sodium ethoxide
ethanol, sodium salt (1:1)
Identification
| Name | sodium ethoxide |
| IUPAC | sodium;ethanolate |
| CAS Number | 141-52-6 |
| EINECS | 205-487-5 |
| FDA UNII | 1I9504387J |
| Molecular Formula | C2 H5 Na O |
| Molecular Weight | 68.05081928 |
| MDL Number | MFCD00012417 |
| Nikkaji Number | J91.259J |
| Beilstein | 3593646 |
Regulatory
Physical Properties
| Assay | 95.00 to 100.00 |
| Food Chemicals Codex Listed | No |
| Flash Point | 32.00 °F. TCC ( 0.00 °C. ) (est) |
| Soluble in | water, 1e+006 mg/L @ 25 °C (est) |
No sensory data available
Safety Information
| Preferred SDS | View |
| Oral/Parenteral Toxicity | Not determined |
| Dermal Toxicity | Not determined |
| Inhalation Toxicity | Not determined |
GHS Classification
['GHS Classification in accordance with 29 CFR 1910 (OSHA HCS)', 'GHS Label elements, including precautionary statements']
Safety in Use
| Category | pharmaceuticals / chemical synthisis |
| Recommendation for sodium ethoxide usage levels up to | not for fragrance use. |
| Recommendation for sodium ethoxide flavor usage levels up to | not for flavor use. |
Potential Uses
Natural Occurrence
Synonyms
caustic alcohol
ethanol, sodium salt
ethanol, sodium salt (1:1)
ethoxysodium
ethyl alcohol, sodium salt
sodium ethanolate
sodium ethylate
sodium;ethanolate
US Patents:
7,927,643 - Compositions of oxo-terpene derivatives and process for preparing the same
PubMed:
Heat-induced Antigen Retrieval in Conventionally Processed Epon-embedded Specimens: Procedures and Mechanisms.
PubMed:
Fragment-based approach to the design of 5-chlorouracil-linked-pyrazolo[1,5-a][1,3,5]triazines as thymidine phosphorylase inhibitors.
PubMed:
Synthesis and antimicrobial evaluation of some novel bis-α,β-unsaturated ketones, nicotinonitrile, 1,2-dihydropyridine-3-carbonitrile, fused thieno[2,3-b]pyridine and pyrazolo[3,4-b]pyridine derivatives.
PubMed:
A solvent free, four-component synthesis and 1,3-dipolar cycloaddition of 4(H)-pyrans with nitrile oxides: synthesis and discovery of antimycobacterial activity of enantiomerically pure 1,2,4-oxadiazoles.
PubMed:
Catalytic enantioselective N-nitroso aldol reaction of γ,δ-unsaturated δ-lactones.
PubMed:
The evaluation of various kinetic models for base-catalyzed ethanolysis of palm oil.
PubMed:
A green expedient synthesis of pyridopyrimidine-2-thiones and their antitubercular activity.
PubMed:
Synthesis and biological activity of 2-(bis((1,3,4-oxadiazolyl/1,3,4-thiadiazolyl)methylthio)methylene)malononitriles.
PubMed:
Rapid synthesis of flavor compound 4-ethyloctanoic acid under microwave irradiation.
PubMed:
Synthesis of 3-(quinolin-2-yl)- and 3,6-bis(quinolin-2-yl)-9H-carbazoles.
PubMed:
Synthesis and pharmacological evaluation of novel substituted and unsubstituted N-(benzoylphenyl)-1H-indole-2-carboxamides as potent antihypertriglyceridemic agents.
PubMed:
9,10-Dioxa-1,2-diaza-anthracene derivatives from tetrafluoropyridazine.
PubMed:
Chemical synthesis and characterization of palm oil-based difatty acyl thiourea.
PubMed:
Ethanolysis of N-substituted norbornane epoxyimides: discovery of diverse pathways depending on substituent's character.
PubMed:
Synthesis, X-ray crystal structure study and antitumoral evaluations of 5,6-disubstituted pyrimidine derivatives.
PubMed:
Difatty acyl urea from corn oil: synthesis and characterization.
