No sensory data available
Potential Uses
antioxidants
skin conditioning
Natural Occurrence
not found in nature
Synonyms
(R)-2-
acetamido-3-mercaptopropanoic acid
(2R)-2-
acetamido-3-sulfanyl-propanoic acid
(2R)-2-
acetamido-3-sulfanylpropanoic acid
L-a-
acetamido-b-mercaptopropionic acid
L-alpha-
acetamido-beta-mercaptopropionic acid
laevo-alpha-
acetamido-beta-mercaptopropionic acid
acetilcisteina
acetyl cysteine
N-
acetyl-3-mercaptoalanine
N-
acetyl-L-(+)-cysteine
N-
acetyl-L-cysteine
acetyl-laevo-cysteine
N-
acetyl-laevo-cysteine
(R)-2-
acetylamino-3-mercaptopropanoic acid
(2R)-2-
acetylamino-3-sulfanylpropanoic acid
2-(
acetylamino)-3-mercaptopropionic acid
(2R)-2-(
acetylamino)-3-sulfanylpropanoic acid
acetylcysteine
acetylcysteinum
airbron
broncholysin
brunac
cysteine, N-(1-hydroxyethylidene)-, (Z)-
L-
cysteine, N-acetyl-
cysteine, N-acetyl-, L-
exomuc
fabrol
fluatox
fluimicil infantil
fluimucetin
fluimucil
flumucetin
fluprowit
inspir
LNAC
lysomucil
mercapturic acid
(R)-
mercapturic acid
mucofilin
mucolator
mucolyticum
mucolytikum lappe
mucomyst
mucosil
mucosolvin
mucret
NASGC
parvolex
respaire
tixair
PubMed:
Isoegomaketone induces apoptosis in SK-MEL-2Â human melanoma cells through mitochondrial apoptotic pathway via activating the PI3K/Akt pathway.
PubMed:
Sulforaphane induces apoptosis in T24 human urinary bladder cancer cells through a reactive oxygen species-mediated mitochondrial pathway: The involvement of endoplasmic reticulum stress and the Nrf2 signaling pathway.
PubMed:
Activation of JNK contributes to evodiamine-induced apoptosis and G2/M arrest in human colorectal carcinoma cells: a structure-activity study of evodiamine.
PubMed:
Isoorientin induces apoptosis and autophagy simultaneously by reactive oxygen species (ROS)-related p53, PI3K/Akt, JNK, and p38 signaling pathways in HepG2 cancer cells.
PubMed:
Ï-Hydroxyundec-9-enoic acid induces apoptosis through ROS-mediated endoplasmic reticulum stress in non-small cell lung cancer cells.
PubMed:
Chimaphilin induces apoptosis in human breast cancer MCF-7 cells through a ROS-mediated mitochondrial pathway.
PubMed:
Atmospheric gas plasma-induced ROS production activates TNF-ASK1 pathway for the induction of melanoma cancer cell apoptosis.
PubMed:
Ampelopsin induces cell growth inhibition and apoptosis in breast cancer cells through ROS generation and endoplasmic reticulum stress pathway.
PubMed:
Alternative Biomarkers of n-Hexane exposure: Characterization of aminoderived pyrroles and thiol-pyrrole conjugates in urine of rats exposed to 2,5-Hexanedione.
PubMed:
The role of oxidative stress in citreoviridin-induced DNA damage in human liver-derived HepG2 cells.
PubMed:
Sulforaphane induces reactive oxygen species-mediated mitotic arrest and subsequent apoptosis in human bladder cancer 5637 cells.
PubMed:
Oxidative stress contributes to gold nanoparticle-induced cytotoxicity in human tumor cells.
PubMed:
Aflatoxin G1-induced oxidative stress causes DNA damage and triggers apoptosis through MAPK signaling pathway in A549 cells.
PubMed:
Dose-dependent folic acid and memantine treatments promote synergistic or additive protection against Aβ(25-35) peptide-induced apoptosis in SH-SY5Y cells mediated by mitochondria stress-associated death signals.
PubMed:
Protective effects of 6-hydroxy-1-methylindole-3-acetonitrile on cisplatin-induced oxidative nephrotoxicity via Nrf2 inactivation.
PubMed:
Comparative analysis of ER stress response into HIV protease inhibitors: lopinavir but not darunavir induces potent ER stress response via ROS/JNK pathway.
PubMed:
Antiproliferative and apoptotic effects of spanish honeys.
PubMed:
Reactive oxygen species mediate tolfenamic acid-induced apoptosis in human colorectal cancer cells.
