sodium bisulfite

sodium hydrogen sulphite

CAS: 7631-90-5 Na O3 S - MW: 105.06884930

Identification

Namesodium bisulfite
IUPACsodium sulfite
CAS Number7631-90-5
EINECS231-548-0
FDA UNIITZX5469Z6I
Molecular FormulaNa O3 S -
Molecular Weight105.06884930

Regulatory

FDA/DG SANTE Petitions, Reviews, Notices182.3739
JECFA Food AdditiveSodium Hydrogen Sulfite
GSFA CodexSodium hydrogen sulfite (222)
DG SANTE Food Additivessodium hydrogen sulphite
DG SANTE Food Contact Materialssodium hydrogen sulphite
FDA Mainterm (SATF)7631-90-5 ; SODIUM BISULFITE
FDA RegulationFDA PART 161 -- FISH AND SHELLFISH

Physical Properties

Appearance white crystalline powder (est)
Assay 85.00 to 100.00
Food Chemicals Codex Listed No
Specific Gravity 1.48000 @ 25.00 °C.
Soluble in water, 1e+006 mg/L @ 25 °C (est)

Cosmetic Information

CosIngcosmetic data
Cosmetic Usesantioxidants

No sensory data available

Safety Information

Oral/Parenteral Toxicityintravenous-rat LD50 115 mg/kg
Dermal ToxicityNot determined
Inhalation ToxicityNot determined

GHS Classification

['GHS Classification in accordance with 29 CFR 1910 (OSHA HCS)', 'GHS Label elements, including precautionary statements', 'BEHAVIORAL: ALTERED SLEEP TIME (INCLUDING CHANGE IN RIGHTING REFLEX)\nBEHAVIORAL: CONVULSIONS OR EFFECT ON SEIZURE THRESHOLD']

Safety in Use

Categoryantibrowning agents, antioxidants, preservatives
Recommendation for sodium bisulfite usage levels up tonot for fragrance use.
Recommendation for sodium bisulfite flavor usage levels up tonot for flavor use.

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Penta International Corporation

