thiram
disulfide, bis(dimethylthiocarbamoyl)
Identification
| Name | thiram |
| IUPAC | dimethylcarbamothioylsulfanyl N,N-dimethylcarbamodithioate |
| CAS Number | 137-26-8 |
| EINECS | 205-286-2 |
| FDA UNII | 0D771IS0FH |
| Molecular Formula | C6 H12 N2 S4 |
| Molecular Weight | 240.43564000 |
| MDL Number | MFCD00008325 |
| Nikkaji Number | J2.949A |
| Beilstein | 1725821 |
Regulatory
| FDA Mainterm (IAUFC) | 137-26-8 ; THIRAM |
Physical Properties
| Appearance | white crystalline solid (est) |
| Assay | 95.00 to 100.00 |
| Food Chemicals Codex Listed | No |
| Melting Point | 155.60 °C. @ 760.00 mm Hg |
| Boiling Point | 307.40 °C. @ 760.00 mm Hg (est) |
| Vapor Pressure | 1.720000 mmHg @ 25.00 °C. (est) |
| Flash Point | 283.00 °F. TCC ( 139.70 °C. ) (est) |
| logP (o/w) | 1.730 |
| Soluble in | water, 30 mg/L @ 25 °C (exp) |
No sensory data available
Safety Information
| Preferred SDS | View |
| Oral/Parenteral Toxicity | oral-bird - wild LD50 300 mg/kg |
| Dermal Toxicity | subcutaneous-mouse LD50 1109 mg/kg |
| Inhalation Toxicity | inhalation-human TCLo 30 ug/m3/5Y-I |
GHS Classification
['GHS Classification in accordance with 29 CFR 1910 (OSHA HCS)', 'GHS Label elements, including precautionary statements']
Safety in Use
| Category | herbicides / pesticides |
| Recommendation for thiram usage levels up to | not for fragrance use. |
| Recommendation for thiram flavor usage levels up to | not for flavor use. |
No supplier data available
Potential Uses
Natural Occurrence
Synonyms
aapirol
aatiram
accel TMT
accelerator T
accelerator thiuram
aceto TETD
arasan 42-S
arasan 70
arasan 75
arasan-M
arasan-SF
arasan-SF-X
chipco thiram 75
cunitex
cyuram DS
delsan
bis(
dimethyl thiocarbamoyl)disulfide
bis(
dimethyl-thiocarbamoyl)-disulfid
bis((
dimethylamino)carbonothioyl) disulfide
bis((
dimethylamino)carbonothioyl) disulphide
dimethylcarbamothioylsulfanyl N,N-dimethylcarbamodithioate
bis(
dimethylthiocarbamoyl) disulfide
bis(
dimethylthiocarbamoyl) disulphide
bis(
dimethylthiocarbamyl) disulfide
disulfide, bis(dimethylthiocarbamoyl)
alpha,alpha'-
dithiobis(dimethylthio)formamide
N,N'-(
dithiodicarbonothioyl)bis(N-methylmethanamine)
ekagom TB
falitiram
fermide
fermide 850
fernacol
fernasan
fernasan A
formalsol
formamide, 1,1'-dithiobis(N,N-dimethylthio-
hermal
hermat TMT
hexathir
kregasan
methyl thiuramdisulfide
methylthiuram disulfide
metiur
metiurac
micropearls
nobecutan
nocceler TT
normersan
orac TMTD
panoram 75
pol-thiuram
pomarsol
radothiram
rezifilm
royal TMTD
sadoplon
sadoplon 75
spotrete
spotrete-F
tersan 75
tersantetramethyldiurane sulfide
tetramethyl thiuram disulfide
tetramethyl thiuramdisulfide
tetramethyl thiurane disulphide
tetramethyldiurane sulphite
tetramethylenethiuram disulfide
tetramethylenethiuram disulphide
tetramethylthiocarbamoyldisulphide
tetramethylthioperoxydicarbonic diamide
tetramethylthioramdisulfide
tetramethylthiuram bisulfide
tetramethylthiuram bisulphide
tetramethylthiuram disulfide
N,N-
tetramethylthiuram disulfide
N,N,N',N'-
tetramethylthiuram disulfide
tetramethylthiuram disulphide
N,N-
tetramethylthiuram disulphide
tetramethylthiuran disulphide
tetramethylthiurane disulfide
tetramethylthiurum disulfide
tetramethylthiurum disulphide
tetrapom
tetrasipton
tetrathiuram disulfide
tetrathiuram disulphide
thianosan
thioperoxydicarbonic diamide (((H2N)C(S))2S2), N,N,N',N'-tetramethyl-
thioperoxydicarbonic diamide (((H2N)C(S))2S2), tetramethyl-
thioperoxydicarbonic diamide, tetramethyl-
thioscabin
thiotox (fungicide)
thiram 75
thiram 80
thiram B
thiramad
thiulix
TMTDS
PubMed:
Development of gold nanoparticles modified screen-printed carbon electrode for the analysis of thiram, disulfiram and their derivative in food using ultra-high performance liquid chromatography.