PubMed:
Reduced scytonemin isolated from Nostoc commune induces autophagic cell death in human T-lymphoid cell line Jurkat cells.
PubMed:
Modulation of antioxidant defense system by the dithiocarbamate fungicides Maneb and Zineb in Chinese hamster V79 cells and the role of N-acetyl-L-cysteine.
PubMed:
Determination of benzyl isothiocyanate metabolites in human plasma and urine by LC-ESI-MS/MS after ingestion of nasturtium (Tropaeolum majus L.).
PubMed:
γ-Tocotrienol induced cell cycle arrest and apoptosis via activating the Bax-mediated mitochondrial and AMPK signaling pathways in 3T3-L1 adipocytes.
PubMed:
Rats with metabolic syndrome resist the protective effects of N-acetyl l-cystein against impaired spermatogenesis induced by high-phosphorus/zinc-free diet.
PubMed:
Coumestrol induces senescence through protein kinase CKII inhibition-mediated reactive oxygen species production in human breast cancer and colon cancer cells.
PubMed:
Genotoxicity of 2-bromo-3'-chloropropiophenone.
PubMed:
Oxidative DNA damage is involved in ochratoxin A-induced G2 arrest through ataxia telangiectasia-mutated (ATM) pathways in human gastric epithelium GES-1 cells in vitro.
PubMed:
Foodomics platform for the assay of thiols in wines with fluorescence derivatization and ultra performance liquid chromatography mass spectrometry using multivariate statistical analysis.
PubMed:
Verrucarin A enhances TRAIL-induced apoptosis via NF-κB-mediated Fas overexpression.
PubMed:
Antagonistic effect of Pseudomonas graminis CPA-7 against foodborne pathogens in fresh-cut apples under simulated commercial conditions.
PubMed:
An iTRAQ-based mitoproteomics approach for profiling the nephrotoxicity mechanisms of ochratoxin A in HEK 293 cells.
PubMed:
Herbacetin induces apoptosis in HepG2 cells: Involvements of ROS and PI3K/Akt pathway.
PubMed:
Diallyl trisulfide induces apoptosis in human breast cancer cells through ROS-mediated activation of JNK and AP-1.
PubMed:
The chinese herbal decoction danggui buxue tang inhibits angiogenesis in a rat model of liver fibrosis.
PubMed:
Oleic acid and glucose regulate glucagon-like peptide 1 receptor expression in a rat pancreatic ductal cell line.
PubMed:
Platycodin D induces reactive oxygen species-mediated apoptosis signal-regulating kinase 1 activation and endoplasmic reticulum stress response in human breast cancer cells.
PubMed:
A role for virally induced reactive oxygen species in Kaposi's sarcoma herpesvirus tumorigenesis.
PubMed:
Crosstalk between endoplasmic reticulum stress and oxidative stress in apoptosis induced by α-tocopheryl succinate in human gastric carcinoma cells.
PubMed:
Beta-eleostearic acid induce apoptosis in T24 human bladder cancer cells through reactive oxygen species (ROS)-mediated pathway.
PubMed:
Diallyl trisulfide induces apoptosis of human basal cell carcinoma cells via endoplasmic reticulum stress and the mitochondrial pathway.
PubMed:
Ochratoxin A induces oxidative DNA damage and G1 phase arrest in human peripheral blood mononuclear cells in vitro.
PubMed:
Involvement of intracellular oxidative stress-sensitive pathway in phloxine B-induced photocytotoxicity in human T lymphocytic leukemia cells.
PubMed:
Isoobtusilactone A sensitizes human hepatoma Hep G2 cells to TRAIL-induced apoptosis via ROS and CHOP-mediated up-regulation of DR5.
PubMed:
Aminoacylase 1-catalysed deacetylation of bioactives epoxides mycotoxin-derived mercapturates; 3,4-epoxyprecocenes as models of cytotoxic epoxides.
PubMed:
Oxidative stress impairs HIF1α activation: a novel mechanism for increased vulnerability of steatotic hepatocytes to hypoxic stress.
PubMed:
Molecular mechanisms of apoptosis induction by 2-dodecylcyclobutanone, a radiolytic product of palmitic acid, in human lymphoma U937 cells.
PubMed:
Benzyl isothiocyanate (BITC) induces G2/M phase arrest and apoptosis in human melanoma A375.S2 cells through reactive oxygen species (ROS) and both mitochondria-dependent and death receptor-mediated multiple signaling pathways.
