oxosuccinic acid

oxalacetic acid (8CI)

CAS: 328-42-7 C4 H4 O5 MW: 132.07188000

Identification

Nameoxosuccinic acid
CAS Number328-42-7
EINECS206-329-8
FDA UNII2F399MM81J
Molecular FormulaC4 H4 O5
Molecular Weight132.07188000
MDL NumberMFCD00002592
Nikkaji NumberJ5.675H
Beilstein1705475

Regulatory

Physical Properties

Assay 95.00 to 100.00
Food Chemicals Codex Listed No
Melting Point 161.00 °C. @ 760.00 mm Hg
Boiling Point 341.93 °C. @ 760.00 mm Hg (est)
Flash Point 347.00 °F. TCC ( 174.80 °C. ) (est)
logP (o/w) -1.821 (est)
Soluble in water, 1e+006 mg/L @ 25 °C (est)

Cosmetic Information

CosIngcosmetic data
Cosmetic Usesskin conditioning

No sensory data available

Safety Information

Preferred SDSView
Oral/Parenteral ToxicityNot determined
Dermal ToxicityNot determined
Inhalation ToxicityNot determined

GHS Classification

['GHS Classification in accordance with 29 CFR 1910 (OSHA HCS)', 'GHS Label elements, including precautionary statements']

Safety in Use

Categorycosmetic ingredient for skin conditioning
Recommendation for oxosuccinic acid usage levels up tonot for fragrance use.
Recommendation for oxosuccinic acid flavor usage levels up tonot for flavor use.

BOC Sciences

Best of Chemicals Supplier

Quality supplier of research chemicals and biochemicals including inhibitors, building blocks, GMP Products, impurities and metabolites, APIs for Veterinary, Natural Compounds, ADCs, Stem Cell Molecul...

View All Website 1-631-485-4226 account@bocsci.com

TCI AMERICA

Moving Your Chemistry Forward

We continuously strive to advance our technology.

View All Website 1-800-423-8616 Sales-US@TCIchemicals.com;

Potential Uses

None Found

Natural Occurrence

apple plant barley seed tamarind flower tamarind fruit tamarind leaf tamarind seed

