sodium phenyl pyruvate

2-oxo-3-phenylpropionic acid sodium salt

CAS: 114-76-1 C9 H7 Na O3 MW: 186.14215928

Identification

Namesodium phenyl pyruvate
IUPACsodium 2-oxo-3-phenylpropanoate
CAS Number114-76-1
EINECS204-053-2
FDA UNII7528CW33WW
Molecular FormulaC9 H7 Na O3
Molecular Weight186.14215928
MDL NumberMFCD00002590
Nikkaji NumberJ193.612C
Beilstein4770978

Regulatory

JECFA Food Flavoring1479 2-oxo-3-phenylpropionic acid sodium salt
FEMA Number3892
FDANo longer provide for the use of these seven synthetic flavoring substances

Physical Properties

Appearance white powder (est)
Assay 95.00 to 100.00
Food Chemicals Codex Listed No
Melting Point 300.00 to 302.00 °C. @ 760.00 mm Hg
Boiling Point 299.10 °C. @ 760.00 mm Hg (est)
Vapor Pressure 0.000546 mmHg @ 25.00 °C. (est)
Flash Point 300.00 °F. TCC ( 148.90 °C. ) (est)
logP (o/w) 0.537 (est)
Soluble in water, 6.522e+004 mg/L @ 25 °C (est)

Organoleptic Properties

Odor Description honey

Safety Information

Preferred SDSView
European informationMost important hazard(s):
Oral/Parenteral ToxicityNot determined
Dermal ToxicityNot determined
Inhalation ToxicityNot determined

GHS Classification

['GHS Classification in accordance with 29 CFR 1910 (OSHA HCS)', 'GHS Label elements, including precautionary statements']

Safety in Use

Categoryflavor enhancers
Recommendation for sodium phenyl pyruvate usage levels up tonot for fragrance use.
baked goods-
beverages(nonalcoholic)0.50000
beverages(alcoholic)-
breakfast cereal1.00000
cheese0.50000
chewing gum1.00000
condiments / relishes-
confectionery froastings1.00000
egg products-
fats / oils-
fish products-
frozen dairy-
fruit ices0.50000
gelatins / puddings0.50000
granulated sugar-
gravies-
hard candy1.00000
imitation dairy-
instant coffee / tea-
jams / jellies-
meat products-
milk products0.50000
nut products-
other grains1.00000
poultry-
processed fruits0.10000
processed vegetables-
reconstituted vegetables-
seasonings / flavors50.00000
snack foods-
soft candy1.00000
soups-
sugar substitutes0.50000
sweet sauces1.00000

