isoniacinamide

4- carbamoylpyridine iso nicotinamide iso nicotinic acid amide pyridine-4-carboxamide 4- pyridinecarboxamide gamma- pyridinecarboxamide Google Patents: Multicomponent crystalline system comprising deferasirox and isonicotinamide and a process for the preparation thereof PubMed: Antitubercular activity of Ru (II) isoniazid complexes. PubMed: Improving the dissolution and bioavailability of 6-mercaptopurine via co-crystallization with isonicotinamide. PubMed: Potential of multisyringe chromatography for the on-line monitoring of the photocatalytic degradation of antituberculosis drugs in aqueous solution. PubMed: Synthesis and anti-mycobacterial activity of new 4-thiazolidinone and 1,3,4-oxadiazole derivatives of isoniazid. PubMed: Large thermal hysteresis for iron(II) spin crossover complexes with N-(pyrid-4-yl)isonicotinamide. PubMed: Structures and spectroscopic characterization of calcium chloride-nicotinamide, -isonicotinamide, -picolinamide and praseodymium bromide-nicotinamide complexes. PubMed: A pillared framework coordination polymer based on the Cd3(μ3-OH) unit: poly[[(μ4-5-aminotetrazolato-κ(4)N(1):N(2):N(3):N(4))chlorido-μ3-hydroxido-(μ3-isonicotinato-κ(3)N:O:O')dicadmium(II)] 0.14-hydrate]. PubMed: Self-association during heterogeneous nucleation onto well-defined templates. PubMed: Discovery of MK-3697: a selective orexin 2 receptor antagonist (2-SORA) for the treatment of insomnia. PubMed: A Lewis acid-mediated conformational switch. PubMed: Targeted structure modulation of "pillar-layered" metal-organic frameworks for CO₂ capture. PubMed: Acemetacin cocrystals and salts: structure solution from powder X-ray data and form selection of the piperazine salt. PubMed: Photophysics of bis-bipyridyl nitro complexes of ruthenium(II) with pyridine ligands: substituent effects. PubMed: Novel modified carbon nanotubes as a selective sorbent for preconcentration and determination of trace copper ions in fruit samples. PubMed: Diversity-oriented synthesis yields a new drug lead for treatment of chagas disease. PubMed: Orally active microtubule-targeting agent, MPT0B271, for the treatment of human non-small cell lung cancer, alone and in combination with erlotinib. PubMed: Incidence of mucositis in patients treated with temsirolimus-based regimens and correlation to treatment response. PubMed: Structural landscape of the 1 : 1 benzoic acid : isonicotinamide cocrystal. PubMed: Protective effects of a nicotinamide derivative, isonicotinamide, against streptozotocin-induced β-cell damage and diabetes in mice. PubMed: Preparation and characterization of a novel Wells-Dawson heteropolyacid-based magnetic inorganic-organic nanohybrid catalyst H6P2W18O62/pyridino-Fe3O4 for the efficient synthesis of 1-amidoalkyl-2-naphthols under solvent-free conditions. PubMed: A 1:2 cocrystal of genistein with isonicotinamide: crystal structure and Hirshfeld surface analysis. PubMed: The MEK1/2 inhibitor AS703026 circumvents resistance to the BRAF inhibitor PLX4032 in human malignant melanoma cells. PubMed: N-Methylanilide and N-methylbenzamide derivatives as phosphodiesterase 10A (PDE10A) inhibitors. PubMed: Novel agents and future prospects in the treatment of pancreatic adenocarcinoma. PubMed: Bis(μ-4-formyl-benzoato-κ(2) O:O')bis-[(4-formyl-benzoato-κ(2) O,O')bis-(iso-nicotin-amide-κN (1))copper(II)]. PubMed: trans-Tetra-aqua-bis-(isonicotinamide-κN (1))zinc bis-(3-hy-droxy-benzoate) tetra-hydrate. PubMed: Spirocyclic dihydropyridines by electrophile-induced dearomatizing cyclization of N-alkenyl pyridinecarboxamides. PubMed: catena-Poly[[aquabis[N-(pyridin-3-yl)isonicotinamide-κN (1)]copper(II)]-μ-fumarato-κ(2) O (1):O (4)]. PubMed: Surface-enhanced Raman scattering of picolinamide, nicotinamide, and isonicotinamide: unusual