salicyl amide

benzamide, 2-hydroxy-

CAS: 65-45-2 C7 H7 N O2 MW: 137.13819000

Identification

Namesalicyl amide
IUPAC2-hydroxybenzamide
CAS Number65-45-2
EINECS200-609-3
FDA UNIIEM8BM710ZC
Molecular FormulaC7 H7 N O2
Molecular Weight137.13819000
MDL NumberMFCD00007978
Nikkaji NumberJ1.408G
Beilstein0742439
XlogP31.30 (est)

Regulatory

FDA/DG SANTE Petitions, Reviews, NoticesFCN 46

Physical Properties

Appearance white or slightly pink crystals (est)
Assay 95.00 to 100.00
Food Chemicals Codex Listed No
Melting Point 142.00 °C. @ 760.00 mm Hg
Boiling Point 181.50 °C. @ 760.00 mm Hg
Flash Point 295.00 °F. TCC ( 146.30 °C. ) (est)
logP (o/w) 1.280
Soluble in water, 2060 mg/L @ 25 °C (exp)

Cosmetic Information

CosIngcosmetic data
Cosmetic Useskeratolytics

No sensory data available

Safety Information

Preferred SDSView
Oral/Parenteral Toxicityintraperitoneal-cat LDLo 1000 mg/kg
Dermal Toxicitysubcutaneous-mouse LD50 300 mg/kg
Inhalation ToxicityNot determined

GHS Classification

['GHS Classification in accordance with 29 CFR 1910 (OSHA HCS)', 'GHS Label elements, including precautionary statements', 'BEHAVIORAL: TREMOR\nBEHAVIORAL: SOMNOLENCE (GENERAL DEPRESSED ACTIVITY)\nBEHAVIORAL: ALTERED SLEEP TIME (INCLUDING CHANGE IN RIGHTING REFLEX)', 'LUNGS, THORAX, OR RESPIRATION: RESPIRATORY DEPRESSION\nBEHAVIORAL: SOMNOLENCE (GENERAL DEPRESSED ACTIVITY)\nBEHAVIORAL: ALTERED SLEEP TIME (INCLUDING CHANGE IN RIGHTING REFLEX)']

Safety in Use

Categorycosmetic agents
Recommendation for salicyl amide usage levels up tonot for fragrance use.
Recommendation for salicyl amide flavor usage levels up tonot for flavor use.

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Potential Uses

None Found

Natural Occurrence

not found in nature

Synonyms

acket afko-sal algamon algiamida algiamide allevin amid-sal amidosal anamid andasol benesal benzamide, 2-hydroxy- benzamide, o-hydroxy- benzoic acid, 2-hydroxy-, amide 2- carbamoylphenol 2- carboxamidophenol cdial cetamide cymidon dolomide dropsprin eggosalil flarpirina 2- hydroxy-benzamide 2- hydroxybenzamide o- hydroxybenzamide ortho- hydroxybenzamide 2- hydroxybenzoicacidamide liquiprin morsarinas novecyl oramid panithal raspberin rasperin salamide saliamid saliamin salicim salicylamide salicylic acid amide salipur salizell salrin salymid samid serramida urtosal PubMed: Effects of Sho-saiko-to extract and its components, Baicalin, baicalein, glycyrrhizin and glycyrrhetic acid, on pharmacokinetic behavior of salicylamide in carbon tetrachloride intoxicated rats. PubMed: In vitro efficacy of nitro- and bromo-thiazolyl-salicylamide compounds (thiazolides) against Besnoitia besnoiti infection in Vero cells. PubMed: Identification of metoclopramide metabolites in the urine of cattle by gas chromatography-mass spectrometry and high-performance liquid chromatography-photodiode array detection. PubMed: Glucuronidation of morphine and six beta 2-sympathomimetics in isolated rat intestinal epithelial cells. PubMed: Induction of tachyzoite egress from cells infected with the protozoan Neospora caninum by nitro- and bromo-thiazolides, a class of broad-spectrum anti-parasitic drugs. PubMed: Inhibitory effects of lipophilic acids and related compounds on bacteria and mammalian cells.