magnesium pyrophosphate
diphosphoric acid magnesium salt (1:2)
Identification
| Name | magnesium pyrophosphate |
| CAS Number | 13446-24-7 |
| EINECS | 236-595-0 |
| FDA UNII | AL34Y660JV |
| Molecular Formula | Mg2 O7 P2 |
| Molecular Weight | 222.55192400 |
| MDL Number | MFCD00049482 |
Regulatory
| DG SANTE Food Additives | magnesium dihydrogen diphosphate |
Physical Properties
| Food Chemicals Codex Listed | No |
| Specific Gravity | 2.56000 @ 25.00 °C. |
| Flash Point | 32.00 °F. TCC ( 0.00 °C. ) (est) |
No sensory data available
Safety Information
| Preferred SDS | View |
| Oral/Parenteral Toxicity | Not determined |
| Dermal Toxicity | Not determined |
| Inhalation Toxicity | Not determined |
GHS Classification
['GHS Classification in accordance with 29 CFR 1910 (OSHA HCS)', 'GHS Label elements, including precautionary statements']
Safety in Use
| Category | leavening agents, acidity regulators |
| Recommendation for magnesium pyrophosphate usage levels up to | not for fragrance use. |
| Recommendation for magnesium pyrophosphate flavor usage levels up to | not for flavor use. |
No supplier data available
Potential Uses
Natural Occurrence
Synonyms
dimagnesium phosphonato phosphate
diphosphoric acid magnesium salt (1:2)
magnesium dihydrogen diphosphate
PubMed:
Demonstration of a very inexpensive, turbidimetric, real-time, RT-LAMP detection platform using shrimp Laem-Singh virus (LSNV) as a model.
PubMed:
Layer-by-Layer Assembled Antisense DNA Microsponge Particles for Efficient Delivery of Cancer Therapeutics.
PubMed:
A microfluidic system integrated with buried optical fibers for detection of Phalaenopsis orchid pathogens.
PubMed:
Monitoring the progression of loop-mediated isothermal amplification using conductivity.
PubMed:
RNAi-microsponges form through self-assembly of the organic and inorganic products of transcription.
PubMed:
Low-tech detection methods for amplification products.
PubMed:
Determination of phosphate phases in sewage sludge ash-based fertilizers by Raman microspectroscopy.
PubMed:
Determination of phosphorus fertilizer soil reactions by Raman and synchrotron infrared microspectroscopy.
PubMed:
Embryo sexing and sex chromosomal chimerism analysis by loop-mediated isothermal amplification in cattle and water buffaloes.
PubMed:
Oxidation desensitizes actomyosin to magnesium pyrophosphate-induced dissociation.
PubMed:
Struvite pyrolysate recycling combined with dry pyrolysis for ammonium removal from wastewater.
PubMed:
Temperature-dependent phosphorus precipitation and chromium removal from struvite-saturated solutions.
PubMed:
Combination of struvite pyrolysate recycling with mixed-base technology for removing ammonium from fertilizer wastewater.
PubMed:
Development of a loop-mediated isothermal amplification assay for detection of Phytophthora sojae.
PubMed:
A multiphysics model of in vitro transcription coupling enzymatic reaction and precipitation formation.
PubMed:
Evaluation of certain food additives.
PubMed:
Rapid detection of the most common high-risk human papillomaviruses by loop-mediated isothermal amplification.
PubMed:
Detection of shrimp Taura syndrome virus by loop-mediated isothermal amplification using a designed portable multi-channel turbidimeter.
PubMed:
Chemical composition and microstructure of uroliths associated with the feeding of high-level cottonseed meal diet to sheep.
PubMed:
Insights into the importance of hydrogen bonding in the gamma-phosphate binding pocket of myosin: structural and functional studies of serine 236.
PubMed:
Optimisation of reverse transcriptase loop-mediated isothermal amplification assay for rapid detection of Macrobrachium rosenbergii noda virus and extra small virus in Macrobrachium rosenbergii.
