laevo-threonine
L-threonine
Identification
| Name | laevo-threonine |
| CAS Number | 72-19-5 |
| EINECS | 200-774-1 |
| FDA UNII | 2ZD004190S |
| Molecular Formula | C4 H9 N O3 |
| Molecular Weight | 119.12033000 |
| MDL Number | MFCD00064270 |
| Nikkaji Number | J21.883I |
| Beilstein | 1721646 |
| XlogP3 | -2.90 (est) |
Regulatory
| JECFA Food Flavoring | 2119 L-threonine |
| FEMA Number | 4710 |
| FDA | No longer provide for the use of these seven synthetic flavoring substances |
| FDA Mainterm (SATF) | 72-19-5 ; L-THREONINE |
| FDA Regulation | FDA PART 172 -- FOOD ADDITIVES PERMITTED FOR DIRECT ADDITION TO FOOD FOR HUMAN CONSUMPTION |
Physical Properties
| Appearance | white crystalline powder (est) |
| Assay | 98.00 to 100.00 |
| Food Chemicals Codex Listed | No |
| Melting Point | 256.00 to 272.00 °C. @ 760.00 mm Hg |
| Flash Point | 325.00 °F. TCC ( 162.90 °C. ) (est) |
| logP (o/w) | -2.940 |
| Soluble in | water, 2.79e+005 mg/L @ 25 °C (est) |
Cosmetic Information
| CosIng | cosmetic data |
| Cosmetic Uses | antistatic agents |
Organoleptic Properties
| Odor Description | ADM L-Threonine is a high quality product specifically designed for the feed industry. Produced from advanced technology, ADM L-Threonine is composed of 100% isomerically pure L-Threonine, which translates into 100% bioavailability for swine, poultry, and other animals. |
| Taste Description | sweet |
Safety Information
| Preferred SDS | View |
| European information | Most important hazard(s): |
| Oral/Parenteral Toxicity | intraperitoneal-rat LD50 3098 mg/kg |
| Dermal Toxicity | Not determined |
| Inhalation Toxicity | Not determined |
GHS Classification
['GHS Classification in accordance with 29 CFR 1910 (OSHA HCS)', 'GHS Label elements, including precautionary statements']
Safety in Use
| Category | special dietary and nutritional additives |
| Recommendation for laevo-threonine usage levels up to | not for fragrance use. |
| baked goods | 50.00000 |
| beverages(nonalcoholic) | 50.00000 |
| beverages(alcoholic) | 50.00000 |
| breakfast cereal | 50.00000 |
| cheese | 50.00000 |
| chewing gum | 50.00000 |
| condiments / relishes | 50.00000 |
| confectionery froastings | 50.00000 |
| egg products | 50.00000 |
| fats / oils | 50.00000 |
| fish products | 50.00000 |
| frozen dairy | 50.00000 |
| fruit ices | 50.00000 |
| gelatins / puddings | 50.00000 |
| granulated sugar | 50.00000 |
| gravies | 50.00000 |
| hard candy | 50.00000 |
| imitation dairy | 50.00000 |
| instant coffee / tea | 50.00000 |
| jams / jellies | 50.00000 |
| meat products | 50.00000 |
| milk products | 50.00000 |
| nut products | 50.00000 |
| other grains | 50.00000 |
| poultry | 50.00000 |
| processed fruits | 50.00000 |
| processed vegetables | 50.00000 |
| reconstituted vegetables | 50.00000 |
| seasonings / flavors | 50000.00000 |
| snack foods | 50.00000 |
| soft candy | 50.00000 |
| soups | 50.00000 |
| sugar substitutes | 50.00000 |
| sweet sauces | 50.00000 |
BOC Sciences
Best of Chemicals Supplier
Quality supplier of research chemicals and biochemicals including inhibitors, building blocks, GMP Products, impurities and metabolites, APIs for Veterinary, Natural Compounds, ADCs, Stem Cell Molecul...
Charkit Chemical Corporation
The Specialty Chemical Specialists
Explore this website to discover the products and services that Charkit provides for your industry and please contact us directly to find out how we can be of service to you.
Glentham Life Sciences Ltd
The Chemical, Biochemical & Research Essentials Supplier
Glentham Life Sciences is a supplier of fine chemicals and raw materials with warehousing, laboratories and packaging facilities in the UK.
