sodium hydrosulfite

dithionous acid sodium salt (1:2)

CAS: 7775-14-6 Na2 O4 S2 MW: 174.10633856

Identification

Namesodium hydrosulfite
IUPACdisodium dithionite
CAS Number7775-14-6
EINECS231-890-0
FDA UNII2K5B8F6ES1
Molecular FormulaNa2 O4 S2
Molecular Weight174.10633856
MDL NumberMFCD00011640
Nikkaji NumberJ41.404B

Regulatory

FDA/DG SANTE Petitions, Reviews, Notices182.90
FDA Mainterm (SATF)7775-14-6 ; SODIUM HYDROSULFITE
FDA RegulationFDA PART 176 -- INDIRECT FOOD ADDITIVES: PAPER AND PAPERBOARD COMPONENTS

Physical Properties

Food Chemicals Codex Listed No
Flash Point 32.00 °F. TCC ( 0.00 °C. ) (est)
logP (o/w) -2.756 (est)
Soluble in water, 1e+006 mg/L @ 25 °C (est)

Cosmetic Information

CosIngcosmetic data
Cosmetic Usesreducing agents

No sensory data available

Safety Information

Oral/Parenteral ToxicityNot determined
Dermal ToxicityNot determined
Inhalation ToxicityNot determined

GHS Classification

['GHS Classification in accordance with 29 CFR 1910 (OSHA HCS)', 'GHS Label elements, including precautionary statements']

Safety in Use

Categoryfood-contact surface of paper and paperboard
Recommendation for sodium hydrosulfite usage levels up tonot for fragrance use.
Recommendation for sodium hydrosulfite flavor usage levels up tonot for flavor use.

