lithium carbonate

carbonic acid, lithium salt (1:2)

CAS: 554-13-2 C Li2 O3 MW: 73.89060000

Identification

Namelithium carbonate
CAS Number554-13-2
EINECS209-062-5
FDA UNII2BMD2GNA4V
Molecular FormulaC Li2 O3
Molecular Weight73.89060000
MDL NumberMFCD00011084
Nikkaji NumberJ425A
Beilstein3999191

Regulatory

Physical Properties

Appearance white powder (est)
Assay 95.00 to 100.00
Food Chemicals Codex Listed No
Specific Gravity 2.11000 @ 25.00 °C.
Melting Point 723.00 °C. @ 760.00 mm Hg (est)
Boiling Point 333.60 °C. @ 760.00 mm Hg (est)
Vapor Pressure 0.000026 mmHg @ 25.00 °C. (est)
Flash Point 338.00 °F. TCC ( 169.80 °C. ) (est)
logP (o/w) -0.809 (est)
Soluble in water, 1e+006 mg/L @ 25 °C (est)

Cosmetic Information

CosIngcosmetic data
Cosmetic Usesbuffering agents

No sensory data available

Safety Information

Preferred SDSView
Oral/Parenteral Toxicityoral-dog LD50 500 mg/kg
Dermal Toxicitysubcutaneous-mouse LD50 413 mg/kg
Inhalation ToxicityNot determined

GHS Classification

['GHS Classification in accordance with 29 CFR 1910 (OSHA HCS)', 'GHS Label elements, including precautionary statements', 'BEHAVIORAL: ATAXIA\nBEHAVIORAL: ALTERED SLEEP TIME (INCLUDING CHANGE IN RIGHTING REFLEX)\nBEHAVIORAL: EXCITEMENT', 'LUNGS, THORAX, OR RESPIRATION: RESPIRATORY DEPRESSION\nBEHAVIORAL: ALTERED SLEEP TIME (INCLUDING CHANGE IN RIGHTING REFLEX)', 'BEHAVIORAL: ALTERED SLEEP TIME (INCLUDING CHANGE IN RIGHTING REFLEX)\nLUNGS, THORAX, OR RESPIRATION: RESPIRATORY DEPRESSION']

Safety in Use

Categorycosmetic agents
Recommendation for lithium carbonate usage levels up tonot for fragrance use.
Recommendation for lithium carbonate flavor usage levels up tonot for flavor use.