carboxamide deprotonation under adsorption on silver nanoparticles. PubMed: L2,3-edge x-ray absorption near-edge spectroscopy analysis of photoisomerism in solid ruthenium-sulfur dioxide complexes. PubMed: cis-(2,2'-Bipyridine-κ(2)N,N')bis-(isonicotinamide-κN(1))palladium(II) bis-(hexa-fluoridophosphate). PubMed: 4-Carbamoylpyridin-1-ium 2,2,2-tri-chloro-acetate-isonicotinamide (1/1). PubMed: Selective detection of multicarboxylate anions based on "turn on" electron transfer by self-assembled molecular rectangles. PubMed: Two ligand-functionalized Pb(II) metal-organic frameworks: structures and catalytic performances. PubMed: Diaqua-bis-[N-(pyridin-4-yl)isonicotin-amide-κN]bis-(thio-cyanato-κN)cobalt(II). PubMed: Systematic evaluation of textural properties, activation temperature and gas uptake of Cu2(pzdc)2L [L = dipyridyl-based ligands] porous coordination pillared-layer networks. PubMed: Anticancer Activity of Self-Assembled Molecular Rectangles via Arene-Ruthenium Acceptors and a New Unsymmetrical Amide Ligand. PubMed: Unusual co-crystal of isonicotinamide: the structural landscape in crystal engineering. PubMed: Isonicotinamide enhances Sir2 protein-mediated silencing and longevity in yeast by raising intracellular NAD+ concentration. PubMed: Nocardia globerula NHB-2 nitrilase catalysed biotransformation of 4-cyanopyridine to isonicotinic acid. PubMed: Isonicotinamide self-association: the link between solvent and polymorph nucleation. PubMed: Novel acridinedione derivatives: design, synthesis, SIRT1 enzyme and tumor cell growth inhibition studies. PubMed: Synthesis of highly potent novel anti-tubercular isoniazid analogues with preliminary pharmacokinetic evaluation. PubMed: catena-Poly[[(μ-3-hy-droxy-benzoato-κO,O:O)(μ-3-hy-droxy-benzoato-κO,O:O)(isonicotinamide-κN)-lead(II)] monohydrate]. PubMed: trans-Tetra-aqua-bis-(isonicotinamide-κN)cobalt(II) bis-(3-hy-droxy-benzoate) tetra-hydrate. PubMed: Mechanical stress-activated immune response genes via Sirtuin 1 expression in human periodontal ligament cells. PubMed: trans-Tetra-aqua-bis-(isonicotinamide-κN)nickel(II) bis-(3-hy-droxy-benzoate) tetra-hydrate. PubMed: Isonicotinamide-2-naphthoic acid (1/1). PubMed: Novel furosemide cocrystals and selection of high solubility drug forms. PubMed: Coordination-driven self-assembly of 2D-metallamacrocycles using a shape-selective Pt(II)2-organometallic 90° acceptor: design, synthesis and sensing study. PubMed: Isoniazid metal complex reactivity and insights for a novel anti-tuberculosis drug design. PubMed: Nuclear quadrupole resonance study of hydrogen bonded solid materials. PubMed: Cocrystals of quercetin with improved solubility and oral bioavailability. PubMed: Extending the supramolecular synthon based fragment approach (SBFA) for transferability of multipole charge density parameters to monofluorobenzoic acids and their cocrystals with isonicotinamide: importance of C-H···O, C-H···F, and F···F intermolecular regions. PubMed: Antinociceptive and anti-inflammatory activities of nicotinamide and its isomers in different experimental models. PubMed: The role of sirtuin 1 in osteoblastic differentiation in human periodontal ligament cells. PubMed: Sir2 is induced by oxidative stress in a yeast model of Huntington disease and its activation reduces protein aggregation. PubMed: Microwave assisted one-pot synthesis of highly potent novel isoniazid analogues. PubMed: MEK1/2 inhibitors AS703026 and AZD6244 may be potential therapies for KRAS mutated colorectal cancer that is resistant to EGFR monoclonal antibody therapy. PubMed: New polymorphs of isonicotinamide and nicotinamide. PubMed: 14N NQR study of polymorphism and hydrogen bonding in molecular complex isonicotinamide-oxalic acid (2:1). PubMed: Antimycobacterial and antitumor