sesamol

benzo[1,3]dioxol-5-ol 2H- benzo[d]1,3-dioxolen-5-ol 1,3- benzodioxol-5-ol 2H-1,3- benzodioxol-5-ol 5- hydroxy-1,3-benzodioxole 3,4- methylendioxyphenol 3,4-( methylene dioxy) phenol 3,4- methylene dioxyphenol methylene ether of oxyhydroquinone 3,4-( methylenedioxy)phenol 3,4- methylenedioxyphenol phenol, 3,4-(methylenedioxy)- sesamol PubMed: Anti-Atherosclerotic and Anti-Inflammatory Actions of Sesame Oil. PubMed: The relationship of antioxidant components and antioxidant activity of Sesame seed oil. PubMed: Neuroprotective potential of sesamol and its loaded solid lipid nanoparticles in ICV-STZ-induced cognitive deficits: Behavioral and biochemical evidence. PubMed: Hepatoprotective effects of sesamol loaded solid lipid nanoparticles in carbon tetrachloride induced sub-chronic hepatotoxicity in rats. PubMed: N,N'-Dioxide-Scandium(III)-Catalyzed Asymmetric Aza-Friedel-Crafts Reaction of Sesamol with Aldimines. PubMed: Enhancing antioxidant activity of sesamol at frying temperature by addition of additives through reducing volatility. PubMed: Sesamol-loaded solid lipid nanoparticles for treatment of skin cancer. PubMed: Sesamol and sesame (Sesamum indicum) oil enhance macrophage cholesterol efflux via up-regulation of PPARγ1 and LXRα transcriptional activity in a MAPK-dependent manner. PubMed: Antioxidant, antimelanogenic, and skin-protective effect of sesamol. PubMed: The ameliorative effects of sesamol against seizures, cognitive impairment and oxidative stress in the experimental model of epilepsy. PubMed: Crocin prevents sesamol-induced oxidative stress and apoptosis in human platelets. PubMed: Sesamol suppresses cyclooxygenase-2 transcriptional activity in colon cancer cells and modifies intestinal polyp development in Apc (Min/+) mice. PubMed: Investigation of sesamol on myeloperoxidase and colon morphology in acetic acid-induced inflammatory bowel disorder in albino rats. PubMed: Organocatalytic asymmetric Friedel-Crafts reaction of sesamol with isatins: access to biologically relevant 3-aryl-3-hydroxy-2-oxindoles. PubMed: Sesame oil attenuates nutritional fibrosing steatohepatitis by modulating matrix metalloproteinases-2, 9 and PPAR-γ. PubMed: Sesamol ameliorates cyclophosphamide-induced hepatotoxicity by modulating oxidative stress and inflammatory mediators. PubMed: Plants and phytochemicals for Huntington's disease. PubMed: Application of FTIR microspectroscopy for characterization of biomolecular changes in human melanoma cells treated by sesamol and kojic acid. PubMed: Antioxidant, lipid lowering, and membrane stabilization effect of sesamol against doxorubicin-induced cardiomyopathy in experimental rats. PubMed: Sesamol and naringenin reverse the effect of rotenone-induced PD rat model. PubMed: Protective effect of 3,4-methylenedioxyphenol (sesamol) on stress-related mucosal disease in rats. PubMed: Modulatory effects of sesamol in dinitrochlorobenzene-induced inflammatory bowel disorder in albino rats. PubMed: Lignans of sesame: purification methods, biological activities and biosynthesis--a review. PubMed: Sesamol induces apoptosis in human platelets via reactive oxygen species-mediated mitochondrial damage. PubMed: The interaction of sesamol with DNA and cytotoxicity, apoptosis, and localization in HepG2 cells. PubMed: Beneficial effect of sesame oil on heavy metal toxicity. PubMed: Sesamol prevents doxorubicin-induced oxidative damage and toxicity on H9c2 cardiomyoblasts. PubMed: Implication of NGF and endocannabinoid signaling in the mechanism of action of sesamol: a multi-target natural compound with therapeutic potential. PubMed: DPPH assay of vegetable oils and model antioxidants in protic and aprotic solvents. PubMed: Modulatory effect of sesamol on DOCA-salt-induced oxidative stress in uninephrectomized hypertensive rats. PubMed: Evaluation of sesamol and buspirone in stress induced anxiety in mice. PubMed: Sesamol treatment reduces