lactobionic acid

4-(b-D- dalactosido)-D-gluconic acid 4-O-b-D- galactopyranosyl-D-gluconic acid 4-O-beta-d- galactopyranosyl-dextro-gluconic acid D- gluconic acid, 4-O-b-D-galactopyranosyl- lactobionicacid (2R,3R,4R,5R)-2,3,5,6-tetrahydroxy-4-[(2S,3R,4S,5R,6R)-3,4,5- trihydroxy-6-(hydroxymethyl)oxan-2-yl]oxyhexanoic acid PubMed: Synthesis, biocompatible, and self-assembly properties of poly (ethylene glycol)/lactobionic acid-grafted chitosan. PubMed: Lactobionic acid coupled liposomes: an innovative strategy for targeting hepatocellular carcinoma. PubMed: Lactobionic Acid-modified dendrimer-entrapped gold nanoparticles for targeted computed tomography imaging of human hepatocellular carcinoma. PubMed: Targeting liver cancer via ASGP receptor using 5-FU-loaded surface-modified PLGA nanoparticles. PubMed: Glyco-nanoparticles with sheddable saccharide shells: a unique and potent platform for hepatoma-targeting delivery of anticancer drugs. PubMed: Polyvinylamine-G-galactose is a route to bioactivated silica surfaces. PubMed: The liver-targeting study of the N-galactosylated chitosan in vivo and in vitro. PubMed: Aqueous solubility of calcium L-lactate, calcium D-gluconate, and calcium D-lactobionate: importance of complex formation for solubility increase by hydroxycarboxylate mixtures. PubMed: Cellular behaviour of hepatocyte-like cells from nude mouse bone marrow-derived mesenchymal stem cells on galactosylated poly(D,L-lactic-co-glycolic acid). PubMed: Targeting Mantle Cell Lymphoma with Anti-SYK Nanoparticles. PubMed: Equilibrium surface tension, dynamic surface tension, and micellization properties of lactobionamide-type sugar-based gemini surfactants. PubMed: Bio-production of lactobionic acid: current status, applications and future prospects. PubMed: Hepatocyte-targeting gene transfer mediated by galactosylated poly(ethylene glycol)-graft-polyethylenimine derivative. PubMed: Feeding strategies for enhanced lactobionic acid production from whey by Pseudomonas taetrolens. PubMed: Selection method of pH conditions to establish Pseudomonas taetrolens physiological states and lactobionic acid production. PubMed: Cell-specific intracellular anticancer drug delivery from mesoporous silica nanoparticles with pH sensitivity. PubMed: Hydrotropic polymeric mixed micelles based on functional hyperbranched polyglycerol copolymers as hepatoma-targeting drug delivery system. PubMed: Production of organic acids by periplasmic enzymes present in free and immobilized cells of Zymomonas mobilis. PubMed: Hepatocyte-targeted delivery using ph-sensitive liposomes loaded with lactosylnorcantharidin phospholipid complex: preparation, characterization, and therapeutic evaluation in vivo and in vitro. PubMed: Physiological heterogeneity of Pseudomonas taetrolens during lactobionic acid production. PubMed: Lactobionic acid as antioxidant and moisturizing active in alkyl polyglucoside-based topical emulsions: the colloidal structure, stability and efficacy evaluation. PubMed: Galactosylated nanostructured lipid carriers for delivery of 5-FU to hepatocellular carcinoma. PubMed: Optimization of lactobionic acid production by Acetobacter orientalis isolated from Caucasian fermented milk, "Caspian Sea yogurt". PubMed: Role of dissolved oxygen availability on lactobionic acid production from whey by Pseudomonas taetrolens. PubMed: Application of lactobionic acid and nonionic surfactants as solubilizing agents for parenteral formulation of clarithromycin. PubMed: Does lactobionic acid affect the colloidal structure and skin moisturizing potential of the alkyl polyglucoside-based emulsion systems? PubMed: Production of lactobionic acid and sorbitol from lactose/fructose substrate using GFOR/GL enzymes from Zymomonas mobilis cells: a kinetic study. PubMed: Design and synthesis of dual-ligand modified chitosan as a liver targeting vector. PubMed: Metabolomic analysis of the toxic effects of chronic exposure to low-level dichlorvos on rats using ultra-performance liquid chromatography-mass spectrometry. PubMed: Efficient lactobionic acid production from whey by Pseudomonas taetrolens under pH-shift conditions. PubMed: Evaluation of clarithromycin lactobionate as a novel chiral selector for enantiomeric separation of basic drugs in capillary electrophoresis. PubMed: Development of a successive targeting liposome with multi-ligand for efficient targeting gene delivery. PubMed: Self-assembled virus-like particles from rotavirus structural protein VP6 for targeted drug delivery. PubMed: Analysis of experimental errors in bioprocesses. 