PubMed:
Rapid simultaneous detection of multi-pesticide residues on apple using SERS technique.
PubMed:
Experimental approaches to test pesticide-treated seed avoidance by birds under a simulated diversification of food sources.
PubMed:
Production of apple-based baby food: changes in pesticide residues.
PubMed:
Isotopic niche metrics as indicators of toxic stress in two freshwater snails.
PubMed:
Selective determination of thiram residues in fruit and vegetables by hydrophilic interaction LC-MS.
PubMed:
Method validation and analysis of nine dithiocarbamates in fruits and vegetables by LC-MS/MS.
PubMed:
Graphene oxide embedded sandwich nanostructures for enhanced Raman readout and their applications in pesticide monitoring.
PubMed:
Experimental exposure of red-legged partridges (Alectoris rufa) to seeds coated with imidacloprid, thiram and difenoconazole.
PubMed:
Optofluidic surface enhanced Raman spectroscopy microsystem for sensitive and repeatable on-site detection of chemical contaminants.
PubMed:
The role of matrix gla protein in ossification and recovery of the avian growth plate.
PubMed:
Chromosomal aberrations in cultured human lymphocytes treated with the fungicide, Thiram.
PubMed:
Direct analysis of dithiocarbamate fungicides in fruit by ambient mass spectrometry.
PubMed:
[Determination of 4 dithiocarbamate residues in 22 matrices by gas chromatography].
PubMed:
Pesticide residues intake of French adults under increased consumption of fresh fruits and vegetables--a theoretical study.
PubMed:
Comparison of neem or oregano with thiram on organic matter decomposition of a sand loam soil amended with compost, and on soil biological activity.
PubMed:
Contact allergy to thiurams: multifactorial analysis of clinical surveillance data collected by the IVDK network.
PubMed:
Deer responses to repellent stimuli.
PubMed:
Mechanism of potentiation of endosulfan cytotoxicity by thiram in Ehrlich ascites tumor cells.
PubMed:
Expression of matrix metalloproteinases during impairment and recovery of the avian growth plate.
PubMed:
Adsorption-desorption behavior of thiram onto humic acid.
PubMed:
Quantification of Fusarium graminearum in harvested grain by real-time polymerase chain reaction to assess efficacies of fungicides on fusarium head blight, deoxynivalenol contamination, and yield of winter wheat.
PubMed:
Influence of fulvic acids and copper ions on thiram determination in water.
PubMed:
Screening preharvest/postharvest strategies to prevent fruit rot decay.
PubMed:
Corticosterone oxidative neutralization by 11-beta hydroxysteroid dehydrogenases in kidney and colon of the domestic fowl.
PubMed:
Induction of tibial dyschondroplasia in turkeys by tetramethylthiuram disulfide (thiram).
PubMed:
A solid-phase extraction procedure for the clean-up of thiram from aqueous solutions containing high concentrations of humic substances.
PubMed:
Safe apples for baby-food production: survey of pesticide treatment regimes leaving minimum residues.
PubMed:
Differential regulation of MMPs and matrix assembly in chicken and turkey growth-plate chondrocytes.
