phosphorous acid

trihydroxyphosphine

CAS: 13598-36-2 H3 O3 P MW: 81.99527200

Identification

Namephosphorous acid
IUPACdihydroxy(oxo)phosphanium
CAS Number13598-36-2
EINECS237-066-7
FDA UNII35V6A8JW8E
Molecular FormulaH3 O3 P
Molecular Weight81.99527200
MDL NumberMFCD00137258

Regulatory

Physical Properties

Appearance white or yellow crystalline solid (est)
Assay 95.00 to 100.00
Food Chemicals Codex Listed No
Specific Gravity 1.65100 @ 25.00 °C.
Soluble in water, 1.341e+004 mg/L @ 25 °C (est)

No sensory data available

Safety Information

Oral/Parenteral Toxicityoral-mouse LD50 1700 mg/kg
Dermal ToxicityNot determined
Inhalation ToxicityNot determined

GHS Classification

['GHS Classification in accordance with 29 CFR 1910 (OSHA HCS)', 'GHS Label elements, including precautionary statements']

Safety in Use

Categoryinformation only not used for fragrances or flavors
Recommendation for phosphorous acid usage levels up tonot for fragrance use.
Recommendation for phosphorous acid flavor usage levels up tonot for flavor use.

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Potential Uses

None Found

Natural Occurrence

not found in nature

Synonyms

dihydroxy(oxo)phosphanium dihydroxyphosphine oxide orthophosphorus acid phosphonic acid phosphorus trihydroxide trihydroxyphosphine PubMed: Unmasking the Action of Phosphinous Acid Ligands in Nitrile Hydration Reactions Catalyzed by Arene-Ruthenium(II) Complexes. PubMed: Metal- and Oxidant-Free Synthesis of Quinazolinones from β-Ketoesters with o-Aminobenzamides via Phosphorous Acid-Catalyzed Cyclocondensation and Selective C-C Bond Cleavage. PubMed: L-Argininium phosphite - a new candidate for NLO materials. PubMed: Photocatalytic degradation of acephate in pak choi, Brassica chinensis, with Ce-doped TiO2. PubMed: Differentiating phosphate-dependent and phosphate-independent systemic phosphate-starvation response networks in Arabidopsis thaliana through the application of phosphite. PubMed: Potassium phosphite increases tolerance to UV-B in potato. PubMed: Production of xylitol and tetrahydrofurfuryl alcohol from xylan in napier grass by a hydrothermal process with phosphorus oxoacids followed by aqueous phase hydrogenation. PubMed: Preparation and cytocompatibility evaluation for hydrosoluble phosphorous acid-derivatized cellulose as tissue engineering scaffold material. PubMed: Substitution of gadolinium ethylenediaminetetraacetate with phosphites: towards gadolinium deposit in nephrogenic systemic fibrosis. PubMed: Control of PbSe nanorod aspect ratio by limiting phosphine hydrolysis. PubMed: Proteomics analysis suggests broad functional changes in potato leaves triggered by phosphites and a complex indirect mode of action against Phytophthora infestans. PubMed: From order to disorder and back again: in situ hydrothermal redox reactions of uranium phosphites and phosphates. PubMed: Syntheses, structures, and spectroscopic properties of plutonium and americium phosphites and the redetermination of the ionic radii of Pu(III) and Am(III). PubMed: Rh(I)-catalyzed enantioselective hydrogenation of α-substituted ethenylphosphonic acids. PubMed: Phosphonated cross-linked polyethylenimine for selective removal of uranium ions from aqueous solutions. PubMed: Systematic evolution from uranyl(VI) phosphites to uranium(IV) phosphates. PubMed: Dissecting phosphite-induced priming in Arabidopsis infected with Hyaloperonospora arabidopsidis. PubMed: N-heterocyclic dronic acids: applications and synthesis. PubMed: Nitrosyl induces phosphorous-acid dissociation in ruthenium(II). PubMed: Pharmacist Theodor Salzer (1833-1900) and the discovery of bisphosphonates. PubMed: Characterization of sulfonated poly(ether ether ketone)/silane nanocomposite membrane for high temperature polymer electrolyte membrane fuel cells. PubMed: Reducing the impact of pesticides on biological control in Australian vineyards: pesticide mortality and fecundity effects on an indicator species, the predatory mite Euseius victoriensis (Acari: Phytoseiidae). PubMed: Zeolitic polyoxometalate-based metal-organic frameworks (Z-POMOFs): computational evaluation of hypothetical polymorphs and the successful targeted synthesis of the redox-active Z-POMOF1. PubMed: Enhanced photocatalytic activity for degrading Rhodamine B solution of commercial Degussa P25 TiO2 and its mechanisms. PubMed: Phosphorous acid analogs of novel P2-P4 macrocycles as inhibitors of HCV-NS3 protease. PubMed: Transformation of a layered zinc phosphite to a three-dimensional open-framework structure with intersecting 16- and 12-ring channels. PubMed: Synthesis, reactivity, and kinetics of substitution in W3PdSe4 cuboidal clusters. A