1. Production of lactobionic acid and sorbitol using the GFOR (glucose-fructose oxidoreductase) enzyme from permeabilized cells of Zymomonas mobilis. PubMed: Mesoporous silica nanoparticles end-capped with collagen: redox-responsive nanoreservoirs for targeted drug delivery. PubMed: Fabrication of lactobionic-loaded chitosan microcapsules as potential drug carriers targeting the liver. PubMed: Galactosyl conjugated N-succinyl-chitosan-graft-polyethylenimine for targeting gene transfer. PubMed: Galectin inhibitory disaccharides promote tumour immunity in a breast cancer model. PubMed: Fluorine-18 labeled galactosylated chitosan for asialoglycoprotein-receptor-mediated hepatocyte imaging. PubMed: Development and in vitro characterization of galactosylated low molecular weight chitosan nanoparticles bearing doxorubicin. PubMed: Lactobionic acid in a natural alkylpolyglucoside-based vehicle: assessing safety and efficacy aspects in comparison to glycolic acid. PubMed: Galactosylated poly(2-(2-aminoethyoxy)ethoxy)phosphazene/DNA complex nanoparticles: in vitro and in vivo evaluation for gene delivery. PubMed: Galactosylated solid lipid nanoparticles with cucurbitacin B improves the liver targetability. PubMed: Porphyrin and galactosyl conjugated micelles for targeting photodynamic therapy. PubMed: Self-assembly and characterization of Pluronic P105 micelles for liver-targeted delivery of silybin. PubMed: Superparamagnetic iron oxide nanoparticles as a dual imaging probe for targeting hepatocytes in vivo. PubMed: Acute acidification of stratum corneum membrane domains using polyhydroxyl acids improves lipid processing and inhibits degradation of corneodesmosomes. PubMed: Galactosylated LDL nanoparticles: a novel targeting delivery system to deliver antigen to macrophages and enhance antigen specific T cell responses. PubMed: Effect of culture medium composition on Trichoderma reesei's morphology and cellulase production. PubMed: Amphiphilic perfluoroalkyl carbohydrates as new tools for liver imaging. PubMed: Immobilization of lactobionic acid on the surface of cadmium sulfide nanoparticles and their interaction with hepatocytes. PubMed: Maintenance of an acidic stratum corneum prevents emergence of murine atopic dermatitis. PubMed: Involvement of Acetobacter orientalis in the production of lactobionic acid in Caucasian yogurt ("Caspian Sea yogurt") in Japan. PubMed: Galactosylated fluorescent labeled micelles as a liver targeting drug carrier. PubMed: Kinetic modeling of a bi-enzymatic system for efficient conversion of lactose to lactobionic acid. PubMed: Green oxidation of renewable carbohydrates: lactobionic acid production as an example. PubMed: Lactose enhances cellulase production by the filamentous fungus Acremonium cellulolyticus. PubMed: Bubble-free oxygenation of a bi-enzymatic system: effect on biocatalyst stability. PubMed: Production of lactose-free galacto-oligosaccharide mixtures: comparison of two cellobiose dehydrogenases for the selective oxidation of lactose to lactobionic acid. PubMed: Purification and characterization of a carbohydrate: acceptor oxidoreductase from Paraconiothyrium sp. that produces lactobionic acid efficiently. PubMed: Inherent toxicity of organ preservation solutions to cultured hepatocytes. PubMed: Organic-inorganic mesoporous nanocarriers integrated with biogenic ligands. PubMed: Characterization of the bga1-encoded glycoside hydrolase family 35 beta-galactosidase of Hypocrea jecorina with galacto-beta-D-galactanase activity. PubMed: [Galactosylated derivatives of low-molecular-weight chitosan: production and properties]. PubMed: Synthesis of a novel glycoconjugated chitosan and preparation of its derived nanoparticles for targeting HepG2 cells. PubMed: Quantification of lactobionic acid and sorbitol from enzymatic reaction of fructose and lactose by high-performance liquid chromatography. PubMed: Identification of live liver cancer cells in a mixed cell system using galactose-conjugated fluorescent nanoparticles. PubMed: Oxidation of lactose to lactobionic acid by a Microdochium nivale carbohydrate oxidase: kinetics and operational stability. PubMed: Scale-up of enzymatic production of lactobionic acid using the rotary jet head system. PubMed: Enzymatically oxidized lactose and derivatives thereof as potential protein cross-linkers. PubMed: Surface modification of magnetite nanoparticles using lactobionic acid and their interaction with hepatocytes. PubMed: Dynamic seeding and perfusion culture of hepatocytes with galactosylated vegetable sponge in packed-bed bioreactor. PubMed: Tetranuclear copper(II) complexes bridged by