potassium nitrite
nitrous acid, potassium salt (1:1)
Identification
| Name | potassium nitrite |
| CAS Number | 7758-09-0 |
| EINECS | 231-832-4 |
| FDA UNII | 794654G42L |
| Molecular Formula | K N O2 |
| Molecular Weight | 85.10370000 |
| MDL Number | MFCD00011408 |
| Nikkaji Number | J4.518G |
Regulatory
| FDA/DG SANTE Petitions, Reviews, Notices | EU SANCO |
| JECFA Food Additive | Potassium Nitrite |
| GSFA Codex | Potassium nitrite (249) |
| DG SANTE Food Additives | potassium nitrite |
| FDA Mainterm (SATF) | 7758-09-0 ; POTASSIUM NITRITE |
| FDA Regulation | FDA PART 181 -- PRIOR-SANCTIONED FOOD INGREDIENTS |
Physical Properties
| Appearance | white to pale yellow granules (est) |
| Assay | 95.00 to 100.00 |
| Food Chemicals Codex Listed | No |
| Specific Gravity | 1.91500 @ 25.00 °C. |
| Soluble in | water, 1e+006 mg/L @ 25 °C (est) |
| Insoluble in | alcohol |
No sensory data available
Safety Information
| Oral/Parenteral Toxicity | oral-rabbit LD50 200 mg/kg |
| Dermal Toxicity | Not determined |
| Inhalation Toxicity | inhalation-mouse LC50 85000 mg/m3 |
GHS Classification
['GHS Classification in accordance with 29 CFR 1910 (OSHA HCS)', 'GHS Label elements, including precautionary statements', 'SENSE ORGANS AND SPECIAL SENSES: TINNITUS: EAR\nCARDIAC: PULSE RATE INCREASE WITHOUT FALL IN BP\nVASCULAR: BP LOWERING NOT CHARACTERIZED IN AUTONOMIC SECTION']
Safety in Use
| Category | color fixatives and preservative agents |
| Recommendation for potassium nitrite usage levels up to | not for fragrance use. |
| Recommendation for potassium nitrite flavor usage levels up to | not for flavor use. |
No supplier data available
Potential Uses
Natural Occurrence
Synonyms
nitrous acid potassium salt (1:1)
nitrous acid, potassium salt
nitrous acid, potassium salt (1:1)
potassium nitrite (1:1)
potassium nitrite [UN1488] [Oxidizer]
PubMed:
Plant-fungal ecology. Niche engineering demonstrates a latent capacity for fungal-algal mutualism.
PubMed:
Cu(OTf)2-catalyzed selective arene C-H bond hydroxylation and nitration with KNO2 as an ambident O- and N-nucleophile via a Cu(II)-Cu(III)-Cu(I) mechanism.
PubMed:
Detection and identification of 2-nitro-morphine and 2-nitro-morphine-6-glucuronide in nitrite adulterated urine specimens containing morphine and its glucuronides.
PubMed:
Heterotrophic nitrifying and oxygen tolerant denitrifying bacteria from greenwater system of coastal aquaculture.
PubMed:
Effect of oxidizing adulterants on human urinary steroid profiles.
PubMed:
2-Nitro-6-monoacetylmorphine: potential marker for monitoring the presence of 6-monoacetylmorphine in urine adulterated with potassium nitrite.
PubMed:
Effect of diet composition and mixture of selected food additives on the erythrocytic system and iron metabolism in peripheral blood of male rats.
PubMed:
Characterization of a diesel-degrading strain isolated from a hydrocarbon-contaminated site.
PubMed:
Generation of nitric oxide from nitrite by carbonic anhydrase: a possible link between metabolic activity and vasodilation.
PubMed:
Citrus co-products as technological strategy to reduce residual nitrite content in meat products.
PubMed:
Photooxidation of halides by chlorophyll at the air-salt water interface.
PubMed:
Pseudoazurin dramatically enhances the reaction profile of nitrite reduction by Paracoccus pantotrophus cytochrome cd1 and facilitates release of product nitric oxide.
PubMed:
Beta-MnO2 3D nanostructures: mineralizer-assisted synthesis, characterization, and growth mechanism.
PubMed:
Electrochemical oxidation of nitrite and the oxidation and reduction of NO2 in the room temperature ionic liquid [C2mim][NTf2].
PubMed:
[Effects of potassium salts on direct induction of microtubers in Pinellia ternata].
PubMed:
Genotoxicity testing of four food preservatives and their combinations in the Drosophila wing spot test.
PubMed:
Transcriptional regulation of nir and nor operons of Paracoccus denitrificans.
PubMed:
Comparison of spot tests with AdultaCheck 6 and Intect 7 urine test strips for detecting the presence of adulterants in urine specimens.
PubMed:
[Effect of nitrite-anions on Ca2+ transport into the sarcolemma of myometrium].
PubMed:
Rapid spot tests for detecting the presence of adulterants in urine specimens submitted for drug testing.
PubMed:
Potassium nitrite reaction with 11-nor-delta 9-tetrahydrocannabinol-9-carboxylic acid in urine in relation to the drug screening analysis.
PubMed:
NO-dependent regulation of lectin- and menadione-induced H2O2 production by cells from pleural effusions of lung cancer patients and by immune cells.
PubMed:
Helicobacter pylori is killed by nitrite under acidic conditions.
PubMed:
A randomized trial of acidified nitrite cream in the treatment of tinea pedis.
PubMed:
Effect of nitrite on blood pressure in anaesthetized and free-moving rats.
PubMed:
Nitrite-induced adrenal effects in rats and the consequences for the no-observed-effect level.
PubMed:
The nitrosation of hexetidine and hexedine: characterization of the major nitrosamine from common antimicrobial agents.
PubMed:
Synthesis and evaluation of antimicrobial activity of new 4-nitroso and 4-diazopyrazole derivatives.
PubMed:
Effect of nitrite ingestion on the bioavailability of folate in the rat.
PubMed:
Bacterial mutagenicity testing of 49 food ingredients gives very few positive results.
PubMed:
4-week oral toxicity study of a combination of eight chemicals in rats: comparison with the toxicity of the individual compounds.
PubMed:
Evaluation of the oral toxicity of potassium nitrite in a 13-week drinking-water study in rats.
PubMed:
Free radical scavenging and the expression of potentially lethal damage in X-irradiated repair-deficient Escherichia coli.
PubMed:
Oxidation reaction of human oxyhemoglobin with nitrite: a reexamination.
PubMed:
[Growth in weaned piglets and levels of iodothyronines in the blood during the administration of thyroactive substances].
PubMed:
Protective action of ascorbic acid against mutagenicity of aminopyrine plus nitrite.
PubMed:
The role of hydroxyl radical scavengers in preventing DNA strand breaks induced by X irradiation of toluene-treated Escherichia coli.
PubMed:
[Nitrification in soil columns subjected to continuous flow].
PubMed:
Methylation of liver DNA of rat and mouse by N-nitrosodimethylamine formed in vivo from dimethylamine and nitrite.
PubMed:
Mutagenicity of oxytetracycline.
PubMed:
Polarographic determination of butorphanol tartrate.
PubMed:
Synthesis of protein, nucleosides and other organic compounds from cyanamide and potassium nitrite under possible primitive earth conditions.
PubMed:
Some physiological studies on Penicillium expansum Link.
PubMed:
Reproduction in the guinea pig as affected by chronic administration of potassium nitrate and potassium nitrite.