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Potential Uses

preservatives

Natural Occurrence

not found in nature

Synonyms

hydrogen sodium sulfite sodium bisulphite sodium hydrogen sulfite sodium hydrogen sulphite sodium sulfite (1:1) sulfurous acid monosodium salt sulfurous acid sodium salt (1:1) sulfurous acid, sodium salt (1:1) PubMed: Investigation of the use of Maillard reaction inhibitors for the production of patatin-carbohydrate conjugates. PubMed: Effect of processing on mycotoxin content in grains. PubMed: The antibrowning agent sulfite inactivates Agaricus bisporus tyrosinase through covalent modification of the copper-B site. PubMed: Chemical treatments for reducing the yellow discoloration of channel catfish (Ictalurus punctatus) fillets. PubMed: Characterization of three deoxynivalenol sulfonates formed by reaction of deoxynivalenol with sulfur reagents. PubMed: Short communication: Reducing agents attenuate methylglyoxal-based browning in Parmesan cheese. PubMed: Chemical composition and functional properties of native chestnut starch (Castanea sativa Mill). PubMed: High titer ethanol production from SPORL-pretreated lodgepole pine by simultaneous enzymatic saccharification and combined fermentation. PubMed: Determination of andrograpolide sodium bisulphite in Beagle dog plasma by LC-MS/MS and its application to pharmacokinetics. PubMed: Inhibition of enzymatic browning of chlorogenic acid by sulfur-containing compounds. PubMed: Isolation of glycinin (11S) from lipid-reduced soybean flour: effect of processing conditions on yields and purity. PubMed: Quantification of andrographolide sodium bisulphite in urine after intravenous injection to rats by LC-MS/MS. PubMed: New insights into an ancient antibrowning agent: formation of sulfophenolics in sodium hydrogen sulfite-treated potato extracts. PubMed: Anthocyanins remain stable during commercial blackcurrant juice processing. PubMed: The effect of chemical treatment on reduction of aflatoxins and ochratoxin A in black and white pepper during washing. PubMed: Effects of sulfur dioxide derivatives on expression of oncogenes and tumor suppressor genes in human bronchial epithelial cells. PubMed: Effect of sodium bisulfite on properties of soybean glycinin. PubMed: Determination of free and reversibly-bound sulfite in selected foods by high-performance liquid chromatography with fluorometric detection. PubMed: Study on the electrochemiluminescent behavior of menadione sodium bisulfite in presence of luminol. PubMed: Sources of variability of acrylamide levels in a cracker model. PubMed: Aspergillus flavus growth in the presence of chemical preservatives and naturally occurring antimicrobial compounds. PubMed: Detailed investigation of the production of the bread flavor component 6-acetyl-1,2,3,4-tetrahydropyridine in proline/1,3-dihydroxyacetone model systems. PubMed: Use of DNA from human stools to detect aberrant CpG island methylation of genes implicated in colorectal cancer. PubMed: Effect of menadione sodium bisulfite, an inducer of plant defenses, on the dynamic of banana phytoalexin accumulation during pathogenesis. PubMed: A model system study of the inhibition of heterocyclic aromatic amine formation by organosulfur compounds. PubMed: [Changes in serum enzymes in rats treated with sodium bisulfite]. PubMed: Effects of dietary vitamin K on survival, growth, and tissue concentrations of phylloquinone (PK) and menaquinone-4 (MK-4) for juvenile abalone, Haliotis discus hannai Ino. PubMed: Determination of potato glycoalkaloids using a liposome immunomigration, liquid-phase competition immunoassay. PubMed: Utilization of highly deoxynivalenol-contaminated wheat via extrusion processing. PubMed: Shelf life of sliced raw potatoes of various cultivar varieties--substitution of bisulfites. PubMed: The role of sodium bisulfite in the 1996-1997 USA influenza vaccine recall. PubMed: [Effect of cooking on protein digestibility of sorghum (Sorghum bicolor (L.) Moench)]. PubMed: Shelf-life of prepeeled potato cultivated, stored, and processed by various methods. PubMed: Simple high-performance liquid chromatographic method for the determination of all seven vitamin B6-related compounds. PubMed: [Prevalence of chronic urticaria following the ingestion of food additives in a third tier hospital]. PubMed: Fate of aflatoxins B1 and G 1 residues during biscuit processing. PubMed: Fate of fumonisins B1 and B2 in steeped corn kernels. PubMed: Differential sensitivity to loss of cytosine methyl groups within the hepatic p53 gene of folate/methyl deficient rats. PubMed: Sodium metabisulfite and SO2 release: an under-recognized hazard among shrimp fishermen. PubMed: Inhibition studies on liver arylformamidases of rainbow trout and cattle. PubMed: Mutagenicity of Maillard reaction products from D-glucose-amino acid mixtures and possible roles of active oxygens in the mutagenicity. PubMed: The use of trichothecene-contaminated grains in feeds. PubMed: [A case of asthma exacerbated by sulfite contained in betamethasone]. PubMed: Oral provocation tests with aspirin and food additives in asthmatic patients. PubMed: Fluorimetric determination of vitamin K3 (menadione sodium bisulfite) in synthetic animal feed by high-performance liquid chromatography using a post-column zinc reducer. PubMed: Sulfite-treated lettuce challenges in sulfite-sensitive subjects with asthma. PubMed: Simple isocratic high-performance liquid chromatographic method for the separation of the six vitamers of vitamin B6. PubMed: Production of Acetaldehyde by Zymomonas mobilis. PubMed: Sulfites and skin pathology in children. PubMed: Improving the in vitro protein digestibility of sorghum with reducing agents. PubMed: Provocative testing for sulfite sensitivity in clinical allergy. PubMed: Sodium bisulfite protects against radiogenic and chemically induced transformation in hamster embryo and mouse C3H/10T-1/2 cells. PubMed: Inhibition by antimicrobial food additives of ochratoxin A production by Aspergillus sulphureus and Penicillium viridicatum. PubMed: Stability of thiamin in parenteral nutrition solutions. PubMed: A study of the induction of gene conversion in yeast by sodium bisulphite under radical reaction conditions. PubMed: Fast atom bombardment mass spectrometry of aflatoxins and reaction products of sodium bisulfite with aflatoxins. PubMed: Sulfite suppresses the mutagenic property of coffee. PubMed: Anaphylaxis to a component of isoetharine (sodium bisulfite). PubMed: Spectrophotometric method for hydroxymethylfurfural in honey. PubMed: Crosslinking of nucleic acids and proteins by bisulfite. PubMed: Anaphylaxis after ingestion of sodium bisulfite. PubMed: Survival and recovery of enterovirus from foods.