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Potential Uses

None Found

Natural Occurrence

not found in nature

Synonyms

benzenepropanoic acid, a-oxo-, sodium salt benzenepropanoic acid, a-oxo-, sodium salt (1:1) phenyl pyruvic acid sodium salt phenyl pyruvic acid sodium salt monohydrate 2-oxo-3- phenylpropionic acid sodium salt phenylpyruvic acid sodium salt phenylpyruvic acid, sodium salt sodium 2-oxidanylidene-3-phenyl-propanoate sodium 2-oxo-3-phenyl propanoate sodium 2-oxo-3-phenyl propionate sodium 2-oxo-3-phenylpropanoate sodium 3-phenyl pyruvate sodium phenylpyruvate sodium phenylpyruvate monohydrate sodiumphenylpyruvate PubMed: Differential resuscitative effect of pyruvate and its analogues on VBNC (viable but non-culturable) Salmonella. PubMed: Study on urinary metabolic profile of phenylketonuria by micellar electrokinetic capillary chromatography with dual electrochemical detection--potential clinical application in fast diagnosis of phenylketonuria. PubMed: Discovery and characterization of D-phenylserine deaminase from Arthrobacter sp. TKS1. PubMed: Structural insight into the inhibition of human kynurenine aminotransferase I/glutamine transaminase K. PubMed: Rapid one-step separation and purification of recombinant phenylalanine dehydrogenase in aqueous two-phase systems. PubMed: Comparative studies on enzyme preparations and role of cell components for (R)-phenylacetylcarbinol production in a two-phase biotransformation. PubMed: Antioxidants inhibit human endothelial cell functions through down-regulation of endothelial nitric oxide synthase activity. PubMed: Strategies for neuroprotection against L-trans-2,4-pyrrolidine dicarboxylate-induced neuronal damage during energy impairment in vitro. PubMed: Purification and characterization of pyruvate kinase from lamprey (Entosphenus japonicus) muscle. PubMed: Some metabotropic glutamate receptor ligands reduce kynurenate synthesis in rats by intracellular inhibition of kynurenine aminotransferase II. PubMed: Anilides of (R)-trifluoro-2-hydroxy-2-methylpropionic acid as inhibitors of pyruvate dehydrogenase kinase. PubMed: [Effects of ultraviolet irradiation of blood and sodium hypochlorite on aromatic amino acid metabolism in phlegmons of the maxillofacial region]. PubMed: Metabolic and K(ATP) channel-independent actions of keto acid initiators of insulin secretion. PubMed: Effects of in vivo sodium azide administration on the immunohistochemical localization of kynurenine aminotransferase in the rat brain. PubMed: Effect of microbial siderophores on matrix metalloproteinase-2 activity. PubMed: Quantitative determination of aromatic amino acids and related compounds in rumen fluid by high-performance liquid chromatography. PubMed: Catalytic properties, molecular composition and sequence alignments of pyruvate: ferredoxin oxidoreductase from the methanogenic archaeon Methanosarcina barkeri (strain Fusaro). PubMed: Alanine reverses the inhibitory effect of phenylalanine and its metabolites on Na+,K(+)-ATPase in synaptic plasma membranes from cerebral cortex of rats. PubMed: Rapid determination of phenylalanine and its related compounds in rumen fluid by high-performance liquid chromatography. PubMed: Stimulation of weak organic acid uptake in rat renal tubules by cadmium and nystatin. PubMed: Age-related changes in kynurenic acid production in rat brain. PubMed: Kynurenine aminotransferase activity in human liver: identity with human hepatic C-S lyase activity and a physiological role for this enzyme. PubMed: Purification and characterization of kynurenine-pyruvate aminotransferase from rat kidney and brain. PubMed: Purification and characterization of the pyruvate-ferredoxin oxidoreductase from Clostridium acetobutylicum. PubMed: Distinct phases of the fluorescence response of the lipophilic probe N-phenyl-1-naphthylamine in intact cells and membrane vesicles of Escherichia coli. PubMed: Purification and characterization of a high molecular weight type 1 phosphoprotein phosphatase from the human erythrocyte. PubMed: Chemoreflexes in rabbits. PubMed: Purification and characterization of yeast L-kynurenine aminotransferase with broad substrate specificity. PubMed: Involvement of D-amino-acid oxidase in D-amino acid utilization in the mouse. PubMed: Inhibition of carnitine palmitoyltransferase 1 by phenylalkyloxiranecarboxylic acid and its influence on lipolysis and glucose metabolism in isolated, perfused hearts of streptozotocin-diabetic rats. PubMed: Transport of alpha-keto analogues of amino acids across blood-brain barrier in rats. PubMed: Effects of phenylalanine and its deaminated metabolites on Na+,K+-ATPase activity in synaptosomes from rat brain. PubMed: Effect of pyruvate decarboxylase activity and of pyruvate concentration on the production of 1-hydroxy-1-phenylpropanone in Saccharomyces carlsbergensis. PubMed: Metabolic effects of L-phenyllactate in perfused kidney, liver, and muscle. PubMed: Tryptophan and hydrogen sulfide reaction from modified trypticase soy agar. PubMed: Characteristics of hepatic serine-pyruvate aminotransferase in different mammalian species. PubMed: Effects of aldosterone on Na+ transport in the toad bladder. I. Glycolysis and lactate production under aerobic conditions. PubMed: Purification and properties of chorismate mutase-prephenate dehydratase and prephenate dehydrogenase from Alcaligenes eutrophus. PubMed: Studies on phenylpyruvic acid. I. Keto-enol tautomerism. PubMed: Purification and properties of avian liver p-hydroxyphenylpyruvate hydroxylase. PubMed: Effects of sodium phenylpyruvate on amino acid formation in brain. PubMed: [STUDY OF TRYPTOPHAN METABOLISM IN MAN. APPLICATION TO 2 CASES OF D'EJ'ERINE-SOTTAS DISEASE]. PubMed: Effects of sodium phenylpyruvate on brain amino acids. PubMed: Effects of L-phenylalanine and sodium phenylpyruvate on the formation of melanin from L-tyrosine in melanoma. PubMed: Effects of l-phenylalanine and sodium phenylpyruvate on the formation of adrenaline from l-tyrosine in adrenal medulla in vitro.