succinimide
3,4-dihydropyrrole-2,5-dione
Identification
| Name | succinimide |
| IUPAC | pyrrolidine-2,5-dione |
| CAS Number | 123-56-8 |
| EINECS | 204-635-6 |
| FDA UNII | 10X90O3503 |
| Molecular Formula | C4 H5 N O2 |
| Molecular Weight | 99.08925000 |
| MDL Number | MFCD00005495 |
| Nikkaji Number | J25.395B |
| Beilstein | 0108440 |
Regulatory
Physical Properties
| Assay | 95.00 to 100.00 |
| Food Chemicals Codex Listed | No |
| Melting Point | 126.50 °C. @ 760.00 mm Hg |
| Boiling Point | 288.00 °C. @ 760.00 mm Hg |
| Vapor Pressure | 0.002000 mmHg @ 25.00 °C. (est) |
| Flash Point | 320.00 °F. TCC ( 160.00 °C. ) (est) |
| logP (o/w) | -1.174 (est) |
| Soluble in | water, 1.96E+05 mg/L @ 21C (exp) |
No sensory data available
Safety Information
| Preferred SDS | View |
| Oral/Parenteral Toxicity | intravenous-mouse LD50 320 mg/kg |
| Dermal Toxicity | Not determined |
| Inhalation Toxicity | Not determined |
GHS Classification
['GHS Classification in accordance with 29 CFR 1910 (OSHA HCS)', 'GHS Label elements, including precautionary statements', 'U.S. Army Armament Research & Development Command, Chemical Systems Laboratory, NIOSH Exchange Chemicals. Vol. NX#03763']
Safety in Use
| Category | pharmaceuticals / chemical synthisis |
| Recommendation for succinimide usage levels up to | not for fragrance use. |
| Recommendation for succinimide flavor usage levels up to | not for flavor use. |
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Potential Uses
Natural Occurrence
Synonyms
dihydro-3-pyrroline-2,5-dione
3,4-
dihydropyrrole-2,5-dione
3,4-
dihydropyrrolidine
2,5-
dioxopyrrolidine
pyrrolidine-2,5-dione
2,5-
pyrrolidinedione
succinic acid imide
PubMed:
UV-photoconversion of ethosuximide from a longevity-promoting compound to a potent toxin.
PubMed:
Molecular products from the thermal degradation of glutamic acid.
PubMed:
Quantum dot loaded liposomes as fluorescent labels for immunoassay.
PubMed:
An electrochemical DNA microbiosensor based on succinimide-modified acrylic microspheres.
PubMed:
A biosensor for urea from succinimide-modified acrylic microspheres based on reflectance transduction.
PubMed:
A monoclonal antibody-based immunosensor for detection of Sudan I using electrochemical impedance spectroscopy.
PubMed:
A potentiometric formaldehyde biosensor based on immobilization of alcohol oxidase on acryloxysuccinimide-modified acrylic microspheres.
PubMed:
Specific detection and quantitative enumeration of Listeria spp. using fluorescent in situ hybridization in combination with filter cultivation (FISHFC).
PubMed:
Development of a novel immunobiosensor method for the rapid detection of okadaic acid contamination in shellfish extracts.
PubMed:
Determination of glucosamine in raw materials and dietary supplements containing glucosamine sulfate and/or glucosamine hydrochloride by high-performance liquid chromatography with FMOC-Su derivatization: collaborative study.
PubMed:
Racemization of an asparagine residue during peptide deamidation.
PubMed:
Generation of group-specific antibodies against sulfonamides.
PubMed:
Generation of class-selective monoclonal antibodies against the penicillin group.
PubMed:
A novel chitosan derivative to immobilize alpha-L-rhamnopyranosidase from Aspergillus niger for application in beverage technologies.
PubMed:
LDL-mediated interaction of Lp[a] with HepG2 cells: a novel fluorescence microscopy approach.
PubMed:
Aryl thioglycoside-based affinity purification of exo-acting cellulases.
PubMed:
Effects of methsuximide on schedule-controlled responding in the pigeon.
PubMed:
Aneuploidy induction in Saccharomyces cerevisiae by two solvent compounds, 1-methyl-2-pyrrolidinone and 2-pyrrolidinone.
PubMed:
Sensitive enzyme immunoassay of colistin and its application to detect residual colistin in rainbow trout tissue.
PubMed:
Effects of selective central muscarinic blockade on schedule-controlled behavior and on the rate-decreasing effects of physostigmine.
PubMed:
Nephrotoxicity following acute administration of N-(3,5-dichlorophenyl)succinimide in rats.
PubMed:
A method for improving the nutritional value of food proteins: covalent attachment of amino acids.