histamine

imidazole, 4-(2-aminoethyl)-

CAS: 51-45-6 C5 H9 N3 MW: 111.14773000

Identification

Namehistamine
IUPAC2-(1H-imidazol-5-yl)ethanamine
CAS Number51-45-6
EINECS200-100-6
FDA UNII820484N8I3
Molecular FormulaC5 H9 N3
Molecular Weight111.14773000
MDL NumberMFCD00005210
Nikkaji NumberJ4.117C
Beilstein0002012
XlogP3-0.70 (est)

Regulatory

Physical Properties

Appearance white needles (est)
Assay 95.00 to 100.00
Food Chemicals Codex Listed No
Melting Point 86.00 °C. @ 760.00 mm Hg
Boiling Point 380.29 °C. @ 760.00 mm Hg (est)
Flash Point 357.00 °F. TCC ( 180.30 °C. ) (est)
logP (o/w) -0.700
Soluble in water, 1e+006 mg/L @ 25 °C (est)

No sensory data available

Safety Information

Preferred SDSView
Oral/Parenteral Toxicityintravenous-dog LD50 7 mg/kg
Dermal Toxicitysubcutaneous-cat LDLo 34 mg/kg
Inhalation ToxicityNot determined

GHS Classification

['GHS Classification in accordance with 29 CFR 1910 (OSHA HCS)', 'GHS Label elements, including precautionary statements', 'CARDIAC: PULSE RATE INCREASE WITHOUT FALL IN BP\nLUNGS, THORAX, OR RESPIRATION: RESPIRATORY STIMULATION\nBEHAVIORAL: ALTERED SLEEP TIME (INCLUDING CHANGE IN RIGHTING REFLEX)']

Safety in Use

Categorynatural substances and extractives
Recommendation for histamine usage levels up tonot for fragrance use.
Recommendation for histamine flavor usage levels up tonot for flavor use.

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Potential Uses

None Found

Natural Occurrence

banana banana fruit cabbage leaf cantaloupe fruit cantaloupe juice dragonwort pea shoot spinach spinach plant sunflower tissue culture

Synonyms

4-(2- aminoethyl)-1H-imidazole beta- aminoethylglyoxaline beta- aminoethylimidazole ergamine ergotidine ethylamine, 2-imidazol-4-yl- 2- imidazol-4-yl ethyl amine 2- imidazol-4-yl ethylamine 2-(1H- imidazol-5-yl)ethanamine 1H- imidazole-4-ethanamine imidazole, 4-(2-aminoethyl)- 5- imidazoleethylamine beta- imidazolyl-4-ethylamine 2-(4- imidazolyl)ethylamine istamina theramine Info: Histamine PubMed: (-)-Carvone: antispasmodic effect and mode of action. PubMed: Use of Tetragenococcus halophilus as a starter culture for flavor improvement in fish sauce fermentation. PubMed: Electrophysiological analysis of the mechanism of autonomic action by lactobacilli. PubMed: Effects of Urtica dioica and Hibiscus sabdariffa on the quality and safety of sucuk (Turkish dry-fermented sausage). PubMed: Determination of the biogenic amines in musts and wines before and after malolactic fermentation using 6-aminoquinolyl-N-hydroxysuccinimidyl carbamate as the derivatizing agent. PubMed: Acceptance survey of a fast dissolving tablet pharmaceutical formulation in allergic patients. Satisfaction and expectancies. PubMed: Functional effects of Japanese style fermented soy sauce (shoyu) and its components. PubMed: Adverse reactions to foods.