plasma cholesterol and triacylglycerol levels in mouse models of acute and chronic hyperlipidemia. PubMed: Synthesis and characterization of polymerizable one-component photoinitiator based on sesamol. PubMed: Determination of the degree of oxidation in highly-oxidised lipids using profile changes of fatty acids. PubMed: The role of cyclooxygenase-derived oxidative stress in surgically induced lymphedema in a mouse tail model. PubMed: Attenuation of adjuvant-induced arthritis by dietary sesamol via modulation of inflammatory mediators, extracellular matrix degrading enzymes and antioxidant status. PubMed: Cell-based screening identifies paroxetine as an inhibitor of diabetic endothelial dysfunction. PubMed: DNA interaction studies of sesamol (3,4-methylenedioxyphenol) food additive. PubMed: Synthesis and photopolymerization kinetics of benzophenone sesamol one-component photoinitiator. PubMed: Effect of sesamol on the pathophysiological changes induced by surgical menopause in rodents. PubMed: Efficacy of sesamol on plasma and tissue lipids in isoproterenol-induced cardiotoxicity in Wistar rats. PubMed: Polyalkoxy substituted 4H-chromenes: synthesis by domino reaction and anticancer activity. PubMed: Prophylactic sesame oil attenuates sinusoidal obstruction syndrome by inhibiting matrix metalloproteinase-9 and oxidative stress. PubMed: Direct chemical method for preparing 2,3-epoxyamides using sodium chlorite. PubMed: Comparison of the simple cyclic voltammetry (CV) and DPPH assays for the determination of antioxidant capacity of active principles. PubMed: Therapeutic oral sesame oil is ineffectual against monocrotaline-induced sinusoidal obstruction syndrome in rats. PubMed: Sesamol alleviates diet-induced cardiometabolic syndrome in rats via up-regulating PPARγ, PPARα and e-NOS. PubMed: Patterns of carbohydrate and fatty acid changes under nitrogen starvation in the microalgae Haematococcus pluvialis and Nannochloropsis sp. PubMed: A novel role of sesamol in inhibiting NF-κB-mediated signaling in platelet activation. PubMed: Sesamol attenuates oxidative stress-mediated experimental acute pancreatitis in rats. PubMed: Selective recognition of sesamol using molecularly imprinted polymers containing magnetic wollastonite. PubMed: Delivery of sesamol-loaded solid lipid nanoparticles to the brain for menopause-related emotional and cognitive central nervous system derangements. PubMed: Physicochemical insights on the free radical scavenging activity of sesamol: importance of the acid/base equilibrium. PubMed: Sesamol as a potential radioprotective agent: in vitro studies. PubMed: Effects of sesamol on apoptosis and steroidogenesis in MA-10 mouse Leydig tumor cells. PubMed: Therapeutic sesamol attenuates monocrotaline-induced sinusoidal obstruction syndrome in rats by inhibiting matrix metalloproteinase-9. PubMed: Experimental antithrombotic effects of sesame seed whole grains and extracts. PubMed: Sesamol attenuates isoproterenol-induced acute myocardial infarction via inhibition of matrix metalloproteinase-2 and -9 expression in rats. PubMed: Modulation of nitrergic pathway by sesamol prevents cognitive deficits and associated biochemical alterations in intracerebroventricular streptozotocin administered rats. PubMed: Studies on chemical and sensory parameters of coconut oil and its olein blends with sesame oil and palmolein during wheat flour-based product frying. PubMed: Chondroprotective role of sesamol by inhibiting MMPs expression via retaining NF-κB signaling in activated SW1353 cells. PubMed: Identification of methanol-soluble compounds in sesame and evaluation of antioxidant potential of its lignans. PubMed: Inhibitory activity of natural occurring antioxidants on Thiyl radical-induced trans-arachidonic acid formation. PubMed: Anti-hepatotoxic effects of 3,4-methylenedioxyphenol and N-acetylcysteine in acutely acetaminophen-overdosed mice. PubMed: Comments