laevo-lysine hydrochloride

L-(+)-lysine monohydrochloride

CAS: 657-27-2 C6 H15 N2 O2 Cl MW: 182.64995000

Identification

Namelaevo-lysine hydrochloride
CAS Number657-27-2
EINECS211-519-9
FDA UNIIJNJ23Q2COM
Molecular FormulaC6 H15 N2 O2 Cl
Molecular Weight182.64995000
MDL NumberMFCD00064564
Beilstein3563889

Regulatory

FDA/DG SANTE Petitions, Reviews, NoticesGRN 414
DG SANTE Food Flavourings17.031 L-(+)-lysine monohydrochloride
FDA Mainterm (SATF)L-Lysine Monohydrochloride
FDA RegulationFDA PART 172 -- FOOD ADDITIVES PERMITTED FOR DIRECT ADDITION TO FOOD FOR HUMAN CONSUMPTION

Physical Properties

Appearance white powder (est)
Assay 98.50 to 100.00
Food Chemicals Codex Listed No
Melting Point 261.00 to 263.00 °C. @ 760.00 mm Hg
Boiling Point 311.50 °C. @ 760.00 mm Hg (est)
Vapor Pressure 0.000123 mmHg @ 25.00 °C. (est)
Flash Point 288.00 °F. TCC ( 142.22 °C. )
logP (o/w) -1.036 (est)
Soluble in alcohol

Cosmetic Information

CosIng['cosmetic data2', 'cosmetic data']
Cosmetic Usesantioxidants

No sensory data available

Safety Information

Preferred SDSView
European informationMost important hazard(s):
Oral/Parenteral Toxicityintraperitoneal-rat LD50 4019 mg/kg
Dermal ToxicityNot determined
Inhalation ToxicityNot determined

GHS Classification

['GHS Classification in accordance with 29 CFR 1910 (OSHA HCS)', 'GHS Label elements, including precautionary statements', 'BEHAVIORAL: ATAXIA\nBEHAVIORAL: ALTERED SLEEP TIME (INCLUDING CHANGE IN RIGHTING REFLEX)\nLUNGS, THORAX, OR RESPIRATION: DYSPNEA']

Safety in Use

Categoryspecial dietary and nutritional additives
Recommendation for laevo-lysine hydrochloride usage levels up tonot for fragrance use.
Maximised Survey-derived Daily Intakes (MSDI-EU)30.00 (μg/capita/day)
Modified Theoretical Added Maximum Daily Intake (mTAMDI)23000 (μg/person/day)
Threshold of Concern1800 (μg/person/day)
Structure ClassI
Dairy products, excluding products of category 02.0 (01.0)-
Fats and oils, and fat emulsions (type water-in-oil) (02.0)-
Edible ices, including sherbet and sorbet (03.0)-
Processed fruit (04.1)-
Processed vegetables (incl. mushrooms & fungi, roots & tubers, pulses and legumes), and nuts & seeds (04.2)-
Confectionery (05.0)-
Chewing gum (05.3)-
Cereals and cereal products, incl. flours & starches from roots & tubers, pulses & legumes, excluding bakery (06.0)-
Bakery wares (07.0)-
Meat and meat products, including poultry and game (08.0)-
Fish and fish products, including molluscs, crustaceans and echinoderms (MCE) (09.0)-
Eggs and egg products (10.0)-
Sweeteners, including honey (11.0)-
Salts, spices, soups, sauces, salads, protein products, etc. (12.0)-
Foodstuffs intended for particular nutritional uses (13.0)-
Non-alcoholic ("soft") beverages, excl. dairy products (14.1)70.00000
Alcoholic beverages, incl. alcohol-free and low-alcoholic counterparts (14.2)-
Ready-to-eat savouries (15.0)-
Composite foods (e.g. casseroles, meat pies, mincemeat) - foods that could not be placed in categories 01.0 - 15.0 (16.0)-

