hydrocortisone

17-hydroxycorticosterone

CAS: 50-23-7 C21 H30 O5 MW: 362.46610000

Identification

Namehydrocortisone
IUPAC(8S,9S,10R,11S,13S,14S,17R)-11,17-dihydroxy-17-(2-hydroxyacetyl)-10,13-dimethyl-2,6,7,8,9,11,12,14,15,16-decahydro-1H-cyclopenta[a]phenanthren-3-one
CAS Number50-23-7
EINECS200-020-1
FDA UNIIWI4X0X7BPJ
Molecular FormulaC21 H30 O5
Molecular Weight362.46610000
MDL NumberMFCD00011654
Nikkaji NumberJ1.908I
XlogP31.60 (est)

Regulatory

Physical Properties

Assay 95.00 to 100.00
Food Chemicals Codex Listed No
Melting Point 220.00 °C. @ 760.00 mm Hg
Boiling Point 566.45 °C. @ 760.00 mm Hg (est)
Vapor Pressure 1.350000 mmHg @ 25.00 °C. (est)
Flash Point 591.00 °F. TCC ( 310.40 °C. ) (est)
logP (o/w) 1.610
Soluble in water, 320 mg/L @ 25 °C (exp)

No sensory data available

Safety Information

Preferred SDSView
Oral/Parenteral Toxicityoral-man TDLo 400 mg/kg/10D-
Dermal Toxicitysubcutaneous-mouse LD50 > 500 mg/kg
Inhalation ToxicityNot determined

GHS Classification

['GHS Classification in accordance with 29 CFR 1910 (OSHA HCS)', 'GHS Label elements, including precautionary statements']

Safety in Use

Categorypharmaceuticals / chemical synthisis
Recommendation for hydrocortisone usage levels up tonot for fragrance use.
Recommendation for hydrocortisone flavor usage levels up tonot for flavor use.

American International Chemical, Inc.

Consistent sources

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Glentham Life Sciences Ltd

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Penta International Corporation

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Potential Uses

None Found

Natural Occurrence

not found in nature

Synonyms

acticort aeroseb-HC ala-cort ala-scalp anucort-HC anusol HC anusol-HC balneol-HC barseb HC cetacort cobadex colocort corhydron cort-dome cortanal cortenema corticreme cortifan cortiment cortisol alcohol cortispray cortolotion cortonema cortoxide cortril cremesone delacort dermacort dermocortal dermolate dihydrocostisone (8S,9S,10R,11S,13S,14S,17R)-11,17- dihydroxy-17-(2-hydroxyacetyl)-10,13-dimethyl-2,6,7,8,9,11,12,14,15,16-decahydro-1H-cyclopenta[a]phenanthren-3-one dioderm dome-cort domolene-HC efcorbin efcortelan efcortelin eldecort eldercort epicort epiderm H esiderm H evacort ficortril flexicort genacort glycort h-cort heb-cort hi-cor hidro-colisona hidrocortisona hycort hydrasson hydro-adreson hydro-colisona hydro-RX hydrocort hydroskin hydroxycorticosterone 17- hydroxycorticosterone hydroxycortisone hytone incortin-H kendall's compound F komed HC lacticare-HC locoid lubricort maintasone medicort meusicort mildison nogenic HC nutracort optef otosone-F penecort permicort polcort H pregn-4-ene-3,20-dione, 11,17,21-trihydroxy-, (11b)- pregn-4-ene-3,20-dione, 11b,17,21-trihydroxy- 4- pregnene-11b,17a,21-triol-3,20-dione rectoid reichstein's substance M scheroson F signef stie-cort synacort tarcortin texacort timocort traumaide (11b)-11,17,21- trihydroxypregn-4-ene-3,20-dione 11b,17,21- trihydroxyprogesterone zenoxone Try the PubMed Search.