on Vennila and Pugalendi. Vennila L, Pugalendi KV. Protective effect of sesamol against myocardial infarction caused by isoproterenol in Wistar rats. Redox Rep 2010; 15: 36-42. PubMed: Protection of cellular DNA and membrane from γ-radiation-induced damages and enhancement in DNA repair by sesamol. PubMed: A modified sesamol derivative inhibits progression of atherosclerosis. PubMed: Interaction of sesamol (3,4-methylenedioxyphenol) with tyrosinase and its effect on melanin synthesis. PubMed: Estrogenic activities of sesame lignans and their metabolites on human breast cancer cells. PubMed: Neuropsychopharmacological effect of sesamol in unpredictable chronic mild stress model of depression: behavioral and biochemical evidences. PubMed: Electrostatic spraying of antioxidants on the oxidative quality of ground beef. PubMed: Normal and delayed wound healing is improved by sesamol, an active constituent of Sesamum indicum (L.) in albino rats. PubMed: Identification of cytotoxic dimers in oxidation product from sesamol, a potent antioxidant of sesame oil. PubMed: Sesamol inhibits UVB-induced ROS generation and subsequent oxidative damage in cultured human skin dermal fibroblasts. PubMed: Apoptosis-inducing action of two products from oxidation of sesamol, an antioxidative constituent of sesame oil: a possible cytotoxicity of oxidized antioxidant. PubMed: Comparing antioxidant effectiveness of natural and synthetic free radical scavengers in thermally-oxidized lard using DPPH method. PubMed: Sesamol suppresses neuro-inflammatory cascade in experimental model of diabetic neuropathy. PubMed: The effect of lutein, sesamol, ellagic acid and olive leaf extract on lipid oxidation and oxymyoglobin oxidation in bovine and porcine muscle model systems. PubMed: Protective effect of sesamol on the pulmonary inflammatory response and lung injury in endotoxemic rats. PubMed: Evaluation of the effects of selected phytochemicals on quality indices and sensorial properties of raw and cooked pork stored in different packaging systems. PubMed: Effect of lutein, sesamol, ellagic acid and olive leaf extract on the quality and shelf-life stability of packaged raw minced beef patties. PubMed: Sesamin attenuates intercellular cell adhesion molecule-1 expression in vitro in TNF-alpha-treated human aortic endothelial cells and in vivo in apolipoprotein-E-deficient mice. PubMed: Protective effect of sesamol against myocardial infarction caused by isoproterenol in Wistar rats. PubMed: Influence of chemical structures of benzodioxole-based coinitiators on the properties of the unfilled dental resin. PubMed: Low-cost fluorimetric determination of radicals based on fluorogenic dimerization of the natural phenol sesamol. PubMed: Protective effect of sesamol against 3-nitropropionic acid-induced cognitive dysfunction and altered glutathione redox balance in rats. PubMed: Studies on natural p-terphenyls: total syntheses of vialinin A and terrestrin B. PubMed: Potent antiplatelet activity of sesamol in an in vitro and in vivo model: pivotal roles of cyclic AMP and p38 mitogen-activated protein kinase. PubMed: Sesamol down-regulates the lipopolysaccharide-induced inflammatory response by inhibiting nuclear factor-kappa B activation. PubMed: Development of a novel fluorometric assay for nitric oxide utilizing sesamol and its application to analysis of nitric oxide-releasing drugs. PubMed: Expeditious synthesis of vialinin B, an extremely potent inhibitor of TNF-alpha production. PubMed: Sulfamic acid catalyzed solvent-free synthesis of 10-aryl-7,7-dimethyl-6,7,8,10-tetrahydro-9H-[1,3]-dioxolo [4,5- b]xanthen-9-ones and 12-aryl-9,9-dimethyl-8,9,10,12-tetrahydro-11H-benzo[a]xanthen-11-ones. PubMed: A new cross-coupling-based synthesis of carpanone. PubMed: Fat content influences the color, lipid oxidation, and volatiles of irradiated ground beef. PubMed: Antioxidant potential of sesamol and its role