1H-benzo[d]azoline-2,3-dione

CAS: 91-56-5 C8 H5 N O2 MW: 147.13325000

Identification

Nameisatin
IUPAC1H-indole-2,3-dione
CAS Number91-56-5
EINECS202-077-8
FDA UNII82X95S7M06
Molecular FormulaC8 H5 N O2
Molecular Weight147.13325000
MDL NumberMFCD00005718
Nikkaji NumberJ4.342G
Beilstein0383659
XlogP30.80 (est)

Regulatory

Physical Properties

Assay 95.00 to 100.00
Food Chemicals Codex Listed No
Melting Point 203.00 °C. @ 760.00 mm Hg
Boiling Point 360.30 °C. @ 760.00 mm Hg (est)
Vapor Pressure 0.000001 mmHg @ 25.00 °C. (est)
Flash Point 341.00 °F. TCC ( 171.70 °C. ) (est)
logP (o/w) 0.830
Soluble in water, 1.527e+004 mg/L @ 25 °C (est)

Cosmetic Information

CosIngcosmetic data
Cosmetic Useshair dyeing agents

No sensory data available

Safety Information

Preferred SDSView
Oral/Parenteral Toxicityintraperitoneal-mouse LD50 330 mg/kg
Dermal ToxicityNot determined
Inhalation ToxicityNot determined

GHS Classification

['GHS Classification in accordance with 29 CFR 1910 (OSHA HCS)', 'GHS Label elements, including precautionary statements']

Safety in Use

Categorycosmetic agents
Recommendation for isatin usage levels up tonot for fragrance use.
Recommendation for isatin flavor usage levels up tonot for flavor use.

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Potential Uses

None Found

Natural Occurrence

not found in nature

Synonyms

1H- benzo[d]azoline-2,3-dione 2,3- diketoindoline 2,3- dioxo-2,3-dihydroindole 2,3- dioxoindoline 3- hydroxy-2-oxoindole indole-2,3-dione 1H- indole-2,3-dione indolequinone indoline-2,3-dione 2,3- indolinedione PubMed: Mediators involved in the hyperthermic action of neuromedin U in rats. PubMed: 5-(2-carboxyethenyl) isatin derivative induces G₂/M cell cycle arrest and apoptosis in human leukemia K562 cells. PubMed: Synthesis and in vitro antioxidant activity of new 3-substituted-2-oxindole derivatives. PubMed: Rapid method for proline determination in grape juice and wine. PubMed: Chemical synthesis, in vitro acetohydroxyacid synthase (AHAS) inhibition, herbicidal activity, and computational studies of isatin derivatives. PubMed: Organophosphorus derivatives containing isatin-3-hydrazones as chemotherapeutants against fungal pathogens of sugarcane. PubMed: Stress-induced increase in urinary isatin excretion in rats: reversal by both dexamethasone and alpha-methyl-P-tyrosine. PubMed: Isatin inhibits food intake in mice. PubMed: On the functions of monoamine oxidase, the emotions, and adaptation to stress. PubMed: The response of some intravascular and intracellular lipid parameters of the rat after treatment with isatin.