syringaldazine
benzaldehyde, 4-hydroxy-3,5-dimethoxy-, 2-((4-hydroxy-3,5-dimethoxyphenyl)methylene)hydrazone
Identification
| Name | syringaldazine |
| CAS Number | 14414-32-5 |
| EINECS | 238-390-1 |
| FDA UNII | Search |
| Molecular Formula | C18 H20 N2 O6 |
| Molecular Weight | 360.36660000 |
| MDL Number | MFCD00008363 |
| Nikkaji Number | J271B |
Regulatory
Physical Properties
| Appearance | pale yellow powder (est) |
| Assay | 96.00 to 100.00 |
| Food Chemicals Codex Listed | No |
| Melting Point | 209.00 to 210.00 °C. @ 760.00 mm Hg |
| Boiling Point | 534.08 °C. @ 760.00 mm Hg (est) |
| Flash Point | 530.00 °F. TCC ( 276.80 °C. ) (est) |
| logP (o/w) | 0.553 (est) |
| Soluble in | water, 21.06 mg/L @ 25 °C (est) |
No sensory data available
Safety Information
| European information | Most important hazard(s): |
| Oral/Parenteral Toxicity | Not determined |
| Dermal Toxicity | Not determined |
| Inhalation Toxicity | Not determined |
GHS Classification
['GHS Classification in accordance with 29 CFR 1910 (OSHA HCS)', 'GHS Label elements, including precautionary statements']
Safety in Use
| Category | information only not used for fragrances or flavors |
| Recommendation for syringaldazine usage levels up to | not for fragrance use. |
| Recommendation for syringaldazine flavor usage levels up to | not for flavor use. |
No supplier data available
Potential Uses
Natural Occurrence
Synonyms
benzaldehyde, 4-hydroxy-3,5-dimethoxy-, ((4-hydroxy-3,5-dimethoxyphenyl)methylene)hydrazone
benzaldehyde, 4-hydroxy-3,5-dimethoxy-, [(4-hydroxy-3,5-dimethoxyphenyl) methylene]hydrazone
benzaldehyde, 4-hydroxy-3,5-dimethoxy-, [(4-hydroxy-3,5-dimethoxyphenyl)methylene]hydrazone
benzaldehyde, 4-hydroxy-3,5-dimethoxy-, 2-((4-hydroxy-3,5-dimethoxyphenyl)methylene)hydrazone
4-[[2-[(3,5-
dimethoxy-4-oxidanylidene-cyclohexa-2,5-dien-1-ylidene)methyl]hydrazinyl]methylidene]-2,6-dimethoxy-cyclohexa-2,5-dien-1-one
4-[[(3,5-
dimethoxy-4-oxo-1-cyclohexa-2,5-dienylidene)methylhydrazo]methylidene]-2,6-dimethoxy-1-cyclohexa-2,5-dienone
4-[[2-[(3,5-
dimethoxy-4-oxocyclohexa-2,5-dien-1-ylidene)methyl]hydrazinyl]methylidene]-2,6-dimethoxycyclohexa-2,5-dien-1-one
4-
hydroxy-3,5-dimethoxybenzaldehyde azine
PubMed:
Expression and characterization of LacMP, a novel fungal laccase of Moniliophthora perniciosa FA553.
PubMed:
Expression, refolding, and characterization of a small laccase from Thermus thermophilus HJ6.
PubMed:
Purification, characterization and synthetic application of a thermally stable laccase from Hexagonia tenuis MTCC-1119.
PubMed:
Purification and Characterization of a Thermostable Laccase from Trametes trogii and Its Ability in Modification of Kraft Lignin.
PubMed:
Structural insight into the oxidation of sinapic acid by CotA laccase.
PubMed:
Overexpression of a novel thermostable and chloride-tolerant laccase from Thermus thermophilus SG0.5JP17-16 in Pichia pastoris and. its application in synthetic dye decolorization.
PubMed:
Aldehyde PEGylation of laccase from Trametes versicolor in route to increase its stability: effect on enzymatic activity.
