laevo-erythritol

L-threitol

CAS: 2319-57-5 C4 H10 O4 MW: 122.12050000

Identification

Namelaevo-erythritol
CAS Number2319-57-5
FDA UNIISearch
Molecular FormulaC4 H10 O4
Molecular Weight122.12050000
MDL NumberMFCD00064294
Nikkaji NumberJ232.139D
Beilstein1719754
XlogP3-2.30 (est)

Regulatory

Physical Properties

Assay 95.00 to 100.00
Food Chemicals Codex Listed No
Soluble in water, 1e+006 mg/L @ 25 °C (est)

No sensory data available

Safety Information

Preferred SDSView
Oral/Parenteral ToxicityNot determined
Dermal ToxicityNot determined
Inhalation ToxicityNot determined

GHS Classification

['GHS Classification in accordance with 29 CFR 1910 (OSHA HCS)', 'GHS Label elements, including precautionary statements']

Safety in Use

Categoryinformation only not used for fragrances or flavors
Recommendation for laevo-erythritol usage levels up tonot for fragrance use.
Recommendation for laevo-erythritol flavor usage levels up tonot for flavor use.

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Potential Uses

None Found

Natural Occurrence

not found in nature

Synonyms

(2S,3S)- butane-1,2,3,4-tetrol laevo- butane-1,2,3,4-tetrol L-1,2,3,4- butanetetraol (2S,3S)-1,2,3,4- butanetetrol (S-(R*,R*))-1,2,3,4- butanetetrol laevo-1,2,3,4- butanetetrol 1,2,3,4- butanetetrol, (2S,3S)- L- erythritol L- threitol laevo- threitol PubMed: Recent developments and future prospects on bio-based polyesters derived from renewable resources: A review. PubMed: Development and Validation of a High Pressure Liquid Chromatography-UV Method for the Determination of Treosulfan and Its Epoxy Metabolites in Human Plasma and Its Application in Pharmacokinetic Studies. PubMed: Controlled co-delivery nanocarriers based on mixed micelles formed from cyclodextrin-conjugated and cross-linked copolymers. PubMed: Searching for combinations of small-molecule correctors to restore f508del-cystic fibrosis transmembrane conductance regulator function and processing. PubMed: Alditols and monosaccharides from sorghum vinegar can attenuate platelet aggregation by inhibiting cyclooxygenase-1 and thromboxane-A2 synthase. PubMed: The 1,3-dipolar cycloaddition reaction of chiral carbohydrate-derived nitrone and olefin: towards long-chain sugars. PubMed: 2-methyl-L-erythritol glycosides from Gardenia jasminoides. PubMed: Treosulfan-based conditioning before hematopoietic SCT: more than a BU look-alike. PubMed: Alternating oligo[(2,3-O-isopropylidene-L-threitol)]-co-[(E,E)-1,4-bis(styryl)benzene]s: the linear chirality transmission additivity relationship in nematic liquid crystals. PubMed: Novel generation of pH indicators for proton magnetic resonance spectroscopic imaging. PubMed: Treatment of active secondary progressive multiple sclerosis with treosulfan. PubMed: Synthesis of a salacinol analogue and its alpha-glucosidase inhibitory activity. PubMed: Generation of an antibody specific to erythritol, a non-immunogenic food additive. PubMed: Enthalpy of sublimation in the study of the solid state of organic compounds. Application to erythritol and threitol. PubMed: Attempted synthesis of 2-acetamido and 2-amino derivatives of salacinol. Ring opening reactions. PubMed: Determination of the enthalpy of solute-solvent interaction from the enthalpy of solution: aqueous solutions of erythritol and L-threitol. PubMed: Towards carbohydrate derivatives of the ReI(CO)3 fragment. PubMed: Synthesis of D-lyxitol and D-ribitol analogues of the naturally occurring glycosidase inhibitor salacinol. PubMed: Conformational study of erythritol and threitol in the gas state by density functional theory calculations. PubMed: Inhibition of the Escherichia coli RecA protein: zinc(II), copper(II) and mercury(II) trap RecA as inactive aggregates. PubMed: