guanidine HCl

guanidine, hydrochloride (1:1)

CAS: 50-01-1 C H6 Cl N3 MW: 95.53182000

Identification

Nameguanidine HCl
IUPACguanidine;hydrochloride
CAS Number50-01-1
EINECS200-002-3
FDA UNII3YQC9ZY4YB
Molecular FormulaC H6 Cl N3
Molecular Weight95.53182000
MDL NumberMFCD00013026
Beilstein3591990

Regulatory

Physical Properties

Assay 95.00 to 100.00
Food Chemicals Codex Listed No
Melting Point 182.30 °C. @ 760.00 mm Hg
Flash Point 32.00 °F. TCC ( 0.00 °C. ) (est)
Soluble in water, 1e+006 mg/L @ 25 °C (est)

Cosmetic Information

CosIngcosmetic data
Cosmetic Usesbuffering agents

No sensory data available

Safety Information

Preferred SDSView
Oral/Parenteral Toxicityintraarterial-guinea pig LDLo 500 mg/kg
Dermal Toxicitysubcutaneous-dog LDLo 200 mg/kg
Inhalation ToxicityNot determined

GHS Classification

['GHS Classification in accordance with 29 CFR 1910 (OSHA HCS)', 'GHS Label elements, including precautionary statements', 'BEHAVIORAL: MUSCLE CONTRACTION OR SPASTICITY)\nBEHAVIORAL: ALTERED SLEEP TIME (INCLUDING CHANGE IN RIGHTING REFLEX)\nBEHAVIORAL: IRRITABILITY', 'GASTROINTESTINAL: "HYPERMOTILITY, DIARRHEA"\nBEHAVIORAL: EXCITEMENT\nBEHAVIORAL: ALTERED SLEEP TIME (INCLUDING CHANGE IN RIGHTING REFLEX)']

Safety in Use

Categorybuffering agents
Recommendation for guanidine HCl usage levels up tonot for fragrance use.
Recommendation for guanidine HCl flavor usage levels up tonot for flavor use.

BOC Sciences

Best of Chemicals Supplier

Quality supplier of research chemicals and biochemicals including inhibitors, building blocks, GMP Products, impurities and metabolites, APIs for Veterinary, Natural Compounds, ADCs, Stem Cell Molecul...

View All Website 1-631-485-4226 account@bocsci.com

Glentham Life Sciences Ltd

The Chemical, Biochemical & Research Essentials Supplier

Glentham Life Sciences is a supplier of fine chemicals and raw materials with warehousing, laboratories and packaging facilities in the UK.

