precocene I

2H-1-benzopyran, 7-methoxy-2,2-dimethyl-

CAS: 17598-02-6 C12 H14 O2 MW: 190.24198000

Identification

Nameprecocene I
CAS Number17598-02-6
EINECS241-566-0
FDA UNII25HLF91DGR
Molecular FormulaC12 H14 O2
Molecular Weight190.24198000
MDL NumberMFCD00006818
Nikkaji NumberJ4.080K
Beilstein0133917
XlogP33.30 (est)

Regulatory

Physical Properties

Assay 95.00 to 100.00
Food Chemicals Codex Listed No
Specific Gravity 1.05200 @ 25.00 °C.
Refractive Index 1.56000 @ 20.00 °C.
Boiling Point 292.74 °C. @ 760.00 mm Hg (est)
Flash Point > 230.00 °F. TCC ( > 110.00 °C. )
logP (o/w) 3.350
Soluble in water, 67.52 mg/L @ 25 °C (est)

No sensory data available

Safety Information

Preferred SDSView
Oral/Parenteral ToxicityNot determined
Dermal ToxicityNot determined
Inhalation ToxicityNot determined

GHS Classification

['GHS Classification in accordance with 29 CFR 1910 (OSHA HCS)', 'GHS Label elements, including precautionary statements']

Safety in Use

Categorynatural substances and extractives
Recommendation for precocene I usage levels up tonot for fragrance use.
Recommendation for precocene I flavor usage levels up tonot for flavor use.

No supplier data available

Potential Uses

None Found

Natural Occurrence

found in nature

Synonyms

2H-1- benzopyran, 2,2-dimethyl-7-methoxy- 2H-1- benzopyran, 7-methoxy-2,2-dimethyl- demethoxyageratochromene 6- demethoxyageratochromene 2,2- dimethyl-2H-chromen-7-yl methyl ether 2,2- dimethyl-7-methoxy-2H-1-benzopyran 7- methoxy-2,2-dimethyl chromene 7- methoxy-2,2-dimethyl-2H-1-benzopyran 7- methoxy-2,2-dimethyl-2H-chromen 7- methoxy-2,2-dimethyl-2H-chromene 7- methoxy-2,2-dimethyl-3-chromene 7- methoxy-2,2-dimethylchromene PubMed: Ecocatalysis for 2H-chromenes synthesis: an integrated approach for phytomanagement of polluted ecosystems. PubMed: Precocene-I inhibits juvenile hormone biosynthesis, ovarian activation, aggression and alters sterility signal production in bumble bee (Bombus terrestris) workers. PubMed: Potential of essential oils for protection of grains contaminated by aflatoxin produced by Aspergillus flavus. PubMed: Early manipulation of juvenile hormone has sexually dimorphic effects on mature adult behavior in Drosophila melanogaster. PubMed: Effects of CYP inhibitors on precocene I metabolism and toxicity in rat liver slices. PubMed: Volatile oils from the plant and hairy root cultures of Ageratum conyzoides L. PubMed: Schistosomicidal activity of the essential oil of Ageratum conyzoides L. (Asteraceae) against adult Schistosoma mansoni worms. PubMed: Chemical composition and antibacterial activity of essential oils of Lantana camara, Ageratum houstonianum and Eupatorium adenophorum. PubMed: Ageratum conyzoides essential oil as aflatoxin suppressor of Aspergillus flavus. PubMed: New synthetic precocenoids as potential insect control agents. PubMed: Isolation and identification of precocenes and piperitone from essential oils as specific inhibitors of trichothecene production by Fusarium graminearum. PubMed: Synthesis and insect antifeedant activity of precocene derivatives with lactone moiety. PubMed: Photochromic agents as tools for protein structure study: lapachenole is a photoaffinity ligand of cytochrome P450 3A4. PubMed: Toxicological efficacy of some indigenous dill compounds against the flesh fly, Parasarcophaga dux Thomson. PubMed: [Effect of plants synthesizing biologically active substances-precocenes on insects]. PubMed: Synthesis of new heterocycles through a cation-driven tandem ring-enlargement-annulation reaction. PubMed: Analysis of precocenes in the essential oil of Ageratum spp. by reverse-phase high-performance liquid chromatography. PubMed: An ion exchange liquid chromatography/mass spectrometry method for the determination of reduced and oxidized glutathione and glutathione conjugates in hepatocytes. PubMed: Role of juvenile hormone in the synthesis and sequestration of vitellogenins in the red cotton stainer, Dysdercus koenigii (Heteroptera: Pyrrhocoridae). PubMed: [The effect of antihormones on the susceptibility of Anopheles sacharovi Favre. mosquitoes to the causative agent of malaria Plasmodium gallinaceum Brumpt]. PubMed: Cloning of the cDNA encoding Scg-SPRP, an unusual Ser-protease-related protein from vitellogenic female desert locusts (Schistocerca gregaria). PubMed: Cloning of two cDNAs encoding three small serine protease inhibiting peptides from the desert locust Schistocerca gregaria and analysis of tissue-dependent and stage-dependent expression. PubMed: Structural requirements for the direct and cytochrome P450-dependent reaction of cyclic alpha,beta-unsaturated carbonyl compounds with glutathione: a study with coumarin and related compounds. PubMed: Effect of serum-free medium on cytochrome P450-dependent metabolism and toxicity in rat cultured hepatocytes. PubMed: Effects of precocenes on vitellogenesis in the adult female tick, Ornithodoros moubata (Acari: Argasidae). PubMed: Maintenance of monooxygenase activities and detection of cytochrome P-450-mediated cytotoxicity in Mongolian gerbil hepatocyte cultures. PubMed: Effects of proallatotoxins (precocenes) on the development and reproduction of Rhodnius prolixus: some data. PubMed: Precocene I and Other Constituents of the Essential Oil of Platostoma africanum. PubMed: Effects of precocene analogs on the nematode Caenorhabditis remanei (var. Bangaloreiensis). II. Competitions with a juvenile hormone analog (Methoprene). PubMed: Effects of precocene analogs on the nematode Caenorhabditis remanei (var. Bangaloreiensis). I. Structure/activity relations. PubMed: The antiallatal effects on locusts and lethal effects on nematodes of synthetic precocene-1 derivatives differing at the carbon 7 position. PubMed: Structure-activity studies of the hepatocarcinogenicities of alkenylbenzene derivatives related to estragole and safrole on administration to preweanling male C57BL/6J x C3H/HeJ F1 mice. PubMed: Hepatotoxicity of precocene I in rats. Role of metabolic activation in vivo. PubMed: Effects of precocenes on ovarian development of the seed bug, Oxycarenus lavaterae (F.). PubMed: Metabolism and hepatotoxicity of the naturally occurring benzo[b]pyran precocene I. PubMed: The absolute configuration of precocene I dihydrodiols produced by metabolism of precocene I by corpora allata of Locusta migratoria, in vitro. PubMed: [Action of development inhibitors on Aedes aegypti L. mosquitoes and Rhodnius prolixus Stal. bugs. IV. The activity of precocenes]. PubMed: Activity of precocenes on the Chagas's disease vector, Panstrongylus megistus.