potassium nitrite

nitrous acid, potassium salt (1:1)

CAS: 7758-09-0 K N O2 MW: 85.10370000

Identification

Namepotassium nitrite
CAS Number7758-09-0
EINECS231-832-4
FDA UNII794654G42L
Molecular FormulaK N O2
Molecular Weight85.10370000
MDL NumberMFCD00011408
Nikkaji NumberJ4.518G

Regulatory

FDA/DG SANTE Petitions, Reviews, NoticesEU SANCO
JECFA Food AdditivePotassium Nitrite
GSFA CodexPotassium nitrite (249)
DG SANTE Food Additivespotassium nitrite
FDA Mainterm (SATF)7758-09-0 ; POTASSIUM NITRITE
FDA RegulationFDA PART 181 -- PRIOR-SANCTIONED FOOD INGREDIENTS

Physical Properties

Appearance white to pale yellow granules (est)
Assay 95.00 to 100.00
Food Chemicals Codex Listed No
Specific Gravity 1.91500 @ 25.00 °C.
Soluble in water, 1e+006 mg/L @ 25 °C (est)
Insoluble in alcohol

No sensory data available

Safety Information

Oral/Parenteral Toxicityoral-rabbit LD50 200 mg/kg
Dermal ToxicityNot determined
Inhalation Toxicityinhalation-mouse LC50 85000 mg/m3

GHS Classification

['GHS Classification in accordance with 29 CFR 1910 (OSHA HCS)', 'GHS Label elements, including precautionary statements', 'SENSE ORGANS AND SPECIAL SENSES: TINNITUS: EAR\nCARDIAC: PULSE RATE INCREASE WITHOUT FALL IN BP\nVASCULAR: BP LOWERING NOT CHARACTERIZED IN AUTONOMIC SECTION']

Safety in Use

Categorycolor fixatives and preservative agents
Recommendation for potassium nitrite usage levels up tonot for fragrance use.
Recommendation for potassium nitrite flavor usage levels up tonot for flavor use.

No supplier data available

Potential Uses

None Found

Natural Occurrence

not found in nature

Synonyms

nitrous acid potassium salt (1:1) nitrous acid, potassium salt nitrous acid, potassium salt (1:1) potassium nitrite (1:1) potassium nitrite [UN1488] [Oxidizer] PubMed: Plant-fungal ecology. Niche engineering demonstrates a latent capacity for fungal-algal mutualism. PubMed: Cu(OTf)2-catalyzed selective arene C-H bond hydroxylation and nitration with KNO2 as an ambident O- and N-nucleophile via a Cu(II)-Cu(III)-Cu(I) mechanism. PubMed: Detection and identification of 2-nitro-morphine and 2-nitro-morphine-6-glucuronide in nitrite adulterated urine specimens containing morphine and its glucuronides. PubMed: Heterotrophic nitrifying and oxygen tolerant denitrifying bacteria from greenwater system of coastal aquaculture. PubMed: Effect of oxidizing adulterants on human urinary steroid profiles. PubMed: 2-Nitro-6-monoacetylmorphine: potential marker for monitoring the presence of 6-monoacetylmorphine in urine adulterated with potassium nitrite. PubMed: Effect of diet composition and mixture of selected food additives on the erythrocytic system and iron metabolism in peripheral blood of male rats. PubMed: Characterization of a diesel-degrading strain isolated from a hydrocarbon-contaminated site. PubMed: Generation of nitric oxide from nitrite by carbonic anhydrase: a possible link between metabolic activity and vasodilation. PubMed: Citrus co-products as technological strategy to reduce residual nitrite content in meat products. PubMed: Photooxidation of halides by chlorophyll at the air-salt water interface. PubMed: Pseudoazurin dramatically enhances the reaction profile of nitrite reduction by Paracoccus pantotrophus cytochrome cd1 and facilitates release of product nitric oxide. PubMed: Beta-MnO2 3D nanostructures: mineralizer-assisted synthesis, characterization, and growth mechanism. PubMed: Electrochemical oxidation of nitrite and the oxidation and reduction of NO2 in the room temperature ionic liquid [C2mim][NTf2]. PubMed: [Effects of potassium salts on direct induction of microtubers in Pinellia ternata]. PubMed: Genotoxicity testing of four food preservatives and their combinations in the Drosophila wing spot test. PubMed: Transcriptional regulation of nir and nor operons of Paracoccus denitrificans. PubMed: Comparison of spot tests with AdultaCheck 6 and Intect 7 urine test strips for detecting the presence of adulterants in urine specimens. PubMed: [Effect of nitrite-anions on Ca2+ transport into the sarcolemma of myometrium]. PubMed: Rapid spot tests for detecting the presence of adulterants in urine specimens submitted for drug testing. PubMed: Potassium nitrite reaction with 11-nor-delta 9-tetrahydrocannabinol-9-carboxylic acid in urine in relation to the drug screening analysis. PubMed: NO-dependent regulation of lectin- and menadione-induced H2O2 production by cells from pleural effusions of lung cancer patients and by immune cells. PubMed: Helicobacter pylori is killed by nitrite under acidic conditions. PubMed: A randomized trial of acidified nitrite cream in the treatment of tinea pedis. PubMed: Effect of nitrite on blood pressure in anaesthetized and free-moving rats. PubMed: Nitrite-induced adrenal effects in rats and the consequences for the no-observed-effect level. PubMed: The nitrosation of hexetidine and hexedine: characterization of the major nitrosamine from common antimicrobial agents. PubMed: Synthesis and evaluation of antimicrobial activity of new 4-nitroso and 4-diazopyrazole derivatives. PubMed: Effect of nitrite ingestion on the bioavailability of folate in the rat. PubMed: Bacterial mutagenicity testing of 49 food ingredients gives very few positive results. PubMed: 4-week oral toxicity study of a combination of eight chemicals in rats: comparison with the toxicity of the individual compounds. PubMed: Evaluation of the oral toxicity of potassium nitrite in a 13-week drinking-water study in rats. PubMed: Free radical scavenging and the expression of potentially lethal damage in X-irradiated repair-deficient Escherichia coli. PubMed: Oxidation reaction of human oxyhemoglobin with nitrite: a reexamination. PubMed: [Growth in weaned piglets and levels of iodothyronines in the blood during the administration of thyroactive substances]. PubMed: Protective action of ascorbic acid against mutagenicity of aminopyrine plus nitrite. PubMed: The role of hydroxyl radical scavengers in preventing DNA strand breaks induced by X irradiation of toluene-treated Escherichia coli. PubMed: [Nitrification in soil columns subjected to continuous flow]. PubMed: Methylation of liver DNA of rat and mouse by N-nitrosodimethylamine formed in vivo from dimethylamine and nitrite. PubMed: Mutagenicity of oxytetracycline. PubMed: Polarographic determination of butorphanol tartrate. PubMed: Synthesis of protein, nucleosides and other organic compounds from cyanamide and potassium nitrite under possible primitive earth conditions. PubMed: Some physiological studies on Penicillium expansum Link. PubMed: Reproduction in the guinea pig as affected by chronic administration of potassium nitrate and potassium nitrite.