View All Website +44 (0) 1225 667798 info@glentham.com

Potential Uses

None Found

Natural Occurrence

not found in nature

Synonyms

amino(imino)methanaminium chloride diaminomethaniminium chloride guanidine hydrochloride guanidine hydrochloride (1:1) guanidine monohydrochloride guanidine, hydrochloride (1:1) guanidine;hydrochloride guanidinium hydrochloride PubMed: Caseins from bovine colostrum and milk strongly bind piscidin-1, an antimicrobial peptide from fish. PubMed: Synergistic effects of guanidine-grafted CMC on enhancing antimicrobial activity and dry strength of paper. PubMed: Lipopolysaccharide induced conversion of recombinant prion protein. PubMed: Biochemical and atomic force microscopic characterization of salmon nasal cartilage proteoglycan. PubMed: Aggregation and adhesion properties of 22 Lactobacillus strains. PubMed: Enhanced inhibition of foot-and-mouth disease virus by combinations of porcine interferon-α and antiviral agents. PubMed: Akwaton, polyhexamethylene-guanidine hydrochloride-based sporicidal disinfectant: a novel tool to fight bacterial spores and nosocomial infections. PubMed: Antimicrobial activities of polyhexamethylene guanidine hydrochloride-based disinfectant against fungi isolated from cocoa beans and reference strains of bacteria. PubMed: Comparison of three DNA extraction methods for feed products and four amplification methods for the 5'-junction fragment of Roundup Ready soybean. PubMed: Fluorescence studies on the stability, flexibility and substrate-induced conformational changes of acetate kinases from psychrophilic and mesophilic bacteria. PubMed: LogSpin: a simple, economical and fast method for RNA isolation from infected or healthy plants and other eukaryotic tissues. PubMed: Biophysical studies of an NAD(P)(+)-dependent aldehyde dehydrogenase from Bacillus licheniformis. PubMed: Deactivation of soybean agglutinin by enzymatic and other physical treatments. PubMed: Conformational and thermal properties of phaseolin, the major storage protein of red kidney bean (Phaseolus vulgaris L.). PubMed: Technical note: comparing calibration methods for determination of protein in goat milk by ultraviolet spectroscopy. PubMed: Characterization of functional intermediates of endoglucanase from Aspergillus aculeatus during urea and guanidine hydrochloride unfolding. PubMed: Development of an optimized ELISA and a sample preparation method for the detection of beta-lactoglobulin traces in baby foods. PubMed: Interaction of chaperone alpha-crystallin with unfolded state of alpha-amylase: Implications for reconstitution of the active enzyme. PubMed: Identification and characterization of ambroxol as an enzyme enhancement agent for Gaucher disease. PubMed: Methyl alpha-D-glucopyranoside enhances the enzymatic activity of recombinant beta-galactosidase inclusion bodies in the araBAD promoter system of Escherichia coli. PubMed: Moisture-induced aggregation of whey proteins in a protein/buffer model system. PubMed: Isolation of surface (S) layer protein carrying Lactobacillus species from porcine intestine and faeces and characterization of their adhesion properties to different host tissues. PubMed: Effect of ionic detergents, nonionic detergents, and chaotropic agents on polyphenol oxidase activity from dormant saffron (Crocus sativus L.) corms. PubMed: Multiplexed detection of mycotoxins in foods with a regenerable array. PubMed: Refolding and activation of human prorenin expressed in Escherichia coli: application of recombinant human renin for inhibitor screening. PubMed: Conformational stability of 17 beta-hydroxysteroid dehydrogenase from the fungus Cochliobolus lunatus. PubMed: Bioanalysis and pharmacokinetics of chitosan ester in rabbit serum by HPLC with postcolumn fluorescence derivatization. PubMed: Dimerization specificity of adult and neonatal chicken skeletal muscle myosin heavy chain rods. PubMed: Assay of bone morphogenetic protein-2, -4, and -7 in human demineralized bone matrix. PubMed: Modification of beta-lactoglobulin by oligofructose: impact on protein adsorption at the air-water interface. PubMed: Rice allergenic proteins, 14-16 kDa albumin and alpha-globulin, remain insoluble in rice grains recovered from rice miso (rice-containing fermented soybean paste). PubMed: Development of a general procedure for complete extraction of gliadins for heat processed and unheated foods. PubMed: The production of recombinant APRP, an alkaline protease derived from Bacillus pumilus TYO-67, by in vitro refolding of pro-enzyme fixed on a solid surface. PubMed: Study on Escherichia coli alkaline phosphatase conformation by phosphorimetry in the presence of denaturant. PubMed: Chemical processing as a tool to generate ovalbumin variants with changed stability. PubMed: Reversible denaturation behavior of immobilized glucose oxidase. PubMed: A tetrodotoxin-binding protein in the hemolymph of shore crab Hemigrapsus sanguineus: purification and properties. PubMed: Reductive unfolding and oxidative refolding of a Bowman-Birk inhibitor from horsegram seeds (Dolichos biflorus): evidence for "hyperreactive" disulfide