on radiation-induced DNA damage in whole-body irradiated Swiss albino mice. PubMed: The non-peptide chemical 3,4-methylenedioxyphenol blocked lipopolysaccharide (LPS) from binding to LPS-binding protein and inhibited pro-inflammatory cytokines. PubMed: Sesamol: an efficient antioxidant with potential therapeutic benefits. PubMed: Storage stability of sunflower oil with added natural antioxidant concentrate from sesame seed oil. PubMed: Improving the stability and antioxidant properties of sesame oil: water-soluble spray-dried emulsions from new transesterified phenolic derivatives. PubMed: Attenuation of renoinflammatory cascade in experimental model of diabetic nephropathy by sesamol. PubMed: Administration of sesamol improved blood-brain barrier function in streptozotocin-induced diabetic rats. PubMed: Sesamol attenuate 3-nitropropionic acid-induced Huntington-like behavioral, biochemical, and cellular alterations in rats. PubMed: Effect of infrared heating on the formation of sesamol and quality of defatted flours from Sesamum indicum L. PubMed: Cytometric analysis of cytotoxicity of polyphenols and related phenolics to rat thymocytes: potent cytotoxicity of resveratrol to normal cells. PubMed: A previously uncultured, paper mill Propionibacterium is able to degrade O-aryl alkyl ethers and various aromatic hydrocarbons. PubMed: Effects of a diet rich in sesame ( Sesamum indicum) pericarp on the expression of oestrogen receptor alpha and oestrogen receptor beta in rat prostate and uterus. PubMed: Renoprotective effects of sesamol in ferric nitrilotriacetate-induced oxidative renal injury in rats. PubMed: Effect of antioxidant application methods on the color, lipid oxidation, and volatiles of irradiated ground beef. PubMed: Elimination and metabolism of sesamol, a bioactive compound in sesame oil, in rats. PubMed: Glycosylation of sesamol by cultured plant cells. PubMed: Effects of germination on chemical composition and functional properties of sesame (Sesamum indicum L.) seeds. PubMed: Effects of aging time and natural antioxidants on the color, lipid oxidation and volatiles of irradiated ground beef. PubMed: The protective effect of sesamol against mitochondrial oxidative stress and hepatic injury in acetaminophen-overdosed rats. PubMed: Metabolic transformation of sesamol and ex vivo effect on 2,2'-azo-bis(2-amidinopropane)dihydrochloride-induced hemolysis. PubMed: Bioavailability and tissue distribution of sesamol in rat. PubMed: The prophylactic protective effect of sesamol against ferric-nitrilotriacetate-induced acute renal injury in mice. PubMed: Evaluation of coumarin derivatives as anti-fungal agents against soil-borne fungal pathogens. PubMed: Sesamol attenuates diclofenac-induced acute gastric mucosal injury via its cyclooxygenase-independent antioxidative effect in rats. PubMed: Effect of sesamol on diabetes-associated cognitive decline in rats. PubMed: First total synthesis of vialinin A, a novel and extremely potent inhibitor of TNF-alpha production. PubMed: The effect of sesamol on systemic oxidative stress and hepatic dysfunction in acutely iron-intoxicated mice. PubMed: Practical and convenient synthesis of coumarins from phenols and propiolic acid esters. PubMed: Scavenging effects of phenolic compounds on reactive oxygen species. PubMed: Synergistic antimicrobial activities of phytoestrogens in crude extracts of two sesame species against some common pathogenic microorganisms. PubMed: Effect of sesamol on radiation-induced cytotoxicity in Swiss albino mice. PubMed: Characteristics of structured lipid prepared by lipase-catalyzed acidolysis of roasted sesame oil and caprylic acid in a bench-scale continuous packed bed reactor. PubMed: Sesamol delays mortality and attenuates hepatic injury after cecal ligation and puncture in rats: role of oxidative stress. PubMed: Effects of methyl parathion on Chasmagnathus granulatus hepatopancreas: protective