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Potential Uses

None Found

Natural Occurrence

not found in nature

Synonyms

camcolit carbonic acid dilithium salt carbonic acid lithium salt carbonic acid lithium salt (Li2CO3) carbonic acid, dilithium salt carbonic acid, lithium salt (1:2) ceglution dilithium carbonate dilithium trioxidocarbonate dilithium;carbonate dilithium(1+) ion carbonate eskalith hypnorex lithicarb lithionate lithium carbonate (Li2CO3) lithium phasal lithiumcarbonate lithizine lithobid lithocarb lithonate lithotabs maniprex plenur PubMed: Improving lithium therapeutics by crystal engineering of novel ionic cocrystals. PubMed: Synergistic interaction between caloric restriction and amphetamine in food-unrelated approach behavior of rats. PubMed: [Ramadan and bipolar disorder: Example of circadian rhythm disturbance and its impact on patients with bipolar disorders]. PubMed: Enrichment of mushrooms: an interesting strategy for the acquisition of lithium. PubMed: Lipid peroxidation, antioxidant activities and stress protein (HSP72/73, GRP94) expression in kidney and liver of rats under lithium treatment. PubMed: Neuroprotective and neurotrophic effects of long term lithium treatment in mouse brain. PubMed: Gelatinous marrow transformation and hematopoietic atrophy in a miniature horse stallion. PubMed: Commercial and non-commercial 'championing' of medications. PubMed: Chronic lithium administration triggers an over-expression of GRP94 stress protein isoforms in mouse liver. PubMed: Update on neuropsychiatric symptoms of dementia: evaluation and management. PubMed: Aripiprazole therapy in 20 older adults with bipolar disorder: a 12-week, open-label trial. PubMed: Amiloride restores renal medullary osmolytes in lithium-induced nephrogenic diabetes insipidus. PubMed: Clinical decision making in the treatment of mania. PubMed: Monotherapy versus combined treatment with second-generation antipsychotics in bipolar disorder. PubMed: An analysis of the efficacy of treatments for bipolar depression. PubMed: Changes in growth rate and thyroid- and sex-hormones blood levels in rats under sub-chronic lithium treatment. PubMed: [Side effects of low serum lithium concentrations on renal, thyroid, and sexual functions in male and female rats]. PubMed: Lithium intoxication, hypercalcemia and "accidentally" induced food and water aversion: a case report. PubMed: Lithium interaction with the cyclooxygenase 2 inhibitors rofecoxib and celecoxib and other nonsteroidal anti-inflammatory drugs. PubMed: Production of radioactive particles for use in environmental studies. PubMed: Thermal dehydration-induced thirst in lithium-treated rats. PubMed: A practical and convenient synthesis of hotrienol, an excellent fruity smelling compound. PubMed: Effect of three different diets on the bioavailability of a sustained release lithium carbonate matrix tablet. PubMed: Lithium's effects on rat liver glucose metabolism in vivo. PubMed: Early North American research on lithium. PubMed: Evaluation of the in vitro and in vivo performance of two sustained-release lithium carbonate matrix tablets. Effect of different diets on the bioavailability. PubMed: Determination of discretionary salt intake in rural Guatemala and Benin to determine the iodine fortification of salt required to control iodine deficiency disorders: studies using lithium-labeled salt. PubMed: Effect of lithium on hepatic lipid peroxidation and antioxidative enzymes under different dietary protein regimens. PubMed: Lithium plus valproate as maintenance polypharmacy for patients with bipolar I disorder: a review. PubMed: Lithium and neuroleptics in combination: is there enhancement of neurotoxicity leading to permanent sequelae? PubMed: Effect of lithium carbonate on activity level and circadian period in different strains of rats. PubMed: Combined action of lead and lithium on essential and nonessential elements in rat blood. PubMed: Leukocytoclastic vasculitis caused by drug additives. PubMed: Single daily dosage of lithium carbonate. PubMed: Liberation of lithium from sustained release preparations. A comparison of seven registered brands. PubMed: Daidzin and daidzein suppress free-choice ethanol intake by Syrian golden hamsters. PubMed: Influence of high fat diet on steady state bioavailability of lithium carbonate in manic depressive patients - a preliminary report. PubMed: Advances in therapy for hairy cell leukemia. A review. PubMed: Lithium intoxication: a coordinated treatment approach. PubMed: The pharmacologic treatment of conduct disorders and rage outbursts. PubMed: Relative contributions of dietary sodium sources. PubMed: The immune system is a key factor in the etiology of psychosocial disease. PubMed: Lithium lengthens circadian period in a diurnal primate, Saimiri sciureus. PubMed: Effect of lithium carbonate on mouse and rat embryos in vitro. PubMed: The role of pharmacotherapy in anorexia nervosa and bulimia. PubMed: Evaluation and management of premenstrual syndrome in clinical psychiatric practice. PubMed: An assessment of the sources of dietary salt in a British population. PubMed: The potential use of lithium as a marker for the assessment of the sources of dietary salt: cooking studies and physiological experiments in men. PubMed: Manic-depressive illness in children: treatment with lithium carbonate. PubMed: Comparing oral lithium carbonate and intraperitoneal lithium chloride chronic administrations on rats' activity levels. PubMed: The effect of lithium carbonate administration on growth in the domestic fowl. PubMed: Effects of acute oral administration of lithium compounds on multiple schedule performance in rats. PubMed: A novel technique for assessing the sources of dietary sodium. PubMed: Effects of lithium on [3H](-)quinuclidinyl benzilate [( 3H](-)QNB) binding to rat brain muscarinic cholinergic receptors. PubMed: Haloperidol: a quarter century of experience. PubMed: [Effect of lithium on fat, protein and water content in rats]. PubMed: Lithium carbonate and the drug lag. PubMed: [Influence of lithium on the in vitro deiodination of L-thyroxine in the rat liver]. PubMed: Locomotor activity and plasma, red blood cell and cerebral cortex lithium concentration in inbred mice given lithium carbonate. PubMed: Lithium orotate, carbonate and chloride: pharmacokinetics, polyuria in rats. PubMed: Blood levels and management of lithium treatment. PubMed: Lithium carbonate. PubMed: Lithium carbonate: some recommendations.