gamma-laevo-glutamyl-laevo-glutamic acid
L-g-glutamyl-L-glutamic acid
Identification
| Name | gamma-laevo-glutamyl-laevo-glutamic acid |
| IUPAC | (2S)-2-[[(4S)-4-amino-4-carboxybutanoyl]amino]pentanedioic acid |
| CAS Number | 1116-22-9 |
| EINECS | 214-233-2 |
| FDA UNII | 6018KCN7X2 |
| Molecular Formula | C10 H16 N2 O7 |
| Molecular Weight | 276.24592000 |
| Nikkaji Number | J203.335F |
Regulatory
Physical Properties
| Assay | 95.00 to 100.00 |
| Food Chemicals Codex Listed | No |
| Boiling Point | 664.08 °C. @ 760.00 mm Hg (est) |
| Flash Point | 672.00 °F. TCC ( 355.40 °C. ) (est) |
| logP (o/w) | -2.603 (est) |
| Soluble in | water, 8.444e+004 mg/L @ 25 °C (est) |
No sensory data available
Safety Information
| Oral/Parenteral Toxicity | Not determined |
| Dermal Toxicity | Not determined |
| Inhalation Toxicity | Not determined |
GHS Classification
['GHS Classification in accordance with 29 CFR 1910 (OSHA HCS)', 'GHS Label elements, including precautionary statements']
Safety in Use
| Category | natural substances and extractives |
| Recommendation for gamma-laevo-glutamyl-laevo-glutamic acid usage levels up to | not for fragrance use. |
| Recommendation for gamma-laevo-glutamyl-laevo-glutamic acid flavor usage levels up to | not for flavor use. |
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Potential Uses
Natural Occurrence
Synonyms
(2S)-2-[[(4S)-4-
amino-4-carboxybutanoyl]amino]pentanedioic acid
g-L-
glutamyl-L-glutamic acid
L-g-
glutamyl-L-glutamic acid
N-gamma-l-
glutamyl-L-glutamic acid
PubMed:
Mass spectrometric and kinetic studies on slow progression of papain-catalyzed polymerization of L-glutamic acid diethyl ester.
PubMed:
Monoclonal anti-dipeptide antibodies cross-react with detyrosinated and glutamylated forms of tubulins.
PubMed:
Monoclonal antibody specific for carbodiimide-fixed glutamate: immunocytochemical localization in the rat CNS.
PubMed:
The effects of carbamazepine and valproate on folate metabolism in man.
PubMed:
Influx of two dipeptides, glycylsarcosine and L-glutamyl-L-glutamic acid, into hamster jejunum in vitro.
PubMed:
Proposed structure for coenzyme F420 from Methanobacterium.
PubMed:
Purification and properties of the dihydrofolate synthetase from Serratia indica.
PubMed:
[Pterin chemistry. An unequivocal synthesis of pteroyl-gamma-L-glutamyl-gamma-L-glutamyl-L-glutamic acid].
PubMed:
Depression of jejunal dipeptide transport by pyridoxine deficiency in the rat.
PubMed:
Studies on a wide-spectrum intestinal dipeptide uptake system in the monkey and in the human.
PubMed:
[Pterin chemistry. 45. A new and clear synthesis of isomer-free pteroyl-gamma-L-glutamyl-L-glutamic acid].
PubMed:
[Study on gamma-blutamyl peptides. I. Isolation and identification of gamma-L-glutamyl-L-glutamic acid and gamma-L-glutamyl-L-glutamine from the bovine brain].
PubMed:
ISOLATION OF GAMMA-L-GLUTAMYL-L-GLUTAMIC ACID AND GAMMA-L-GLUTAMYL-L-GLUTAMINE FROM BOVINE BRAIN.