (est)
Soluble in water, 271.2 mg/L @ 25 °C (est)

No sensory data available

Safety Information

Preferred SDSView
Oral/Parenteral Toxicityintravenous-dog LD50 180 mg/kg
Dermal Toxicitysubcutaneous-mouse LD50 140 mg/kg
Inhalation ToxicityNot determined

GHS Classification

['GHS Classification in accordance with 29 CFR 1910 (OSHA HCS)', 'GHS Label elements, including precautionary statements', 'GASTROINTESTINAL: NAUSEA OR VOMITING\nVASCULAR: BP LOWERING NOT CHARACTERIZED IN AUTONOMIC SECTION', 'VASCULAR: BP LOWERING NOT CHARACTERIZED IN AUTONOMIC SECTION', 'BEHAVIORAL: SOMNOLENCE (GENERAL DEPRESSED ACTIVITY)\nVASCULAR: BP LOWERING NOT CHARACTERIZED IN AUTONOMIC SECTION', 'VASCULAR: BP LOWERING NOT CHARACTERIZED IN AUTONOMIC SECTION\nBEHAVIORAL: SOMNOLENCE (GENERAL DEPRESSED ACTIVITY)']

Safety in Use

Categorynatural substances and extractives
Recommendation for fusaric acid usage levels up tonot for fragrance use.
Recommendation for fusaric acid flavor usage levels up tonot for flavor use.

No supplier data available

Potential Uses

None Found

Natural Occurrence

trichoderma atroviride PMC

Synonyms

5- butyl pyridine-3-carboxylic acid 5- butyl-2-pyridinecarboxylic acid 5- butylpicolinic acid 5- butylpyridine-2-carboxylic acid 5-N- butylpyridine-2-carboxylic acid fusarinic acid picolinic acid, 5-butyl- picolinic acid, 5-butyl- (8CI) 2- pyridinecarboxylic acid, 5-butyl- PubMed: Native cell-death genes as candidates for developing wilt resistance in transgenic banana plants. PubMed: Fusarium verticillioides SGE1 is required for full virulence and regulates expression of protein effector and secondary metabolite biosynthetic genes. PubMed: Characterization of the fusaric acid gene cluster in Fusarium fujikuroi. PubMed: The effects of different yeast extracts on secondary metabolite production in Fusarium. PubMed: Determination of fusaric acid in maize using molecularly imprinted SPE clean-up. PubMed: Contamination of bananas with beauvericin and fusaric acid produced by Fusarium oxysporum f. sp. cubense. PubMed: Mycotoxins in corn and wheat silage in Israel. PubMed: Masked mycotoxins: a review. PubMed: Identification of gene clusters associated with fusaric acid, fusarin, and perithecial pigment production in Fusarium verticillioides. PubMed: Single-kernel analysis of fumonisins and other fungal metabolites in maize from South African subsistence farmers. PubMed: Ultrahigh-performance liquid chromatographic-tandem mass spectrometric multimycotoxin method for quantitating 26 mycotoxins in maize silage. PubMed: Fusarium species (section Liseola) occurrence and natural incidence of beauvericin, fusaproliferin and fumonisins in maize hybrids harvested in Mexico. PubMed: Nuclear magnetic resonance (NMR) studies on the biosynthesis of fusaric acid from Fusarium oxysporum f. sp. vasinfectum. PubMed: Feed contaminated with Fusarium toxins alter lymphocyte proliferation and apoptosis in primiparous sows during the perinatal period. PubMed: Identification, mycotoxin risk and pathogenicity of Fusarium species associated with fig endosepsis in Apulia, Italy. PubMed: Effects of a deoxynivalenol-contaminated diet on the reproductive performance and immunoglobulin concentrations in pigs. PubMed: [Study of specificity of fungistatic effect of trichothecene mycotoxins]. PubMed: Bikaverin and fusaric acid from Fusarium oxysporum show antioomycete activity against Phytophthora infestans. PubMed: Effects of foodborne Fusarium mycotoxins with and without a polymeric glucomannan mycotoxin adsorbent on food intake and nutrient digestibility, body weight, and physical and clinicopathologic variables of mature dogs. PubMed: Mycotoxins and the pet food industry: toxicological evidence and risk assessment. PubMed: Mycotoxin producing Fusarium species associated with plant disease on potato, wheat, corn and animal diseases in northwest Iran. PubMed: Growth-inhibiting effects of concentrations of fusaric acid on the growth of Bacillus mojavensis and other biocontrol Bacillus species. PubMed: Effects of feeding blends of grains naturally contaminated with Fusarium mycotoxins on growth and immunological parameters of broiler chickens. PubMed: Effects of feeding a blend of grains naturally contaminated with Fusarium mycotoxins on feed intake, serum chemistry, and hematology of horses, and the efficacy of a polymeric glucomannan mycotoxin adsorbent. PubMed: Antioxidant nutrients and mycotoxins. PubMed: Effects of feeding blends of grains naturally contaminated with Fusarium mycotoxins on production and metabolism in broilers. PubMed: Intracerebroventricular injection of fusaric acid attenuates the anorexia by glucagon-like peptide-1 in the neonatal chick. PubMed: Degradation and transformation of a potential natural herbicide in three soils. PubMed: Fusaric acid and modification of the subchronic toxicity to rats of fumonisins in F. moniliforme culture material. PubMed: Biological detoxification of fungal toxins and its use in plant breeding, feed and food production. PubMed: Induction of food intake by a noradrenergic system using clonidine and fusaric acid in the neonatal chick. PubMed: Production of fusaric acid by Fusarium species. PubMed: Effects of mycotoxins on cytokine production and proliferation in EL-4 thymoma cells. PubMed: Neuropharmacological studies on Fusarium toxins--II: Total toxin extract from F. oxysporum. PubMed: Fusaric acid in Fusarium moniliforme cultures, corn, and feeds toxic to livestock and the neurochemical effects in the brain and pineal gland of rats. PubMed: Decreased cell-mediated immunity and lack of skeletal problems in broiler chickens consuming diets amended with fusaric acid. PubMed: Taxonomy and biology of Fusarium moniliforme. PubMed: Biological and chemical characterization of metabolites of Fusarium moniliforme isolates. PubMed: Dopamine-beta-hydroxylase inhibitors, feeding and locomotor activity: reinstatement of feeding following central norepinephrine. PubMed: Mouse bioassay for Fusarium metabolites: rejection or acceptance when dissolved in drinking water.