Identification

Namemethyl methacrylate
IUPACmethyl 2-methylprop-2-enoate
CAS Number80-62-6
EINECS201-297-1
FDA UNII196OC77688
Molecular FormulaC5 H8 O2
Molecular Weight100.11716000
MDL NumberMFCD00008587
Nikkaji NumberJ3.532G
Beilstein0605459
XlogP31.40 (est)

Regulatory

JECFA Food Flavoring1834 methyl 2-methyl-2-propenoate
DG SANTE Food Flavourings09.647 methyl methacrylate
DG SANTE Food Contact Materialsmethyl methacrylate
FEMA Number4002
FDANo longer provide for the use of these seven synthetic flavoring substances
FDA Mainterm (SATF)80-62-6 ; METHYL METHACRYLATE
FDA Mainterm (IAUFC)80-62-6 ; METHYL METHACRYLATE
FDA RegulationFDA PART 175 -- INDIRECT FOOD ADDITIVES: ADHESIVES AND COMPONENTS OF COATINGS

Physical Properties

Appearance colorless clear liquid (est)
Assay 95.00 to 100.00
Food Chemicals Codex Listed No
Specific Gravity 0.93300 to 0.93900 @ 25.00 °C.
Pounds per Gallon - (est). 7.763 to 7.813
Refractive Index 1.40900 to 1.41500 @ 20.00 °C.
Melting Point -49.00 to -47.00 °C. @ 760.00 mm Hg
Boiling Point 98.00 to 100.00 °C. @ 760.00 mm Hg
Vapor Pressure 36.889999 mmHg @ 25.00 °C. (est)
Vapor Density 3.5 ( Air = 1 )
Flash Point 49.00 °F. TCC ( 9.44 °C. )
logP (o/w) 1.380
Shelf Life 12.00 month(s) or longer if stored properly.
Storage refrigerate in tightly sealed containers.
Soluble in propylene glycol

Organoleptic Properties

Odor Description at 0.10 % in dipropylene glycol.

Safety Information

Preferred SDSView
European informationMost important hazard(s):
Oral/Parenteral Toxicityoral-rat LD50 7872 mg/kg
Dermal Toxicityskin-rabbit LD50 > 5000 mg/kg
Inhalation Toxicityinhalation-dog LCLo 41200 mg/m3/3H

GHS Classification

['GHS Classification in accordance with 29 CFR 1910 (OSHA HCS)', 'GHS Label elements, including precautionary statements', 'PERIPHERAL NERVE AND SENSATION: SPASTIC PARALYSIS WITH OR WITHOUT SENSORY CHANGE\nKIDNEY, URETER, AND BLADDER: CHANGES PRIMARILY IN GLOMERULI', 'BEHAVIORAL: SLEEP\nBEHAVIORAL: EXCITEMENT\nVASCULAR: BP LOWERING NOT CHARACTERIZED IN AUTONOMIC SECTION']