alpha-D-glucose-1-phosphate and incorporation of sugar acids through the Cu4 core structural changes. PubMed: Asialoglycoprotein-receptor-targeted hepatocyte imaging using 99mTc galactosylated chitosan. PubMed: Uronic acids functionalized polyethyleneimine (PEI)-polyethyleneglycol (PEG)-graft-copolymers as novel synthetic gene carriers. PubMed: Sugar-based gemini surfactants with peptide bonds-synthesis, adsorption, micellization, and biodegradability. PubMed: Oxidation of lactose with bromine. PubMed: Synergistic effect of poly(ethylenimine) on the transfection efficiency of galactosylated chitosan/DNA complexes. PubMed: Morphology and metabolism of Ba-alginate encapsulated hepatocytes with galactosylated poly(allyl amine) and poly(vinyl alcohol) as extracellular matrices. PubMed: Hepatocyte-targeted nuclear imaging using 99mTc-galactosylated chitosan: conjugation, targeting, and biodistribution. PubMed: Polynorbornene polycationic polymers as gene transfer agents. Influence of the counterion for in vitro transfection. PubMed: Wide nanoscopic pore of maxi-anion channel suits its function as an ATP-conductive pathway. PubMed: Toxicological studies on Lactose Oxidase from Microdochium nivale expressed in Fusarium venenatum. PubMed: Lactose derivatives are inhibitors of Trypanosoma cruzi trans-sialidase activity toward conventional substrates in vitro and in vivo. PubMed: Co-culture of hepatocytes and fibroblasts by micropatterned immobilization of beta-galactose derivatives. PubMed: Galactosylated chitosan/DNA nanoparticles prepared using water-soluble chitosan as a gene carrier. PubMed: The use of polyhydroxy acids (PHAs) in photoaged skin. PubMed: Kinetics and mechanism of the reduction of CrVI and CrV by D-lactobionic acid. PubMed: Evaluation of a galactose-carrying gelatin sponge for hepatocytes culture and transplantation. PubMed: Morphology and metabolism of Ba-alginate-encapsulated hepatocytes with galactosylated chitosan and poly(vinyl alcohol) as extracellular matrices. PubMed: Oxygen solubilities of media used in electrochemical respiration measurements. PubMed: Development of polymeric nanoparticulate drug delivery systems: evaluation of nanoparticles based on biotinylated poly(ethylene glycol) with sugar moiety. PubMed: Galactosylated low molecular weight chitosan as DNA carrier for hepatocyte-targeting. PubMed: Development of a polymeric nanoparticulate drug delivery system. In vitro characterization of nanoparticles based on sugar-containing conjugates. PubMed: Preparation of alginate/galactosylated chitosan scaffold for hepatocyte attachment. PubMed: Anionic polysaccharides. A class of substances with hepatoprotective and antiadhesive properties in rat liver preservation. PubMed: Galactosylated chitosan-graft-poly(ethylene glycol) as hepatocyte-targeting DNA carrier. PubMed: Synthesis and Surface Properties of N-Alkyl-N-methylgluconamides and N-Alkyl-N-methyllactobionamides. PubMed: Hexose oxidase from Chondrus crispus: improved purification using perfusion chromatography(*). PubMed: [Preparation, X-ray structural and spectroscopic studies of some D-lactobionic acid complexes with Cs(I), Fe(III) and di-n-butyltin(IV)]. PubMed: Performances of new sugar-bearing poly(acrylamide) copolymers as DNA sieving matrices and capillary coatings for electrophoresis. PubMed: Protective effects of lactobionate in modified phosphate-buffered sucrose. PubMed: Evaluation of several saccharides as osmotic agent for peritoneal dialysate. PubMed: Self-assembled hydrogel nanoparticles from curdlan derivatives: characterization, anti-cancer drug release and interaction with a hepatoma cell line (HepG2). PubMed: Inhibitory effect of erythromycin on P-glycoprotein-mediated biliary excretion of doxorubicin in rats. PubMed: Galactosylated chitosan-graft-dextran as hepatocyte-targeting DNA carrier. PubMed: The stimulation of antral motility by erythromycin is attenuated by hyperglycemia. PubMed: Glutathione, lactobionate, and histidine: cryptic inhibitors of matrix metalloproteinases contained in University of Wisconsin and histidine/tryptophan/ketoglutarate liver preservation solutions. PubMed: Spontaneous Vesicle Formation by Helical Glycopeptides in Water. PubMed: Amino acid residues of heparin cofactor II required for stimulation of thrombin inhibition by sulphated polyanions. PubMed: The effect of lactose derivatives on intestinal lactic acid bacteria. PubMed: Doxorubicin physical state in solution and inside liposomes loaded via a pH gradient. PubMed: Effect of inline filtration on ViaSpan cold-storage solution. PubMed: In vitro effects of