lactamide
propanamide, 2-hydroxy- (9CI)
Identification
| Name | lactamide |
| CAS Number | 2043-43-8 |
| EINECS | 218-049-3 |
| FDA UNII | 4JZP7XJN3O |
| Molecular Formula | C3 H7 N O2 |
| Molecular Weight | 89.09419000 |
| MDL Number | MFCD00008017 |
| Nikkaji Number | J1.792B |
Regulatory
Physical Properties
| Assay | 95.00 to 100.00 |
| Food Chemicals Codex Listed | No |
| Boiling Point | 281.93 °C. @ 760.00 mm Hg (est) |
| Flash Point | 256.00 °F. TCC ( 124.30 °C. ) (est) |
| logP (o/w) | -1.161 (est) |
| Soluble in | water, 7.82E+05 mg/L @ 25 °C (exp) |
Cosmetic Information
| CosIng | cosmetic data |
| Cosmetic Uses | skin conditioning |
No sensory data available
Safety Information
| Preferred SDS | View |
| Oral/Parenteral Toxicity | Not determined |
| Dermal Toxicity | Not determined |
| Inhalation Toxicity | Not determined |
GHS Classification
['GHS Classification in accordance with 29 CFR 1910 (OSHA HCS)', 'GHS Label elements, including precautionary statements']
Safety in Use
| Category | cosmetic agents |
| Recommendation for lactamide usage levels up to | not for fragrance use. |
| Recommendation for lactamide flavor usage levels up to | not for flavor use. |
Potential Uses
Natural Occurrence
Synonyms
2-
hydroxy-N-methyl-acetamide
2-
hydroxypropanamide
DL-
lactamide
DL-
lactic acid amide
propanamide, 2-hydroxy-
propanamide, 2-hydroxy- (9CI)
PubMed:
Acetamide hydrolyzing activity of Bacillus megaterium F-8 with bioremediation potential: optimization of production and reaction conditions.
PubMed:
Circular dichroism and optical rotation of lactamide and 2-aminopropanol in aqueous solution.
PubMed:
Parallel variable selection of molecular dynamics clusters as a tool for calculation of spectroscopic properties.
PubMed:
Isolation and characterization of Kluyvera georgiana strain with the potential for acrylamide biodegradation.
PubMed:
Correction of vibrational broadening in molecular dynamics clusters with the normal mode optimization method.
PubMed:
Biodegradation of acrylamide by Enterobacter aerogenes isolated from wastewater in Thailand.
PubMed:
Explicit versus implicit solvent modeling of Raman optical activity spectra.
PubMed:
High-throughput cocrystal slurry screening by use of in situ Raman microscopy and multi-well plate.
PubMed:
Using directed evolution to probe the substrate specificity of mandelamide hydrolase.
PubMed:
Antioxidant effect ofSalvia miltiorrhiza.
PubMed:
Growth phenotypes of Pseudomonas aeruginosa lasR mutants adapted to the airways of cystic fibrosis patients.
PubMed:
A novel thermostable nitrilase superfamily amidase from Geobacillus pallidus showing acyl transfer activity.
PubMed:
Comparison of glycerol, lactamide, acetamide and dimethylsulfoxide as cryoprotectants of Japanese white rabbit spermatozoa.
PubMed:
Reactions of pyrazolylborate-zinc-hydroxide complexes related to beta-lactamase activity.
PubMed:
Tris[(R)-lactamide-kappa2O,O']zinc(II) tetrabromozincate.
PubMed:
A new acylated quercetin glycoside from Ranunculus lanuginosus.
PubMed:
Contact allergy to cystamine bis-lactamide.
PubMed:
Poly(ethylenimine-co-L-lactamide-co-succinamide): a biodegradable polyethylenimine derivative with an advantageous pH-dependent hydrolytic degradation for gene delivery.
PubMed:
Structural adaptation to selective pressure for altered ligand specificity in the Pseudomonas aeruginosa amide receptor, amiC.
PubMed:
Human studies fail to detect the allergenic potential of cystamine bis-lactamide.
PubMed:
Novel antioxidants from roasted perilla seed.
PubMed:
Synthesis of beta-lactam antibiotics containing alpha-aminophenylacetyl group in the acyl moiety catalyzed by D-(-)-phenylglycyl-beta-lactamide amidohydrolase.
PubMed:
Isolation and characterization of catabolite repression control mutants of Pseudomonas aeruginosa PAO.
PubMed:
[Drug technology of a parenteral preparation for trimethoprim monotherapy].
PubMed:
Topical application of penetration enhancers to the skin of nude mice: a histopathological study.
PubMed:
Comparison of pancreatic exocrine secretion via endogenous secretin by intestinal infusion of hydrochloric acid and monocarboxylic acid in anesthetized piglets.
PubMed:
[Characteristics of the substrate specificity of the crude endogenous beta-lactamases of gram-negative bacteria].
PubMed:
Cryoprotective effects of some amides on rabbit spermatozoa.
PubMed:
[Beta-lactamase activity of bacteria of the genus Proteus].
PubMed:
[Studies on the pharmacodynamic activity of several drug solvents. 2. Glycerin, N-(beta-hydroxyethyl)-lactamide, polyethylene glycol 400].
PubMed:
Osmotic opening of the blood-brain barrier in the rhesus monkey without measurable brain edema.
PubMed:
Effect of hyperosmotic agents on the ciliary epithelium and trabecular meshwork.
PubMed:
Hydroxyethyl lactamide, a dye solvent useful in vital staining.
PubMed:
Pathological aspects of brain transport phenomena.
PubMed:
Catabolite repression of Pseudomonas aeruginosa amidase: the effect of carbon source on amidase synthesis.
PubMed:
Osmotic opening of the blood-brain barrier in the monkey without associated neurological deficits.
PubMed:
Apparent molal volume of glycine, glycolamide, alanine, lactamide, and glycylglycine in aqueous solution at 25 degrees and high pressures.