sodium ascorbate

monosodium L-ascorbate

CAS: 134-03-2 C6 H7 Na O6 MW: 198.10675928

Identification

Namesodium ascorbate
IUPACsodium (2R)-2-[(1S)-1,2-dihydroxyethyl]-4-hydroxy-5-oxo-2H-furan-3-olate
CAS Number134-03-2
EINECS205-126-1
FDA UNIIS033EH8359
Molecular FormulaC6 H7 Na O6
Molecular Weight198.10675928
MDL NumberMFCD00082340
Nikkaji NumberJ5.221C
Beilstein3767246

Regulatory

FDA/DG SANTE Petitions, Reviews, Notices182.3731
JECFA Food AdditiveSodium Ascorbate
GSFA CodexSodium ascorbate (301)
DG SANTE Food Additivessodium ascorbate
FDA Mainterm (SATF)134-03-2 ; SODIUM ASCORBATE
FDA RegulationFDA PART 155 -- CANNED VEGETABLES

Physical Properties

Appearance white crystalline powder (est)
Assay 99.00 to 100.00
Food Chemicals Codex Listed No
logP (o/w) -7.050 (est)
Soluble in water, 620000 mg/L @ 25 °C (exp)

Cosmetic Information

CosIngcosmetic data
Cosmetic Usesantioxidants

Organoleptic Properties

Odor Description at 100.00 %.

Safety Information

Preferred SDSView
Oral/Parenteral ToxicityNot determined
Dermal ToxicityNot determined
Inhalation ToxicityNot determined

GHS Classification

['GHS Classification in accordance with 29 CFR 1910 (OSHA HCS)', 'GHS Label elements, including precautionary statements']

Safety in Use

Categorypreservatives
Recommendation for sodium ascorbate usage levels up tonot for fragrance use.
Recommendation for sodium ascorbate flavor usage levels up tonot for flavor use.