activities of palladium(II) complexes containing isonicotinamide (isn): X-ray structure of trans-[Pd(N3)2(isn)(2)]. PubMed: Solubility, metastable zone width measurement and crystal growth of the 1:1 benzoic acid/isonicotinamide cocrystal in solutions of variable stoichiometry. PubMed: Structure elucidation of highly polar basic degradants by on-line hydrogen/deuterium exchange hydrophilic interaction chromatography coupled to tandem mass spectrometry. PubMed: Synthesis and in vitro evaluation of substituted pyrimido[5,4-d]pyrimidines as a novel class of anti-Mycobacterium tuberculosis agents. PubMed: Direct electrochemistry of cytochrome c at modified Si(100) electrodes. PubMed: Blockade of the MEK/ERK signalling cascade by AS703026, a novel selective MEK1/2 inhibitor, induces pleiotropic anti-myeloma activity in vitro and in vivo. PubMed: Bis(isonicotinamide-κN)bis-(4-methyl-benzoato-κO)copper(II) dihydrate. PubMed: Diaqua-(isonicotinamide-κN)(4-meth-oxy-benzoato-κO,O')(4-meth-oxy-benzoato-κO)cobalt(II). PubMed: Aqua-bis(isonicotinamide-κN)bis-(4-methyl-benzoato)-κO;κO,O'-cadmium(II) monohydrate. PubMed: Tetra-kis(μ-4-methyl-benzoato-κO:O')bis-[(isonicotinamide-κN)copper(II)]. PubMed: Di-μ-acetato-bis-[(acetato-κO,O')bis-(iso-nicotinamide-κN)copper(II)]. PubMed: Experimental and theoretical charge density study of polymorphic isonicotinamide-oxalic acid molecular complexes with strong O...H...N hydrogen bonds. PubMed: Multinuclear NMR and theoretical investigation on interactions between diperoxovanadate complex and 4-picoline-like ligands. PubMed: Biochemical effects of SIRT1 activators. PubMed: One-pot mechanosynthesis with three levels of molecular self-assembly: coordination bonds, hydrogen bonds and host-guest inclusion. PubMed: Uncommon isonicotinamide supramolecular synthons in copper(II) complexes directed by nitrate and perchlorate anions. PubMed: Activation of SIRT1 by resveratrol represses transcription of the gene for the cytosolic form of phosphoenolpyruvate carboxykinase (GTP) by deacetylating hepatic nuclear factor 4alpha. PubMed: Experimental chemotherapy against Trypanosoma cruzi infection using ruthenium nitric oxide donors. PubMed: Continuous hydrolysis of 4-cyanopyridine by nitrilases from Fusarium solani O1 and Aspergillus niger K10. PubMed: Effect of soft segment crystallization and hard segment physical crosslink on shape memory function in antibacterial segmented polyurethane ionomers. PubMed: Resveratrol inhibits proliferation and promotes apoptosis of osteosarcoma cells. PubMed: Zero-, one- and two-dimensional hydrogen-bonded structures in the 1:1 proton-transfer compounds of 4,5-dichlorophthalic acid with the monocyclic heteroaromatic Lewis bases 2-aminopyrimidine, nicotinamide and isonicotinamide. PubMed: Diaqua-bis[4-(dimethyl-amino)benzoato](isonicotinamide)zinc(II). PubMed: Diaqua-bis[4-(dimethyl-amino)-benzoato]-κO,O';κO-(isonicotinamide-κN)cobalt(II). PubMed: Aqua-bis(4-formyl-benzoato-κO,O)bis-(isonicotinamide-κN)cadmium(II) monohydrate. PubMed: catena-Poly[[(4-formyl-benzoato-κO)(isonicotinamide-κN)zinc(II)]-μ-4-formyl-benzoato-κO:O]. PubMed: Bis(isonicotinamide-κN)bis-[4-(methyl-amino)benzoato]zinc(II) monohydrate. PubMed: Tetra-aqua-bis(isonicotinamide-κN)cobalt(II) bis-(4-formyl-benzoate) dihydrate. PubMed: Tetra-aqua-bis(isonicotinamide-κN)nickel(II) bis-(4-formyl-benzoate) dihydrate. PubMed: Diaqua-bis[4-(dimethyl-amino)benzoato-κO](isonicotinamide-κN)manganese(II). PubMed: Design, synthesis, and characterizations of a series of Pt(4) macrocycles and fluorescent sensing of Fe3+/Cu2+/Ni2+ through metal coordination. PubMed: Chiral carboxylic acids and their effects on melting-point behaviour in co-crystals with isonicotinamide. PubMed: Self-assembly of electroactive thiacrown ruthenium(II) complexes