PubMed:
Potential biological role of laccase from the sponge Suberites domuncula as an antibacterial defense component.
PubMed:
Substrate specificity and enzyme recycling using chitosan immobilized laccase.
PubMed:
Production, purification and biochemical characterization of two laccase isoforms produced by Trametes versicolor grown on oak sawdust.
PubMed:
Catalytic profile of Arabidopsis peroxidases, AtPrx-2, 25 and 71, contributing to stem lignification.
PubMed:
First laccase in green algae: purification and characterization of an extracellular phenol oxidase from Tetracystis aeria.
PubMed:
Expanding the laccase-toolbox: a laccase from Corynebacterium glutamicum with phenol coupling and cuprous oxidase activity.
PubMed:
Characterization of C-terminally engineered laccases.
PubMed:
Effect of enzymatic orientation through the use of syringaldazine molecules on multiple multi-copper oxidase enzymes.
PubMed:
Purification and characterization of an extracellular, thermo-alkali-stable, metal tolerant laccase from Bacillus tequilensis SN4.
PubMed:
Molecular modeling and docking of novel laccase from multiple serotype of Yersinia enterocolitica suggests differential and multiple substrate binding.
PubMed:
Engineering the expression and characterization of two novel laccase isoenzymes from Coprinus comatus in Pichia pastoris by fusing an additional ten amino acids tag at N-terminus.
PubMed:
Thermokinetic comparison of trypan blue decolorization by free laccase and fungal biomass.
PubMed:
Primary stress responses in Arabidopsis thaliana exposed to gamma radiation.
PubMed:
Identification of a laccase from Ganoderma lucidum CBS 229.93 having potential for enhancing cellulase catalyzed lignocellulose degradation.
PubMed:
Root antioxidant responses of two Pisum sativum cultivars to direct and induced Fe deficiency.
PubMed:
Enhancement of catalysis and functional expression of a bacterial laccase by single amino acid replacement.
PubMed:
Cloning and expression of thermo-alkali-stable laccase of Bacillus licheniformis in Pichia pastoris and its characterization.
PubMed:
Enzyme-based online monitoring and measurement of antioxidant activity using an optical oxygen sensor coupled to an HPLC system.
PubMed:
Characterization of the alkaline laccase Ssl1 from Streptomyces sviceus with unusual properties discovered by genome mining.
PubMed:
Purification and characterization of a new laccase from the filamentous fungus Podospora anserina.
PubMed:
Evidence for lignin oxidation by the giant panda fecal microbiome.
PubMed:
Prediction model based on decision tree analysis for laccase mediators.
PubMed:
Versatile peroxidase of Bjerkandera fumosa: substrate and inhibitor specificity.
PubMed:
Developing SyrinOX total antioxidant capacity assay for measuring antioxidants in humans.
PubMed:
Suspension cell culture as a tool for the characterization of class III peroxidases in sugarcane.
PubMed:
Heterologous expression and characterization of a novel laccase isoenzyme with dyes decolorization potential from Coprinus comatus.
PubMed:
Recombinant laccase: I. Enzyme cloning and characterization.
PubMed:
Enhanced archaeal laccase production in recombinant Escherichia coli by modification of N-terminal propeptide and twin arginine translocation motifs.
PubMed:
Laccase activity in soils: considerations for the measurement of enzyme activity.
PubMed:
Iodide oxidation by a novel multicopper oxidase from the alphaproteobacterium strain Q-1.
PubMed:
Recent developments and applications of immobilized laccase.
PubMed:
A new marine bacterial laccase with chloride-enhancing, alkaline-dependent activity and dye decolorization ability.
PubMed:
Laccase production by the aquatic ascomycete Phoma sp. UHH 5-1-03 and the white rot basidiomycete Pleurotus ostreatus DSM 1833 during submerged cultivation on banana peels and enzyme applicability for the removal of endocrine-disrupting chemicals.