Safety in Use

Categorysubstances for use only as components of adhesives for food packaging, transporting, or holding food
IFRA Critical EffectDermal sensitization
Recommendation for methyl methacrylate usage levels up toPROHIBITED: Should not be used as a fragrance ingredient.
Maximised Survey-derived Daily Intakes (MSDI-EU)0.061 (μg/capita/day)
Modified Theoretical Added Maximum Daily Intake (mTAMDI)3900 (μg/person/day)
Threshold of Concern540 (μg/person/day)
Structure ClassII
baked goods-
beverages(nonalcoholic)2.00000
beverages(alcoholic)4.00000
breakfast cereal-
cheese-
chewing gum-
condiments / relishes-
confectionery froastings-
egg products-
fats / oils4.00000
fish products-
frozen dairy-
fruit ices2.00000
gelatins / puddings-
granulated sugar-
gravies-
hard candy-
imitation dairy-
instant coffee / tea-
jams / jellies-
meat products-
milk products2.00000
nut products-
other grains-
poultry-
processed fruits-
processed vegetables-
reconstituted vegetables-
seasonings / flavors-
snack foods-
soft candy-
soups-
sugar substitutes-
sweet sauces-
Dairy products, excluding products of category 02.0 (01.0)7.00000
Fats and oils, and fat emulsions (type water-in-oil) (02.0)5.00000
Edible ices, including sherbet and sorbet (03.0)10.00000
Processed fruit (04.1)7.00000
Processed vegetables (incl. mushrooms & fungi, roots & tubers, pulses and legumes), and nuts & seeds (04.2)-
Confectionery (05.0)10.00000
Chewing gum (05.3)-
Cereals and cereal products, incl. flours & starches from roots & tubers, pulses & legumes, excluding bakery (06.0)5.00000
Bakery wares (07.0)10.00000
Meat and meat products, including poultry and game (08.0)5.00000
Fish and fish products, including molluscs, crustaceans and echinoderms (MCE) (09.0)5.00000
Eggs and egg products (10.0)-
Sweeteners, including honey (11.0)-
Salts, spices, soups, sauces, salads, protein products, etc. (12.0)5.00000
Foodstuffs intended for particular nutritional uses (13.0)10.00000
Non-alcoholic ("soft") beverages, excl. dairy products (14.1)5.00000
Alcoholic beverages, incl. alcohol-free and low-alcoholic counterparts (14.2)10.00000
Ready-to-eat savouries (15.0)20.00000
Composite foods (e.g. casseroles, meat pies, mincemeat) - foods that could not be placed in categories 01.0 - 15.0 (16.0)5.00000

Penta International Corporation

Chemistry innovation

At Penta, our products and services help businesses do business better.

View All Website (973) 740-2300 lisaa@pentamfg.com

Sigma-Aldrich

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The perfect blend of products and services that bring your creativity to life.

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TCI AMERICA

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We continuously strive to advance our technology.

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WholeChem, LLC

Connecting Innovators To the Building Blocks Of the Universe

Custom manufacturer and distributor of specialty ingredients. We make global local.