PubMed:
Evaluation of trends in urolith composition and characteristics of dogs with urolithiasis: 25,499 cases (1985-2006).
PubMed:
Real-time reverse transcription loop-mediated isothermal amplification for rapid detection of yellow head virus in shrimp.
PubMed:
Rapid, sensitive and simple detection method for koi herpesvirus using loop-mediated isothermal amplification.
PubMed:
Rapid and sensitive detection of Lophophora williamsii by loop-mediated isothermal amplification.
PubMed:
Enhanced uridine diphosphate N-acetylglucosamine production using whole-cell catalysis.
PubMed:
Sensitive and rapid detection of peach latent mosaic viroid by the reverse transcription loop-mediated isothermal amplification.
PubMed:
State-dependent modulation of CFTR gating by pyrophosphate.
PubMed:
Colorimetric detection of loop-mediated isothermal amplification reaction by using hydroxy naphthol blue.
PubMed:
Detection of Ralstonia solanacearum by loop-mediated isothermal amplification.
PubMed:
Examination of intrinsic sulfonamide resistance in Bacillus anthracis: a novel assay for dihydropteroate synthase.
PubMed:
Rapid identification of Curcuma longa and C. aromatica by LAMP.
PubMed:
Evaluation of trends in urolith composition in cats: 5,230 cases (1985-2004).
PubMed:
Rapid detection of Actinobacillus actinomycetemcomitans using a loop-mediated isothermal amplification method.
PubMed:
ATP as effector of inorganic pyrophosphatase of Escherichia coli. Identification of the binding site for ATP.
PubMed:
Binding of substrate at the effector site of pyrophosphatase increases the rate of its hydrolysis at the active site.
PubMed:
X-ray crystal structure of aristolochene synthase from Aspergillus terreus and evolution of templates for the cyclization of farnesyl diphosphate.
PubMed:
Rapid and sensitive detection of heat-labile I and heat-stable I enterotoxin genes of enterotoxigenic Escherichia coli by Loop-Mediated Isothermal Amplification.
PubMed:
Rapid detection of Macrobrachium rosenbergii nodavirus (MrNV) and extra small virus (XSV), the pathogenic agents of white tail disease of Macrobrachium rosenbergii (De Man), by loop-mediated isothermal amplification.
PubMed:
Detection of canine parvovirus in fecal samples using loop-mediated isothermal amplification.
PubMed:
The determination of phosphorus containing compounds in dental casting investment products by 31P solid-state MAS-NMR spectroscopy.
PubMed:
Sensitive and rapid detection of infectious hypodermal and hematopoietic necrosis virus (IHHNV) in shrimps by loop-mediated isothermal amplification.
PubMed:
Removal of aqueous ammonium with magnesium phosphates obtained from the ammonium-elimination of magnesium ammonium phosphate.
PubMed:
[A cationic cluster of amino acid residues of inorganic pyrophosphatase from Escherichia coli as a possible site of effector binding].
PubMed:
Kinetic studies of yeast polyA polymerase indicate an induced fit mechanism for nucleotide specificity.
PubMed:
Metal-free PPi activates hydrolysis of MgPPi by an Escherichia coli inorganic pyrophosphatase.
PubMed:
Detection of periodontal pathogen Porphyromonas gingivalis by loop-mediated isothermal amplification method.
PubMed:
[Principle of LAMP method--a simple and rapid gene amplification method].
PubMed:
Rapid detection of a fish iridovirus using loop-mediated isothermal amplification (LAMP).
PubMed:
Real-time turbidimetry of LAMP reaction for quantifying template DNA.
PubMed:
Detection of Japanese yam mosaic virus by RT-LAMP.
PubMed:
Use of loop-mediated isothermal amplification of the IS900 sequence for rapid detection of cultured Mycobacterium avium subsp. paratuberculosis.
PubMed:
Detection of tomato yellow leaf curl virus by loop-mediated isothermal amplification reaction.