aprosulate sodium, a novel anticoagulant, on platelet activation: possible mechanism for antiplatelet action. PubMed: Determination of raffinose and lactobionic acid in ViaSpan by anion exchange chromatography with pulsed amperometric detection. PubMed: Synthesis of glycolipids containing disaccharides and two longer alkyl chains and their applications as enzyme modifiers. PubMed: Effects of different cold preservation solutions on restoration of hepatic energy metabolism during cold reperfusion. PubMed: Effects of cation interactions on sugar anion conformation in complexes of lactobionate and gluconate with calcium, sodium or potassium. PubMed: Interaction between the sulfated lactobionic acid (LW 10082) and other antithrombotic agents in animal thrombosis model. PubMed: Analysis of heparin-like pharmaceuticals by capillary zone electrophoresis and isotachophoresis. PubMed: Cardioplegic protection of hearts with pre-arrest ischaemic injury: effect of glucose, aspartate, and lactobionate. PubMed: Synthesis of model glycolipids having two long alkyl chains. PubMed: Effects of calcium concentration, lactobionate content, and sodium/ potassium ratio of preservation solutions on resting left ventricular pressure and postreperfusion function of rabbit heterotopic heart transplants. PubMed: Inhibition of hydroxyl radical production by lactobionate, adenine, and tempol. PubMed: Sulfated polysaccharide anticoagulants suppress natural killer cell activity in vitro. PubMed: In vivo comparative study of two lactobionate based solutions for prolonged heart preservation. PubMed: Restoration of hepatic metabolism by cold reperfusion. PubMed: Organ preservation. PubMed: An underlying mechanism for improved liver preservation with a combined histidine-lactobionate-raffinose flush solution. PubMed: High-performance capillary electrophoresis of O-glycosidically linked sialic acid-containing oligosaccharides in glycoproteins as their alditol derivatives with low-wavelength UV monitoring. PubMed: Current trends in the development of anticoagulant and antithrombotic drugs. PubMed: Reduced production of the deleterious hydroxyl free radical during the final reperfusion of isolated rabbit heart with the use of an improved sodium lactobionate-based cardioplegic medium. PubMed: Rapid assessment of islet cell viability by MTT assay after cold storage in different solutions. PubMed: Improvements in human islet purification by inclusion of a colloid in cold storage solutions. PubMed: Rinse solution containing a protease inhibitor and Na-lactobionate increases graft survival after rat pancreas preservation. PubMed: Protamine sulfate neutralization of the anticoagulant activity of Aprosulate, a synthetic sulfated lactobionic acid amide. PubMed: The in vitro influence of sulfated bis-lactobionic acid amides on O6-alkylguanine-DNA alkyltransferase, DNase I, nucleic acid synthesis and chromatin structure. PubMed: A prospective randomized clinical trial of liver preservation using high-sodium versus high-potassium lactobionate/raffinose solution. PubMed: [Addition of an osmotic agent to liver preservative solutions in a model of in vitro preservation of hepatocytes]. PubMed: Heart-lung protection from ischemic injury during 8 hour hypothermic preservation. PubMed: Carbon tetrachloride-induced cell death in perfused livers from phenobarbital-pretreated rats under hypoxic conditions and various ionic milieu. Further evidence for calcium-dependent irreversible changes. PubMed: 31P NMR studies of rat liver cold preservation with histidine-buffered lactobionate solution. PubMed: Efficacy of lactobionate-enriched cardioplegic solution in preserving compliance of cold-stored heart transplants. PubMed: A lactobionate-based extracellular-type solution for donor heart preservation. PubMed: Molecular weight profiling of low molecular weight heparins utilizing a heparinase degraded oligosaccharide mixture as a calibrator. PubMed: Production of novel oligosaccharide oxidase by wheat bran solid-state fermentation. PubMed: Lactobionic and gluconic acid complexes of FeII and FeIII; control of oxidation pathways by an organ transplantation preservant. PubMed: Antithrombin III- and heparin cofactor II-mediated anticoagulant and antiprotease actions of heparin and its synthetic analogues. PubMed: An examination of the effects of solutions containing histidine and lactobionate for heart, pancreas, and liver preservation in the rat. PubMed: Determination of the association constant of monovalent mode protein-sugar interaction by capillary zone electrophoresis. PubMed: A comparison of