role of sesamol. PubMed: Attenuation of endotoxin-induced oxidative stress and multiple organ injury by 3,4-Methylenedioxyphenol in rats. PubMed: Development and evaluation of sesamol as an antiaging agent. PubMed: Sesamol induces nitric oxide release from human umbilical vein endothelial cells. PubMed: Protective effect of 1,2,4-benzenetriol on LPS-induced NO production by BV2 microglial cells. PubMed: Synthesis and HIV-1 integrase inhibitory activities of caffeic acid dimers derived from Salvia officinalis. PubMed: Photoprotective effect of sesamol on UVB-radiation induced oxidative stress in human blood lymphocytes in vitro. PubMed: Improved malonaldehyde assay using headspace solid-phase microextraction and its application to the measurement of the antioxidant activity of phytochemicals. PubMed: Free radical reactions and antioxidant activities of sesamol: pulse radiolytic and biochemical studies. PubMed: Radioprotective effect of sesamol on gamma-radiation induced DNA damage, lipid peroxidation and antioxidants levels in cultured human lymphocytes. PubMed: Sesamol regulates plasminogen activator gene expression in cultured endothelial cells: a potential effect on the fibrinolytic system. PubMed: Sesame lignans enhance antioxidant activity of vitamin E in lipid peroxidation systems. PubMed: Comprehensive study on vitamin C equivalent antioxidant capacity (VCEAC) of various polyphenolics in scavenging a free radical and its structural relationship. PubMed: Inhibitory actions of several natural products on proliferation of rat vascular smooth muscle cells induced by Hsp60 from Chlamydia pneumoniae J138. PubMed: The sesame seed oil constituent, sesamol, induces growth arrest and apoptosis of cancer and cardiovascular cells. PubMed: Thermodynamic study of sesamol, piperonyl alcohol, piperonylic acid and homopiperonylic acid: a combined experimental and theoretical investigation. PubMed: Free radical scavenging behavior of antioxidant compounds of sesame (sesamum indicum L.) in DPPH(*) system. PubMed: Far-infrared radiation increases the antioxidant properties of rice hull extract in cooked turkey meat. PubMed: Use of double packaging and antioxidant combinations to improve color, lipid oxidation, and volatiles of irradiated raw and cooked turkey breast patties. PubMed: Antiphoto-oxidative activity of sesamol in methylene blue- and chlorophyll-sensitized photo-oxidation of oil. PubMed: Action of pyrethrum-based formulations against grain weevils. PubMed: Use of antioxidants to reduce lipid oxidation and off-odor volatiles of irradiated pork homogenates and patties. PubMed: Effect of antioxidants on the quality of irradiated sausages prepared with turkey thigh meat. PubMed: Chemopreventive effect of resveratrol, sesamol, sesame oil and sunflower oil in the Epstein-Barr virus early antigen activation assay and the mouse skin two-stage carcinogenesis. PubMed: Palladium-catalyzed intramolecular C-O bond formation. PubMed: Cytotoxicity effects of di- and tri-hydroxybenzaldehydes as a chemopreventive potential agent on tumor cells. PubMed: Increased survival after cecal ligation and puncture in mice consuming diets enriched with sesame seed oil. PubMed: Field assessment of plant derivative compounds for managing fungal soybean diseases. PubMed: Sesamol exhibits antimutagenic activity against oxygen species mediated mutagenicity. PubMed: Decreased production of interleukin-6 and prostaglandin E2 associated with inhibition of delta-5 desaturation of omega6 fatty acids in mice fed safflower oil diets supplemented with sesamol. PubMed: Increased band 3 protein aggregation and anti-band 3 binding of erythrocyte membranes on treatment with sesamol. PubMed: Synthesis, binding affinity and selectivity of new beta 1- and beta 2-adrenoceptor blockers. PubMed: Medium-term bioassays for carcinogenicity of chemical mixtures. PubMed: Food constituents attenuate monoamine oxidase