hesperidin methyl chalcone
2-propen-1-one, 1-[4-[[6-O-(6-deoxy-a-L-mannopyranosyl)-β-D-glucopyranosyl]oxy]-2-hydroxy-6-methoxyphenyl]-3-(3-hydroxy-4-methoxyphenyl)-, (2E)-
Identification
| Name | hesperidin methyl chalcone |
| CAS Number | 24292-52-2 |
| EINECS | 246-128-2 |
| FDA UNII | 4T2GVA922X |
| Molecular Formula | C29 H36 O15 |
| Molecular Weight | 624.59392000 |
| MDL Number | MFCD00010438 |
Regulatory
Physical Properties
| Assay | 95.00 to 100.00 |
| Food Chemicals Codex Listed | No |
| Boiling Point | 952.97 °C. @ 760.00 mm Hg (est) |
| Flash Point | 589.00 °F. TCC ( 309.50 °C. ) (est) |
| logP (o/w) | 0.267 (est) |
| Soluble in | water, 692.9 mg/L @ 25 °C (est) |
Cosmetic Information
| CosIng | cosmetic data |
| Cosmetic Uses | antioxidants |
No sensory data available
Safety Information
| Preferred SDS | View |
| Oral/Parenteral Toxicity | Not determined |
| Dermal Toxicity | Not determined |
| Inhalation Toxicity | Not determined |
GHS Classification
['GHS Classification in accordance with 29 CFR 1910 (OSHA HCS)', 'GHS Label elements, including precautionary statements']
Safety in Use
| Category | antioxidants |
| Recommendation for hesperidin methyl chalcone usage levels up to | not for fragrance use. |
| Recommendation for hesperidin methyl chalcone flavor usage levels up to | not for flavor use. |
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Potential Uses
Natural Occurrence
Synonyms
hesperidin methylchalcone
3-
hydroxy-4-[(2E)-3-(3-hydroxy-4-methoxyphenyl)-2-propenoyl]-5-methoxyphenyl 6-O-(6-deoxy-a-L-mannopyranosyl)-β-D-glucopyranoside
2-
propen-1-one, 1-[4-[[6-O-(6-deoxy-a-L-mannopyranosyl)-β-D-glucopyranosyl]oxy]-2-hydroxy-6-methoxyphenyl]-3-(3-hydroxy-4-methoxyphenyl)-, (2E)-
PubMed:
Quality of life improvement in Latin American patients suffering from chronic venous disorder using a combination of Ruscus aculeatus and hesperidin methyl-chalcone and ascorbic acid (quality study).
PubMed:
Assessment of quality of life in Mexican patients suffering from chronic venous disorder - impact of oral Ruscus aculeatus-hesperidin-methyl-chalcone-ascorbic acid treatment - 'QUALITY Study'.
PubMed:
Meta-analysis of clinical trials of Cyclo 3 Fort in the treatment of chronic venous insufficiency.
PubMed:
An open-label, randomized multicenter study comparing the efficacy and safety of Cyclo 3 Fort versus hydroxyethyl rutoside in chronic venous lymphatic insufficiency.
PubMed:
An open-label, randomised multicentre study comparing the efficacy and safety of CYCLO 3 FORT versus hydroxyethyl rutoside in chronic venous lymphatic insufficiency.
PubMed:
Treatment of secondary lymphedema of the upper limb with CYCLO 3 FORT.
PubMed:
A thin-layer chromatographic-fluorometric method for quantitative analysis of hesperidin methyl chalcone in parmaceuticals.
PubMed:
Effect of hesperidin-methyl-chalcone on capillary resistance in the internal organs of the guinea pig and the rat.
PubMed:
The effect of hesperidin methyl chalcone on the nervous control of the nictitating membrane.
PubMed:
Effect of hesperidin methyl chalcone, vitamin P, on diabetic retinopathy.
PubMed:
Administration of massive doses of vitamin P hesperidin methyl chalcone.