strombine

glycine, N-(carboxymethyl)-N-methyl- (9CI)

CAS: 4408-64-4 C5 H9 N O4 MW: 147.13053000

Identification

Namestrombine
IUPAC2-[carboxymethyl(methyl)amino]acetic acid
CAS Number4408-64-4
EINECS224-557-6
FDA UNIISH1YP5H4NA
Molecular FormulaC5 H9 N O4
Molecular Weight147.13053000
MDL NumberMFCD00004284
Nikkaji NumberJ135.883I
XlogP3-3.30 (est)

Regulatory

Physical Properties

Assay 95.00 to 100.00
Food Chemicals Codex Listed No
Boiling Point 332.80 °C. @ 760.00 mm Hg (est)
Flash Point 311.00 °F. TCC ( 155.10 °C. ) (est)
logP (o/w) -0.910 (est)
Soluble in water, 2.745e+005 mg/L @ 25 °C (est)

No sensory data available

Safety Information

Preferred SDSView
Oral/Parenteral ToxicityNot determined
Dermal ToxicityNot determined
Inhalation ToxicityNot determined

GHS Classification

['GHS Classification in accordance with 29 CFR 1910 (OSHA HCS)', 'GHS Label elements, including precautionary statements']

Safety in Use

Categorynatural substances and extractives
Recommendation for strombine usage levels up tonot for fragrance use.
Recommendation for strombine flavor usage levels up tonot for flavor use.

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Potential Uses

None Found

Natural Occurrence

crassostrea gigas PMC

Synonyms

methyl iminodiacetic acid methyliminodiacetic acid acetic acid, (methylimino)di- (8CI) glycine, N-(carboxymethyl)-N-methyl- (9CI) 2-[ carboxymethyl(methyl)amino]acetic acid MIDA PubMed: MIDA as a simple and highly efficient ligand for palladium-catalyzed Hiyama cross-coupling of aryl halides. PubMed: Site-differentiated polyboron arenes prepared by direct C-H borylation and their highly selective Suzuki-Miyaura cross-coupling reactions. PubMed: Synthesis of trans-2-(trifluoromethyl)cyclopropanes via Suzuki reactions with an N-methyliminodiacetic acid boronate. PubMed: Phylogenetic comparison of opine dehydrogenase sequences from marine invertebrates. PubMed: One-pot C-N/C-C cross-coupling of methyliminodiacetic acid boronyl arenes enabled by protective enolization. PubMed: Quaterpyridine ligands for panchromatic Ru(II) dye sensitizers. PubMed: Concise total synthesis of (-)-myxalamide A. PubMed: Oxidative Heck Reactions using Aryltrifluoroborates and Aryl N-Methyliminodiacetic Acid (MIDA) Boronates. PubMed: Exploring natural products for new taste sensations. PubMed: Identification of octopine dehydrogenase from Mytilus galloprovincialis. PubMed: Tandem Cycloisomerization/Suzuki Coupling of Arylethynyl MIDA Boronates. PubMed: Vibrational spectroscopy of N-methyliminodiacetic acid (MIDA)-protected boronate ester: examination of the B-N dative bond. PubMed: Synthesis and properties of MIDA boronate containing aromatic amino acids: new peptide building blocks. PubMed: Purification and kinetic characteristics of strombine dehydrogenase from the foot muscle of the hard clam (Meretrix lusoria). PubMed: Mobility of radionuclides in soil/groundwater system: comparing the influence of EDTA and four of its degradation products. PubMed: General method for synthesis of 2-heterocyclic N-methyliminodiacetic acid boronates. PubMed: Total synthesis of (-)-aurantioclavine. PubMed: Taste contribution of (R)-strombine to dried scallop. PubMed: Strombine dehydrogenase in the demosponge Suberites domuncula: characterization and kinetic properties of the enzyme crucial for anaerobic metabolism. PubMed: Photoinduced linkage isomerism of {RuNO}(6) complexes with bioligands and related chelators. PubMed: Phosphonate- and carboxylate-based chelating agents that solubilize (hydr)oxide-bound MnIII. PubMed: Purification, characterization, and cDNA cloning of opine dehydrogenases from the polychaete rockworm Marphysa sanguinea. PubMed: Ruthenium(III) triazacyclononane dithiocarbamate, pyridinecarboxylate, or aminocarboxylate complexes as scavengers of nitric oxide. PubMed: Ventilatory and metabolic responses to hypoxia and sulphide in the lugworm Arenicola marina (L.). PubMed: Resistance to freshwater exposure in White Sea Littorina spp. I: Anaerobic metabolism and energetics. PubMed: Improved HPLC determination of acidic opines by phenylisothiocyanate derivatization and its application to marine animals. PubMed: High-performance liquid chromatographic determination of the imino acids (opines) meso-alanopine and D-strombine in muscle extract of invertebrates. PubMed: Rapid Anaerobic Benzene Oxidation with a Variety of Chelated Fe(III) Forms. PubMed: Measurements of oxygen consumption in Mytilus edulis during exposure to, and recovery from, high sublethal concentrations of formaldehyde, benzene and phenol. PubMed: Physiological parameters in ecotoxicology. PubMed: Quantitative HPLC analysis of acidic opines by phenylthiocarbamyl derivatization. PubMed: Binding properties of aminopolycarboxylato ligands bound to cellulose. PubMed: The pyruvate branchpoint in the anaerobic energy metabolism of the jumping cockle Cardium tuberculatum L.: D-lactate formation during environmental anaerobiosis versus octopine formation during exercise. PubMed: Use of methyliminodiacetic acid bound to cellulose for preconcentration and determination of trace-metal cations. PubMed: The acute toxicity of Bimida, a prospective hepatobiliary scanning agent. PubMed: History. Development of new radiopharmaceuticals based on N-substitution of iminodiacetic acid. By Michael D. Loberg, Malcolm Cooper, Elizabeth Harvey, Patrick Callery, and William Faith. 1976. PubMed: High-performance liquid chromatographic separation and quantification of alanopine and strombine in crude tissue extracts. PubMed: Determination of meso-alanopine and D-strombine by high pressure liquid chromatography in extracts from marine invertebrates. PubMed: The anaerobic molluscan heart: adaptation to environmental anoxia. Comparison with energy metabolism in vertebrate hearts. PubMed: Multiple forms of octopine dehydrogenase in Strombus luhuanus (mollusca, gastropoda, strombidae): genetic basis of polymorphism, properties of the enzymes, and relationship between the octopine dehydrogenase phenotype and the accumulation of anaerobic end products during exercise. PubMed: Gas-liquid chromatography and enzymatic determination of alanopine and strombine in tissues of marine invertebrates. PubMed: Alanopine and strombine are novel imino acids produced by a dehydrogenase found in the adductor muscle of the oyster, Crassostrea gigas. PubMed: Tungsten vs. Molybdenum in models for biological systems. PubMed: Development of new radiopharmaceuticals based on N-substitution of iminodiacetic acid. PubMed: Biodegradation of nitrilotriacetic acid and related imino aand amino acids in river water.