activity and peroxide levels in C6 astrocyte cells. PubMed: In vitro attenuation of nitric oxide production in C6 astrocyte cell culture by various dietary compounds. PubMed: Sesamolin inhibits lipid peroxidation in rat liver and kidney. PubMed: Carcinogenicity of antioxidants BHA, caffeic acid, sesamol, 4-methoxyphenol and catechol at low doses, either alone or in combination, and modulation of their effects in a rat medium-term multi-organ carcinogenesis model. PubMed: The prevention of ferric nitrilotriacetate-induced nephro- and hepatotoxicity by methylenedioxybenzene antioxidants. PubMed: Malic enzyme: a lipogenic enzyme in fungi. PubMed: Comparative evaluation of some antioxidants in salame Milano and mortadella production. PubMed: Sesamol as an inhibitor of growth and lipid metabolism in Mucor circinelloides via its action on malic enzyme. PubMed: Formation of the mutagenic/carcinogenic imidazoquinoxaline-type heterocyclic amines through the unstable free radical Maillard intermediates and its inhibition by phenolic antioxidants. PubMed: The prevention of CCl4-induced liver necrosis in mice by naturally occurring methylenedioxybenzenes. PubMed: Antioxidative effect of sesamol and related compounds on lipid peroxidation. PubMed: Effect of plant phenolics on the formation of the spin-adduct of hydroxyl radical and the DNA strand breaking by hydroxyl radical. PubMed: Inhibitory effects of phenolic compounds on development of naturally occurring preneoplastic hepatocytic foci in long-term feeding studies using male F344 rats. PubMed: [Protective effects of sesamol and its related compounds on carbon tetrachloride induced liver injury in rats]. PubMed: EPR and TREPR spectroscopic studies of antioxidant sesamolyl and related phenoxyl radicals. PubMed: Cell proliferation and forestomach carcinogenesis. PubMed: Comparison of reversibility of rat forestomach lesions induced by genotoxic and non-genotoxic carcinogens. PubMed: Organ-specific modification of carcinogenesis by antioxidants in rats. PubMed: Forestomach neoplasm induction in F344/DuCrj rats and B6C3F1 mice exposed to sesamol. PubMed: Regiochemical differences in cytochrome P450 isozymes responsible for the oxidation of methylenedioxyphenyl groups by rabbit liver. PubMed: Suppression of diethylnitrosamine-initiated preneoplastic foci development in the rat liver by combined administration of four antioxidants at low doses. PubMed: Aromatic hydroxylation of methylenedioxybenzene (MDB) and methylenedioxymethamphetamine (MDMA) by rabbit liver microsomes. PubMed: Changes of ingredients in the process of cooking of sesame oil. PubMed: In vitro assessment of the structure-activity relationship of tyrosinase-dependent cytotoxicity of a series of substituted phenols. PubMed: [Studies on chemical protectors against radiation. XXXIII. Protective mechanisms of various compounds against skin injury induced by radiation]. PubMed: [Protective effects of antioxidants on experimental liver injuries]. PubMed: Stomach carcinogenicity of caffeic acid, sesamol and catechol in rats and mice. PubMed: Antioxidants--carcinogenic and chemopreventive properties. PubMed: Is sesamol present in sesame oil? PubMed: Induction of forestomach lesions in rats by oral administrations of naturally occurring antioxidants for 4 weeks. PubMed: Inhibition of rabbit nasal and hepatic cytochrome P-450-dependent hexamethylphosphoramide (HMPA) N-demethylase by methylenedioxyphenyl compounds. PubMed: Interaction of hemoglobin A with sesamol and polyphenolics. PubMed: Transformation of hemoglobin A into methemoglobin by sesamol. PubMed: Coupling between oxidative metabolism and active transport in the midgut of tobacco hornworm. PubMed: Autoxidation in milk rich in linoleic acid. I. An objective method of measuring autoxidation and evaluating antioxidants. PubMed: Allergens in sesame oil contact dermatitis. PubMed: Sesamol transport by human blood.