PubMed:
Catalytic asymmetric three-component Mannich-type reaction of alkenyl trichloroacetates.
PubMed:
Bifunctional heterogeneous catalysis of silica-alumina-supported tertiary amines with controlled acid-base interactions for efficient 1,4-addition reactions.
PubMed:
Synthesis and characterization of N,N'-carbonyl difatty amides from palm oil.
PubMed:
Synthesis of some new 1,3,4-thiadiazol-2-ylmethyl-1,2,4-triazole derivatives and investigation of their antimicrobial activities.
PubMed:
Self-assembly and characterization of a novel 2D network polymer containing a 60-membered organotin macrocycle.
PubMed:
Tuning of chemo- and regioselectivities in multicomponent condensations of 5-aminopyrazoles, dimedone, and aldehydes.
PubMed:
Synthesis of an isomeric mixture (24RS,25RS) of sodium scymnol sulfate.
PubMed:
Unusual condensation of 3-Thia[5](1,1')ferrocenophane-1,5-dione with glyoxal. Formation of [1.1](2,3)thiopheno(1,1')ferrocenophane-1,7-dione.
PubMed:
Surface roughness analysis of fiber post conditioning processes.
PubMed:
Nitric oxide reacts with methoxide.
PubMed:
A general stereoselective method for the synthesis of cyclopropanecarboxylates. A new version of the homologous Horner-Wadsworth-Emmons reaction.
PubMed:
Regioselective synthesis and antitumor screening of some novel N-phenylpyrazole derivatives.
PubMed:
An atom efficient, solvent-free, green synthesis and antimycobacterial evaluation of 2-amino-6-methyl-4-aryl-8-[(E)-arylmethylidene]-5,6,7,8-tetrahydro-4H-pyrano[3,2-c]pyridine-3-carbonitriles.
PubMed:
First example of 5/6-O-linked pseudosaccharides: synthesis of bicyclic nucleosides containing azido or extended carbohydrate moiety.
PubMed:
Novel regioselective formation of S- and N-hydroxyl-alkyls of 5-(3-chlorobenzo[b]thien-2-yl)-3-mercapto-4H-1,2,4-triazole and a facile synthesis of triazolo-thiazoles and thiazolo-triazoles. Role of catalyst and microwave.
PubMed:
Novel regioselective hydroxyl-alkylation of 4,5-diphenylimidazole-2-thione and a competitive intramolecular ring closure of the S-hydroxyalkyl-imidazoles to imidazo[2,1-b]thiazines and thiazoles. Role of catalyst, microwave irradiation, and solid support.
PubMed:
The intensity of immunogold labeling of deplasticized acrylic sections compared to deplasticized epoxy sections-Theoretical deductions and experimental data.
PubMed:
Optimization of biodiesel production from castor oil.
PubMed:
Synthesis and characterization of alkoxide-derived pt nanoparticles.
PubMed:
Synthesis of 3-hydroxy-6-oxo[1,2,4]triazin-1-yl alaninamides, a new class of cyclic dipeptidyl ureas.
PubMed:
Improving the quality of the quartz fiber postcore bond using sodium ethoxide etching and combined silane/adhesive coupling.
PubMed:
Use of anti-fluorophore antibody to achieve high-sensitivity immunolocalizations of transporters and ion channels.
PubMed:
Improved access to 2-O-monobenzyl ethers of beta-cyclodextrin as precursors of catalysts for organophosphoryl esters hydrolysis.
PubMed:
Novel immobilization of titanium dioxide (TiO2) on the fluidizing carrier and its application to the degradation of azo-dye.
PubMed:
Post-surface conditioning improves interfacial adhesion in post/core restorations.
PubMed:
Aminoparathion: a highly reactive metabolite of parathion. 1. Reactions with polyphenols and polyphenol oxidase.
PubMed:
Self-assembly of dialkyltin moieties and mercaptobenzoic acid into macrocyclic complexes with hydrophobic "pseudo-cage" or double-cavity structures: supramolecular infrastructures involving intermolecular C-H...S weak hydrogen bonds and pi-pi interactions.