ECSA Chemicals

Human Chemistry

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Potential Uses

reducing agents viscosity controlling agents

Natural Occurrence

not found in nature

Synonyms

disodium dithionate disodium dithionite disodium hydrosulfite dithionous acid sodium salt (1:2) dithionous acid, disodium salt sodium dithionite sodium hydrosulphite sodium hyposulfite sodiumdithionite vatrolite PubMed: Effect of near-infrared irradiation on photoconversion of the water-soluble chlorophyll-binding protein of Chenopodium album. PubMed: Neuroprotective effects of gallic acid against hypoxia/reoxygenation-induced mitochondrial dysfunctions in vitro and cerebral ischemia/reperfusion injury in vivo. PubMed: Effects of a hydrogen sulfide donor on spontaneous contractile activity of rat stomach and jejunum. PubMed: Comparative study of bioactivity of collagen scaffolds coated with graphene oxide and reduced graphene oxide. PubMed: Spectroscopic evidence for a 5-coordinate oxygenic ligated high spin ferric heme moiety in the Neisseria meningitidis hemoglobin binding receptor. PubMed: Effects of hypoxia on progranulin expression in HT22 mouse hippocampal cells. PubMed: Comparison of the protective effects of ferulic acid and its drug-containing plasma on primary cultured neonatal rat cardiomyocytes with hypoxia/reoxygenation injury. PubMed: Using Chemical Release Surveillance Data to Evaluate the Public Health Impacts of Chlorine and Its Alternatives. PubMed: Determination of benzo[a]pyrene-7,10-quinone in airborne particulates by using a chemiluminescence reaction of hydrogen peroxide and hydrosulfite. PubMed: Enhancing effect of alcoholic solvent on hydrosulfite-hydrogen peroxide chemiluminescence system. PubMed: Graphene oxide adsorption enhanced by in situ reduction with sodium hydrosulfite to remove acridine orange from aqueous solution. PubMed: Analysis of hazardous organic residues from sodium hydrosulfite industry and utilization as raw materials in a novel solid lubricant production. PubMed: Hydrogen peroxide-sodium hydrosulfite chemiluminescence system combined with high-performance liquid chromatography for determination of 1-hydroxypyrene in airborne particulates. PubMed: [Determination of primary aromatic amines in crayons gas chromatography-mass spectrometry]. PubMed: The effect of chemical treatment on reduction of aflatoxins and ochratoxin A in black and white pepper during washing. PubMed: Effect of reduced sulfur compounds on the fermentation of phosphoric acid pretreated sugarcane bagasse by ethanologenic Escherichia coli. PubMed: [Synthesis of 2-amino-4, 5-diarylpyrimidines and their protective effects against oxygen-glucose deprivation in PC12 cells]. PubMed: A simple and efficient method to prepare graphene by reduction of graphite oxide with sodium hydrosulfite. PubMed: Efficient identification and quantification of peptides containing nitrotyrosine by matrix-assisted laser desorption/ionization time-of-flight mass spectrometry after derivatization. PubMed: Validation of a spectrophotometric method for quantification of carboxyhemoglobin. PubMed: Consideration of molecular arrangements in regio- and enantioselective reduction of an NAD model compound controlled by carbonyl oxygen orientation. PubMed: Ph3As-catalyzed wittig-type olefination of aldehydes with diazoacetate in the presence of Na2S2O4. PubMed: Rapid and sensitive HPLC method for the simultaneous determination of paraquat and diquat in human serum. PubMed: Detection of 6-nitrotryptophan in proteins by Western blot analysis and its application for peroxynitrite-treated PC12 cells. PubMed: Purification and some properties of sulfur reductase from the iron-oxidizing bacterium Thiobacillus ferrooxidans NASF-1. PubMed: Identification of factors involved in recovery of heat-injured Salmonella Enteritidis. PubMed: Microplate assay measurement of cytochrome p450-carbon monoxide complexes. PubMed: O2-specific regulation of the ferrous heme-based sensor kinase FixL from Sinorhizobium meliloti and its aberrant inactivation in the ferric form. PubMed: [Determination of anions in recycle sodium formate from sodium hydrosulfite industry with single column ion chromatography]. PubMed: 8-nitroguanosine formation in viral pneumonia and its implication for pathogenesis. PubMed: Effects of oxidizing adulterants on detection of 11-nor-delta9-THC-9-carboxylic acid in urine. PubMed: A Redox-Sensitive Resin Linker for the Solid Phase Synthesis of C-Terminal Modified Peptides. PubMed: Synthesis of 2-phenylbenzotriazole-type mutagens, PBTA-5 and PBTA-6, and their detection in river water from Japan. PubMed: Purification and characterization of chorion peroxidase from Aedes aegypti eggs. PubMed: Highly sensitive high-performance liquid chromatographic assay for methotrexate in the presence and absence of anti-methotrexate antibody fragments in rat and mouse plasma. PubMed: Determination of organic anions in waste liquid of sodium hydrosulfite production by ion chromatography. PubMed: Nitric oxide inhibits L-type Ca2+ current in glomus cells of the rabbit carotid body via a cGMP-independent mechanism. PubMed: The kinetics of the reaction between NO and O2 as studied by a novel