mimosine
1(4H)-pyridinepropanoic acid, alpha-amino-3-hydroxy-4-oxo-, (alphaS)-
Identification
| Name | mimosine |
| IUPAC | (2S)-2-amino-3-(3-hydroxy-4-oxopyridin-1-yl)propanoic acid |
| CAS Number | 500-44-7 |
| EINECS | 207-905-1 |
| FDA UNII | Z46B1LUI5N |
| Molecular Formula | C8 H10 N2 O4 |
| Molecular Weight | 198.17850000 |
| MDL Number | MFCD00075909 |
| Nikkaji Number | J9.396C |
Regulatory
Physical Properties
| Assay | 95.00 to 100.00 |
| Food Chemicals Codex Listed | No |
| Melting Point | 225.00 to 226.00 °C. @ 760.00 mm Hg |
| Boiling Point | 428.60 °C. @ 760.00 mm Hg (est) |
| Flash Point | 415.00 °F. TCC ( 213.00 °C. ) (est) |
| logP (o/w) | -1.080 (est) |
| Soluble in | water, 1e+006 mg/L @ 25 °C (est) |
No sensory data available
Safety Information
| Preferred SDS | View |
| Oral/Parenteral Toxicity | Not determined |
| Dermal Toxicity | Not determined |
| Inhalation Toxicity | Not determined |
GHS Classification
['GHS Classification in accordance with 29 CFR 1910 (OSHA HCS)', 'GHS Label elements, including precautionary statements']
Safety in Use
| Category | natural substances and extractives |
| Recommendation for mimosine usage levels up to | not for fragrance use. |
| Recommendation for mimosine flavor usage levels up to | not for flavor use. |
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Potential Uses
Natural Occurrence
Synonyms
(2S)-2-
amino-3-(3-hydroxy-4-oxopyridin-1-yl)propanoic acid
(S)-alpha-
amino-3-hydroxy-4-oxo-1(4H)-pyridylpropionic acid
leucaenine
leucena glauca alpha-amino acid
leucenol
mimosin
1(4H)-
pyridinepropanoic acid, alpha-amino-3-hydroxy-4-oxo-, (alphaS)-
PubMed:
Non-protein amino acids in Australian acacia seed: Implications for food security and recommended processing methods to reduce djenkolic acid.
PubMed:
Endothelin-converting enzyme is a plausible target gene for hypoxia-inducible factor.
PubMed:
Antioxidant and tyrosinase inhibitory activities of flavonoids from Trifolium nigrescens Subsp. petrisavi.
PubMed:
Antioxidant activity and inhibitory effects of lead (Leucaena leucocephala) seed extracts against lipid oxidation in model systems.
PubMed:
Feeding potential of cassava (Manihot esculenta Crantz) peels ensiled with Leucaena leucocephala and Gliricidia sepium assessed with West African dwarf goats.
PubMed:
Solid-phase synthesis of mimosine tetrapeptides and their inhibitory activities on neuraminidase and tyrosinase.
PubMed:
Curcumin provides potential protection against the activation of hypoxia and prolyl 4-hydroxylase inhibitors on prostate-specific antigen expression in human prostate carcinoma cells.
PubMed:
Inhibition of melanosis formation in Pacific white shrimp by the extract of lead (Leucaena leucocephala) seed.
PubMed:
Inhibitory effect of mimosine on polyphenoloxidase from cephalothoraxes of Pacific white shrimp (Litopenaeus vannamei).
PubMed:
Coat condition of ringtailed lemurs, Lemur catta, at Berenty Reserve, Madagascar: II. Coat and tail alopecia associated with Leucaena leucocepahala, 2001-2006.
PubMed:
Resveratrol-mediated sensitisation to TRAIL-induced apoptosis depends on death receptor and mitochondrial signalling.
PubMed:
Do calcium-mediated cellular signalling pathways, prostaglandin E2 (PGE2), estrogen or progesterone receptor antagonists, or bacterial endotoxins affect bovine placental function in vitro?
PubMed:
Potential therapeutic applications of some antinutritional plant secondary metabolites.
PubMed:
Partial purification, characterization, and histochemical localization of fully latent desert truffle (Terfezia claveryi Chatin) polyphenol oxidase.
PubMed:
Enhancement of beta-glucosidase and beta-galactosidase of Trigonella foenum-graecum by exposure to the allelochemical mimosine.
PubMed:
Nutritional and economic benefits of Leucaena and Gliricidia as feed supplements for small ruminants in humid West Africa.
PubMed:
Mimosine degradation in calves fed a sole diet of Leucaena leucocephala in India.
PubMed:
An automated colorimetric method for mimosine in Leucaena leaves.
PubMed:
Determination of mimosine in soybean sauce.