N-phenyl-2-naphthyl amine

neozone

CAS: 135-88-6 C16 H13 N MW: 219.28661000

Identification

NameN-phenyl-2-naphthyl amine
CAS Number135-88-6
EINECS205-223-9
FDA UNII456KT854AJ
Molecular FormulaC16 H13 N
Molecular Weight219.28661000
MDL NumberMFCD00004052
Nikkaji NumberJ3.627G
Beilstein2211188
XlogP35.10 (est)

Regulatory

FDA Mainterm (IAUFC)135-88-6 ; PHENYL-BETA-NAPHTHYLAMINE (FREE OF BETA-NAPHTHYLAMINE)

Physical Properties

Appearance light gray to gray powder (est)
Assay 95.00 to 100.00
Food Chemicals Codex Listed No
Soluble in water, 6.311 mg/L @ 25 °C (est)

No sensory data available

Safety Information

Preferred SDSView
Oral/Parenteral Toxicityoral-mouse LD50 1450 mg/kg
Dermal ToxicityNot determined
Inhalation ToxicityNot determined

GHS Classification

['GHS Classification in accordance with 29 CFR 1910 (OSHA HCS)', 'GHS Label elements, including precautionary statements']

Safety in Use

Categorynatural substances and extractives
Recommendation for N-phenyl-2-naphthyl amine usage levels up tonot for fragrance use.
Recommendation for N-phenyl-2-naphthyl amine flavor usage levels up tonot for flavor use.

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Potential Uses

None Found

Natural Occurrence

carrot

Synonyms

2- anilinonaphthalene 2- naphthylamine, N-phenyl- beta- naphthylphenylamine neozone neozone D phenyl-2-naphthylamine N- phenyl-2-naphthylamine phenyl-beta-naphtilamine 2- phenylaminonaphthalene N- phenylnaphthalen-2-amine PubMed: Quantification of N-phenyl-2-naphthylamine by gas chromatography and isotope-dilution mass spectrometry and its percutaneous absorption ex vivo under workplace conditions. PubMed: Comparative biotoxicity of N-Phenyl-1-naphthylamine and N-Phenyl-2-naphthylamine on cyanobacteria Microcystis aeruginosa. PubMed: Induction of Strong Long-Lived Room-Temperature Phosphorescence of N-Phenyl-2-naphthylamine Molecules by Confinement in a Crystalline Dibromobiphenyl Matrix. PubMed: [Secretion of Phenolic Compounds into Root Exudates of Pea Seedlings upon Inoculation with Rhizobium leguminosarum bv. viceae or Pseudomonas siringae pv. Pisi]. PubMed: Pollution-Induced Community Tolerance To Diagnose Hazardous Chemicals in Multiple Contaminated Aquatic Systems. PubMed: A toxicokinetic study of specifically acting and reactive organic chemicals for the prediction of internal effect concentrations in Scenedesmus vacuolatus. PubMed: Metabolic dephenylation of the rubber antioxidant N-phenyl-2-naphthylamine to carcinogenic 2-naphthylamine in rats. PubMed: Effect propagation in a toxicokinetic/toxicodynamic model explains delayed effects on the growth of unicellular green algae Scenedesmus vacuolatus. PubMed: [Role of allelopathic compositions in the regulation and development of legume-rhizobial symbiosis]. PubMed: Identification of mutagens in freshwater sediments by the Ames-fluctuation assay using nitroreductase and acetyltransferase overproducing test strains. PubMed: Effects of copper sulfate, hydrogen peroxide and N-phenyl-2-naphthylamine on oxidative stress and the expression of genes involved photosynthesis and microcystin disposition in Microcystis aeruginosa. PubMed: Anchoring metabolic changes to phenotypic effects in the chlorophyte Scenedesmus vacuolatus under chemical exposure. PubMed: Effect-directed analysis of sediment-associated algal toxicants at selected hot spots in the river Elbe basin with a special focus on bioaccessibility. PubMed: Phenyl-naphthyl amine effect of new phenothiazine derivatives with high T(g) for hole injection and hole transporting materials. PubMed: Allelochemical stress causes oxidative damage and inhibition of photosynthesis in Chlorella vulgaris. PubMed: Percutaneous absorption of aromatic amines - a contribution for human health risk assessment. PubMed: Julichrome Q6 glucuronide, a monomeric subunit of the julimycin B-I complex from a terrestrial Streptomyces sp. PubMed: Flow cytometry as a tool to study phytotoxic modes of action. PubMed: Dephenylation of the rubber chemical N-phenyl-2-naphthylamine to carcinogenic 2-naphthylamine: a classical problem revisited. PubMed: Effect-directed analysis of key toxicants in European river basins a review. PubMed: On the mode of action of N-phenyl-2-naphthylamine in plants. PubMed: Mechanism study of N-dephenylation mediated through a N-para-hydroxy metabolite. PubMed: A novel alkaloid from Mitrephora maingayi. PubMed: What contributes to the combined effect of a complex mixture? PubMed: Effects of solvent on the fluorescence of 2-anilinonaphthalene. PubMed: Oils and cancer. PubMed: [The carcinogenic and anticarcinogenic properties of neozon D]. PubMed: [PBNA induce malignant transformation in Syrian hamster lung cell culture]. PubMed: NTP Toxicology and Carcinogenesis Studies of N-Phenyl-2-naphthylamine (CAS No. 135-88-6) in F344/N Rats and B6C3F1 Mice (Feed Studies). PubMed: [Mutagenic action of latex polymerization stabilizers in various test systems]. PubMed: Unusual allergic contact dermatitis to aromatic amines. PubMed: [Epidemiology of occupational cancer of the upper respiratory tract in Poland 1971-1985]. PubMed: [Carcinogenic activity of components of polymeric materials]. PubMed: Quantitative analysis of aromatic amines in human urine by gas chromatography-mass spectrometry-selected-ion monitoring. PubMed: Three new contaminants detected in postmortem blood samples. PubMed: Investigation of cancer epidemiology and study of carcinogenic agents in the Shanghai Rubber Industry. PubMed: Carcinogenicity of N-phenyl-1-naphthylamine and N-phenyl-2-naphthylamine in mice. PubMed: [Industrial toxicologic evaluation of vulcanizing vapors with special reference to nitrogen-containing aging-preventive agents]. PubMed: [Analysis of nitrogen containing aging-preventive agents in vulcanizing vapors]. PubMed: Low sensitization rate of naphthyl mix. PubMed: Biological conversion of N-phenyl-2-naphthylamine to 2-naphthylamine in the Sprague-Dawley rat. PubMed: [Carcinogenic risk of Neozone D (N-phenyl-2-naphthylamine)]. PubMed: The chronic effects of magenta, paramagenta and phenyl-beta-naphthylamine in rats after intragastric administration. PubMed: [Method of determining the stabilizer N, N'-diphenyl-p-phenylene-diamine]. PubMed: Hepatic microsomal metabolism and macromolecular binding of the antioxidant, N-phenyl-2-naphthylamine. PubMed: [Mutagenic, embryotropic and blastomogenic action of Neozone D]. PubMed: [Examination of N-phenyl-2-naphthylamine in cooling lubrication fluids used in the metal industry]. PubMed: N-phenyl-2-naphthylamine. PubMed: Dephenylation of N-phenyl-2-naphthylamine in dogs and its possible oncogenic implications. PubMed: [Spectrophotometric determination of isoprene and neozone-D in the water]. PubMed: Booby trap for biochemists: N-phenyl-2-naphthylamine. PubMed: [Cutaneous changes caused by phenyl-beta-naphthylamine].