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Potential Uses

antioxidants

Natural Occurrence

not found in nature

Synonyms

L- ascorbate, sodium L- ascorbic acid sodium salt L(+)- ascorbic acid sodium salt laevo- ascorbic acid sodium salt laevo- ascorbic acid sodium salt (1:1) L- ascorbic acid, monosodium salt L- ascorbic acid, sodium salt (1:1) sodium (2R)-2-[(1S)-1,2-bis(oxidanyl)ethyl]-4-oxidanyl-5-oxidanylidene-2H-furan-3-olate sodium (2R)-2-[(1S)-1,2-dihydroxyethyl]-4-hydroxy-5-oxo-2,5-dihydrofuran-3-olate sodium (2R)-2-[(1S)-1,2-dihydroxyethyl]-4-hydroxy-5-oxo-2H-furan-3-olate sodium L-ascorbate (+)- sodium L-ascorbate mono sodium L-ascorbate mono sodium laevo-ascorbate vitamin C sodium vitamin C sodium salt Info: EVALUATION OF CERTAIN FOOD ADDITIVES AND CONTAMINANTS PubMed: Characterization of polyphenol oxidase activity in Ataulfo mango. PubMed: Stability of microencapsulated L-5-methyltetrahydrofolate in fortified noodles. PubMed: Quantification of DNA through a fluorescence biosensor based on click chemistry. PubMed: Fluorescence sensor for Cu(II) in the serum sample based on click chemistry. PubMed: Vitamin (B1, B2, B3 and B6) content and oxidative stability of Gastrocnemius muscle from dry-cured hams elaborated with different nitrifying salt contents and by two ageing times. PubMed: Natural extracts versus sodium ascorbate to extend the shelf life of meat-based ready-to-eat meals. PubMed: Wheat rolls fortified with microencapsulated L-5-methyltetrahydrofolic acid or equimolar folic acid increase blood folate concentrations to a similar extent in healthy men and women. PubMed: Microencapsulation of L-5-methyltetrahydrofolic acid with ascorbate improves stability in baked bread products. PubMed: Stability evaluation of freeze-dried Lactobacillus paracasei subsp. tolerance and Lactobacillus delbrueckii subsp. bulgaricus in oral capsules. PubMed: Dog rose (Rosa canina L.) as a functional ingredient in porcine frankfurters without added sodium ascorbate and sodium nitrite. PubMed: Effects of anticaking agents and relative humidity on the physical and chemical stability of powdered vitamin C. PubMed: Thermal oxidation studies on reduced folate, L-5-methyltetrahydrofolic acid (L-5-MTHF) and strategies for stabilization using food matrices. PubMed: Effect of sodium ascorbate dose on the shelf life stability of reduced nitrite liver pâtés. PubMed: Use of fluorogenic probes to differentiate between hydrophilic and lipophilic antioxidant activity in a fish cell line. PubMed: Tocopherol and ascorbate have contrasting effects on the viability of microencapsulated Lactobacillus rhamnosus GG. PubMed: Determination of carbendazim, thiophanate, thiophanate-methyl and benomyl residues in agricultural products by liquid chromatography-tandem mass spectrometry. PubMed: Edible mushroom (Flammulina velutipes) extract inhibits melanosis in Kuruma shrimp (Marsupenaeus japonicus). PubMed: Iron regulates the uptake of ascorbic acid and the expression of sodium-dependent vitamin C transporter 1 (SVCT1) in human intestinal Caco-2 cells. PubMed: Value-added use of mushroom ergothioneine as a colour stabilizer in processed fish meats. PubMed: The effect of lutein, sesamol, ellagic acid and olive leaf extract on lipid oxidation and oxymyoglobin oxidation in bovine and porcine muscle model systems. PubMed: Influence of simultaneous variations in temperature and relative humidity on chemical stability of two vitamin C forms and implications for shelf life models. PubMed: Study of the lactic acid bacteria throughout the manufacture of dry-cured lacón (a Spanish traditional meat product). Effect of some additives. PubMed: Effectiveness of a large-scale iron-fortified milk distribution program on anemia and iron deficiency in low-income young children in Mexico. PubMed: Storage stability of freeze-dried Lactobacillus acidophilus (La-5) in relation to water activity and presence of oxygen and ascorbate. PubMed: Application of multivariate analysis to the effects of additives on chemical and sensory quality of stored coffee brew. PubMed: Physicochemical properties, and antioxidant and antimicrobial effects of garlic and onion powder in fresh pork belly and loin during refrigerated storage. PubMed: Progress in herbicide determination with the thylakoid bioassay. PubMed: Effect of Indian herbal hypoglycemic agents on antioxidant capacity and trace elements content in diabetic rats. PubMed: Impact of deliquescence on the chemical stability of vitamins B1, B6, and C in powder blends. PubMed: Influence of various preservatives on the quality of minced beef under modified atmosphere at chilled storage. PubMed: Ascorbate, green tea and grape seed extracts increase