OQEMA
With a focus on providing the highest level of service
OQEMA has established itself at the forefront of the global chemical industry.
Penta International Corporation
Chemistry innovation
At Penta, our products and services help businesses do business better.
Qingdao Free Trade Zone United International Co Ltd
Quality Products
A partner in your supply chain solution.
Potential Uses
Natural Occurrence
Synonyms
ajipure threonine
(2S,3R)-2-
amino-3-hydroxybutanoic acid
(R-(R*,S*))-2-
amino-3-hydroxybutanoic acid
[R-(R*,S*)]-2-
amino-3-hydroxybutanoic acid
2-
amino-3-hydroxybutanoic acid, (R-(R*,S*))-
(2S,3R)-2-
amino-3-hydroxybutyric acid
L-2-
amino-3-hydroxybutyric acid
butanoic acid, 2-amino-3-hydroxy-, (R-(R*,S*))-
L-
threonin
(2S,3R)-
threonine
(2S,3R)-(-)-
threonine
(S)-
threonine
L-
threonine
L-(-)-
threonine
PubMed:
Biotechnological production of amino acids and derivatives: current status and prospects.
Leffingwell & Associates:
Flavor Properties of FEMA GRAS List 25 flavor chemicals
PubMed:
The effects of glycine, L-threonine, and L-cystine supplementation to a 9% casein diet on the conversions of L-tryptophan to nicotinamide and to serotonin in rats.
PubMed:
The role of ACT-like subdomain in bacterial threonine dehydratases.
PubMed:
Molecular evolution of threonine dehydratase in bacteria.
PubMed:
Campylobacter jejuni pdxA affects flagellum-mediated motility to alter host colonization.
PubMed:
Effect of metformin on the urinary metabolites of diet-induced-obese mice studied by ultra performance liquid chromatography coupled to time-of-flight mass spectrometry (UPLC-TOF/MS).
PubMed:
Leucine is essential for attenuating fetal growth restriction caused by a protein-restricted diet in rats.
PubMed:
Optimal production of L-threo-2,3-dihydroxyphenylserine (L-threo-DOPS) on a large scale by diastereoselectivity-enhanced variant of L-threonine aldolase expressed in Escherichia coli.
PubMed:
Draft genome sequence of Escherichia coli XH001, a producer of L-threonine in industry.
PubMed:
Dietary self-selection of protein-unbalanced diets supplemented with three essential amino acids in Nile tilapia.
PubMed:
Gelatin enhances 2-keto-L-gulonic acid production based on Ketogulonigenium vulgare genome annotation.
PubMed:
Metabolic engineering of Escherichia coli and Corynebacterium glutamicum for the production of L-threonine.
PubMed:
The effect of the combination of reducing and oxidising agents on the viscoelastic properties of dough and sensory characteristics of buns.
PubMed:
Metabolic pathways and fermentative production of L-aspartate family amino acids.
PubMed:
Safety assessment of N-acetyl-L-threonine.
PubMed:
Construction of a novel shuttle vector for use in Brevibacterium flavum, an industrial amino acid producer.
PubMed:
Enhanced synthesis of L-threo-3,4-dihydroxyphenylserine by high-density whole-cell biocatalyst of recombinant L-threonine aldolase from Streptomyces avelmitilis.
PubMed:
Molecular analysis of the Salmonella typhimurium tdc operon regulation.
PubMed:
Allelic variation of the Tas1r3 taste receptor gene selectively affects taste responses to sweeteners: evidence from 129.B6-Tas1r3 congenic mice.
PubMed:
Amino acid and carbohydrate preferences in C57BL/6ByJ and 129P3/J mice.
PubMed:
Nitrogen-fixing and cellulose-producing Gluconacetobacter kombuchae sp. nov., isolated from Kombucha tea.
PubMed:
On-column coaxial flow chemiluminescence detection for underivatized amino acids by pressurized capillary electrochromatography using a monolithic column.
PubMed:
Improved L-threonine production of Escherichia coli mutant by optimization of culture conditions.
PubMed:
Characterization of germination receptors of Bacillus cereus ATCC 14579.
