gamma-laevo-glutamyl-laevo-glutamic acid

L-g-glutamyl-L-glutamic acid

CAS: 1116-22-9 C10 H16 N2 O7 MW: 276.24592000

Identification

Namegamma-laevo-glutamyl-laevo-glutamic acid
IUPAC(2S)-2-[[(4S)-4-amino-4-carboxybutanoyl]amino]pentanedioic acid
CAS Number1116-22-9
EINECS214-233-2
FDA UNII6018KCN7X2
Molecular FormulaC10 H16 N2 O7
Molecular Weight276.24592000
Nikkaji NumberJ203.335F

Regulatory

Physical Properties

Assay 95.00 to 100.00
Food Chemicals Codex Listed No
Boiling Point 664.08 °C. @ 760.00 mm Hg (est)
Flash Point 672.00 °F. TCC ( 355.40 °C. ) (est)
logP (o/w) -2.603 (est)
Soluble in water, 8.444e+004 mg/L @ 25 °C (est)

No sensory data available

Safety Information

Oral/Parenteral ToxicityNot determined
Dermal ToxicityNot determined
Inhalation ToxicityNot determined

GHS Classification

['GHS Classification in accordance with 29 CFR 1910 (OSHA HCS)', 'GHS Label elements, including precautionary statements']

Safety in Use

Categorynatural substances and extractives
Recommendation for gamma-laevo-glutamyl-laevo-glutamic acid usage levels up tonot for fragrance use.
Recommendation for gamma-laevo-glutamyl-laevo-glutamic acid flavor usage levels up tonot for flavor use.

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Potential Uses

None Found

Natural Occurrence

found in nature

Synonyms

(2S)-2-[[(4S)-4- amino-4-carboxybutanoyl]amino]pentanedioic acid g-L- glutamyl-L-glutamic acid L-g- glutamyl-L-glutamic acid N-gamma-l- glutamyl-L-glutamic acid PubMed: Mass spectrometric and kinetic studies on slow progression of papain-catalyzed polymerization of L-glutamic acid diethyl ester. PubMed: Monoclonal anti-dipeptide antibodies cross-react with detyrosinated and glutamylated forms of tubulins. PubMed: Monoclonal antibody specific for carbodiimide-fixed glutamate: immunocytochemical localization in the rat CNS. PubMed: The effects of carbamazepine and valproate on folate metabolism in man. PubMed: Influx of two dipeptides, glycylsarcosine and L-glutamyl-L-glutamic acid, into hamster jejunum in vitro. PubMed: Proposed structure for coenzyme F420 from Methanobacterium. PubMed: Purification and properties of the dihydrofolate synthetase from Serratia indica. PubMed: [Pterin chemistry. An unequivocal synthesis of pteroyl-gamma-L-glutamyl-gamma-L-glutamyl-L-glutamic acid]. PubMed: Depression of jejunal dipeptide transport by pyridoxine deficiency in the rat. PubMed: Studies on a wide-spectrum intestinal dipeptide uptake system in the monkey and in the human. PubMed: [Pterin chemistry. 45. A new and clear synthesis of isomer-free pteroyl-gamma-L-glutamyl-L-glutamic acid]. PubMed: [Study on gamma-blutamyl peptides. I. Isolation and identification of gamma-L-glutamyl-L-glutamic acid and gamma-L-glutamyl-L-glutamine from the bovine brain]. PubMed: ISOLATION OF GAMMA-L-GLUTAMYL-L-GLUTAMIC ACID AND GAMMA-L-GLUTAMYL-L-GLUTAMINE FROM BOVINE BRAIN.