PubMed:
Laccase- and peroxidase-free tyrosinase production by isolated microbial strain.
PubMed:
Mycorrhizal colonization alleviates drought-induced oxidative damage and lignification in the leaves of drought-stressed perennial ryegrass (Lolium perenne).
PubMed:
One-copper laccase-related enzyme from Marasmius sp.: purification, characterization and bleaching of textile dyes.
PubMed:
Identification of Tyr74 and Tyr177 as substrate oxidation sites in cationic cell wall-bound peroxidase from Populus alba L.
PubMed:
A unique two-way approach for the validation of total antioxidant capacity of serum samples.
PubMed:
Bacillus pumilus laccase: a heat stable enzyme with a wide substrate spectrum.
PubMed:
Evaluation of toxicity and degradation of a chlorophenol mixture by the laccase produced by Trametes pubescens.
PubMed:
A bacterial laccase from marine microbial metagenome exhibiting chloride tolerance and dye decolorization ability.
PubMed:
Poly-o-aminophenol as a laccase mediator and influence of the enzyme on the polymer electrodeposition.
PubMed:
First description of a laccase-like enzyme in soil algae.
PubMed:
Enhanced expression of a recombinant bacterial laccase at low temperature and microaerobic conditions: purification and biochemical characterization.
PubMed:
Molecular cloning and characterization of a novel metagenome-derived multicopper oxidase with alkaline laccase activity and highly soluble expression.
PubMed:
Scanning electrochemical microscopy activity mapping of electrodes modified with laccase encapsulated in sol-gel processed matrix.
PubMed:
LccA, an archaeal laccase secreted as a highly stable glycoprotein into the extracellular medium by Haloferax volcanii.
PubMed:
Purification and characteristics of an enzyme with both bilirubin oxidase and laccase activities from mycelium of the basidiomycete Pleurotus ostreatus.
PubMed:
Plasticity of laccase generated by homeologous recombination in yeast.
PubMed:
Purification and characterization of extracellular laccase secreted by Pleurotus sajor-caju MTCC 141.
PubMed:
Selection of Trichoderma strains capable of increasing laccase production by Pleurotus ostreatus and Agaricus bisporus in dual cultures.
PubMed:
Antioxidant activity assay based on laccase-generated radicals.
PubMed:
A new Stenotrophomonas maltophilia strain producing laccase. Use in decolorization of synthetics dyes.
PubMed:
Automated colorimetric determination of recombinant fungal laccase activity in fermentation sarples using syringaldazine as chromogenic substrate.
PubMed:
Production of two novel laccase isoforms by a thermotolerant strain of Pycnoporus sanguineus isolated from an oil-polluted tropical habitat.
PubMed:
Gene cloning, protein purification, and enzymatic properties of multicopper oxidase, from Klebsiella sp. 601.
PubMed:
Purification and characterization of laccase secreted by L. lividus.
PubMed:
Purification, characterization, and identification of a novel bifunctional catalase-phenol oxidase from Scytalidium thermophilum.
PubMed:
Cloning and characterization of a new laccase from Bacillus licheniformis catalyzing dimerization of phenolic acids.
PubMed:
Enzymatic nanoreactors for environmentally benign biotransformations. 1. Formation and catalytic activity of supramolecular complexes of laccase and linear-dendritic block copolymers.
PubMed:
The influence of ortho- and para-diphenoloxidase substrates on pigment formation in black yeast-like fungi.
PubMed:
An alkali-stable enzyme with laccase activity from entophytic fungus and the enzymatic modification of alkali lignin.
PubMed:
Purification and biochemical characterization of a laccase from the aquatic fungus Myrioconium sp. UHH 1-13-18-4 and molecular analysis of the laccase-encoding gene.
PubMed:
Role of Tyr residues on the protein surface of cationic cell-wall-peroxidase (CWPO-C) from poplar: potential oxidation sites for oxidative polymerization of lignin.
PubMed:
Effects of pollutants on laccase activities of Marasmius quercophilus, a white-rot fungus isolated from a Mediterranean schlerophyllous litter.