the shelf life of low sulphite beef patties. PubMed: Improved methods for the preparation of [3H]folate polyglutamates: biosynthesis with Lactobacillus casei and enzymatic synthesis with Escherichia coli folylpolyglutamate synthetase. PubMed: Sodium ascorbate inhibits growth via the induction of cell cycle arrest and apoptosis in human malignant melanoma A375.S2 cells. PubMed: Application of electron spin resonance spectroscopy and spin probes to investigate the effect of ingredients on changes in wheat dough during heating. PubMed: Final report of the safety assessment of L-Ascorbic Acid, Calcium Ascorbate, Magnesium Ascorbate, Magnesium Ascorbyl Phosphate, Sodium Ascorbate, and Sodium Ascorbyl Phosphate as used in cosmetics. PubMed: Mechanism of oxymyoglobin oxidation in the presence of oxidizing lipids in bovine muscle. PubMed: The effect of selected functional additives and heat treatment on nitrosamine content in pasteurized pork ham. PubMed: Formulations of controlled atmosphere agents for packaged foods. PubMed: Lack of promotion of urinary bladder carcinogenesis by sodium bicarbonate and/or L-ascorbic acid in male ODS/Shi-od/od rats synthesizing alpha 2 mu-globulin but not L-ascorbic acid. PubMed: Comparison of vitamin C bioavailability after multiple or single oral dosing of different formulations in sheep. PubMed: Enzymatic deconjugation of erythrocyte polyglutamyl folates during preparation for folate assay: investigation with reversed-phase liquid chromatography. PubMed: Effect of vitamin C concentration and co-injection with calcium chloride on beef retail display color. PubMed: Antioxidant effect of vitamin E and glutathione on lipid peroxidation in boar semen plasma. PubMed: Growth of Listeria monocytogenes on vacuum-packed cooked meats: effects of pH, aw, nitrite and ascorbate. PubMed: [Effect of preservatives on survival of Campylobacter jejuni in ground pork meat]. PubMed: An investigation of the antibacterial effect of carrot on Listeria monocytogenes. PubMed: Ascorbate in the treatment of experimental transplanted melanoma. PubMed: Inhibitory effects of Maharishi-4 and Maharishi-5 on microsomal lipid peroxidation. PubMed: Participation of urinary Na+, K+, pH, and L-ascorbic acid in the proliferative response of the bladder epithelium after the oral administration of various salts and/or ascorbic acid to rats. PubMed: Various sodium salts, potassium salts, a calcium salt and an ammonium salt induced ornithine decarboxylase and stimulated DNA synthesis in rat stomach mucosa. PubMed: Nutritional value and safety in mice of proteins and their admixtures with carbohydrates and vitamin C after heating. PubMed: Studies on antioxidants: their carcinogenic and modifying effects on chemical carcinogenesis. PubMed: Effect of ascorbic acid on plasma calcium in guinea pigs. PubMed: Drugs, food additives and natural products as promoters in rat urinary bladder carcinogenesis. PubMed: Methylation of liver DNA of rat and mouse by N-nitrosodimethylamine formed in vivo from dimethylamine and nitrite. PubMed: Promoting effects of various chemicals in rat urinary bladder carcinogenesis initiated by N-nitroso-n-butyl-(4-hydroxybutyl)amine. PubMed: Reduction of teratogenic effects of ethylenethiourea in rats by interaction with sodium nitrite in vivo. PubMed: [Ascorbic acid and cancer of the duodenum. An experimental study (author's transl)]. PubMed: [Storage stability of Guelders smoked sausage (Gelderse rookworst) containing 20 per cent mechanically processed pork (author's transl)]. PubMed: Cell culture tumor promotion experiments with saccharin, phorbol myristate acetate and several common food materials. PubMed: [Blockade of nitrogen oxide and nitrites by various substances]. PubMed: Dietary and other factors affecting nitrosomethylurea (NMU) formation in the rat stomach. PubMed: Studies related to nitrosamide formation: nitrosation in solvent: water and solvent systems, nitrosomethylurea formation in the rat stomach and analysis of a fish product for ureas. PubMed: Effect of sodium ascorbate on tumor induction in rats treated with morpholine and sodium nitrite, and with nitrosomorpholine. PubMed: Rapid screening procedure for the determination of preservatives in ground beef: sulfites, benzoates, sorbates, and ascorbates. PubMed: [Nitrosamines. Review]. PubMed: Induction of mouse lung adenomas by amines or ureas plus nitrite and by N-nitroso compounds: effect of ascorbate, gallic acid, thiocyanate, and caffeine. PubMed: Pre-slaughter injection of sodium ascorbate as a method of inhibiting metmyoglobin formation in fresh beef. PubMed: Effect of sodium ascorbate and sodium nitrite on toxin formation of Clostridium botulinum in wieners.