laevo-citrulline

delta-ureidonorvaline

CAS: 372-75-8 C6 H13 N3 O3 MW: 175.18821000

Identification

Namelaevo-citrulline
CAS Number372-75-8
EINECS206-759-6
FDA UNII29VT07BGDA
Molecular FormulaC6 H13 N3 O3
Molecular Weight175.18821000
MDL NumberMFCD00064397
Nikkaji NumberJ5.711H
Beilstein1725416
XlogP3-4.30 (est)

Regulatory

Physical Properties

Appearance white powder (est)
Assay 95.00 to 100.00
Food Chemicals Codex Listed No
Melting Point 235.50 °C. @ 760.00 mm Hg
Boiling Point 386.00 to 387.00 °C. @ 760.00 mm Hg (est)
Flash Point 370.00 °F. TCC ( 187.70 °C. ) (est)
logP (o/w) -3.190
Soluble in water, 1.283e+004 mg/L @ 25 °C (est)

Cosmetic Information

CosIngcosmetic data
Cosmetic Usesskin conditioning

No sensory data available

Safety Information

Preferred SDSView
Oral/Parenteral ToxicityNot determined
Dermal ToxicityNot determined
Inhalation ToxicityNot determined

GHS Classification

['GHS Classification in accordance with 29 CFR 1910 (OSHA HCS)', 'GHS Label elements, including precautionary statements']

Safety in Use

Categoryspecial dietary and nutritional additives
Recommendation for laevo-citrulline usage levels up tonot for fragrance use.
Recommendation for laevo-citrulline flavor usage levels up tonot for flavor use.

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Potential Uses

biological additives

Natural Occurrence

apple custard apple fruit cantaloupe fruit chayote plant cucumber fruit garlic bulb irish moss thallus PMC melon bitter melon fruit sesame soursop plant watermelon fruit

Synonyms

(S)-2- amino-5-(aminocarbonyl)aminopentanoic acid (2S)-2- amino-5-(aminocarbonylamino)pentanoic acid (2S)-2- amino-5-(carbamoylamino)pentanoic acid L-2- amino-5-ureido-valeric acid (S)-2- amino-5-ureidopentanoic acid L(+)-2- amino-5-ureidovaleric acid alpha- amino-delta-ureidovaleric acid N5-( aminocarbonyl)-L-Ornithine N5-( aminocarbonyl)-laevo-Ornithine N5- carbamoyl-L-ornithine L-N5- carbamoyl-ornithine citrulline L- citrulline L- ornithine, N5-(aminocarbonyl)- delta- ureidonorvaline PubMed: L-citrulline Improves Splanchnic Perfusion and Reduces Gut Injury during Exercise. PubMed: Effects of Watermelon Supplementation on Aortic Hemodynamic Responses to the Cold Pressor Test in Obese Hypertensive Adults. PubMed: Watermelon juice: potential functional drink for sore muscle relief in athletes. PubMed: Effects of watermelon supplementation on arterial stiffness and wave reflection amplitude in postmenopausal women. PubMed: Watermelon extract supplementation reduces ankle blood pressure and carotid augmentation index in obese adults with prehypertension or hypertension. PubMed: Effects of leucine and citrulline versus non-essential amino acids on muscle protein synthesis in fasted rat: a common activation pathway? PubMed: The effect of L-citrulline ingestion on ECG QT interval and autonomic nervous system activity. PubMed: Effects of watermelon supplementation on aortic blood pressure and wave reflection in individuals with prehypertension: a pilot study. PubMed: A Maillard reaction product enhances eNOS activity in human endothelial cells. PubMed: Oral L-citrulline supplementation attenuates blood pressure response to cold pressor test in young men. PubMed: Norfuraneol dephosphorylates eNOS at threonine 495 and enhances eNOS activity in human endothelial cells. PubMed: Dietary supplementation with watermelon pomace juice enhances arginine availability and ameliorates the metabolic syndrome in Zucker diabetic fatty rats. PubMed: L-citrulline recycling by argininosuccinate synthetase and lyase in rat gastric fundus. PubMed: Identification of coumarins from lemon fruit (Citrus limon) as inhibitors of in vitro tumor promotion and superoxide and nitric oxide generation. PubMed: Spontaneous occurrence of hepatic lipidosis in a group of laboratory cats. PubMed: Oral administration of arginine and citrulline in the treatment of lysinuric protein intolerance. PubMed: Formation of N-nitrosoproline by reacting nitrite with L-citrulline and L-arginine.