PubMed:
Novel thermotolerant laccases produced by the white-rot fungus Physisporinus rivulosus.
PubMed:
A robust metallo-oxidase from the hyperthermophilic bacterium Aquifex aeolicus.
PubMed:
Implication of mycelium-associated laccase from Irpex lacteus in the decolorization of synthetic dyes.
PubMed:
Dual fluorescence of syringaldazine.
PubMed:
Peroxidases and lignification in relation to the intensity of water-deficit stress in white clover (Trifolium repens L.).
PubMed:
Studies on the Pycnoporus sanguineus CCT-4518 laccase purified by hydrophobic interaction chromatography.
PubMed:
Purification and characterization of laccase from Pycnoporus sanguineus and decolorization of an anthraquinone dye by the enzyme.
PubMed:
High production of laccase by a new basidiomycete, Trametes sp.
PubMed:
[Increase of the detoxification potential of basidiomycetes by induction of laccase biosynthesis].
PubMed:
The effect of a catecholate chelator as a redox agent in Fenton-based reactions on degradation of lignin-model substrates and on COD removal from effluent of an ECF kraft pulp mill.
PubMed:
Purification and characteristics of a low-molecular-weight peptide possessing oxidative capacity for phenol from Phanerochaete chrysosporium.
PubMed:
Resonance Raman evidence of immobilization of laccase on self-assembled monolayers of thiols on Ag and Au surfaces.
PubMed:
Occurrence of laccases in lichenized ascomycetes of the Peltigerineae.
PubMed:
Thiobarbituric acid reactive substances, Fe3+ reduction and enzymatic activities in cultures of Ganoderma australe growing on Drimys winteri wood.
PubMed:
Novel polyphenol oxidase mined from a metagenome expression library of bovine rumen: biochemical properties, structural analysis, and phylogenetic relationships.
PubMed:
Properties of laccases produced by Pycnoporus sanguineus induced by 2,5-xylidine.
PubMed:
Purification and characterization of laccase produced by a white rot fungus Pleurotus sajor-caju under submerged culture condition and its potential in decolorization of azo dyes.
PubMed:
[Yellow laccase from the fungus Pleurotus ostreatus D1: purification and characterization].
PubMed:
Coupling of 2,4,6-trinitrotoluene (TNT) metabolites onto humic monomers by a new laccase from Trametes modesta.
PubMed:
Monolignol oxidation by xylem peroxidase isoforms of Norway spruce (Picea abies) and silver birch (Betula pendula).
PubMed:
Production, properties and application to biocatalysis of a novel extracellular alkaline phenol oxidase from the thermophilic fungus Scytalidium thermophilum.
PubMed:
The possible involvement of peroxidase in defense of yellow lupine embryo axes against Fusarium oxysporum.
PubMed:
Laccase and Mn-peroxidase production by Coriolus hirsutus strain 075 in a jar fermentor.
PubMed:
Laccase-type phenoloxidase in salivary glands and watery saliva of the green rice leafhopper, Nephotettix cincticeps.
PubMed:
Ionic liquid-reconstituted cellulose composites as solid support matrices for biocatalyst immobilization.
PubMed:
Extracellular oxidases of the lignin-degrading fungus Panus tigrinus.
PubMed:
A hyperthermophilic laccase from Thermus thermophilus HB27.
PubMed:
Inhibition of laccase activity from Trametes versicolor by heavy metals and organic compounds.
PubMed:
The white-rot fungus Cerrena unicolor strain 137 produces two laccase isoforms with different physico-chemical and catalytic properties.
PubMed:
A note concerning acetate activation of peroxidative activity of catalases using 2,2'-azino-bis(3-ethylbenzthiazoline)-6-sulfonic acid as a substrate.
PubMed:
Induction of oxidative stress and antioxidative mechanisms in Phaseolus vulgaris after Cd application.
PubMed:
Laccase from the medicinal mushroom Agaricus blazei: production, purification and characterization.