into hydrogen-bonded chain and tape networks. PubMed: Oxidation of catechin and rutin by pentaammineruthenium(III) complexes. PubMed: Nitrosation of N-methylhydroxylamine by nitroprusside. A kinetic and mechanistic study. PubMed: Zipped-up chain-type coordination polymers: unsymmetrical amide-containing ligands inducing beta-sheet or helical structures. kazu-u@yamaguchi-u.ac.jp. PubMed: Design and synthesis of 6-fluoro-2-naphthyl derivatives as novel CCR3 antagonists with reduced CYP2D6 inhibition. PubMed: Activation of Sirt1 decreases adipocyte formation during osteoblast differentiation of mesenchymal stem cells. PubMed: Electrophile-induced dearomatizing spirocyclization of N-arylisonicotinamides: a route to spirocyclic piperidines. PubMed: A structure-activity analysis of the variation in oxime efficacy against nerve agents. PubMed: NMR and theoretical study on interactions between diperoxovanadate complex and 4-substituted pyridines. PubMed: Isoniazid: metabolic aspects and toxicological correlates. PubMed: Molecular structure, vibrational spectra, quantum chemical calculations and photochemistry of picolinamide and isonicotinamide isolated in cryogenic inert matrixes and in the neat low-temperature solid phases. PubMed: 14N NQR study of nicotinamide and related compounds. PubMed: Metalloporphyrin-based inclusion materials: exploiting ligating topologies and hydrogen-bonding backbones in generating new supramolecular architectures. PubMed: A novel oral indoline-sulfonamide agent, N-[1-(4-methoxybenzenesulfonyl)-2,3-dihydro-1H-indol-7-yl]-isonicotinamide (J30), exhibits potent activity against human cancer cells in vitro and in vivo through the disruption of microtubule. PubMed: Synthesis and structure of silver complexes with nicotinate-type ligands having antibacterial activities against clinically isolated antibiotic resistant pathogens. PubMed: Discovery of isonicotinamide derived beta-secretase inhibitors: in vivo reduction of beta-amyloid. PubMed: Discovery and SAR of isonicotinamide BACE-1 inhibitors that bind beta-secretase in a N-terminal 10s-loop down conformation. PubMed: Ligand-based design, synthesis and primary in vivo screening of pyrrole derivatives as potential tricyclic anti-inflammatory agents. PubMed: A regenerable ruthenium tetraammine nitrosyl complex immobilized on a modified silica gel surface: preparation and studies of nitric oxide release and nitrite-to-NO conversion. PubMed: LC and LC-MS study of stress decomposition behaviour of isoniazid and establishment of validated stability-indicating assay method. PubMed: Utilization of host SR protein kinases and RNA-splicing machinery during viral replication. PubMed: The amide rotational barrier in isonicotinamide: Dynamic NMR and ab initio studies. PubMed: Activation of Sirt1 decreases adipocyte formation during osteoblast differentiation of mesenchymal stem cells. PubMed: [Modulation of reactivity of cyclic adenosine monophosphate phosphodiesterase under the effect of pyridinecarboxylic acid derivatives and Pt(IV) metal complexes on their basis]. PubMed: Catalase-peroxidase of Mycobacterium bovis BCG converts isoniazid to isonicotinamide, but not to isonicotinic acid: differentiation parameter between enzymes of Mycobacterium bovis BCG and Mycobacterium tuberculosis. PubMed: Carboxamide-pyridine N-oxide heterosynthon for crystal engineering and pharmaceutical cocrystals. PubMed: Proton sharing in bis(4-carbamoylpyridinium) squarate. PubMed: Practical synthesis of a neuropeptide Y antagonist via stereoselective addition to a ketene. PubMed: catena-Poly[[[diaquabis(pyridine-4-carboxamide-kappaN)copper(II)]-mu2-squarato-kappaO1:O3] dihydrate]. PubMed: Synthesis and characterization of hydrogen-bonded assemblies of W6S8L6 clusters. PubMed: Chemical