PubMed:
Extractive spectrofluorometric determination of quinalphos using fluorescein in environmental samples.
PubMed:
Immunohistochemical staining of epoxy resin sections of peripheral nerve.
PubMed:
Susceptibility of a polycaprolactone-based root canal filling material to degradation. I. Alkaline hydrolysis.
PubMed:
Synthesis of new triazolopyrimidines and substituted pyrimidines.
PubMed:
Investigations of a novel process to the framework of benzo[c]cinnoline.
PubMed:
Antibacterial and bioactive silver-containing Na2O x CaO x 2SiO2 glass prepared by sol-gel method.
PubMed:
Self-assembly of diorganotin(IV) moieties and 2-pyrazinecarboxylic acid: syntheses, characterizations and crystal structures of monomeric, polymeric or trinuclear macrocyclic compounds.
PubMed:
Synthesis and in vitro antimicrobial activities of 2-hydroxy-6-methyl-7-(arylamino)-1,7-dihydropurin-8-ones.
PubMed:
Fluorometric variable-temperature kinetics investigations of the transesterification reaction of procaine with aliphatic alcohols.
PubMed:
Regioselective enzyme-catalyzed synthesis of sophorolipid esters, amides, and multifunctional monomers.
PubMed:
Alkylation of the inverted porphyrin nickel(II) complex by dihalogenalkanes: formation of monomeric and dimeric derivatives.
PubMed:
Electronic effects and the stereochemistries in rearrangement-displacement reactions of triaryl(halomethyl)silanes with fluoride and with alkoxide ions.
PubMed:
Immunofluorescence technique for 100-nm-thick semithin sections of Epon-embedded tissues.
PubMed:
Multiplicity control in the polygeminal diazeniumdiolation of active hydrogen bearing carbons: chemistry of a new type of trianionic molecular propeller.
PubMed:
Synthesis of 1,2-unsaturated pyranosylphosphonate nucleosides from 3,4,6-tri-O-acetyl-D-glycal.
PubMed:
Re-evaluation of epoxy resin sections for light and electron microscopic immunostaining.
PubMed:
Synthesis, reactions and antimicrobial activity of new cyclopenta[e]thieno[2,3-b]pyridines and related heterocyclic systems.
PubMed:
Deplasticizing or etching of epoxy sections with different concentrations of sodium ethoxide to enhance the immunogold labeling.
PubMed:
Bioactivation mechanisms of haloalkene cysteine S-conjugates modeled by gas-phase, ion-molecule reactions.
PubMed:
Comparison of the immunolabeling of heated and deplasticized epoxy sections on the electron microscopical level.
PubMed:
Diaminobenzidine as a myelin stain in semithin plastic sections.
PubMed:
Antigen detection on resin sections and methods for improving the immunogold labeling by manipulating the resin.
PubMed:
Effective GC-MS procedure for detecting iso-LSD in urine after base-catalyzed conversion to LSD.
PubMed:
Pre-osteoblastic proliferation assessed with BrdU in undecalcified, Epon-embedded adult rat trabecular bone.
PubMed:
Synthesis and antiproliferative and antiviral activity of carbohydrate-modified pyrrolo[2,3-d]pyridazin-7-one nucleosides.
PubMed:
How to examine the antigen-damaging effect of sodium ethoxide on deplasticized epoxy sections.
PubMed:
Preparation and characterization of alkylated poly(vinyl alcohol) hydrogels using alkyl halides.
PubMed:
Furanfurin and thiophenfurin: two novel tiazofurin analogues. Synthesis, structure, antitumor activity, and interactions with inosine monophosphate dehydrogenase.
PubMed:
Antigen unmasking for immunoelectron microscopy: labeling is improved by treating with sodium ethoxide or sodium metaperiodate, then heating on retrieval medium.
PubMed:
Mechanism for antigen detection on deplasticized epoxy sections.
PubMed:
Protein-ubiquinone interaction: synthesis and biological properties of ethoxy ubiquinone derivatives.
PubMed:
Immunocytochemical localization of delta 3, delta 2-enoyl-CoA isomerase and NADPH-dependent-2,4-dienoyl-CoA reductase in rat kidney.
