N-alpha-acetyl-laevo-lysine

L-lysine, N2-acetyl-

CAS: 1946-82-3 C8 H16 N2 O3 MW: 188.22712000

Identification

NameN-alpha-acetyl-laevo-lysine
CAS Number1946-82-3
EINECS217-747-5
FDA UNII7D44E6BN1B
Molecular FormulaC8 H16 N2 O3
Molecular Weight188.22712000
MDL NumberMFCD00008233
Nikkaji NumberJ142.027E
XlogP3-4.40 (est)

Regulatory

Physical Properties

Assay 95.00 to 100.00
Food Chemicals Codex Listed No
Soluble in water, 8037 mg/L @ 25 °C (est)

No sensory data available

Safety Information

Preferred SDSView
Oral/Parenteral ToxicityNot determined
Dermal ToxicityNot determined
Inhalation ToxicityNot determined

GHS Classification

['GHS Classification in accordance with 29 CFR 1910 (OSHA HCS)', 'GHS Label elements, including precautionary statements']

Safety in Use

Categoryinformation only not used for fragrances or flavors
Recommendation for N-alpha-acetyl-laevo-lysine usage levels up tonot for fragrance use.
Recommendation for N-alpha-acetyl-laevo-lysine flavor usage levels up tonot for flavor use.

