hydroxypropyl cellulose

cellulose, 2-hydroxypropyl ether

CAS: 9004-64-2 C3 H8 O2.x-unspecified

Identification

Namehydroxypropyl cellulose
CAS Number9004-64-2
FDA UNII2165RE0K14
Molecular FormulaC3 H8 O2.x-unspecified
MDL NumberMFCD00132688

Regulatory

FDA/DG SANTE Petitions, Reviews, NoticesFR DOC # 2011-17928
JECFA Food AdditiveHydroxypropyl Cellulose
GSFA CodexHydroxypropyl cellulose (463)
DG SANTE Food Additiveshydroxypropyl cellulose
DG SANTE Food Contact Materialshydroxypropyl cellulose
FDA Mainterm (SATF)9004-64-2 ; HYDROXYPROPYL CELLULOSE
FDA RegulationFDA PART 172 -- FOOD ADDITIVES PERMITTED FOR DIRECT ADDITION TO FOOD FOR HUMAN CONSUMPTION

Physical Properties

Appearance white to pale yellow powder (est)
Assay 95.00 to 100.00
Food Chemicals Codex Listed No

Cosmetic Information

CosIngcosmetic data
Cosmetic Usesbinding agents

Organoleptic Properties

Odor Description at 100.00 %.

Safety Information

Preferred SDSView
Oral/Parenteral Toxicityoral-rat LD50 10200 mg/kg
Dermal ToxicityNot determined
Inhalation ToxicityNot determined

GHS Classification

['GHS Classification in accordance with 29 CFR 1910 (OSHA HCS)', 'GHS Label elements, including precautionary statements']

Safety in Use

Categorymultipurpose additives, foam promoter, mouthfeel, stabilizer
Recommendation for hydroxypropyl cellulose usage levels up tonot for fragrance use.
Recommendation for hydroxypropyl cellulose flavor usage levels up tonot for flavor use.

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Potential Uses

binding agents emulsion stabilisers film formers gel forming agents for perfumes viscosity controlling agents

Natural Occurrence

not found in nature

Synonyms

cellulose 2-hydroxypropyl ether cellulose hydroxypropyl ether cellulose, 2-hydroxypropyl ether 2- hydroxypropyl cellulose hydroxypropyl ether of cellulose hydroxypropylcellulose oxy propylated cellulose PubMed: Interactive forces between lignin and cellulase as determined by atomic force microscopy. PubMed: High pressure homogenization to improve the stability of casein - hydroxypropyl cellulose aqueous systems. PubMed: Fast and interference-free determination of glyphosate and glufosinate residues through electrophoresis in disposable microfluidic chips. PubMed: Effects of molecular weight on permeability and microstructure of mixed ethyl-hydroxypropyl-cellulose films. PubMed: Hydration properties of regioselectively etherified celluloses monitored by 2H and 13C solid-state MAS NMR spectroscopy. PubMed: Characterization of critical physical and mechanical properties of freeze-dried grape powder for development of a clinical patient delivery system. PubMed: Lipoic acid nanoparticles: effect of polymeric stabilizer on appetite suppression. PubMed: Formulation and evaluation of gastroretentive drug delivery system of propranolol hydrochloride. PubMed: New bioactive biomaterials based on quaternized chitosan. PubMed: Stabilization of hot-melt extrusion formulations containing solid solutions using polymer blends. PubMed: In-vitro/in-vivo correlation of pulsatile drug release from press-coated tablet formulations: a pharmacoscintigraphic study in the beagle dog. PubMed: Effect of water content on the structural reorganization and elastic properties of biopolymer films: a comparative study. PubMed: From physical pharmacy to clinical pharmacology. PubMed: Pharmacokinetics of a slow-release formulation of soybean isoflavones in healthy postmenopausal women. PubMed: DNA separation by capillary electrophoresis with hydrophilic substituted celluloses as coating and sieving polymers. Application to the analysis of genetically modified meals. PubMed: Comparison of neural network and multiple linear regression as dissolution predictors. PubMed: Sol-gel composite films with controlled release of biocides. PubMed: Isolation and characterization of the viscous, high-molecular-mass microbial carbohydrate fraction from faeces of healthy subjects and patients with Crohn's disease and the consequences for a therapeutic approach. PubMed: Adherence of two film-forming medications to the oral mucosa. PubMed: Evaluation of the correlation between in vivo and in vitro release. Effect of the force of contraction and food on drug release. PubMed: [Anaphylaxis caused by carboxymethylcellulose: report of 2 cases of shock from injectable corticoids].