N-hydroxysuccinimide

2,5-pyrrolidinedione, 1-hydroxy-

CAS: 6066-82-6 C4 H5 N O3 MW: 115.08845000

Identification

NameN-hydroxysuccinimide
CAS Number6066-82-6
EINECS228-001-3
FDA UNIIMJE3791M4T
Molecular FormulaC4 H5 N O3
Molecular Weight115.08845000
MDL NumberMFCD00005516
Nikkaji NumberJ26.034G
Beilstein0113913
XlogP3-1.40 (est)

Regulatory

Physical Properties

Assay 95.00 to 100.00
Food Chemicals Codex Listed No
Boiling Point 262.40 °C. @ 760.00 mm Hg (est)
Flash Point 235.00 °F. TCC ( 112.50 °C. ) (est)
logP (o/w) -2.000 (est)
Soluble in water, 1e+006 mg/L @ 25 °C (est)

Cosmetic Information

CosIngcosmetic data
Cosmetic Usesskin conditioning

No sensory data available

Safety Information

Preferred SDSView
Oral/Parenteral ToxicityNot determined
Dermal ToxicityNot determined
Inhalation ToxicityNot determined

GHS Classification

['GHS Classification in accordance with 29 CFR 1910 (OSHA HCS)', 'GHS Label elements, including precautionary statements']

Safety in Use

Categorycosmetic ingredient for skin conditioning
Recommendation for N-hydroxysuccinimide usage levels up tonot for fragrance use.
Recommendation for N-hydroxysuccinimide flavor usage levels up tonot for flavor use.

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Potential Uses

None Found

Natural Occurrence

not found in nature

Synonyms

1- hydroxy-2,5-pyrrolidinedione 1- hydroxypyrrolidine-2,5-dione 1- hydroxysuccinimide 2,5- pyrrolidinedione, 1-hydroxy- succinimide, N-hydroxy- (8CI) PubMed: Synthesis, labeling and bioanalytical applications of a tris(2,2'-bipyridyl)ruthenium(II)-based electrochemiluminescence probe. PubMed: Decoration of silk fibroin by click chemistry for biomedical application. PubMed: Preparation and characterization of albumin conjugates of a truncated peptide YY analogue for half-life extension. PubMed: Quantum dot loaded liposomes as fluorescent labels for immunoassay. PubMed: Site-specific DOTA/europium-labeling of recombinant human relaxin-3 for receptor-ligand interaction studies. PubMed: Photoabsorption and resonance energy transfer phenomenon in CdTe-protein bioconjugates: an insight into QD-biomolecular interactions. PubMed: Development of an ionic liquid-based ultrasonic-assisted liquid-liquid microextraction method for sensitive determination of biogenic amines: application to the analysis of octopamine, tyramine and phenethylamine in beer samples. PubMed: Conjugation behaviours of CdTe quantum dots and antibody by a novel immunochromatographic method. PubMed: Fluorescent identification and detection of Staphylococcus aureus with carboxymethyl chitosan/CdS quantum dots bioconjugates. PubMed: Bioconjugation of CdTe quantum dot for the detection of 2,4-dichlorophenoxyacetic acid by competitive fluoroimmunoassay based biosensor. PubMed: Enzyme immunoassay for mycophenolic acid in milk and cheese. PubMed: EDC/NHS-crosslinked type II collagen-chondroitin sulfate scaffold: characterization and in vitro evaluation. PubMed: Detection of deoxynivalenol based on a single-chain fragment variable of the antideoxynivalenol antibody. PubMed: Measurement of triclosan in water using a magnetic particle enzyme immunoassay. PubMed: Regulatory effect of amino acids on the pasting behavior of potato starch is attributable to its binding to the starch chain. PubMed: Survival of baboon biotin-X-N-hydroxysuccinimide and (111)In-oxine-labelled autologous fresh and lyophilized reconstituted platelets. PubMed: Development of antibodies for the detection of N-acetyl-glufosinate. PubMed: Development of an enzyme-linked immunosorbent assay for the detection of the organophosphorus insecticide acephate. PubMed: Purification of TAXI-like endoxylanase inhibitors from wheat (Triticum aestivum L.) whole meal reveals a family of iso-forms. PubMed: Development of an immunoassay for the residues of the herbicide bensulfuron-methyl. PubMed: Preparation of specific antisera to 15alpha-hydroxyestrogens.