some simplified lactobionate preservation solutions with standard UW solution and Eurocollins solution for pancreas preservation. PubMed: Calcium antagonists in sodium lactobionate sucrose solution for rat liver preservation. PubMed: Inhibition of factor X, factor V and prothrombin activation by the bis(lactobionic acid amide) LW10082. PubMed: A comparison of histadine lactobionate solution with University of Wisconsin solution for rat liver and heart preservation. PubMed: Prolonged rat pancreas preservation using a solution with the combination of histidine and lactobionate. PubMed: Influence of hypersulfated lactobionic acid amides on tissue plasminogen activator release. PubMed: The need for glutathione and allopurinol in HL solution for rat liver preservation. PubMed: Successful 20-hour rat liver preservation with chlorpromazine in sodium lactobionate sucrose solution. PubMed: Interaction of the sulfated lactobionic acid amide LW 10082 with thrombin and its endogenous inhibitors. PubMed: Influence of synthetic sulfated bis-lactobionic acid amides on tissue-type plasminogen activator release. PubMed: A comparison of a new solution combining histidine and lactobionate with UW solution and eurocollins for rat liver preservation. PubMed: Pharmacologic profile of the antithrombotic and bleeding actions of sulfated lactobionic acid amides. PubMed: Influence of lactobionic acid on the kinetics of thrombin in human plasma. PubMed: Protamine sulfate neutralization of lactobionic acid amides. PubMed: Pharmacodynamics of a sulfated lactobionic acid amide-derived antithrombotic agent (Aprosulate) in primates. PubMed: Modulation of the enzymatic activity of alpha-thrombin by polyanions: consequences on intrinsic activation of factor V and factor VIII. PubMed: [Effect of subcutaneous administration of lactobionic acid on coagulation and platelet function]. PubMed: Biochemical studies on sulfated lactobionic acid amides. PubMed: University of Wisconsin solution without lactobionate and raffinose. Protection of metabolism in cold-stored kidneys. PubMed: Lactobionate as the most important component in UW solution for liver preservation. PubMed: Examination of the role of the impermeants lactobionate and raffinose in a modified UW solution. PubMed: The effect of bismuth on the selective oxidation of lactose on supported palladium catalysts. PubMed: Purification and properties of two lactose hydrolases from Trichosporon cutaneum. PubMed: Analysis of UW solution in a rat liver transplant model. PubMed: Important components of the UW solution. PubMed: Anticoagulant and antithrombotic properties of synthetic sulfated bis-lactobionic acid amides. PubMed: Hypothermic perfusion of rabbit livers: effect of perfusate composition (Ca and lactobionate) on enzyme release and tissue swelling. PubMed: The response of liver to lactobionate/raffinose (University of Wisconsin--UW) solution during hypothermic preservation: a study using 31phosphorus nuclear magnetic resonance. PubMed: Lactobionic acid as an iron chelator: a rationale for its effectiveness as an organ preservant. PubMed: Successful 72-hour cold storage of dog kidneys with UW solution. PubMed: Partial purification and characterization of Naegleria fowleri beta-glucosidase. PubMed: Studies on monovalent anaphylactogens with carbohydrate auxiliary groups: exclusion of an artefact. PubMed: Lactose inhibits the growth of Rhizobium meliloti cells that contain an actively expressed Escherichia coli lactose operon. PubMed: Regulation of lactose-phosphoenolpyruvate-dependent phosphotransferase system and beta-D-phosphogalactoside galactohydrolase activities in Lactobacillus casei. PubMed: Bioavailability of iron- and copper-supplemented milk for Mexican school children. PubMed: Inhibition of ischemic induced cellular swelling in kidney cortex tissue by lactobionate anions. PubMed: Distinct galactose phosphoenolpyruvate-dependent phosphotransferase system in Streptococcus lactis. PubMed: Changes in the substrate specificities of an enzyme during directed evolution of new functions. PubMed: Physiological studies of beta-galactosidase induction in Kluyveromyces lactis. PubMed: The metabolism of carbohydrates by extremely halophilic bacteria: the identification of lactobionic acid as a product of lactose metabolism by Halobacterium saccharovorum. PubMed: Enzymic formation of lactobionic acid from lactose. PubMed: Evidence for the formation and utilization of lactobionic acid by Penicillium chrysogenum. PubMed: [Oxidation of lactose in lactobionic acid by pathogenic or saprophytic bacteria (Bacterium anitratum)].