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Potential Uses

antioxidants reducing agents skin conditioning

Natural Occurrence

found in nature

Synonyms

darvyl (2S)-2,6- diaminohexanoic acid hydrochloride (S)-2,6- diaminohexanoic acid monohydrochloride enisyl lyamine L- lysine chlorhydrate L- lysine HCl lysine hydrochloride L-mono lysine hydrochloride laevo- lysine hydrochloride L- lysine hydrochloride (1:1) L- lysine mono hydrochloride L- lysine monohydrochloride L-(+)- lysine monohydrochloride laevo- lysine monohydrochloride L- lysine, hydrochloride L- lysine, hydrochloride (1:1) L- lysine, monohydrochloride lysine, monohydrochloride, L- L- lysinehydrochloride lysion PubMed: Studies on the effect of polymer coating on solution grown hygroscopic non-linear optical single crystal of L-lysine monohydrochloride. PubMed: Effects of L-lysine monohydrochloride on insulin and blood glucose levels in spinal cord injured rats. PubMed: Probes on L-lysine monohydrochloride dihydrate: a semiorganic nonlinear optical crystal. PubMed: Hemolysate-filled polyethyleneimine and polyurea microcapsules as potential red blood cell substitutes: effect of aqueous monomer type on properties of the prepared microcapsules. PubMed: Plasticity and slip system of plate-shaped crystals of L-lysine monohydrochloride dihydrate. PubMed: Influence of elastic deformation of particles on Heckel analysis. PubMed: Adverse effects of excess lysine in calves. PubMed: Influence of crystal shape on the tableting performance of L-lysine monohydrochloride dihydrate. PubMed: Effects of initial particle size on the tableting properties of L-lysine monohydrochloride dihydrate powder. PubMed: Methionine imbalance and toxicity in calves. PubMed: Influence of crystal habit on the surface free energy and interparticulate bonding of L-lysine monohydrochloride dihydrate. PubMed: Adverse effects of excess DL-methionine in calves with different body weights. PubMed: Neuroprotective effect of L-lysine monohydrochloride on acute iterative anoxia in rats with quantitative analysis of electrocorticogram. PubMed: Absence of limiting amino acids in calves fed a corn and soybean meal diet past three months of age. PubMed: Superior preservation of the staphylococcal glycocalyx with aldehyde-ruthenium red and select lysine salts using extended fixation times. PubMed: Limiting amino acids for a corn and soybean meal diet in weaned calves less than three months of age. PubMed: Lysine deficiency in postweaned calves fed corn and corn gluten meal diets. PubMed: The metabolic roles, pharmacology, and toxicology of lysine. PubMed: Lysine supplementation of cereal foods: a retrospective. PubMed: Effect of Na and Cl infusion on loop function and plasma renin activity in rats. PubMed: Effect of L-lysine monohydrochloride on cutaneous herpes simplex virus in the guinea pig. PubMed: [The efficiency of and requirements for selected amino acids in growing female pigs. 3. Threonine]. PubMed: Success of L-lysine therapy in frequently recurrent herpes simplex infection. Treatment and prophylaxis. PubMed: Inhibitory effect of intravenous lysine infusion on urea cycle metabolism. PubMed: The bioavailability of supplementary lysine and its effect on the energy and nitrogen excretion of adult cockerels fed diets diluted with cellulose. PubMed: Treatment of recurrent herpes simplex infections with L-lysine monohydrochloride. PubMed: Lysine prophylaxis in recurrent herpes simplex labialis: a double-blind, controlled crossover study. PubMed: Bicarbonaturic effect of lysine in the dog. PubMed: [Utilization of LIN (lysine-indole-motility) medium for the preliminary identification of enteropathogenic bacteria]. PubMed: Utility of fasting essential amino acid plasma levels in formulation of nutritionally adequate diets IV: lowering of human plasma cholesterol and triglyceride levels by lysine and tryptophan supplementation. PubMed: [On the effect of L-lysine-monohydrochloride on the survival time of bilaterally nephrectomized rats]. PubMed: EFFECT OF L-LYSINE MONOHYDROCHLORIDE UPON UREA FORMATION IN TWO PATIENTS WITH CHRONIC RENAL FAILURE. PubMed: Resistant edema treated with L-lysine monohydrochloride. PubMed: L-lysine monohydrochloride. A clinical study of its action as a chloruretic acidifying adjuvant to mercurial diuretics. PubMed: The effects of the ingestion of amino acid on gastric secretion, with particular reference to L-lysine monohydrochloride.