PubMed:
Echinacea alkamides prevent lipopolysaccharide/D-galactosamine-induced acute hepatic injury through JNK pathway-mediated HO-1 expression.
PubMed:
Ginsenoside Rb1 inhibits cell activation and liver fibrosis in rat hepatic stellate cells.
PubMed:
Exopolysaccharide of Laetiporus sulphureus var. miniatus downregulates LPS-induced production of NO, PGEâ, and TNF-α in BV2 microglia cells via suppression of the NF-κB pathway.
PubMed:
Protective effect of N-acetyl-L-cysteine against maneb induced oxidative and apoptotic injury in Chinese hamster V79 cells.
PubMed:
L-cysteine, N-acetyl-L-cysteine, and glutathione protect Xenopus laevis embryos against acrylamide-induced malformations and mortality in the frog embryo teratogenesis assay.
PubMed:
Quercetin Prevents Unloading-Derived Disused Muscle Atrophy by Attenuating the Induction of Ubiquitin Ligases in Tail-Suspension Mice.
PubMed:
Surface treatments and coatings to maintain fresh-cut mango quality in storage.
PubMed:
Resveratrol, a dietary polyphenolic phytoalexin, is a functional scavenger of peroxynitrite.
PubMed:
6-dehydrogingerdione sensitizes human hepatoblastoma Hep G2 cells to TRAIL-induced apoptosis via reactive oxygen species-mediated increase of DR5.
PubMed:
Proteinaceous cytotoxic component of Allium sativum induces apoptosis of INT-407 intestinal cells.
PubMed:
Studies of acetaminophen and metabolites in urine and their correlations with toxicity using metabolomics.
PubMed:
(-)-Epigallocatechin-3-gallate induces apoptosis of human hepatoma cells by mitochondrial pathways related to reactive oxygen species.
PubMed:
Exercise-induced elevation in plasma oxidative generating capability augments the temporal inflammatory response stimulated by lipopolysaccharide.
PubMed:
Synthesis and characterization of mercapturic acid (N-acetyl-L-cysteine)-aflatoxin B1 adduct and its quantitation in rat urine by an enzyme immunoassay.
PubMed:
Phenethyl isothiocyanate inhibits STAT3 activation in prostate cancer cells.
PubMed:
Improving the quality of fresh-cut apples, pears, and melons using natural additives.
PubMed:
The effects of green tea (-)-epigallocatechin-3-gallate on reactive oxygen species in 3T3-L1 preadipocytes and adipocytes depend on the glutathione and 67 kDa laminin receptor pathways.
PubMed:
Advances in protein-amino acid nutrition of poultry.
PubMed:
Comparative study on essential oils incorporated into an alginate-based edible coating to assure the safety and quality of fresh-cut Fuji apples.
PubMed:
Characterization of covalent addition products of chlorogenic acid quinone with amino acid derivatives in model systems and apple juice by high-performance liquid chromatography/electrospray ionization tandem mass spectrometry.
PubMed:
Identification of Genes Responding to Low-Dose Arsenite Using HiCEP.
PubMed:
Effects of antioxidants on cancer prevention and neuromotor performance in Atm deficient mice.
PubMed:
Modifying effects of dietary factors on (-)-epigallocatechin-3-gallate-induced pro-matrix metalloproteinase-7 production in HT-29 human colorectal cancer cells.
PubMed:
Cytoprotective effects of selenium on cadmium-induced LLC-PK1 cells apoptosis by activating JNK pathway.
PubMed:
Areca nut extract suppresses T-cell activation and interferon-gamma production via the induction of oxidative stress.
PubMed:
Isoobtusilactone A-induced apoptosis in human hepatoma Hep G2 cells is mediated via increased NADPH oxidase-derived reactive oxygen species (ROS) production and the mitochondria-associated apoptotic mechanisms.
PubMed:
Oxidative DNA damage induced by Ochratoxin A in the HK-2 human kidney cell line: evidence of the relationship with cytotoxicity.
PubMed:
N-acetylcysteine is a highly available precursor for cysteine in the neonatal piglet receiving parenteral nutrition.
PubMed:
Reactive oxygen species mediate shear stress-induced fluid-phase endocytosis in vascular endothelial cells.
PubMed:
Involvement of reactive oxygen species in the immunosuppressive effect of 3-amino-1,4-dimethyl-5H-pyrido[4,3-b]indole (Trp-P-1), a food-born carcinogenic heterocyclic amine.
PubMed:
Triacylglycerol-mediated oxidative stress inhibits nitric oxide production in rat isolated hepatocytes.