Synonyms

2-oxo butanedioic acid oxo butanedioic acid butanedioic acid, 2-oxo- butanedioic acid, oxo- oxo butanedioicacid 3- carboxy-3-oxopropanoic acid oxa lacetic acid oxa lacetic acid (8CI) oxa laceticacid oxa loethanoic acid 2-oxo succinic acid a-keto succinic acid PubMed: VO2+ complexation by bioligands showing keto-enol tautomerism: a potentiometric, spectroscopic, and computational study. PubMed: Isolation and characterization of an apple cytosolic malate dehydrogenase gene reveal its function in malate synthesis. PubMed: Hepatoprotective activity of leaves of Zanthoxylum armatum DC in CCl4 induced hepatotoxicity in rats. PubMed: [Study of metabonomics on pharmacological action appraisal Rhizoma coptidis in rats]. PubMed: Metabolic discrimination of Catharanthus roseus calli according to their relative locations using (1)H-NMR and principal component analysis. PubMed: Molecular cloning and characterization of a novel lactate dehydrogenase gene from Clonorchis sinensis. PubMed: Synthesis and NMR spectroscopy of nine stereoisomeric 5,7-diacetamido-3,5,7,9-tetradeoxynon-2-ulosonic acids. PubMed: Synthesis and identification in bacterial lipopolysaccharides of 5,7-diacetamido-3,5,7,9-tetradeoxy-D-glycero-D-galacto- and -D-glycero-D-talo-non-2-ulosonic acids. PubMed: Activities of superoxide dismutase and catalase in erythrocytes and transaminases in the plasma of carps (Cyprinus carpio L.) exposed to cadmium. PubMed: Biosynthesis of pseudoisoeugenols in tissue cultures of Pimpinella anisum. Phenylalanine ammonia lyase and cinnamic acid 4-hydroxylase activities. PubMed: Escherichia coli fumarase A catalyzes the isomerization of enol and keto oxalacetic acid. PubMed: High molecular weight protein aggregates formed in the liver of the rat following large doses of paracetamol. PubMed: Hydrolysis of phosphoenolpyruvate catalyzed by phosphoenolpyruvate carboxylase from Zea mays. PubMed: Biosynthesis of Phytosiderophores : In Vitro Biosynthesis of 2'-Deoxymugineic Acid from l-Methionine and Nicotianamine. PubMed: Repression of phenylacetic acid transport system in Penicillium chrysogenum Wis 54-1255 by free amino acids and ammonium salts. PubMed: Studies on the biosynthesis of bialaphos (SF-1293). 8. Purification and characterization of 2-phosphinomethylmalic acid synthase from Streptomyces hygroscopicus SF-1293. PubMed: The phosphoenolpyruvate carboxykinase of Trypanosoma (Schizotrypanum) cruzi epimastigotes: molecular, kinetic, and regulatory properties. PubMed: Selective inactivation of heterokaryons of Candida albicans by anaerobiosis. PubMed: [Effect of oxaloacetic acid on hydrogen-calcium metabolism in mitochondria]. PubMed: Effect of phloridzin on lipid biosynthesis by Cladosporium tenuissimum Cooke. PubMed: Aspartate glucan, glycine glucan, and serine glucan for the removal of cobalt and copper from solutions and brines. PubMed: Malic acid production by an electrochemical reduction system combined with the use of diaphorase and methylviologen. PubMed: Testosterone stimulation of mitochondrial aspartate aminotransferase in organ cultures of rat ventral prostate. PubMed: [Mechanism of auto-oscillations in mitochondria based on modulations of succinate dehydrogenase activity]. PubMed: [Regulation of glyoxylate cycle enzymes in Saccharomycopsis lipolytica. I. Effect of the carbon source on isocitrate lyase and malate synthase activity]. PubMed: Morphological and biochemical studies on liver, kidney and gill of fishes affected by pesticides. PubMed: Inhibition of phosphoenolpyruvate carboxykinase by streptonigrin. PubMed: The vitamin status of Viennese school children aged 11-12 years. PubMed: [Functional characteristics of phosphoenolpyruvate carboxylase in bacteria producing lysine]. PubMed: Localization of adenylate cyclase and 5'-nucleotidase activities in human thyroid follicular cells. PubMed: [Role of protonophore activity of oxalacetic acid in inducing Ca2+ yield from mitochondria]. PubMed: Oxidation of meso-diaminosuccinic acid, a possible natural substrate for D-aspartate oxidase. PubMed: Distribution of glucose incorporated into macromolecular material by treponema pallidum. PubMed: Production of methanol from aromatic acids by Pseudomonas putida. PubMed: Cellular content of the Krebs cycle keto acids