activation of Sir2-dependent silencing by relief of nicotinamide inhibition. PubMed: Nonpolymeric hydrogelator derived from N-(4-pyridyl)isonicotinamide. PubMed: Selectivity of effects of redox-active cobalt(III) complexes on tumor tissue. PubMed: A contrivance for a dynamic porous framework: cooperative guest adsorption based on square grids connected by amide-amide hydrogen bonds. PubMed: Structure-based optimization of novel azepane derivatives as PKB inhibitors. PubMed: Self-assembly in palladium(II) and platinum(II) chemistry: the biomimetic approach. PubMed: Hydrogen-bonded extended arrays of the [Re6(mu3-Se)8]2+ core-containing clusters. PubMed: Ruthenium bisbipyridine complexes of horse heart cytochrome c: characterization and comparative intramolecular electron-transfer rates determined by pulse radiolysis and flash photolysis. PubMed: (Acetonitrile)[2,6-bis(pyrazol-1-yl)pyridine](isonicotinamide)copper(II)-tetrafluoroborate-acetonitrile (1/2/2). PubMed: Variation in the coordination mode of arenedisulfonates: syntheses and structural characterization of mononuclear and dinuclear cadmium(II) arenedisulfonate complexes with two- to zero-dimensional architectures. PubMed: Novel flexible frameworks of porous cobalt(II) coordination polymers that show selective guest adsorption based on the switching of hydrogen-bond pairs of amide groups. PubMed: Copper complexes with bioactive ligands. Part II--Antifungal activity. PubMed: Mn(III) pyrophosphate as an efficient tool for studying the mode of action of isoniazid on the InhA protein of Mycobacterium tuberculosis. PubMed: Cooperative ligation, back-bonding, and possible pyridine-pyridine interactions in tetrapyridine-vanadium(II): a visible and X-ray spectroscopic study. PubMed: Copper complexes with bioactive ligands Part I--Antimicrobial activity. PubMed: Kinetics and mechanism of ligand interchange in pentacyano-L-osmate(II) complexes (L = H(2)O, NH(3), N-heterocyclic ligands). PubMed: Self-assembly of polymer and sheet structures from palladium(II) complexes by hydrogen bonding between carboxamide substituents. PubMed: Inhibition of cancer cell growth by ruthenium(II) arene complexes. PubMed: Oxidation of [Ru(NH3)5isn](BF4)2 by hyochlorous acid and chlorine in aqueous acidic media. PubMed: Synthesis and characterization of non-leaching biocidal polyurethanes. PubMed: Molecularly imprinted polymers from nicotinamide and its positional isomers. PubMed: Surface-enhanced raman spectra of some anti-tubercle bacillus drugs. PubMed: Apoptosis induced by niacin-related compounds in K562 cells but not in normal human lymphocytes. PubMed: Apoptosis induced by nicotinamide-related compounds and quinolinic acid in HL-60 cells. PubMed: [Vitamins and apoptosis--induction of apoptosis in human cancer cells by nicotinic acid-related compounds]. PubMed: Apoptosis induced by niacin-related compounds in HL-60 cells. PubMed: A novel ternary ligand system for 99mTc-labeling of hydrazino nicotinamide-modified biologically active molecules using imine-N-containing heterocycles as coligands. PubMed: Cloning and characterization of a probenazole-inducible gene for an intracellular pathogenesis-related protein in rice. PubMed: Maintenance of phenobarbital-inducible Cyp2b gene expression in C57BL/6 mouse hepatocytes in primary culture as spheroids. PubMed: Elevated expression of the Cyp1a2 gene in the presence of nicotinamide by adult mouse hepatocytes in primary culture. PubMed: Translational activation of ethanol-inducible cytochrome P450 (CYP2E1) by isoniazid. PubMed: Effects of nicotinamide and its isomers on iron-induced renal damage. PubMed: Solubility enhancement of some water-insoluble drugs in the presence of nicotinamide and related compounds. PubMed: [Fluorometric determination of