PubMed:
Induction of quinone reductase by sulforaphane and sulforaphane N-acetylcysteine conjugate in murine hepatoma cells.
PubMed:
Effect of sulforaphane on metallothionein expression and induction of apoptosis in human hepatoma HepG2 cells.
PubMed:
(-)-Epigallocatechin-3-gallate promotes pro-matrix metalloproteinase-7 production via activation of the JNK1/2 pathway in HT-29 human colorectal cancer cells.
PubMed:
Induction of apoptosis by the Anthocyanidins through regulation of Bcl-2 gene and activation of c-Jun N-terminal kinase cascade in hepatoma cells.
PubMed:
Acrylonitrile-induced toxicity and oxidative stress in isolated rat colonocytes.
PubMed:
Hot-water extracts from adzuki beans (Vigna angularis) suppress not only the proliferation of KATO III cells in culture but also benzo(a)pyrene-induced tumorigenesis in mouse forestomatch.
PubMed:
Tumor profile of novel p53 heterozygous Tg.AC (v-Ha-ras) bitransgenic mice treated with benzo(a)pyrene and fed dietary N-acetyl-L-cysteine (NAC).
PubMed:
Conjugated linoleic acid--mediated apoptosis in Jurkat T cells involves the production of reactive oxygen species.
PubMed:
Oxidative DNA damage and glioma cell death induced by tetrahydropapaveroline.
PubMed:
Synthesis of isothiocyanate-derived mercapturic acids.
PubMed:
Differential activation of MAPK and ICE/Ced-3 protease in chemical-induced apoptosis. The role of oxidative stress in the regulation of mitogen-activated protein kinases (MAPKs) leading to gene expression and survival or activation of caspases leading to apoptosis.
PubMed:
The role of oxidative stress in the ochratoxin A-mediated toxicity in proximal tubular cells.
PubMed:
In vitro effect of bioactive compounds on influenza virus specific B- and T-cell responses.
PubMed:
Induction of xenobiotic enzymes by the MAP kinase pathway and the antioxidant or electrophile response element (ARE/EpRE).
PubMed:
Molecular mechanisms of butylated hydroxylanisole-induced toxicity: induction of apoptosis through direct release of cytochrome c.
PubMed:
Electrophilic properties of patulin. N-acetylcysteine and glutathione adducts.
PubMed:
Apoptosis induced by chelation of intracellular zinc is associated with depletion of cellular reduced glutathione level in rat hepatocytes.
PubMed:
Effects of L-cysteine and N-acetyl-L-cysteine on 4-hydroxy-2, 5-dimethyl-3(2H)-furanone (furaneol), 5-(hydroxymethyl)furfural, and 5-methylfurfural formation and browning in buffer solutions containing either rhamnose or glucose and arginine.
PubMed:
Arecoline cytotoxicity on human oral mucosal fibroblasts related to cellular thiol and esterase activities.
PubMed:
Involvement of hydrogen peroxide and hydroxyl radical in chemically induced apoptosis of HL-60 cells.
PubMed:
Butylated hydroxyanisole and its metabolite tert-butylhydroquinone differentially regulate mitogen-activated protein kinases. The role of oxidative stress in the activation of mitogen-activated protein kinases by phenolic antioxidants.
PubMed:
Inhibitory effect of sulfur-containing amino acids on burnt off-flavours in canned liver sausages.
PubMed:
Curcumin, an antioxidant and anti-tumor promoter, induces apoptosis in human leukemia cells.
PubMed:
Effects of curcumin on cytochrome P450 and glutathione S-transferase activities in rat liver.
PubMed:
Role of glutathione redox cycle in TNF-alpha-mediated endothelial cell dysfunction.
PubMed:
Separation of enantiomers of N-acetylcysteine by capillary electrophoresis after derivatization by o-phthaldialdehyde.
PubMed:
Bioavailable level and source of cysteine determine protein quality of a commercial enteral product: adequacy of tryptophan but deficiency of cysteine for rats fed an enteral product prepared fresh or stored beyond shelf life.
PubMed:
High-performance liquid chromatographic resolution of (R, S)-α-alkyl-α-amino acids as diastereomeric derivatives.
PubMed:
Browning prevention in fresh and dehydrated potatoes by SH-containing amino acids.
PubMed:
Automated enantioseparation of amino acids by derivatization with o-phthaldialdehyde and n-acylated cysteines.
PubMed:
The utilization and safety of isomeric sulfur-containing amino acids in mice.
PubMed:
Inactivation of aflatoxin B1 mutagenicity by thiols.