PubMed:
Structural close-related aromatic compounds have different effects on laccase activity and on lcc gene expression in the ligninolytic fungus Trametes sp. I-62.
PubMed:
A high sensitivity amperometric biosensor using a monomolecular layer of laccase as biorecognition element.
PubMed:
A cloned Bacillus halodurans multicopper oxidase exhibiting alkaline laccase activity.
PubMed:
Selective induction, purification and characterization of a laccase isozyme from the basidiomycete Trametes sp. AH28-2.
PubMed:
A thermostable laccase from Streptomyces lavendulae REN-7: purification, characterization, nucleotide sequence, and expression.
PubMed:
Purification and characterization of laccase from the rice blast fungus, Magnaporthe grisea.
PubMed:
Changes in antioxidant and lignifying enzyme activities in sunflower roots (Helianthus annuus L.) stressed with copper excess.
PubMed:
Purification and characterization of laccase from the white-rot fungus Daedalea quercina and decolorization of synthetic dyes by the enzyme.
PubMed:
Electrochemical characterization of purified Rhus vernicifera laccase: voltammetric evidence for a sequential four-electron transfer.
PubMed:
Purification and characterization of the main laccase produced by the white-rot fungus Pleurotus pulmonarius on wheat bran solid state medium.
PubMed:
Enzymological characterization of EpoA, a laccase-like phenol oxidase produced by Streptomyces griseus.
PubMed:
Purification and characterization of a peroxidase from corn steep water.
PubMed:
Functional expression of a fungal laccase in Saccharomyces cerevisiae by directed evolution.
PubMed:
[Producing characterization of constitutive-form laccase by Basidiomycete].
PubMed:
Molecular cloning of a laccase isozyme gene from Pleurotus sajor-caju and expression in the heterologous Pichia pastoris host.
PubMed:
Characterization of a low redox potential laccase from the basidiomycete C30.
PubMed:
Enhanced activity by poly(ethylene glycol) modification of Coriolopsis gallica laccase.
PubMed:
Purification of a new isoform of laccase from a Marasmius quercophilus strain isolated from a cork oak litter (Quercus suber L).
PubMed:
Purification and characterisation of a novel laccase from the ascomycete Melanocarpus albomyces.
PubMed:
Characterization of the major laccase isoenzyme from Trametes pubescens and regulation of its synthesis by metal ions.
PubMed:
Effects of Pb-EDTA and EDTA on oxidative stress reactions and mineral uptake in Phaseolus vulgaris.
PubMed:
Laccase activity in melanin-producing strains of Sinorhizobium meliloti.
PubMed:
Molecular and biochemical characterization of a highly stable bacterial laccase that occurs as a structural component of the Bacillus subtilis endospore coat.
PubMed:
The syringaldazine-oxidizing peroxidase PXP 3-4 from poplar xylem: cDNA isolation, characterization and expression.
PubMed:
CotA of Bacillus subtilis is a copper-dependent laccase.
PubMed:
Characterization of a novel laccase produced by the wood-rotting fungus Phellinus ribis.
PubMed:
Response to mild water stress in transgenic Pssu-ipt tobacco.
PubMed:
Cloning of a phenol oxidase gene from Acremonium murorum and its expression in Aspergillus awamori.
PubMed:
Kinetic differences of purified laccases from six Pleurotus ostreatus strains.
PubMed:
Iron deficiency differently affects peroxidase isoforms in sunflower.
PubMed:
Redox state and peroxidase system in sunflower plants exposed to ozone.
PubMed:
Characterization and immobilization of the laccase from Pleurotus ostreatus and its use for the continuous elimination of phenolic pollutants.
PubMed:
[Certain biochemical and physicochemical properties of the inducible form of extracellular laccase from basidiomycetes Coriolus hirsutus].
PubMed:
Effect of ethanol on enzymatic activity of fungal laccases.
PubMed:
Phenol-oxidase (laccase) activity in strains of the hyphomycete Chalara paradoxa isolated from olive mill wastewater disposal ponds.