PubMed:
Detection of loop-mediated isothermal amplification reaction by turbidity derived from magnesium pyrophosphate formation.
PubMed:
Structural characterization of the enzyme-substrate, enzyme-intermediate, and enzyme-product complexes of thiamin phosphate synthase.
PubMed:
A transition-state analogue reduces protein dynamics in hypoxanthine-guanine phosphoribosyltransferase.
PubMed:
Crystal structures of Giardia lamblia guanine phosphoribosyltransferase at 1.75 A(,).
PubMed:
Mechanism of Ca2+-induced inhibition of Escherichia coli inorganic pyrophosphatase.
PubMed:
The 2.0 A structure of human hypoxanthine-guanine phosphoribosyltransferase in complex with a transition-state analog inhibitor.
PubMed:
Transition-state analogs as inhibitors of human and malarial hypoxanthine-guanine phosphoribosyltransferases.
PubMed:
Motional dynamics of the catalytic loop in OMP synthase.
PubMed:
Bacillus subtilis ORF yybQ encodes a manganese-dependent inorganic pyrophosphatase with distinctive properties: the first of a new class of soluble pyrophosphatase?
PubMed:
Purification, properties, and multiple forms of a manganese-activated inorganic pyrophosphatase from Bacillus subtilis.
PubMed:
The Role of Magnesium, Pyrophosphate, and Their Complexes as Substrates and Activators of the Vacuolar H+-Pumping Inorganic Pyrophosphatase (Studies Using Ligand Protection from Covalent Inhibitors).
PubMed:
Catalysis by Escherichia coli inorganic pyrophosphatase: pH and Mg2+ dependence.
PubMed:
The importance of conserved residues in human liver UDPglucose pyrophosphorylase.
PubMed:
Cross-bridge binding to actin and force generation in skinned fibers of the rabbit psoas muscle in the presence of antibody fragments against the N-terminus of actin.
PubMed:
X-ray structure of the magnesium(II)-pyrophosphate complex of the truncated head of Dictyostelium discoideum myosin to 2.7 A resolution.
PubMed:
Location and properties of pyrophosphate-binding sites in Escherichia coli F1-ATPase.
PubMed:
Interactions of calcium and magnesium with the mitochondrial inorganic pyrophosphatase from Saccharomyces cerevisiae.
PubMed:
Localization of two myosin-subfragment-1 binding contacts in the 96-132 region of actin subdomain-1.
PubMed:
State-dependent radial elasticity of attached cross-bridges in single skinned fibres of rabbit psoas muscle.
PubMed:
Inorganic pyrophosphatase from bovine retinal rod outer segments.
PubMed:
Kinetics of the Vacuolar H-Pyrophosphatase : The Roles of Magnesium, Pyrophosphate, and their Complexes as Substrates, Activators, and Inhibitors.
PubMed:
Crystal chemistry of Mg2P2O7.nH2O, n = 0, 2 and 6: magnesium-oxygen coordination and pyrophosphate ligation and conformation.
PubMed:
Effects of magnesium pyrophosphate on mechanical properties of skinned smooth muscle from the guinea pig taenia coli.
PubMed:
Two pathways of pyrophosphate hydrolysis and synthesis by yeast inorganic pyrophosphatase.
PubMed:
Steady-state kinetics of the schistosomal hypoxanthine-guanine phosphoribosyltransferase.
PubMed:
The molecular origin of birefringence in skeletal muscle. Contribution of myosin subfragment S-1.
PubMed:
Effect of ionic strength on skinned rabbit psoas fibers in the presence of magnesium pyrophosphate.
PubMed:
Effect of nucleotides, actin and temperature on thermolysin digestion of myosin subfragment-1.
PubMed:
Properties of a polycation-stimulated protein kinase associated with purified Avena phytochrome.
PubMed:
Comparative studies on the electrical properties of the H+ translocating ATPase and pyrophosphatase of the vacuolar-lysosomal compartment.