PubMed:
Regulation of aspartokinase, aspartate semialdehyde dehydrogenase, dihydrodipicolinate synthase and dihydrodipicolinate reductase in Lactobacillus plantarum.
PubMed:
Effect of adding dietary L-lysine, L-threonine and L-methionine to a low gluten diet on urea synthesis in rats.
PubMed:
Pseudoalteromonas sagamiensis sp. nov., a marine bacterium that produces protease inhibitors.
PubMed:
Industrial production of amino acids by coryneform bacteria.
PubMed:
Metabolic engineering of acetaldehyde production by Streptococcus thermophilus.
PubMed:
Chlorosis-inducing products from Pseudomonas syringae pathovars: new N-coronafacoyl compounds.
PubMed:
Changes in nitrogen compounds in must and wine during fermentation and biological aging by flor yeasts.
PubMed:
The effects of tannins on nutrient utilisation in the White Pekin duck.
PubMed:
Effect of amino acids on the composition and properties of extruded mixtures of wheat flour and glucose.
PubMed:
Origin of acetaldehyde during milk fermentation using (13)C-labeled precursors.
PubMed:
Time course and pattern of compensatory ingestive behavioral adjustments to lysine deficiency in rats.
PubMed:
Vicinal diketone formation in yogurt: (13)C precursors and effect of branched-chain amino acids.
PubMed:
Pyrazine formation from serine and threonine.
PubMed:
L-threonine injection into PPC modifies food intake, lateral hypothalamic activity, and sympathetic discharge.
PubMed:
Dietary protein and amino acid levels alter threonine dehydrogenase activity in hepatic mitochondria of Gallus domesticus.
PubMed:
Crystalline lysine and threonine supplementation of soft red winter wheat or triticale, low-protein diets for growing-finishing swine.
PubMed:
Response of rainbow trout (Oncorhynchus mykiss) growing from 50 to 170 g to supplements of either L-arginine or L-threonine in a semipurified diet.
PubMed:
Influence of high dietary threonine on growth and amino acids in blood and tissues of rats.
PubMed:
Anorexic action of a new potential neuropeptide Y antagonist [D-Tyr27,36, D-Thr32]-NPY (27-36) infused into the hypothalamus of the rat.
PubMed:
The addition of glutamic acid or protein to a threonine-deficient diet differentially affects growth performance and threonine dehydrogenase activity in fattening pigs.
PubMed:
Nutritional profile and antimicrobial spectrum of the spice Aframomum danielli K. Schum.
PubMed:
Timing and dose of amino acids injected into prepyriform cortex influence food intake.
PubMed:
Amino acid-supplemented raw soybean diets for finishing swine.
PubMed:
Performance and nutrient balance in growing swine fed low-protein diets supplemented with amino acids and potassium.
PubMed:
Behavior of L-threonine-degrading enzymes during liver regeneration.
PubMed:
Comparative effects of individual amino acid excesses when added to a corn-soybean meal diet: effects on growth and dietary choice in the chick.
PubMed:
Effect of excess levels of methionine, tryptophan, arginine, lysine or threonine on growth and dietary choice in the pig.
PubMed:
Amino acid excesses for young pigs: effects of excess methionine, tryptophan, threonine or leucine.
PubMed:
Weight gain, feed conversion efficiency and plasma free lysine as response criteria in evaluating supplements of lysine plus threonine and lysine plus tryptophan to deficient diets for rats.
PubMed:
Preparative resolution of D,L-threonine catalyzed by immobilized phosphatase.
PubMed:
Threonine metabolism of chicks fed threonine-imbalanced diets.
PubMed:
Fetal growth retardation induced by dietary imbalance of threonine and dispensable amino acids, with adequate energy and protein-equivalent intakes, in pregnant rats.
PubMed:
Protein quality, food intake and growth in normal and Walker 256 carcinosarcoma-bearing rats.
PubMed:
The amino acid supplementation of barley for the growing pig. 2. Optimal additions of lysine and threonine for growth.
PubMed:
Effect of diets supplemented with amino acids on intestinal sucrase and leucine aminopeptidase activities in rats.
PubMed:
Bioavailability of acetylated derivatives of methionine, threonine, and lysine.
PubMed:
Involvement of food intake in the lysine-arginine antagonism in chicks.