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Potential Uses

None Found

Natural Occurrence

beef bread wheat bread wine

Synonyms

acrylic acid, 2-methyl-, methyl ester methacrylic acid methyl ester methacrylic acid, methyl ester 2-( methoxycarbonyl)-1-propene methyl 2-methyl propenoate methyl 2-methyl-2-propenoate methyl 2-methylacrylate methyl 2-methylprop-2-enoate methyl 2-methylpropenoate 2- methyl acrylic acid methyl ester methyl ester of methacrylic acid methyl methyl acrylate methyl-2-methyl-2-propenoate 2- methyl-2-propenoic acid methyl ester 2- methylacrylic acid methyl ester 2- methylacrylic acid, methyl ester 2- methylmethacrylate 2- propenoic acid, 2-methyl-, methyl ester PubMed: Determination of Carvedilol Enantiomers in Pharmaceutical Dosages by SBSE-HPLC Based on Diastereomer Formation. PubMed: Kinetic Study of Candida antarctica Lipase B Immobilization Using Poly(Methyl Methacrylate) Nanoparticles Obtained by Miniemulsion Polymerization as Support. PubMed: Synthesis and application of ion-imprinted polymer nanoparticles for the extraction and preconcentration of zinc ions. PubMed: Physicochemical and chromatographic characteristics of random amphiphilic copolymer aggregation in electrokinetic chromatography. PubMed: Antibacterial properties of tough and strong electrospun PMMA/PEO fiber mats filled with Lanasol--a naturally occurring brominated substance. PubMed: Characterisation and toxicological assessment of Neutral Methacrylate Copolymer for GRAS evaluation. PubMed: Color stability and flexural strength of poly (methyl methacrylate) and bis-acrylic composite based provisional crown and bridge auto-polymerizing resins exposed to beverages and food dye: an in vitro study. PubMed: Formation of poly(methyl methacrylate) thin films onto wool fiber surfaces by vapor deposition polymerization. PubMed: Assessment of methyl methacrylate genotoxicity by the micronucleus test. PubMed: Contemporary review of injectable facial fillers. PubMed: Signal detection and location-dependent noise in cone-beam computed tomography using the spatial definition of the Hotelling SNR. PubMed: Quantifying mixing using magnetic resonance imaging. PubMed: Preparing photochromic nanofibers and animal cells using a photochromic compound of 1',3',3'-trimethyl-6-nitrospiro (2H-1-benzopyran-2,2'-indoline). PubMed: Final report of the Cosmetic Ingredient Review Expert Panel safety assessment of polymethyl methacrylate (PMMA), methyl methacrylate crosspolymer, and methyl methacrylate/glycol dimethacrylate crosspolymer. PubMed: An alternative method for analysis of food taints using stir bar sorptive extraction. PubMed: Electrical percolation-based biosensor for real-time direct detection of staphylococcal enterotoxin B (SEB). PubMed: Effects of different food colorants and polishing techniques on color stability of provisional prosthetic materials. PubMed: Effects of different repolishing techniques on colour change of provisional prosthetic materials. PubMed: Histomorphometric and microchemical characterization of maturing dental enamel in rats fed a boron-deficient diet. PubMed: Precipitation as a simple and versatile method for preparation of optical nanochemosensors. PubMed: Sequential interpenetrating polymer networks produced from vegetable oil based polyurethane and poly(methyl methacrylate). PubMed: Physical properties of sequential interpenetrating polymer networks produced from canola oil-based polyurethane and poly(methyl methacrylate). PubMed: Optical resonance-enhanced absorption-based near-field immunochip biosensor for allergen detection. PubMed: PMMA particle-mediated DNA vaccine for cervical cancer. PubMed: Quantitative determination of amino acids in functional foods by microchip electrophoresis. PubMed: Modified capsular tension ring for cortical removal after implantation. PubMed: CE microchips: an opened gate to food analysis. PubMed: [Encapsulating hepatocytes with chitosan in physiological conditions]. PubMed: Assessment of methyl methacrylate vapor toxicity on the rat tracheal epithelium. PubMed: Characterization of amphoteric multilayered thin films by means of zeta potential measurements. PubMed: Gel trapping of dense colloids. PubMed: The electrochemical behaviour of ferrocene in a photocurable poly(methyl methacrylate-co-2-hydroxylethyl methacrylate) film for a glucose biosensor. PubMed: Controlled release of tebuconazole from a polymer matrix microparticle: release kinetics and length of efficacy. PubMed: Radical-scavenging activity of butylated hydroxytoluene (BHT) and its metabolites. PubMed: Advantages of using non-isothermal bioreactors in agricultural waste water treatment by means of immobilized urease. Study on the influence of spacer length and immobilization method. PubMed: Analysis for organic residues from aids to polymerization used to make plastics intended for food contact. PubMed: Excimer laser retreatment of residual myopia following photoastigmatic refractive keratectomy for compound myopic astigmatism. PubMed: Polymeric microcapsules of alachlor and metolachlor: preparation and evaluation of controlled-release properties. PubMed: The sensitization potential of methyl methacrylate and ethyl methacrylate. PubMed: A new adhesive bonding material for the cementation of implantable devices in otologic surgery. PubMed: Chronic inhalation toxicity and oncogenicity of methyl methacrylate in rats and hamsters. PubMed: Proton nuclear magnetic resonance spectroscopic detection and determination of ethylene glycol dimethacrylate as a contaminant of methyl methacrylate raw material. PubMed: Components of weasel and fox odors elicit fast wave bursts in the dentate gyrus of rats. PubMed: Optical performance of decentered monofocal intraocular lenses. PubMed: Optical quality testing of monofocal intraocular lens implants with a 3 mm and a 4 mm aperture. PubMed: On the clinical deformation of maxillary complete dentures. Influence of the processing techniques of acrylate-based polymers. PubMed: Dependence of curing time, peak temperature, and mechanical properties on the composition of bone cement. PubMed: [Reduction of the transfer of surface active agent residues in food]. PubMed: [Hygienic chemical studies on plastics (VIII). Migration test of methyl methacrylate and plastic additives from polymethyl methacrylate (author's transl)]. PubMed: [Hygienic chemical studies on plastics (VII). Determination of methyl methacrylate by gas chromatography (author's transl)]. PubMed: Container-derived contamination of maple sirup with methyl methacrylate, toluene, and styrene as determined by headspace gas-liquid chromatography. PubMed: Letter: Methyl methacrylate restrictions.