in yeasts grown on different nitrogen sources, including hydroxylamine. PubMed: [Energy metabolism disorders in the myocardium due to alcoholic intoxication]. PubMed: Effect of ischaemia on the enzyme activity of the hepatic tissue. PubMed: Enzymatic activity of pig heart mitochondrial malate dehydrogenase monomolecular films by surface exchange technique. PubMed: Regulation of aerobic fermentation in protozoans. VI Comparative biochemistry of pathogenic and nonpathogenic protozoans. PubMed: Two omega-amino acid transaminases from Bacillus cereus. PubMed: Inhibitory effect of fumaric acid and dicarboxylic acids on gastric ulceration in rats. PubMed: [Correlation between the 'active' and 'passive' mechanisms of chlortetracycline penetration in the cells of a sensitive and resistant strains of mycobacteria]. PubMed: [Decarboxylation reaction of oxalacetic acid by metal chelates. III. Metal-peptide (author's transl)]. PubMed: [Decarboxylation reaction of oxalacetic acid by metal chelates. II. Metal-amino acid (author's transl)]. PubMed: Catalysis of decarboxylation of oxalacetic acid by modified poly(ethylenimines). PubMed: [Mechanism of bacterial resistance to tetracyclines and the importance of structural elements of tetracycline molecule for induction of resistance]. PubMed: Photofragmentation of alpha-oxocarboxylic acids in aqueous solution. An EPR study. Formation of semidione radicals by decarboxylative substitution of alpha-oxocarboxylic acids by acyl radicals--II. Oxaloacetic acid (oxosuccinic acid). PubMed: [Canges in nucleoprotein metabolism in the rat brain. III. Effect of a single concentration or of a mixture of oxalacetic acid, alpha-ketoglutarate and pyridoxal-5-phosphate in animals subjected to muscular exercise]. PubMed: [Changes in nucleoprotein metabolism in the rat brain. II. Effect of the administration of a combination of oxalacetic acid, alpha-ketoglutaric acid and pyridoxal-5-phosphate in normal and fatigued animalsA1]. PubMed: [Changes of the alkaline phosphatase, glutamine oxalacetic acid transaminase and lipid fraction, respectively, of the serum and of the liver in rats after local irradiation of the liver with 8000 R]. PubMed: Biotin deficiency in Arthrobactger globiformis: comparative cell ultrastructure and nonreplacement of the vitamin by structurally unrelated compounds. PubMed: Non-enzymic β-decarboxylation of aspartic acid. PubMed: Considerations of oxalacetic acid keto--enol equilibria in various solvents. PubMed: [Multiplication of primary and permanent animal cells in oxalacetic acid media]. PubMed: [Effect of oxalacetic acid, malic acid and pyruvate on the adjustment of abnormal fatty acid metabolism in diabetes mellitus]. PubMed: Carbon dioxide effects on fruits : III. The fixation of C(14)O 2 in lemon in an atmosphere enriched with carbon dioxide. PubMed: [Metalioncatalytic decarboxylation of oxalacetic acid(OAA)]. PubMed: [On the keto-enol-balance and decarboxylation of oxalacetic acid (OAA) ]. PubMed: [Experiments on the synthesis of agaricic acid. 2. On the accumulation of alpha-bromstearic acid ethyl ester on oxalacetic acid diethylester]. PubMed: Enzymatic enolization of oxalacetic acid. PubMed: [Glutamic-oxalacetic acid transaminase activity in cerebrospinal fluid]. PubMed: REACTIONS OF OXALACETIC ACID AND THE FERRIC AND AMMONIUM COMPLEXES OF OXALACETIC ACID. REP NO. 571. PubMed: Glutamic acid-oxalacetic acid transaminase in the spinal fluid in infectious diseases of the central nervous system. PubMed: Daily changes in serum glutamic oxalacetic acid transaminase, with reference to the clinical aspects. PubMed: Non-enzymatic reaction of fluoro-oxalacetic acid with pyridine nucleotides. PubMed: [The determination of alcohol dehydrogenase and glutamic acid oxalacetic acid transaminase activity in the human liver after death]. PubMed: [The diagnostic value of serum leucine aminopeptidase, alkaline phosphatase and glutamine oxalacetic acid transaminase activity. Comparative studies]. PubMed: [Studies on the effect of sonic and ultrasonic fields on biochemical processes. VI. Effect on the level of pyruvic acid, oxalacetic acid, citric acid and alpha-ketoglutaric acid in the blood of guinea pigs]. PubMed: [Biological processes of oxalacetic acid decarboxylation]. PubMed: Growth