homovanillyl alcohol
benzeneethanol, 4-hydroxy-3-methoxy-
Identification
| Name | homovanillyl alcohol |
| IUPAC | 4-(2-hydroxyethyl)-2-methoxyphenol |
| CAS Number | 2380-78-1 |
| EINECS | 219-175-1 |
| FDA UNII | 9A7EE8MS6A |
| Molecular Formula | C9 H12 O3 |
| Molecular Weight | 168.19224000 |
| MDL Number | MFCD00002903 |
| Nikkaji Number | J172D |
| XlogP3 | 0.50 (est) |
Regulatory
Physical Properties
| Assay | 98.00 to 100.00 |
| Food Chemicals Codex Listed | No |
| Melting Point | 40.00 to 42.00 °C. @ 760.00 mm Hg |
| Boiling Point | 316.00 to 317.00 °C. @ 760.00 mm Hg (est) |
| Vapor Pressure | 0.000169 mmHg @ 25.00 °C. (est) |
| Flash Point | > 230.00 °F. TCC ( > 113.00 °C. ) |
| logP (o/w) | 0.470 |
| Soluble in | alcohol |
No sensory data available
Safety Information
| Preferred SDS | View |
| Oral/Parenteral Toxicity | Not determined |
| Dermal Toxicity | Not determined |
| Inhalation Toxicity | Not determined |
GHS Classification
['GHS Classification in accordance with 29 CFR 1910 (OSHA HCS)', 'GHS Label elements, including precautionary statements']
Safety in Use
| Category | flavor and fragrance agents |
| RIFM Fragrance Material Safety Assessment | Search |
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Potential Uses
Natural Occurrence
Synonyms
benzeneethanol, 4-hydroxy-3-methoxy-
4-
hydroxy-3-methoxyphenethanol
4-
hydroxy-3-methoxyphenethyl alcohol
2-(4-
hydroxy-3-methoxyphenyl)ethanol
4-
hydroxy-3-methoxyphenylethyl alcohol
4-(2-
hydroxyethyl) guaiacol
4-(2-
hydroxyethyl)-2-methoxyphenol
4-(2-
hydroxyethyl)-2-methoxyphenol
4-(2-
hydroxyethyl)guaiacol
3-
methoxy-4-hydroxyphenylethanol
homo
vanillin alcohol
homo
vanillylalcohol
PubMed:
Enzymatic surface erosion of high tensile strength polycarbonates based on natural phenols.
PubMed:
Simultaneous determination of phenylethanoid glycosides and aglycones by capillary zone electrophoresis with running buffer modifier.
PubMed:
Dose-dependent metabolic disposition of hydroxytyrosol and formation of mercapturates in rats.
PubMed:
Protective activity of hydroxytyrosol metabolites on erythrocyte oxidative-induced hemolysis.
PubMed:
Picea mariana bark: a new source of trans-resveratrol and other bioactive polyphenols.
PubMed:
Phenylpropanoid glycoside analogues: enzymatic synthesis, antioxidant activity and theoretical study of their free radical scavenger mechanism.
PubMed:
Antioxidant activities of hydroxytyrosol main metabolites do not contribute to beneficial health effects after olive oil ingestion.
PubMed:
Simultaneous quantification of oleuropein and its metabolites in rat plasma by liquid chromatography electrospray ionization tandem mass spectrometry.
PubMed:
Dopamine receptor activation by honey bee queen pheromone.
PubMed:
Olive oil phenolic compounds inhibit homocysteine-induced endothelial cell adhesion regardless of their different antioxidant activity.
PubMed:
Detection and quantification of phenolic compounds in olive oil by high resolution 1H nuclear magnetic resonance spectroscopy.
PubMed:
Convenient synthesis of hydroxytyrosol and its lipophilic derivatives from tyrosol or homovanillyl alcohol.
PubMed:
Inhibition of platelet aggregation by olive oil phenols via cAMP-phosphodiesterase.
PubMed:
Queen pheromone modulates brain dopamine function in worker honey bees.
PubMed:
Minor components of olive oil modulate proatherogenic adhesion molecules involved in endothelial activation.
PubMed:
Daily consumption of a high-phenol extra-virgin olive oil reduces oxidative DNA damage in postmenopausal women.
PubMed:
Hydroxytyrosol excretion differs between rats and humans and depends on the vehicle of administration.
PubMed:
Olive oils rich in natural catecholic phenols decrease isoprostane excretion in humans.
PubMed:
The effect of low-level deoxynivalenol on neurotransmitter levels measured in pig cerebral spinal fluid.
PubMed:
Preparation of an optimum mobile phase for the simultaneous determination of neurochemicals in mouse brain tissues by high-performance liquid chromatography with electrochemical detection.
PubMed:
Human class I alcohol dehydrogenases catalyze the interconversion of alcohols and aldehydes in the metabolism of dopamine.
PubMed:
[Assay of urinary homovanillic acid by gas phase chromatography with a capillary tube].