PubMed:
A tomato peroxidase involved in the synthesis of lignin and suberin.
PubMed:
Biochemical and molecular characterization of a laccase from Marasmius quercophilus.
PubMed:
Extracellular oxidases from solid-state culture of the ligninolytic fungus panus tigrinus 8/18
PubMed:
Phytohormone regulation of isoperoxidases in Catharanthus roseus suspension cultures.
PubMed:
Purification and characterization of peroxidases correlated with lignification in poplar xylem.
PubMed:
Purification and characterization of laccase from Chaetomium thermophilium and its role in humification.
PubMed:
Purification and characterization of the constitutive form of laccase from the basidiomycete Coriolus hirsutus and effect of inducers on laccase synthesis.
PubMed:
Laccase--and not tyrosinase--is the enzyme responsible for quinone methide production from 2,6-dimethoxy-4-allyl phenol.
PubMed:
A novel white laccase from Pleurotus ostreatus.
PubMed:
A pluripotent polyphenol oxidase from the melanogenic marine Alteromonas sp shares catalytic capabilities of tyrosinases and laccases.
PubMed:
Electrophoretic separation and identification of phenoloxidases in hemolymph and midgut of adult Anopheles stephensi mosquitoes.
PubMed:
Characterization of the gene encoding an extracellular laccase of Myceliophthora thermophila and analysis of the recombinant enzyme expressed in Aspergillus oryzae.
PubMed:
Syringaldazine. New attractive electron donor of prostaglandin H synthase.
PubMed:
Tissue printing for peroxidases associated with lignification.
PubMed:
Development of a gas-phase oxygen biosensor using a blue copper-containing oxidase.
PubMed:
Purification, characterization, molecular cloning, and expression of two laccase genes from the white rot basidiomycete Trametes villosa.
PubMed:
The identification and characterization of four laccases from the plant pathogenic fungus Rhizoctonia solani.
PubMed:
A study of a series of recombinant fungal laccases and bilirubin oxidase that exhibit significant differences in redox potential, substrate specificity, and stability.
PubMed:
Effects of manganese deficiency on soluble apoplastic peroxidase activities and lignin content in needles of Norway spruce (Picea abies).
PubMed:
Oxidase of the white rot fungus Panus tigrinus 8/18.
PubMed:
Participation of Mn(II) in the catalysis of laccase, manganese peroxidase and lignin peroxidase from Phelbia radiata.
PubMed:
Characterization of Anionic Peroxidases in Tomato Isolines Infected by Meloidogyne incognita.
PubMed:
Studies on the enzymes involved in puparial cuticle sclerotization in Drosophila melanogaster.
PubMed:
The effect of water content and nature of organic solvent on enzyme activity in low-water media. A quantitative description.
PubMed:
Induction of Isoperoxidases in Resistant and Susceptible Tomato Cultivars by Meloidogyne incognita.
PubMed:
On the latency and nature of phenoloxidase present in the left colleterial gland of the cockroach Periplaneta americana.
PubMed:
Changes in peroxidase activity in cell structures of lupin roots infected by Fusarium culmorum.
PubMed:
Measurement of oxygen solubility in fermentation media: a colorimetric method.
PubMed:
Delignification of Wood Chips and Pulps by Using Natural and Synthetic Porphyrins: Models of Fungal Decay.
PubMed:
Solubilization of Leonardite by an Extracellular Fraction from Coriolus versicolor.
PubMed:
Isolation and characterization of Populus isoperoxidases involved in the last step of lignin formation.
PubMed:
Properties of syringaldazine oxidase/peroxidase in maize roots.
PubMed:
Analysis, Production, and Isolation of an Extracellular Laccase from Polyporus anceps.
PubMed:
Use of syringaldazine for detection of laccase in sporophores of wood rotting fungi.
PubMed:
Lignification in trees: indication of exclusive peroxidase participation.
PubMed:
Bacteriological evaluation of two test methods for chlorine in swimming pools.