heliotropic acid
3,4-methylenedioxybenzoic acid
Identification
| Name | heliotropic acid |
| CAS Number | 94-53-1 |
| EINECS | 202-342-8 |
| FDA UNII | QX3V1NO0KH |
| Molecular Formula | C8 H6 O4 |
| Molecular Weight | 166.13262000 |
| MDL Number | MFCD00005830 |
| Nikkaji Number | J4.700G |
| Beilstein | 150206 |
| XlogP3 | 0.40 (est) |
Regulatory
Physical Properties
| Assay | 95.00 to 100.00 |
| Food Chemicals Codex Listed | No |
| Melting Point | 227.00 to 228.00 °C. @ 760.00 mm Hg |
| Boiling Point | 324.59 °C. @ 760.00 mm Hg (est) |
| Flash Point | 283.00 °F. TCC ( 139.60 °C. ) (est) |
| logP (o/w) | 0.810 (est) |
| Soluble in | water, 1424 mg/L @ 25 °C (est) |
| Insoluble in | water |
No sensory data available
Safety Information
| Preferred SDS | View |
| Oral/Parenteral Toxicity | intraperitoneal-mouse LD50 > 800 mg/kg |
| Dermal Toxicity | Not determined |
| Inhalation Toxicity | Not determined |
GHS Classification
['GHS Classification in accordance with 29 CFR 1910 (OSHA HCS)', 'GHS Label elements, including precautionary statements']
Safety in Use
| Category | natural substances and extractives |
| Recommendation for heliotropic acid usage levels up to | not for fragrance use. |
| Recommendation for heliotropic acid flavor usage levels up to | not for flavor use. |
BOC Sciences
Best of Chemicals Supplier
Quality supplier of research chemicals and biochemicals including inhibitors, building blocks, GMP Products, impurities and metabolites, APIs for Veterinary, Natural Compounds, ADCs, Stem Cell Molecul...
Penta International Corporation
Chemistry innovation
At Penta, our products and services help businesses do business better.
Potential Uses
Natural Occurrence
Synonyms
benzo[1,3]dioxole-5-carboxylic acid
benzo[d][1,3]dioxole-5-carboxylic acid
2H-
benzo[d]1,3-dioxolene-5-carboxylic acid
1,3-
benzodioxole-5-carboxylic acid
benzoic acid, 3,4-(methylenedioxy)-
3,4-
dioxymethylenebenzoic acid
3,4-
methylene dioxybenzoic acid
3,4-(
methylenedioxy)benzoic acid
3,4-
methylenedioxybenzoic acid
piperonylic acid
piperonylicacid
protocatechuic acid methylene ether
PubMed:
Antifungal activity of compounds extracted from Cortex Pseudolaricis against Colletotrichum gloeosporioides.
PubMed:
Enhanced lignin monomer production caused by cinnamic Acid and its hydroxylated derivatives inhibits soybean root growth.
PubMed:
Phenolic esters of O-desmethylvenlafaxine with improved oral bioavailability and brain uptake.
PubMed:
Cinnamic acid increases lignin production and inhibits soybean root growth.
PubMed:
Non-cell-autonomous postmortem lignification of tracheary elements in Zinnia elegans.
PubMed:
Production of natural fragrance aromatic acids by coexpression of trans-anethole oxygenase and p-anisaldehyde dehydrogenase genes of Pseudomonas putida JYR-1 in Escherichia coli.
PubMed:
[Study on the bioactive constituents of Piper wallichii].
PubMed:
Exogenous caffeic acid inhibits the growth and enhances the lignification of the roots of soybean (Glycine max).
PubMed:
Accumulation of p-hydroxybenzoic acid in hairy roots of Daucus carota 2: confirming biosynthetic steps through feeding of inhibitors and precursors.
PubMed:
Soybean (Glycine max) root lignification induced by ferulic acid. The possible mode of action.
PubMed:
Metabolites from the Lichen Ochrolechia parella growing under two different heliotropic conditions.
PubMed:
8-Bromo-7-hydroxyquinoline as a photoremovable protecting group for physiological use: mechanism and scope.
PubMed:
Study of cis-cinnamic acid in Arabidopsis thaliana.
PubMed:
Synthesis and evaluation of the antitrypanosomal and antiplasmodial activities of new 4-aminobicyclo[2.2.2]octane derivatives.
PubMed:
Thermodynamic study of sesamol, piperonyl alcohol, piperonylic acid and homopiperonylic acid: a combined experimental and theoretical investigation.
PubMed:
Biotransformations of propenylbenzenes by an Arthrobacter sp. and its t-anethole blocked mutants.
PubMed:
Chemical inactivation of the cinnamate 4-hydroxylase allows for the accumulation of salicylic acid in elicited cells.
PubMed:
Free and conjugated benzoic acid in tobacco plants and cell cultures. Induced accumulation upon elicitation of defense responses and role as salicylic acid precursors.
PubMed:
Piperonylic acid, a selective, mechanism-based inactivator of the trans-cinnamate 4-hydroxylase: A new tool to control the flux of metabolites in the phenylpropanoid pathway
PubMed:
[New data on heliotropic dystrophy of the liver].
PubMed:
Metabolic disposition of piperine in the rat.
PubMed:
The metabolism of some food additives related to piperonal in the rabbit.
PubMed:
Heterocyclic and piperonylic acid esters of 1-methyl-4-piperidinol as analgesics.
PubMed:
Biologically active substances in oak gall extracts. Part 1: Isolation and chemical identification of a substance exerting antihistamine-like activity (KC-18).
PubMed:
Microbial degradation of piperonylic acid.
PubMed:
Microbial degradation of piperonylic acid by Pseudomonas fluorescens.
PubMed:
Piperonylic acid conjugates with alanine, glutamate, glutamine, glycine, and serine in living houseflies.