N-phenyl-2-naphthyl amine
neozone
Identification
| Name | N-phenyl-2-naphthyl amine |
| CAS Number | 135-88-6 |
| EINECS | 205-223-9 |
| FDA UNII | 456KT854AJ |
| Molecular Formula | C16 H13 N |
| Molecular Weight | 219.28661000 |
| MDL Number | MFCD00004052 |
| Nikkaji Number | J3.627G |
| Beilstein | 2211188 |
| XlogP3 | 5.10 (est) |
Regulatory
| FDA Mainterm (IAUFC) | 135-88-6 ; PHENYL-BETA-NAPHTHYLAMINE (FREE OF BETA-NAPHTHYLAMINE) |
Physical Properties
| Appearance | light gray to gray powder (est) |
| Assay | 95.00 to 100.00 |
| Food Chemicals Codex Listed | No |
| Soluble in | water, 6.311 mg/L @ 25 °C (est) |
No sensory data available
Safety Information
| Preferred SDS | View |
| Oral/Parenteral Toxicity | oral-mouse LD50 1450 mg/kg |
| Dermal Toxicity | Not determined |
| Inhalation Toxicity | Not determined |
GHS Classification
['GHS Classification in accordance with 29 CFR 1910 (OSHA HCS)', 'GHS Label elements, including precautionary statements']
Safety in Use
| Category | natural substances and extractives |
| Recommendation for N-phenyl-2-naphthyl amine usage levels up to | not for fragrance use. |
| Recommendation for N-phenyl-2-naphthyl amine flavor usage levels up to | not for flavor use. |
OQEMA
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Potential Uses
Natural Occurrence
Synonyms
2-
anilinonaphthalene
2-
naphthylamine, N-phenyl-
beta-
naphthylphenylamine
neozone
neozone D
phenyl-2-naphthylamine
N-
phenyl-2-naphthylamine
phenyl-beta-naphtilamine
2-
phenylaminonaphthalene
N-
phenylnaphthalen-2-amine
PubMed:
Quantification of N-phenyl-2-naphthylamine by gas chromatography and isotope-dilution mass spectrometry and its percutaneous absorption ex vivo under workplace conditions.
PubMed:
Comparative biotoxicity of N-Phenyl-1-naphthylamine and N-Phenyl-2-naphthylamine on cyanobacteria Microcystis aeruginosa.
PubMed:
Induction of Strong Long-Lived Room-Temperature Phosphorescence of N-Phenyl-2-naphthylamine Molecules by Confinement in a Crystalline Dibromobiphenyl Matrix.
PubMed:
[Secretion of Phenolic Compounds into Root Exudates of Pea Seedlings upon Inoculation with Rhizobium leguminosarum bv. viceae or Pseudomonas siringae pv. Pisi].
PubMed:
Pollution-Induced Community Tolerance To Diagnose Hazardous Chemicals in Multiple Contaminated Aquatic Systems.
PubMed:
A toxicokinetic study of specifically acting and reactive organic chemicals for the prediction of internal effect concentrations in Scenedesmus vacuolatus.
PubMed:
Metabolic dephenylation of the rubber antioxidant N-phenyl-2-naphthylamine to carcinogenic 2-naphthylamine in rats.
PubMed:
Effect propagation in a toxicokinetic/toxicodynamic model explains delayed effects on the growth of unicellular green algae Scenedesmus vacuolatus.
PubMed:
[Role of allelopathic compositions in the regulation and development of legume-rhizobial symbiosis].
PubMed:
Identification of mutagens in freshwater sediments by the Ames-fluctuation assay using nitroreductase and acetyltransferase overproducing test strains.
PubMed:
Effects of copper sulfate, hydrogen peroxide and N-phenyl-2-naphthylamine on oxidative stress and the expression of genes involved photosynthesis and microcystin disposition in Microcystis aeruginosa.
PubMed:
Anchoring metabolic changes to phenotypic effects in the chlorophyte Scenedesmus vacuolatus under chemical exposure.