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Potential Uses

None Found

Natural Occurrence

not found in nature

Synonyms

(2S)-2- acetamido-6-aminohexanoic acid N-alpha- acetyl-L-lysine L- lysine, N2-acetyl- PubMed: Photoexchange products of cytosine and 5-methylcytosine with N alpha-acetyl-L-lysine and L-lysine PubMed: An aminoacylase activity from Streptomyces ambofaciens catalyzes the acylation of lysine on à-position and peptides on N-terminal position PubMed: Characterization of Nalpha-benzyloxycarbonyl-L-lysine oxidizing enzyme from Rhodococcus sp. AIU Z-35-1 PubMed: A novel crosslinked type of advanced glycation end-product derived from lactaldehyde PubMed: Identification of a novel advanced glycation end product derived from lactaldehyde PubMed: Synthesis of N alpha-[3H]acetyl-L-lysine chloromethyl ketone and its use in the fluorographic detection of proteases PubMed: Studies on the reaction of trans-2-heptenal with peanut proteins PubMed: Comparison of the reaction of methylglyoxal (MGO) with murine and human amyloid beta (A?): Insights into a mechanism of Alzheimer's disease (AD) PubMed: Identification and Quantitation of the Lipation Product 2-Amino-6-(3-methylpyridin-1-ium-1-yl)hexanoic Acid (MP-Lysine) in Peanuts PubMed: Capillary electrophoretic separation by double-strand polyaniline-coate capillaries of the advanced glycation endproducts formed from N-alpha-acetyl-L-lysine with reducing sug PubMed: Biomonitoring of heat-induced food contaminants: Quantitative analysis of furan dependent glutathione- and lysine-adducts in rat urine as putative biomarkers of exposure PubMed: Intestinal absorption of amino acid derivatives: importance of the free alpha-amino group PubMed: Role of CYP3A in isoniazid metabolism in vivo PubMed: Analysis of proteases involved in phagocytic activity of macrophages through the use of various amino acid esters PubMed: Compatibility of intravenous fat emulsions with prodrug amino acids PubMed: Ligand interactions with the kringle 5 domain of plasminogen. A study by 1H NMR spectroscopy PubMed: A sensitive colorimetric method for the measurement of serum C1 inactivator using the substrate N-alpha-acetyl-L-lysine methyl ester PubMed: Synthesis of sulfonamides with effective inhibitory action against Porphyromonas gingivalis ?-carbonic anhydrase PubMed: Structural elucidation of T-2 toxin thermal degradation products and investigations toward their occurrence in retail food PubMed: Ascorbic acid glycation: the reactions of L-threose in lens tissue PubMed: Isolation and initial characterization of tumoricidal monokine(s) from the human monocytic leukemia cell line THP-1 PubMed: Chemical and biological explorations of the electrophilic reactivity of the bioactive marine natural product halenaquinone with biomimetic nucleophiles PubMed: Bound fumonisin B1: analysis of fumonisin-B1 glyco and amino acid conjugates by liquid chromatography-electrospray ionization-tandem mass spectrometry PubMed: Sulfonamides with Potent Inhibitory Action and Selectivity against the à-Carbonic Anhydrase from Vibrio cholerae PubMed: 4-Hydroxy-2-nonenal (4-HNE) and Its Lipation Product 2-Pentylpyrrole Lysine (2-PPL) in Peanuts PubMed: The degradation of L-threose at Maillard reaction conditions PubMed: pH dependency of the carboxyl oxygen exchange reaction catalyzed by lysyl endopeptidase and trypsin PubMed: New series of sulfonamides containing amino acid moiety act as effective and selective inhibitors of tumor-associated carbonic anhydrase XII PubMed: Formaldehyde replacement with glyoxylic acid in semipermanent hair straightening: a new and multidisciplinary investigation PubMed: Reactions of a modified lysine with aldehydic and diketonic dicarbonyl compounds: an electrospray mass spectrometry structure/activity study PubMed: Kinetics of formation of fluorescent products from hexanal and L-lysine in a two-phase system PubMed: Structural and functional characterization of pronyl-lysine, a novel protein modification in bread crust melanoidins showing in vitro antioxidative and phase I/II enzyme modul PubMed: Characterization of amino acid and glutathione adducts of cis-2-butene-1,4-dial, a reactive metabolite of furan PubMed: Contact activation triggers stimulation of the monocyte 5-lipoxygenase pathway via plasmin PubMed: Isolation and characterization of the major serum albumin adduct formed by aflatoxin B1 in vivo in rats PubMed: The reversible reaction of protein amino groups with exo-cis-3,6-endoxo-delta-tetrahydrophthalic anhydride PubMed: Direct oxidation and covalent binding of isoniazid to rodent liver and human hepatic microsomes: humans are more like mice than rats PubMed: Triosidines: novel Maillard reaction products and cross-links from the reaction of triose sugars with lysine and arginine residues PubMed: Antibodies to dopamine: radioimmunological study of specificity in relation to immunocytochemistry PubMed: Covalent crosslinking of neurofilament proteins by oxidized catechols as a potential mechanism of Lewy body formation PubMed: 1H NMR studies of aliphatic ligand binding to human plasminogen kringle 4 PubMed: Identification of an aflatoxin G1-serum albumin adduct and its relevance to the measurement of human exposure to aflatoxins PubMed: Glyceraldehyde-derived advanced glycation end-products having pyrrolopyridinium-based crosslinks PubMed: Studies on the formation of lysinomethylalanine and histidinomethylalanine in milk products PubMed: Antisera against catecholamines: specificity studies and physicochemical data for anti-dopamine and anti-p-tyramine antibodies PubMed: Urokinase bound to fibrocollagenous tubes: an in vitro kinetic study PubMed: Biotransformation of the aerosol propellant 1,1,1,2,3,3,3-heptafluoropropane (HFA-227): lack of protein binding of the metabolite hexafluoroacetone PubMed: Effect of theanine and polyphenols enriched fractions from decaffeinated tea dust on the formation of Maillard reaction products and sensory attributes of breads PubMed: Kinetic studies on soluble and insoluble urokinases PubMed: Purification and some properties of factor D of the human properdin system PubMed: Fibrinolytic activity of immobilized plasminogen activator PubMed: Cytochrome P4502C11 is a target of diclofenac covalent binding in rats PubMed: Characterization of the low-field proton magnetic resonance spectrum of plasminogen kringle 4 via selective Overhauser experiments in 1H2O PubMed: The inhibition of urokinase by aromatic diamidines PubMed: 1H-NMR spectroscopic manifestations of ligand binding to the kringle 4 domain of human plasminogen PubMed: Analysis of ligand-binding to the kringle 4 fragment from human plasminogen PubMed: Inhibition of the Na+/glucose cotransporter functional lysyl residues by 4-(4-methoxy-3-sulfophenyl)-2,6-bis(4-sulfophenyl)pyryl ium