pyridine and its derivatives by flow injection analysis]. PubMed: Abiotic transformations and decomposition kinetics of 4-carbamoyl-2'-[(hydroxyimino)methyl]-1,1'-(oxydimethylene)-bis(pyridin ium chloride) in aqueous phosphate buffers. PubMed: Studies on the stability and decomposition of the Hagedorn-oxime HLö 7 in aqueous solution. PubMed: The characterization of the protection by nicotinamide against the action of diabetogenic nitrosoureas. PubMed: Pertussis toxin-sensitive cholinergic inhibition of somatostatin release from canine D-cells. PubMed: Simultaneous micro-determination of nicotinamide and its major metabolites, N1-methyl-2-pyridone-5-carboxamide and N1-methyl-4-pyridone-3-carboxamide, by high-performance liquid chromatography. PubMed: Pertussis toxin facilitates secretagogue-induced catecholamine release from cultured bovine adrenal chromaffin cells. PubMed: Studies on the decomposition of the oxime HI 6 in aqueous solution. PubMed: Stability studies of bis(pyridiniumaldoxime) reactivators of organophosphate-inhibited acetylcholinesterase. PubMed: Activation of guanylate cyclase by E. coli heat-stable enterotoxin (STa). Modulation by NAD and pertussis toxin. PubMed: NADP+ enhances cholera and pertussis toxin-catalyzed ADP-ribosylation of membrane proteins. PubMed: Evidence for the generation of active oxygen by isoniazid treatment of extracts of Mycobacterium tuberculosis H37Ra. PubMed: Conversion of adrenergic mechanism from an alpha- to a beta-type during primary culture of rat hepatocytes. Accompanying decreases in the function of the inhibitory guanine nucleotide regulatory component of adenylate cyclase identified as the substrate of islet-activating protein. PubMed: Purification of NADPH-dependent enoyl-CoA reductase involved in the malonyl-CoA dependent fatty acid elongation system of Mycobacterium smegmatis. PubMed: Lack of carcinogenicity of nicotinamide and isonicotinamide following lifelong administration to mice. PubMed: Effects of nicotinamide, isonicotinamide, and bleomycin on DNA synthesis and repair in rat hepatocytes and hepatoma cells. PubMed: Reversed phase high-performance liquid chromatography of heterocyclic aromatic N-oxides: application to measurement of N-oxidation by microsomes and rat hepatocytes in primary culture. PubMed: Evidence that ligand formation is a mechanism underlying the maintenance of cytochrome P-450 in rat liver cell culture. Potent maintenance by metyrapone. PubMed: Tissue distribution and metabolism of drugs V: effect of secretin and pancreozymin on drug transport in rabbit pancreas. PubMed: Relationship between the ability of nicotinamide to maintain nicotinamide-adenine dinucleotide in rat liver cell culture and its effect on cytochrome P-450. PubMed: Effect of various alcohols on the intramuscular absorption of isonicotinamide in the rat. PubMed: Antibodies specific to isoniazid and isonicotinic acid. PubMed: The effect of dioxyphenylalanine (DOPA), amides and some potential sources of energy on the multiplication of Mycobacterium leprae. PubMed: Effect of some ionic and nonionic surfactants on the intramuscular absorption of isonicotinamide. PubMed: ELECTRIC MOMENT OF ISONICOTINAMIDE IN BENZENE AND DIOXANE SOLUTIONS. PubMed: POTENTIATION OF THE ANTI-LEUKEMIC EFFECTS OF 2-AMINOTHIADIAZOLE BY ISONICOTINAMIDE AND DERIVATIVES. PubMed: The actions of ambonestyl [N(2-diethylaminoethyl)-isonicotinamide] and quinidine on isolated rabbit atria. PubMed: The effect of 2-diethylaminoethyl-isonicotinamide on cardiac arrhythmia in man. PubMed: [Effect of 2-diethylaminoethyl isonicotinamide on some basic properties of myocardium & experimental arrhythmias]. PubMed: Pharmacologic and antiarrhythmic actions of ambonestyl (2-diethylaminoethyl-isonicotinamide) in man; preliminary report.