N-alpha-acetyl-laevo-lysine
L-lysine, N2-acetyl-
Identification
| Name | N-alpha-acetyl-laevo-lysine |
| CAS Number | 1946-82-3 |
| EINECS | 217-747-5 |
| FDA UNII | 7D44E6BN1B |
| Molecular Formula | C8 H16 N2 O3 |
| Molecular Weight | 188.22712000 |
| MDL Number | MFCD00008233 |
| Nikkaji Number | J142.027E |
| XlogP3 | -4.40 (est) |
Regulatory
Physical Properties
| Assay | 95.00 to 100.00 |
| Food Chemicals Codex Listed | No |
| Soluble in | water, 8037 mg/L @ 25 °C (est) |
No sensory data available
Safety Information
| Preferred SDS | View |
| Oral/Parenteral Toxicity | Not determined |
| Dermal Toxicity | Not determined |
| Inhalation Toxicity | Not determined |
GHS Classification
['GHS Classification in accordance with 29 CFR 1910 (OSHA HCS)', 'GHS Label elements, including precautionary statements']
Safety in Use
| Category | information only not used for fragrances or flavors |
| Recommendation for N-alpha-acetyl-laevo-lysine usage levels up to | not for fragrance use. |
| Recommendation for N-alpha-acetyl-laevo-lysine flavor usage levels up to | not for flavor use. |
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Potential Uses
Natural Occurrence
Synonyms
(2S)-2-
acetamido-6-aminohexanoic acid
N-alpha-
acetyl-L-lysine
L-
lysine, N2-acetyl-
PubMed:
Photoexchange products of cytosine and 5-methylcytosine with N alpha-acetyl-L-lysine and L-lysine
PubMed:
An aminoacylase activity from Streptomyces ambofaciens catalyzes the acylation of lysine on à-position and peptides on N-terminal position
PubMed:
Characterization of Nalpha-benzyloxycarbonyl-L-lysine oxidizing enzyme from Rhodococcus sp. AIU Z-35-1
PubMed:
A novel crosslinked type of advanced glycation end-product derived from lactaldehyde
PubMed:
Identification of a novel advanced glycation end product derived from lactaldehyde
PubMed:
Synthesis of N alpha-[3H]acetyl-L-lysine chloromethyl ketone and its use in the fluorographic detection of proteases
PubMed:
Studies on the reaction of trans-2-heptenal with peanut proteins
PubMed:
Comparison of the reaction of methylglyoxal (MGO) with murine and human amyloid beta (A?): Insights into a mechanism of Alzheimer's disease (AD)
PubMed:
Identification and Quantitation of the Lipation Product 2-Amino-6-(3-methylpyridin-1-ium-1-yl)hexanoic Acid (MP-Lysine) in Peanuts
PubMed:
Capillary electrophoretic separation by double-strand polyaniline-coate capillaries of the advanced glycation endproducts formed from N-alpha-acetyl-L-lysine with reducing sug
PubMed:
Biomonitoring of heat-induced food contaminants: Quantitative analysis of furan dependent glutathione- and lysine-adducts in rat urine as putative biomarkers of exposure
PubMed:
Intestinal absorption of amino acid derivatives: importance of the free alpha-amino group
PubMed:
Role of CYP3A in isoniazid metabolism in vivo
PubMed:
Analysis of proteases involved in phagocytic activity of macrophages through the use of various amino acid esters
PubMed:
Compatibility of intravenous fat emulsions with prodrug amino acids
PubMed:
Ligand interactions with the kringle 5 domain of plasminogen. A study by 1H NMR spectroscopy
PubMed:
A sensitive colorimetric method for the measurement of serum C1 inactivator using the substrate N-alpha-acetyl-L-lysine methyl ester
PubMed:
Synthesis of sulfonamides with effective inhibitory action against Porphyromonas gingivalis ?-carbonic anhydrase
PubMed:
Structural elucidation of T-2 toxin thermal degradation products and investigations toward their occurrence in retail food
PubMed:
Ascorbic acid glycation: the reactions of L-threose in lens tissue
PubMed:
Isolation and initial characterization of tumoricidal monokine(s) from the human monocytic leukemia cell line THP-1
PubMed:
Chemical and biological explorations of the electrophilic reactivity of the bioactive marine natural product halenaquinone with biomimetic nucleophiles
PubMed:
Bound fumonisin B1: analysis of fumonisin-B1 glyco and amino acid conjugates by liquid chromatography-electrospray ionization-tandem mass spectrometry
PubMed:
Sulfonamides with Potent Inhibitory Action and Selectivity against the à-Carbonic Anhydrase from Vibrio cholerae
PubMed:
4-Hydroxy-2-nonenal (4-HNE) and Its Lipation Product 2-Pentylpyrrole Lysine (2-PPL) in Peanuts
PubMed:
The degradation of L-threose at Maillard reaction conditions
PubMed:
pH dependency of the carboxyl oxygen exchange reaction catalyzed by lysyl endopeptidase and trypsin
PubMed:
New series of sulfonamides containing amino acid moiety act as effective and selective inhibitors of tumor-associated carbonic anhydrase XII
PubMed:
Formaldehyde replacement with glyoxylic acid in semipermanent hair straightening: a new and multidisciplinary investigation
PubMed:
Reactions of a modified lysine with aldehydic and diketonic dicarbonyl compounds: an electrospray mass spectrometry structure/activity study
PubMed:
Kinetics of formation of fluorescent products from hexanal and L-lysine in a two-phase system
PubMed:
Structural and functional characterization of pronyl-lysine, a novel protein modification in bread crust melanoidins showing in vitro antioxidative and phase I/II enzyme modul
PubMed:
Characterization of amino acid and glutathione adducts of cis-2-butene-1,4-dial, a reactive metabolite of furan
PubMed:
Contact activation triggers stimulation of the monocyte 5-lipoxygenase pathway via plasmin
PubMed:
Isolation and characterization of the major serum albumin adduct formed by aflatoxin B1 in vivo in rats
PubMed:
The reversible reaction of protein amino groups with exo-cis-3,6-endoxo-delta-tetrahydrophthalic anhydride
PubMed:
Direct oxidation and covalent binding of isoniazid to rodent liver and human hepatic microsomes: humans are more like mice than rats
PubMed:
Triosidines: novel Maillard reaction products and cross-links from the reaction of triose sugars with lysine and arginine residues
PubMed:
Antibodies to dopamine: radioimmunological study of specificity in relation to immunocytochemistry
PubMed:
Covalent crosslinking of neurofilament proteins by oxidized catechols as a potential mechanism of Lewy body formation
PubMed:
1H NMR studies of aliphatic ligand binding to human plasminogen kringle 4
PubMed:
Identification of an aflatoxin G1-serum albumin adduct and its relevance to the measurement of human exposure to aflatoxins
PubMed:
Glyceraldehyde-derived advanced glycation end-products having pyrrolopyridinium-based crosslinks
PubMed:
Studies on the formation of lysinomethylalanine and histidinomethylalanine in milk products
PubMed:
Antisera against catecholamines: specificity studies and physicochemical data for anti-dopamine and anti-p-tyramine antibodies
PubMed:
Urokinase bound to fibrocollagenous tubes: an in vitro kinetic study
PubMed:
Biotransformation of the aerosol propellant 1,1,1,2,3,3,3-heptafluoropropane (HFA-227): lack of protein binding of the metabolite hexafluoroacetone
PubMed:
Effect of theanine and polyphenols enriched fractions from decaffeinated tea dust on the formation of Maillard reaction products and sensory attributes of breads
PubMed:
Kinetic studies on soluble and insoluble urokinases
PubMed:
Purification and some properties of factor D of the human properdin system
PubMed:
Fibrinolytic activity of immobilized plasminogen activator
PubMed:
Cytochrome P4502C11 is a target of diclofenac covalent binding in rats
PubMed:
Characterization of the low-field proton magnetic resonance spectrum of plasminogen kringle 4 via selective Overhauser experiments in 1H2O
PubMed:
The inhibition of urokinase by aromatic diamidines
PubMed:
1H-NMR spectroscopic manifestations of ligand binding to the kringle 4 domain of human plasminogen
PubMed:
Analysis of ligand-binding to the kringle 4 fragment from human plasminogen
PubMed:
Inhibition of the Na+/glucose cotransporter functional lysyl residues by 4-(4-methoxy-3-sulfophenyl)-2,6-bis(4-sulfophenyl)pyryl ium