PubMed:
Synthesis of some new 3-(2'-heterocyclicethyl)-2-methyl-3,4- dihydroquinazolin-4-one derivatives as antimicrobial agents.
PubMed:
Comparison of lectin reactivity in the vessel beds of the rat eye.
PubMed:
Photometric determination of malathion with molybdenum.
PubMed:
Bromodeoxyuridine (BrdUrd) immunohistochemistry in undecalcified plastic-embedded tissue. Elimination of the DNA denaturation step.
PubMed:
[Structure correction and synthesis of subspinosin].
PubMed:
Ultrastructural immunogold labeling of glial filaments in osmicated and unosmicated epoxy-embedded tissue.
PubMed:
Application of the avidin-biotin-peroxidase complex (ABC-peroxidase) technique to the identification of human papillomavirus antigens on semithin sections by electron microscopy.
PubMed:
Xanthine oxidase inhibition: effect of an N-alkyl substituent on C-2 of the nucleus of 8-azahypoxanthine.
PubMed:
On-grid immunogold labeling of glial intermediate filaments in epoxy-embedded tissue.
PubMed:
[Detection of fibronectin and collagen types I, III, IV and V in semithin sections of the human aorta].
PubMed:
Immunocytochemical localization of peroxisomal enzymes in human liver biopsies.
PubMed:
Partial characterization of lectin binding sites of retinal photoreceptor outer segments and interphotoreceptor matrix.
PubMed:
Immunocytochemical localization of the myelin-associated glycoprotein. Fact or artifact?
PubMed:
Light microscopic immunocytochemical demonstration of peroxisomal enzymes in epon sections.
PubMed:
Immunohistochemical localization of the delta antigen associated with hepatitis B virus in liver biopsy sections embedded in Araldite.
PubMed:
Immunohistochemistry of types I and II collagen in undecalcified skeletal tissues.
PubMed:
Differentiation of A-, B- and D-cells of guinea-pig pancreas using semi-thin epoxy-resin sections.
PubMed:
Retrospective demonstration of endogenous peroxidase activity in plastic-embedded tissues conventionally prepared for electron microscopy.
PubMed:
Post-embedding immunoperoxidase staining of glial fibrillary acidic protein for light and electron microscopy.
PubMed:
Analytical scanning electron microscopy and x-ray microdiffractometry of renal calculi using etched plastic sections.
PubMed:
New cyclopenta[a]naphthalene derivatives. Synthesis of 2-(carbamylmethyl)-8-hydroxy-3H-cyclopental[a]naphthalene as a possible deoxyribonucleic acid binding agent.
PubMed:
Total synthesis of stereospecific sphingosine and ceramide.
PubMed:
Immuno-electron-cytochemical localization of the somatostatin cells in the human antral mucosa.
PubMed:
Synthesis of certain 4-oxo-1.2.3.4-tetrahydroquinoline and benzazocine derivatives likely to possess analgesic activity.
PubMed:
[Determination of hexachlorocyclohexane by direct titration with sodium ethoxide in anhydrous medium].
PubMed:
[Research on nitrogen heterocyclic compounds. IX. Synthesis of 5-hydroxy-2,4-dicarbethoxypyrroles].
PubMed:
Reaction mechanism in aromatic heterocyclic compounds. X. Kinetics of the reaction of carcinogenic 4-nitroquinoline 1-oxide and its derivatives with sodium ethoxide.
PubMed:
Nucleosides. X. The action of sodium ethoxide on 3'-0-tosyl-2'-deoxyadenosine.
PubMed:
[A METHOD FOR ISOLATING SODIUM ETHOXIDE FROM ALCOHOL AND SOLID SODIUM HYDROXIDE].
PubMed:
[Studies on the syntheses of 4, 5-disubstituted isoxazoles and their cleavage reaction with sodium ethoxide. V. On the reactions of isoxazole and alpha-cyanoketone possessing furan ring].
PubMed:
On the preparation of optically active phenyl-p-tolyl-methanesulphonic acid and its racemisation by sodium ethoxide.