PubMed:
[Introduction of an enzyme method for determining pyrophosphate in urine--a comparative study between patients with calculi and normal probands].
PubMed:
[The effect of pyrophosphate on the rigor fibers of rabbit m. psoas fibers].
PubMed:
The effect of pyrophosphate on the reaction of myosin with 2,4,6-trinitrobenzene sulphonate.
PubMed:
Energetics of the actomyosin bond in the filament array of muscle fibers.
PubMed:
Manganese complexes and the generation and scavenging of hydroxyl free radicals.
PubMed:
The medical and metabolic consequences of administration of sodium acetate.
PubMed:
The effects of pyrophosphate on myosin heads and on fiber stiffness.
PubMed:
Possible cooperativity in crossbridge detachment in muscle fibers having magnesium pyrophosphate at the active site.
PubMed:
Effect of glycosaminoglycans on calcium pyrophosphate crystal formation in collagen gels.
PubMed:
Proximity and ligand-induced movement of interdomain residues in myosin subfragment 1 containing trapped MgADP and MgPPi probed by multifunctional cross-linking.
PubMed:
Ca2+-sensitive cross-bridge dissociation in the presence of magnesium pyrophosphate in skinned rabbit psoas fibers.
PubMed:
The myosin filament. XII. Effect of MgATP on assembly.
PubMed:
Stiffness of skinned rabbit psoas fibers in MgATP and MgPPi solution.
PubMed:
Actin-attached and detached crossbridges in myofibrils: segregation into two populations according to their sensitivity to proteolytic digestion of myosin heavy chain.
PubMed:
Resolution of the competitive inhibitory effects of lithium and AMPPNP on the beat frequency of ATP-reactivated, demembranated, sea urchin sperm flagella.
PubMed:
The quaternary structure of E. coli inorganic pyrophosphatase is not required for catalytic activity.
PubMed:
Tryptic digestion of rabbit skeletal myofibrils: an enzymatic probe of myosin cross-bridges.
PubMed:
Investigation of the role of the substrate metal ion in the yeast inorganic pyrophosphatase reaction.
PubMed:
Stepwise changes in crossbridge state and sarcomere length: do lattice constraints play a critical role?
PubMed:
Kinetic anticooperativity in pre-steady-state formation of tryptophanyl adenylate by tryptophanyl-tRNA synthetase from beef pancreas. A consequence of the tryptophan anticooperative binding.
PubMed:
The stereochemical course of nucleotidyl transfer catalyzed by ATP sulfurylase.
PubMed:
[Some features of methylpyrophosphate hydrolysis by yeast inorganic pyrophosphatase].
PubMed:
Calcium and ATP regulation of the oscillatory torsional movement in a triton model of Physarum plasmodial strands.
PubMed:
Inorganic pyrophosphatase activity in oral streptococci: purification and properties of the enzyme from Streptococcus salivarius.
PubMed:
The effect of calcium and magnesium ions on calcium pyrophosphate crystal formation in aqueous solutions.
PubMed:
Reactive lysyl of myosin subfragment 1: location on the 27K fragment and labeling properties.
PubMed:
Calcium pyrophosphate crystal formation in aqueous solutions.
PubMed:
Internal motions in myosin.
PubMed:
Kinetic studies of the interaction of uranyl ions with inorganic pyrophosphatase from baker's yeast.
PubMed:
Immobilized ATP and actin columns as a tool for the characterization and separation of different myosins and active myosin fragments.
PubMed:
Purification and characterization of myosin from the clonal rat glial cell strain C-6.
PubMed:
Determination of phosphorus in phosphazenes and phosphines.
PubMed:
Inhibitor of spinach chloroplast fructose-1,6-diphosphatase by MgATP--,MgADP-and magnesium pyrophosphate (MgP207--).
PubMed:
Interactions between magnesium, pyrophosphate, and the contractile elements.
PubMed:
The relation between the magnesium-pyrophosphate complex and the actomyosin reaction to adenosinetriphosphate.