reexamination of the kinetics of substitution of the related W3S4 cluster with thiocyanate. PubMed: [Synthesis of acetal and phosphocyclic methriolipids]. PubMed: Identification of a new phytophthora species causing root and runner rot of cranberry in new jersey. PubMed: Phosphorous acid and urea: valuable sources of phosphorus and nitrogen in the hydrothermal synthesis of ammonium-thorium phosphates. PubMed: Controlling the activation of white phosphorus: formation of phosphorous acid and ruthenium-coordinated 1-hydroxytriphosphane by hydrolysis of doubly metalated P4. PubMed: [Study on HPLC fingerprint of processed Radix Angelicae Dahuricae]. PubMed: Mixtures of chiral phosphorous acid diesters and achiral p ligands in the enantio- and diastereoselective hydrogenation of ketimines. PubMed: [Solubilities of ephedrine and d-pseudo-ephedrine from different sizes of ultramicro-particles of the compound traditional Chinese herbs Maxing Shigan decoction]. PubMed: Structural diversity in 4,4'-trimethylenedipyridine-zinc phosphite hybrids: incorporation of neutral guest molecules in hybrid materials. PubMed: Determination of seven compounds in Tang Maikang granule by high-performance liquid chromatography. PubMed: Residue formations of phosphorus hydride polymers and phosphorus oxyacids during phosphine gas fumigations of stored products. PubMed: Stabilization of the tautomers HP(OH)2 and P(OH)3 of hypophosphorous and phosphorous acids as ligands. PubMed: [The simultaneous determination of laetrile, paeoniflorin and paeonol in Jingzhi Guizhi Fuling capsule by HPLC]. PubMed: Phosphorous acid residues in apples after foliar fertilization: results of field trials. PubMed: Highly electrophilic, 16-electron [Ru(P(OMe)(OH)(2))(dppe)(2)](2+) complex turns H(2)(g) into a strong acid and splits a Si-H bond heterolytically. Synthesis and structure of the novel phosphorous acid complex [Ru(P(OH)(3))(dppe)(2)](2+). PubMed: Phosphorylated derivatives that activate or inhibit mammalian adenosine kinase provide insights into the role of pentavalent ions in AK catalysis. PubMed: [Catalytic spectrophotometric determination of trace amounts of copper with the system of ascorbic acid and ammonium molybdate]. PubMed: Synthesis and antiherpetic activity of acyclovir phosphonates. PubMed: [Studies on the synthesis and bioactivity of alpha-alkylaminobenzyl-phosphonic acids]. PubMed: On the Reaction of Phosphorous Acid with Superacids and the Crystal Structure of H(5)O(2)(+)SbF(6)(-) and Me(4)N(+)HPF(5)(-). PubMed: The rates of hydrolysis of thymidyl-3',5'-thymidine-H-phosphonate: the possible role of nucleic acids linked by diesters of phosphorous acid in the origins of life. PubMed: Phosphorous acid and arsenious acid as ligands. PubMed: A phosphonate-induced gene which promotes Penicillium-mediated bioconversion of cis-propenylphosphonic acid to fosfomycin. PubMed: Triester glycerothiophosphates of cholecalciferol (vitamin D3). PubMed: Alkylation reaction of phosphorus oxyacids. PubMed: [The combined action of the components of compound PSB-500 and its hygienic standardization in the water of reservoirs]. PubMed: [Experimental substantiation of maximum allowable concentration of phosphoric acid in the water of reservoirs]. PubMed: Activation of Pseudomonas ochraceae 4-hydroxy-4-methyl-2-oxoglutarate aldolase by inorganic phosphate. PubMed: 31P NMR studies on the effect of phosphite on Phytophthora palmivora. PubMed: [Scanning electron microscopy and microprobe studies of fillings prepared with dentin glue]. PubMed: Studies on the role of tetrazole in the activation of phosphoramidites. PubMed: Triphenyl phosphite neurotoxicity in the hen: inhibition of neurotoxic esterase and of prophylaxis by phenylmethylsulfonyl fluoride. PubMed: Histopathological assessment of triphenyl phosphite neurotoxicity in the hen. PubMed: 131I labeled diphosphonates for the palliative treatment of bone metastases--IV. Syntheses of benzylidenediphosphonates and their organ distribution in rats. PubMed: NTP Toxicology and Carcinogenesis Studies of Dimethyl Hydrogen Phosphite (CAS No. 868-85-9) in F344/N Rats and B6C3F1 Mice (Gavage Studies). PubMed: Nonbactericidal approach to reduce colonization of plaque microflora on teeth in vitro and in vivo. PubMed: [Mutagenic action of 5 prospective pesticides on mouse bone marrow, in a culture of human peripheral blood lymphocytes and on saccharomycete yeasts]. PubMed: Synthesis and separation of diastereomers of deoxynucleoside 5'-O-(1-thio)triphosphates. PubMed: Transformation of some hydroxy amino acids to other amino acids. PubMed: [Addition of phosphorous acid diamides and their phenylogs to double-bound systems].