studies on a tissue culture medium containing oxalacetic acid as a source of CO2. PubMed: Differences in the distribution of glutamic acid-oxalacetic acid transaminase- and aldolase-activity among serum protein fractions in patients with acute myocardial infarct and hepatocellular damage. PubMed: [Glutamic acid--pyruvic acid and glutamic acid-oxalacetic acid transaminase in maternal and embryonal organs, placenta, maternal serum and amniotic fluid of gravid rats in normal and pathological conditions]. PubMed: Serum glutamic oxalacetic acid transaminase activity following hypothermia. PubMed: [Condensation of glyoxylic acid with oxalacetic acid]. PubMed: [Serum glutamic acid oxalacetic acid transaminase and aldolase in acute pancreatitis]. PubMed: [A method for determination of calibration curves for colorimetric studies demonstrated by an example of determination of serum glutamic acid-oxalacetic acid-transaminase with the Havemann electrocolorimeter]. PubMed: Cerebrospinal fluid-glutamic oxalacetic acid transaminase in patients receiving electroconvulsive therapy and in neurologic diseases. PubMed: [Glutamic acid-oxalacetic acid transaminase determinations in infancy and childhood II. Studies in connection with hydrocephalus]. PubMed: [Glutamic-oxalacetic acid transaminase determinations in infancy and childhood. II. Studies on premature and newborn infants]. PubMed: [Glutamic-acid oxalacetic acid transaminase determinations in infancy and childhood. I. Studies in relation to hydrocephalus]. PubMed: [Effect of glyoxylic acid and oxalacetic acid on fumarase]. PubMed: [Glutamic acid-oxalacetic acid transaminase determinations in human liver tissue]. PubMed: [On the influence of prednisone on the activity of the serum glutamic-oxalacetic acid transaminase (SGOT) in acute viral hepatitis]. PubMed: [Diagnostic significance of glutamic acid-oxalacetic acid transaminase determination in serum; technical errors and statistical dispersion of normal values]. PubMed: [On the influence of roentgen total body irradiations on the activity of lactic acid dehydrogenase as well as glutamic acid-oxalacetic acid and glutamic acid-pyruvic acid transaminase in blood serum of rats]. PubMed: Lactic dehydrogenase versus glutamic oxalacetic acid transaminase as a diagnostic test for myocardial infarction. PubMed: [Glutamic acid-oxalacetic acid transaminase in pathological changes of the horny layer of the epidermis]. PubMed: [The behavior of serum glutamic acid-oxalacetic acid transaminase in myopathies and neurogenic muscle atrophies]. PubMed: [Enzymatic determination of oxalacetic acid in blood]. PubMed: The enzymatic formation of oxalacetic acid by nonpyridine nucleotide malic dehydrogenase of Micrococcus lysodeikticus. PubMed: Chemoautotrophic carbon dioxide fixation by extracts of Thiobacillus thiooxidans. I. Formation of oxalacetic acid. PubMed: [Diagnostic significance of the serum glutamic acid-oxalacetic acid-transaminase]. PubMed: [A simple method of determination of serum glutamic acid-oxalacetic acid-transaminase]. PubMed: [Diagnostic value of glutamic oxalacetic acid transaminase]. PubMed: The effect of oxalacetic acid and pyruvic acid on hypoglycemia and ketonemia in pregnant ewes. PubMed: Oxalacetic acid as amino group acceptor in transamination. PubMed: The influence of pH on the enzymatic decarboxylation of oxalacetic acid. PubMed: Interrelationships of oxalacetic and l-malic acids in carbon dioxide fixation. PubMed: Enzymatic synthesis of citrate from pyruvate and oxalacetate. PubMed: Studies on the intracellular composition of livers from rats fed various aminoazo dyes; effects on succinoxidase and oxalacetic acid oxidase. PubMed: Decomposition of oxalacetic acid by metal compounds. PubMed: The effect of cations on the decarboxylation of oxalacetic acid. PubMed: Anaerobic phosphorylation due to a coupled oxidation-reduction between alpha-ketoglutaric acid and oxalacetic acid. PubMed: The assay of animal tissues for respiratory enzymes; oxalacetic acid oxidation and the coupled phosphorylations in isotonic homogenates. PubMed: Phosphorylation of glucose due to a coupled oxidation-reduction between alpha-keto-glutaric acid and oxalacetic acid. PubMed: The action of metmyoglobin, oxygen, and manganese on oxalacetic acid.