bonds and rate-limiting nature of disulfide isomerization in folding. PubMed: The folding of alpha-1-proteinase inhibitor: kinetic vs equilibrium control. PubMed: Functional implications of the beta-helical protein fold: differences in chemical and thermal stabilities of Erwinia chrysanthemi EC16 pectate lyases B, C, and E. PubMed: Structural and functional consequences of removal of the interdomain disulfide bridge from the isolated C-lobe of ovotransferrin. PubMed: Unfolding of multimeric proteins in presence of denaturants. A case study of helianthinin from Helianthus annuus L. PubMed: Determination of molecular weight of agars and effect of the molecular weight on the glass transition. PubMed: Reusability of avidin-biotinylated immunoglobulin Y columns in immunoaffinity chromatography. PubMed: Isolation and characterization of proteoglycans from growing antlers of wapiti (Cervus elaphus). PubMed: Quantitative analysis of Gly m Bd 28K in soybean products by a sandwich enzyme-linked immunosorbent assay. PubMed: Effects of roxarsone and monensin on digital flexoral tendons of broiler chickens. PubMed: Assessment of the protein quality of the smooth muscle myofibrillar and connective tissue proteins of chicken gizzard. PubMed: Status of Cys residues in the covalent structure of botulinum neurotoxin types A, B, and E. PubMed: High-level expression of bovine beta-lactoglobulin in Pichia pastoris and characterization of its physical properties. PubMed: Chemical and thermal stability of ferulic acid esterase-III from Aspergillus niger. PubMed: Seminested RT-PCR systems for small round structured viruses and detection of enteric viruses in seafood. PubMed: The detection of kinetic intermediates during the unfolding of lipoxygenase-1 by urea or guanidine hydrochloride. PubMed: Physical, biochemical, and immunological characterization of a thermostable amidase from Klebsiella pneumoniae NCTR 1. PubMed: Aggregated form of dextransucrases from Leuconostoc mesenteroides NRRL B-512F and its constitutive mutant. PubMed: Role of disulfide linkages in structure and activity of proteinase inhibitor from horsegram (Dolichos biflorus). PubMed: A comparison of methods for determining total body protein. PubMed: Interaction of guanidine hydrochloride and guanidine thiocyanate with wheat germ lipase. PubMed: Retrospective study of 108 cases of botulism in Poitiers, France. PubMed: Thermostable variants of bovine beta-lactoglobulin. PubMed: In vitro self-assembly of the S layer subunits from Clostridium difficile GAI 0714 into tetragonal arrays. PubMed: Isolation and renaturation of bio-active proteins expressed in Escherichia coli as inclusion bodies. PubMed: O-glycosylation and stability. Unfolding of glucoamylase induced by heat and guanidine hydrochloride. PubMed: Active papain renatured and processed from insoluble recombinant propapain expressed in Escherichia coli. PubMed: Molecular stability of chicken and rabbit immunoglobulin G. PubMed: Determination of profiles of non-collagenous proteins from rat bones by sodium dodecyl sulfate high-performance liquid chromatography. PubMed: Nature of the tryptic/chymotryptic inhibitor from horsegram (Dolichos biflorus). PubMed: Development and characterization of a monoclonal antibody specific for Listeria monocytogenes and Listeria innocua. PubMed: A kinetic and equilibrium study of the denaturation of aspartic proteinases from the fungi, Endothia parasitica and Mucor miehei. PubMed: Denaturation behavior of phaseolin in urea, guanidine hydrochloride, and sodium dodecyl sulfate solutions. PubMed: Competing solvent effects of polyols and guanidine hydrochloride on protein stability. PubMed: Expression of recombinant bovine beta-lactoglobulin in Escherichia coli. PubMed: Freezing denaturation of ovalbumin at acid pH. PubMed: The binding of 3H-labelled androgen-receptor complexes to hypothalamic chromatin of neonatal mice: effect of sex and androgenization. PubMed: Single site proteolysis in silkworm antitrypsin causes structural changes in behavior against denaturing reagents. PubMed: Influence of glycosylation on the oligomeric structure of yeast acid phosphatase. PubMed: Isolation and characterization of cytoplasmic fibrils from treponemes. PubMed: Characterization and reassembly of a regular array in the cell wall of Clostridium difficile GAI 4131. PubMed: Manganese rickets. A biochemical and stereologic study with special reference to the effect of phosphate. PubMed: Isolation and characterization of rat intestinal polyribosomes and RNA during absorption of fat. Increased translation in vitro of apo-AIV. PubMed: Species identification of cooked meats by enzyme-staining of isoelectricfocusing gels. PubMed: Wheat Storage Proteins : ISOLATION AND CHARACTERIZATION OF THE GLIADIN MESSENGER RNAs. PubMed: Absorption, excretion, and metabolism of 1,3-bis(p-chlorobenzylideneamino)guanidine hydrochloride (Robenz robenidine hydrochloride) in the chicken. PubMed: Absorption, excretion, and metabolism of robenz, robenidine hydrochloride (1,3-bis(p-chlorobenzylideneamino)guanidine hydrochloride), in the rat.