fusaric acid
picolinic acid, 5-butyl-
Identification
| Name | fusaric acid |
| IUPAC | 5-butylpyridine-2-carboxylic acid |
| CAS Number | 536-69-6 |
| EINECS | 208-643-0 |
| FDA UNII | JWJ963070N |
| Molecular Formula | C10 H13 N O2 |
| Molecular Weight | 179.21901000 |
| MDL Number | MFCD00006298 |
| Nikkaji Number | J12.987I |
| Beilstein | 0125804 |
Regulatory
Physical Properties
| Assay | 95.00 to 100.00 |
| Food Chemicals Codex Listed | No |
| Melting Point | 97.00 °C. @ 760.00 mm Hg |
| Boiling Point | 329.20 °C. @ 760.00 mm Hg (est) |
| Flash Point | 307.00 °F. TCC ( 152.90 °C. ) (est) |
| logP (o/w) | 1.960 (est) |
| Soluble in | water, 271.2 mg/L @ 25 °C (est) |
No sensory data available
Safety Information
| Preferred SDS | View |
| Oral/Parenteral Toxicity | intravenous-dog LD50 180 mg/kg |
| Dermal Toxicity | subcutaneous-mouse LD50 140 mg/kg |
| Inhalation Toxicity | Not determined |
GHS Classification
['GHS Classification in accordance with 29 CFR 1910 (OSHA HCS)', 'GHS Label elements, including precautionary statements', 'GASTROINTESTINAL: NAUSEA OR VOMITING\nVASCULAR: BP LOWERING NOT CHARACTERIZED IN AUTONOMIC SECTION', 'VASCULAR: BP LOWERING NOT CHARACTERIZED IN AUTONOMIC SECTION', 'BEHAVIORAL: SOMNOLENCE (GENERAL DEPRESSED ACTIVITY)\nVASCULAR: BP LOWERING NOT CHARACTERIZED IN AUTONOMIC SECTION', 'VASCULAR: BP LOWERING NOT CHARACTERIZED IN AUTONOMIC SECTION\nBEHAVIORAL: SOMNOLENCE (GENERAL DEPRESSED ACTIVITY)']
Safety in Use
| Category | natural substances and extractives |
| Recommendation for fusaric acid usage levels up to | not for fragrance use. |
| Recommendation for fusaric acid flavor usage levels up to | not for flavor use. |
No supplier data available
Potential Uses
Natural Occurrence
Synonyms
5-
butyl pyridine-3-carboxylic acid
5-
butyl-2-pyridinecarboxylic acid
5-
butylpicolinic acid
5-
butylpyridine-2-carboxylic acid
5-N-
butylpyridine-2-carboxylic acid
fusarinic acid
picolinic acid, 5-butyl-
picolinic acid, 5-butyl- (8CI)
2-
pyridinecarboxylic acid, 5-butyl-
PubMed:
Native cell-death genes as candidates for developing wilt resistance in transgenic banana plants.
PubMed:
Fusarium verticillioides SGE1 is required for full virulence and regulates expression of protein effector and secondary metabolite biosynthetic genes.
PubMed:
Characterization of the fusaric acid gene cluster in Fusarium fujikuroi.
PubMed:
The effects of different yeast extracts on secondary metabolite production in Fusarium.
PubMed:
Determination of fusaric acid in maize using molecularly imprinted SPE clean-up.
PubMed:
Contamination of bananas with beauvericin and fusaric acid produced by Fusarium oxysporum f. sp. cubense.
PubMed:
Mycotoxins in corn and wheat silage in Israel.
PubMed:
Masked mycotoxins: a review.
PubMed:
Identification of gene clusters associated with fusaric acid, fusarin, and perithecial pigment production in Fusarium verticillioides.
PubMed:
Single-kernel analysis of fumonisins and other fungal metabolites in maize from South African subsistence farmers.
PubMed:
Ultrahigh-performance liquid chromatographic-tandem mass spectrometric multimycotoxin method for quantitating 26 mycotoxins in maize silage.
PubMed:
Fusarium species (section Liseola) occurrence and natural incidence of beauvericin, fusaproliferin and fumonisins in maize hybrids harvested in Mexico.
PubMed:
Nuclear magnetic resonance (NMR) studies on the biosynthesis of fusaric acid from Fusarium oxysporum f. sp. vasinfectum.
PubMed:
Feed contaminated with Fusarium toxins alter lymphocyte proliferation and apoptosis in primiparous sows during the perinatal period.
PubMed:
Identification, mycotoxin risk and pathogenicity of Fusarium species associated with fig endosepsis in Apulia, Italy.
PubMed:
Effects of a deoxynivalenol-contaminated diet on the reproductive performance and immunoglobulin concentrations in pigs.
PubMed:
[Study of specificity of fungistatic effect of trichothecene mycotoxins].
PubMed:
Bikaverin and fusaric acid from Fusarium oxysporum show antioomycete activity against Phytophthora infestans.
PubMed:
Effects of foodborne Fusarium mycotoxins with and without a polymeric glucomannan mycotoxin adsorbent on food intake and nutrient digestibility, body weight, and physical and clinicopathologic variables of mature dogs.
PubMed:
Mycotoxins and the pet food industry: toxicological evidence and risk assessment.
PubMed:
Mycotoxin producing Fusarium species associated with plant disease on potato, wheat, corn and animal diseases in northwest Iran.
PubMed:
Growth-inhibiting effects of concentrations of fusaric acid on the growth of Bacillus mojavensis and other biocontrol Bacillus species.
PubMed:
Effects of feeding blends of grains naturally contaminated with Fusarium mycotoxins on growth and immunological parameters of broiler chickens.
PubMed:
Effects of feeding a blend of grains naturally contaminated with Fusarium mycotoxins on feed intake, serum chemistry, and hematology of horses, and the efficacy of a polymeric glucomannan mycotoxin adsorbent.
PubMed:
Antioxidant nutrients and mycotoxins.
PubMed:
Effects of feeding blends of grains naturally contaminated with Fusarium mycotoxins on production and metabolism in broilers.
PubMed:
Intracerebroventricular injection of fusaric acid attenuates the anorexia by glucagon-like peptide-1 in the neonatal chick.
PubMed:
Degradation and transformation of a potential natural herbicide in three soils.
PubMed:
Fusaric acid and modification of the subchronic toxicity to rats of fumonisins in F. moniliforme culture material.
PubMed:
Biological detoxification of fungal toxins and its use in plant breeding, feed and food production.
PubMed:
Induction of food intake by a noradrenergic system using clonidine and fusaric acid in the neonatal chick.
PubMed:
Production of fusaric acid by Fusarium species.
PubMed:
Effects of mycotoxins on cytokine production and proliferation in EL-4 thymoma cells.
PubMed:
Neuropharmacological studies on Fusarium toxins--II: Total toxin extract from F. oxysporum.
PubMed:
Fusaric acid in Fusarium moniliforme cultures, corn, and feeds toxic to livestock and the neurochemical effects in the brain and pineal gland of rats.
PubMed:
Decreased cell-mediated immunity and lack of skeletal problems in broiler chickens consuming diets amended with fusaric acid.
PubMed:
Taxonomy and biology of Fusarium moniliforme.
PubMed:
Biological and chemical characterization of metabolites of Fusarium moniliforme isolates.
PubMed:
Dopamine-beta-hydroxylase inhibitors, feeding and locomotor activity: reinstatement of feeding following central norepinephrine.
PubMed:
Mouse bioassay for Fusarium metabolites: rejection or acceptance when dissolved in drinking water.