PubMed:
Thiram: degradation, applications and analytical methods.
PubMed:
Decreasing allergic contact dermatitis frequency through dermatotoxicologic and epidemiologic based intervention?
PubMed:
Microwave-assisted extraction (MAE)-acid hydrolysis of dithiocarbamates for trace analysis in tobacco and peaches.
PubMed:
Spontaneous formation of thiuram disulfides in solutions of iron(III) dithiocarbamates.
PubMed:
Determination of dithiocarbamate fungicide residues in food by a spectrophotometric method using a vertical disulfide reaction system.
PubMed:
Development of an immunoassay (ELISA) for the quantification of thiram in lettuce.
PubMed:
Reasons for the decomposition of the fungicide thiram during preparation of fruit and vegetable samples and consequences for residue analysis.
PubMed:
Hapten synthesis for the development of a competitive inhibition enzyme-immunoassay for thiram.
PubMed:
Major degradation pathway of thiuram in tap water processed by oxidation with sodium hypochlorite.
PubMed:
A new low-cost microbiotest with the Protozoan spirostomum teres: culture conditions and assessment of sensitivity of the ciliate to 14 pure chemicals.
PubMed:
Analysis of micronuclei and DNA single-strand breaks in mouse splenocytes and peripheral lymphocytes after oral administration of tetramethylthiuram disulfide (thiram).
PubMed:
Assessment of mutagenic potential of thiram.
PubMed:
Xenobiotics and food allergy: in vivo and in vitro studies in patients with apple allergy.
PubMed:
An outbreak of thiram poisoning on Spanish poultry farms.
PubMed:
Carcinogenic and co-carcinogenic studies of thiram on mouse skin.
PubMed:
Induction of tibial dyschondroplasia and suppression of cell-mediated immunity in chickens by Fusarium oxysporum grown on sterile corn.
PubMed:
Genotoxicity of dithiocarbamates and their metabolites.
PubMed:
Chronic toxicity studies with thiram in Wistar rats and beagle dogs.
PubMed:
The effect of thiram on the germ cells of male mice.
PubMed:
[Determination of the vulcanization accelerator thiuram D and its conversion products in sanitary chemical research on rubbers].
PubMed:
High-performance liquid chromatographic determination of dimethyldithiocarbamate residues in some agricultural products.
PubMed:
An example of interaction between environmental pollutants: modification of thiram toxicity to freshwater organisms by nitrites or nitrates in relation to nitrosamine synthesis.
PubMed:
Mutagenic effects of thiram in mammalian somatic cells.
PubMed:
[Determination of ethylenebis(dithiocarbamate) fungicides and thiram in the plants].
PubMed:
Inhibition of spontaneous leukemia in F-344 rats by tetramethylthiuram disulfide (thiram).
PubMed:
[Determination of thiuram EF in biomedia by thin-layer chromatography].
PubMed:
Dietary no-effect level of a dithiocarbamate fungicide, thiram, evaluated from measurement data on rats. I. Choice of the model of the dose-response relationship.
PubMed:
[Toxicity of rubbers intended for food use prepared with the use of thiuram and its derivatives].
PubMed:
Oral toxicity of ferric dimethyl-dithiocarbamate (ferbam) and tetramethylthiuram disulfide (thiram) in rodents.
PubMed:
Formation of dimethylnitrosamine from pesticides carrying methylated tertiary aminogroups in the presence of nitrite at pH 3.
PubMed:
[Approaches to the hygienic evaluation of resins containing tetramethylthiuram disulfide and intended for contact with food products].
PubMed:
[Short term effects of diets with high levels of dithiocarbamates on carbohydrate and lipid metabolism of rat liver].
PubMed:
[Energy metabolism in the liver of rats fed a diet contaminated with dithiocarbamates].
PubMed:
[Persistence of thiuram in green vegetables].
PubMed:
[Hygienic studies of resins intended for contact with food products].
PubMed:
Collaborative study of the determination of the dithiocarbamate residues by a modified carbon disulfide evolution method.