approach. PubMed: Immobilization of N-carbamyl-D-amino acid amidohydrolase. PubMed: Sodium hydrosulfite contractions of smooth muscle are calcium and myosin phosphorylation independent. PubMed: Chemical synthesis of a novel aromatic amine mutagen isolated from water of the Nishitakase River in Kyoto and a possible route of its formation. PubMed: Horseradish peroxidase-dependent oxidation of deuteroporphyrin IX into chlorins. PubMed: Evidence for a novel heme adduct generated by the in vitro reaction of 2,4,6-trinitrotoluene with human hemoglobin using electrospray ionization mass spectrometry. PubMed: [Syntheses and spectra of Mn(III)-chlorophyll-a and Mn(II)-chlorophyll-a]. PubMed: Monophosphoryl lipid A protects adult rat cardiac myocytes with induction of the 72-kD heat shock protein: a cellular model of pharmacologic preconditioning. PubMed: Extensive tyrosine nitration in human myocardial inflammation: evidence for the presence of peroxynitrite. PubMed: Nucleotide-selective cleavage of duplex DNA by nitric oxide. PubMed: Evidence for in vivo peroxynitrite production in human acute lung injury. PubMed: In search of the real respiratory neurons: culture of medullary fetal cells sensitive to CO2 and low pH. PubMed: Phosphorylation and Dephosphorylation of Guard-Cell Proteins from Vicia faba L. in Response to Light and Dark. PubMed: Oxygen tension clamp around single neurons in vitro: a computerized method for studies on O2 deprivation. PubMed: In search of the central respiratory neurons: II. Electrophysiologic studies of medullary fetal cells inherently sensitive to CO2 and low pH. PubMed: Isolation of 6-mercaptopurine in human plasma by aluminum ion complexation for high-performance liquid chromatographic analysis. PubMed: Induction of chalcone synthase in cell suspension cultures of carrot (Daucus carota L. spp. sativus) by ultraviolet light: evidence for two different forms of chalcone synthase. PubMed: Endogenous ethylene production is a potential problem in the measurement of nitrogenase activity associated with excised corn and sorghum roots. PubMed: Brain hemosiderin and superficial siderosis of the central nervous system. PubMed: Characterization of the autofluorescence of rat liver plasma membranes. PubMed: Hydrogen transfer by NADPH-dependent reductases in elongation of very-long-chain saturated and polyunsaturated fatty-acyl-CoA in swine cerebral microsomes. PubMed: Cross-linking study of the quaternary fine structure of mitochondrial F1-ATPase. PubMed: Spectrophotometric study on the oxidation of rutin by horseradish peroxidase and characteristics of the oxidized products. PubMed: Simplified determination of carboxyhemoglobin. PubMed: A simple spectrophotometry for determination of carboxyhemoglobin in blood. PubMed: [Analysis of drug decomposition products. XXXVI. Spectrophotometric method of the simultaneous determination of vitamin K3 and its sodium hydrosulfite component]. PubMed: Evaluation of a chemical technique for determining the oxygen permeability of synthetic membranes. PubMed: Induction of single strand scission in bacteriophage phi X174 replicative form I DNA by mitomycin C. PubMed: Inactivation of bacteriophage phi X174 by mitomycin C in the presence of sodium hydrosulfite and cupric ions. PubMed: Characterization of a flavoprotein iodotyrosine deiodinase from bovine thyroid. Flavin nucleotide binding and oxidation-reduction properties. PubMed: Spectrophotometric measurement of carboxyhemoglobin and methemoglobin in blood. PubMed: Structure of nanaomycin E, a new nanaomycin. PubMed: A new screening method for cystinuria. A simple and safe screening kit. PubMed: Azo reduction of trypan blue to a known carcinogen by a cell-free extract of a human intestinal anaerobe. PubMed: Folate analogues altered in the C9-N10 bridge region. 10-Oxafolic acid and 10-oxaaminopterin. PubMed: Synthesis of N-10-methyl-4-thiofolic acid and related compounds. PubMed: Metabolism of uronic acids in plant tissues: partial purification and properties of uronic Acid oxidase from citrus leaves. PubMed: [Radiation-protective action of sodium hydrosulfite and metabisulfite]. PubMed: [Electrophoretic separation of tissue proteins on polyacrylamide gel, prepared by use of sodium hydrosulfite as initiator of polymerization]. PubMed: Oxidation of D-amino acids by a particulate enzyme from Pseudomonas aeruginosa. PubMed: PURIFICATION OF THE SOLUBLE HEMOLYSINS OF LISTERIA MONOCYTOGENES. PubMed: FORMATE--PYRUVATE EXCHANGE REACTION IN STREPTOCOCCUS FAECALIS. II. REACTION CONDITIONS FOR CELL EXTRACTS. PubMed: Protection by sodium hydrosulfite against x-ray-induced mitotic inhibition in grasshopper neuroblast. PubMed: Reduction of the x-ray sensitivity of escherichia coli by sodium hydrosulfite and certain other inorganic sulfur compounds. PubMed: Reduction of x-ray sensitivity of Escherichia coli B/r by sulfhydryl compounds, alcohols, glycols, and sodium hydrosulfite. PubMed: Interference With the Antibacterial Action of Streptomycin by Reducing Agents. PubMed: STUDIES ON THE MECHANISM OF ANTIBACTERIAL ACTION OF 2-METHYL-1,4-NAPHTHOQUINONE. PubMed: STUDIES ON THE OXIDATION AND REDUCTION OF IMMUNOLOGICAL SUBSTANCES : I. PNEUMOCOCCUS HEMOTOXIN.