PubMed:
Effect-directed analysis of sediment-associated algal toxicants at selected hot spots in the river Elbe basin with a special focus on bioaccessibility.
PubMed:
Phenyl-naphthyl amine effect of new phenothiazine derivatives with high T(g) for hole injection and hole transporting materials.
PubMed:
Allelochemical stress causes oxidative damage and inhibition of photosynthesis in Chlorella vulgaris.
PubMed:
Percutaneous absorption of aromatic amines - a contribution for human health risk assessment.
PubMed:
Julichrome Q6 glucuronide, a monomeric subunit of the julimycin B-I complex from a terrestrial Streptomyces sp.
PubMed:
Flow cytometry as a tool to study phytotoxic modes of action.
PubMed:
Dephenylation of the rubber chemical N-phenyl-2-naphthylamine to carcinogenic 2-naphthylamine: a classical problem revisited.
PubMed:
Effect-directed analysis of key toxicants in European river basins a review.
PubMed:
On the mode of action of N-phenyl-2-naphthylamine in plants.
PubMed:
Mechanism study of N-dephenylation mediated through a N-para-hydroxy metabolite.
PubMed:
A novel alkaloid from Mitrephora maingayi.
PubMed:
What contributes to the combined effect of a complex mixture?
PubMed:
Effects of solvent on the fluorescence of 2-anilinonaphthalene.
PubMed:
Oils and cancer.
PubMed:
[The carcinogenic and anticarcinogenic properties of neozon D].
PubMed:
[PBNA induce malignant transformation in Syrian hamster lung cell culture].
PubMed:
NTP Toxicology and Carcinogenesis Studies of N-Phenyl-2-naphthylamine (CAS No. 135-88-6) in F344/N Rats and B6C3F1 Mice (Feed Studies).
PubMed:
[Mutagenic action of latex polymerization stabilizers in various test systems].
PubMed:
Unusual allergic contact dermatitis to aromatic amines.
PubMed:
[Epidemiology of occupational cancer of the upper respiratory tract in Poland 1971-1985].
PubMed:
[Carcinogenic activity of components of polymeric materials].
PubMed:
Quantitative analysis of aromatic amines in human urine by gas chromatography-mass spectrometry-selected-ion monitoring.
PubMed:
Three new contaminants detected in postmortem blood samples.
PubMed:
Investigation of cancer epidemiology and study of carcinogenic agents in the Shanghai Rubber Industry.
PubMed:
Carcinogenicity of N-phenyl-1-naphthylamine and N-phenyl-2-naphthylamine in mice.
PubMed:
[Industrial toxicologic evaluation of vulcanizing vapors with special reference to nitrogen-containing aging-preventive agents].
PubMed:
[Analysis of nitrogen containing aging-preventive agents in vulcanizing vapors].
PubMed:
Low sensitization rate of naphthyl mix.
PubMed:
Biological conversion of N-phenyl-2-naphthylamine to 2-naphthylamine in the Sprague-Dawley rat.
PubMed:
[Carcinogenic risk of Neozone D (N-phenyl-2-naphthylamine)].
PubMed:
The chronic effects of magenta, paramagenta and phenyl-beta-naphthylamine in rats after intragastric administration.
PubMed:
[Method of determining the stabilizer N, N'-diphenyl-p-phenylene-diamine].
PubMed:
Hepatic microsomal metabolism and macromolecular binding of the antioxidant, N-phenyl-2-naphthylamine.
PubMed:
[Mutagenic, embryotropic and blastomogenic action of Neozone D].
PubMed:
[Examination of N-phenyl-2-naphthylamine in cooling lubrication fluids used in the metal industry].
PubMed:
N-phenyl-2-naphthylamine.
PubMed:
Dephenylation of N-phenyl-2-naphthylamine in dogs and its possible oncogenic implications.
PubMed:
[Spectrophotometric determination of isoprene and neozone-D in the water].
PubMed:
Booby trap for biochemists: N-phenyl-2-naphthylamine.
PubMed:
[Cutaneous changes caused by phenyl-beta-naphthylamine].