Addition of treosulfan to a nonmyeloablative conditioning regimen results in enhanced chimerism and immunologic tolerance in an experimental allogeneic bone marrow transplant model. PubMed: Action of treosulfan in myelin-oligodendrocyte-glycoprotein-induced experimental autoimmune encephalomyelitis and human lymphocytes. PubMed: Aromatic compound glucosides, alkyl glucoside and glucide from the fruit of anise. PubMed: Antileukaemic activity of treosulfan in xenografted human acute lymphoblastic leukaemias (ALL). PubMed: Site-specific hydroxylation at polyguanosine in double-stranded DNA by nickel(II) in the presence of SH compounds: comparison with singlet oxygen-induced DNA damage. PubMed: Saccharide Libraries as Potential Templates for Regio- and Chiroselective Introduction of Two Functional Groups into [60]Fullerene. PubMed: Synthesis of 2-C-methyl-D-erythritol and 2-C-methyl-L-threitol; determination of the absolute configuration of 2-C-methyl-1,2,3,4-butanetetrol isolated. PubMed: Purification and characterization of a NAD+-dependent sorbitol dehydrogenase from Japanese pear fruit. PubMed: Investigation of bioavailability and pharmacokinetics of treosulfan capsules in patients with relapsed ovarian cancer. PubMed: Asymmetric synthesis of axially chiral biaryls via desymmetrization of 2,2',6,6'-tetrahydroxybiphenyl using 1,4-Di-O-benzyl-L-threitol as a chiral template PubMed: DNA alkylation and interstrand cross-linking by treosulfan. PubMed: The alkylator treosulfan shows activity towards human renal-cell carcinoma in vivo and in vitro. PubMed: Clinical pharmacokinetics of intravenous treosulfan in patients with advanced solid tumors. PubMed: Stimulation of biosynthetic activity by novel succinate esters in rat pancreatic islets. PubMed: Reversible inhibition of sheep liver sorbitol dehydrogenase by thiol compounds. PubMed: Studies on L-threose as substrate for aldose reductase: a possible role in preventing protein glycation. PubMed: Combination effects of poly(ADP-ribose) polymerase inhibitors and DNA-damaging agents in ovarian tumor cell lines--with special reference to cisplatin. PubMed: Antitumor activity of treosulfan in human lung carcinomas. PubMed: Evidence for a glycerol pathway through aquaporin 1 (CHIP28) channels. PubMed: Ascorbic acid glycation: the reactions of L-threose in lens tissue. PubMed: The crystal structure of D-threitol at 119 K and 198 K. PubMed: Antitumor activity of treosulfan against human breast carcinomas. PubMed: Inhibition of the alpha-L-arabinofuranosidase III of Monilinia fructigena by 1,4-dideoxy-1,4-imino-L-threitol and 1,4-dideoxy-1,4-imino-L-arabinitol. PubMed: Purification and characterization of human liver sorbitol dehydrogenase. PubMed: Contraction of guinea-pig lung parenchymal strips by substance P and related peptides. PubMed: Biosynthesis of novel acidic phospholipid analogs in Escherichia coli. PubMed: The effect of substance P and related peptides on the guinea-pig lung strip. PubMed: New type bifunctional nitrosoureido derivatives with cytostatic activity. PubMed: Detection and characterization of sorbitol dehydrogenase from apple callus tissue. PubMed: Induction of chromosomal aberrations and mutations with isomeric forms of L-threitol-I,4-bismethanesulfonate in plant materials. PubMed: Compounds derived from L-threitol 1,4-bismethanesulfonate. PubMed: IDENTIFICATION OF ALTRO-HEPTULOSE AND L-THREITOL AS PRODUCTS OF MESO-ERYTHRITOL OXIDATION BY ACETOBACTER SUBOXYDANS. PubMed: [ANALYSIS OF THE EFFECTS OF L-THREITOL-1,4-BISMETHANESULFONATE ON THE CHROMOSOMES OF VICIA FABA L]. PubMed: L-Threitol dimethanesulfonate. PubMed: Biochemistry of the wood-rotting fungi: 5. The production of d-threitol (l-erythritol) by Armillaria mellea (Vahl) Quélet.