chlorophene

4-chloro-a-phenyl-o-cresol

CAS: 120-32-1 C13 H11 Cl O MW: 218.68187000

Identification

Namechlorophene
IUPAC2-benzyl-4-chlorophenol
CAS Number120-32-1
EINECS204-385-8
FDA UNII7560BB0BO3
Molecular FormulaC13 H11 Cl O
Molecular Weight218.68187000
MDL NumberMFCD00020140
Nikkaji NumberJ39.614A
Beilstein1959194
XlogP34.00 (est)

Regulatory

FDA Mainterm (IAUFC)120-32-1 ; ORTHO-BENZYL-PARA-CHLOROPHENOL

Physical Properties

Assay 95.00 to 100.00
Food Chemicals Codex Listed No
Melting Point 48.50 °C. @ 760.00 mm Hg
Boiling Point 339.60 °C. @ 760.00 mm Hg (est)
Flash Point 319.00 °F. TCC ( 159.20 °C. ) (est)
logP (o/w) 4.410 (est)
Soluble in water, 149 mg/L @ 25 °C (exp)

Cosmetic Information

CosIngcosmetic data
Cosmetic Usesantimicrobial agents

No sensory data available

Safety Information

Preferred SDSView
Oral/Parenteral Toxicityoral-guinea pig LDLo 3000 mg/kg
Dermal Toxicitysubcutaneous-mouse LD50 350 mg/kg
Inhalation Toxicityinhalation-rat LC > 13200 mg/m3/6

GHS Classification

['GHS Classification in accordance with 29 CFR 1910 (OSHA HCS)', 'GHS Label elements, including precautionary statements']

Safety in Use

Categoryantimicrobial preservatives
Recommendation for chlorophene usage levels up tonot for fragrance use.
Recommendation for chlorophene flavor usage levels up tonot for flavor use.

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Potential Uses

preservatives

Natural Occurrence

not found in nature

Synonyms

2- benzyl-4-chlorophenol benzyl-p-chlorophenol o- benzyl-p-chlorophenol omega- benzyl-para-chlorophenol 4- chloranyl-2-(phenylmethyl)phenol 4- chloro-2-(phenylmethyl)phenol 4- chloro-2-benzyl phenol 4- chloro-2-benzylphenol 5- chloro-2-hydroxydiphenylmethane 4- chloro-a-phenyl-o-cresol 4- chloro-a-phenyl-ortho-cresol o- cresol, 4-chloro-a-phenyl- phenol, 4-chloro-2- (phenylmethyl)- phenol, 4-chloro-2-(phenylmethyl)- preventol B santophen PubMed: Removal of pharmaceuticals and personal care products during water recycling: microbial community structure and effects of substrate concentration. PubMed: Photolysis of model emerging contaminants in ultra-pure water: kinetics, by-products formation and degradation pathways. PubMed: Modeling the photodegradation of emerging contaminants in waters by UV radiation and UV/H2O2 system. PubMed: Effect directed analysis and mixture effects of estrogenic compounds in a sediment of the river Elbe. PubMed: Biological removal of pharmaceuticals and personal care products during laboratory soil aquifer treatment simulation with different primary substrate concentrations. PubMed: Determination of pharmaceuticals and antiseptics in water by solid-phase extraction and gas chromatography/mass spectrometry: analysis via pentafluorobenzylation and stable isotope dilution. PubMed: Impact of interactions between metal oxides to oxidative reactivity of manganese dioxide. PubMed: Bioassay-directed identification of novel antiandrogenic compounds in bile of fish exposed to wastewater effluents. PubMed: Sorption of biocides, triazine and phenylurea herbicides, and UV-filters onto secondary sludge. PubMed: Biogenic metals for the oxidative and reductive removal of pharmaceuticals, biocides and iodinated contrast media in a polishing membrane bioreactor. PubMed: Chlorophene degradation by combined ultraviolet irradiation and ozonation. PubMed: Evaluation of various liquid chromatography-quadrupole-linear ion trap-mass spectrometry operation modes applied to the analysis of organic pollutants in wastewaters. PubMed: Safety assessment of dichlorophene and chlorophene. PubMed: Oxidative transformation of triclosan and chlorophene by manganese oxides. PubMed: NTP Toxicology and Carcinogenesis Studies of o-Benzyl-p-Chlorophenol (CAS No. 120-32-1) in F344/N Rats and B6C3F1 Mice (Gavage Studies). PubMed: [Effect of chlorophene on aqueous organisms and chemical characteristics of changes in aqueous medium caused by this substance]. PubMed: [Vitamin C in the organism and its relation to air pollution by wastes from synthetic chlorophene rubber plants].