disulfide, bis(dimethylthiocarbamoyl)

CAS: 137-26-8 C6 H12 N2 S4 MW: 240.43564000

Identification

Namethiram
IUPACdimethylcarbamothioylsulfanyl N,N-dimethylcarbamodithioate
CAS Number137-26-8
EINECS205-286-2
FDA UNII0D771IS0FH
Molecular FormulaC6 H12 N2 S4
Molecular Weight240.43564000
MDL NumberMFCD00008325
Nikkaji NumberJ2.949A
Beilstein1725821

Regulatory

FDA Mainterm (IAUFC)137-26-8 ; THIRAM

Physical Properties

Appearance white crystalline solid (est)
Assay 95.00 to 100.00
Food Chemicals Codex Listed No
Melting Point 155.60 °C. @ 760.00 mm Hg
Boiling Point 307.40 °C. @ 760.00 mm Hg (est)
Vapor Pressure 1.720000 mmHg @ 25.00 °C. (est)
Flash Point 283.00 °F. TCC ( 139.70 °C. ) (est)
logP (o/w) 1.730
Soluble in water, 30 mg/L @ 25 °C (exp)

No sensory data available

Safety Information

Preferred SDSView
Oral/Parenteral Toxicityoral-bird - wild LD50 300 mg/kg
Dermal Toxicitysubcutaneous-mouse LD50 1109 mg/kg
Inhalation Toxicityinhalation-human TCLo 30 ug/m3/5Y-I

GHS Classification

['GHS Classification in accordance with 29 CFR 1910 (OSHA HCS)', 'GHS Label elements, including precautionary statements']

Safety in Use

Categoryherbicides / pesticides
Recommendation for thiram usage levels up tonot for fragrance use.
Recommendation for thiram flavor usage levels up tonot for flavor use.

No supplier data available

Potential Uses

None Found

Natural Occurrence

not found in nature

Synonyms

aapirol aatiram accel TMT accelerator T accelerator thiuram aceto TETD arasan 42-S arasan 70 arasan 75 arasan-M arasan-SF arasan-SF-X chipco thiram 75 cunitex cyuram DS delsan bis( dimethyl thiocarbamoyl)disulfide bis( dimethyl-thiocarbamoyl)-disulfid bis(( dimethylamino)carbonothioyl) disulfide bis(( dimethylamino)carbonothioyl) disulphide dimethylcarbamothioylsulfanyl N,N-dimethylcarbamodithioate bis( dimethylthiocarbamoyl) disulfide bis( dimethylthiocarbamoyl) disulphide bis( dimethylthiocarbamyl) disulfide disulfide, bis(dimethylthiocarbamoyl) alpha,alpha'- dithiobis(dimethylthio)formamide N,N'-( dithiodicarbonothioyl)bis(N-methylmethanamine) ekagom TB falitiram fermide fermide 850 fernacol fernasan fernasan A formalsol formamide, 1,1'-dithiobis(N,N-dimethylthio- hermal hermat TMT hexathir kregasan methyl thiuramdisulfide methylthiuram disulfide metiur metiurac micropearls nobecutan nocceler TT normersan orac TMTD panoram 75 pol-thiuram pomarsol radothiram rezifilm royal TMTD sadoplon sadoplon 75 spotrete spotrete-F tersan 75 tersantetramethyldiurane sulfide tetramethyl thiuram disulfide tetramethyl thiuramdisulfide tetramethyl thiurane disulphide tetramethyldiurane sulphite tetramethylenethiuram disulfide tetramethylenethiuram disulphide tetramethylthiocarbamoyldisulphide tetramethylthioperoxydicarbonic diamide tetramethylthioramdisulfide tetramethylthiuram bisulfide tetramethylthiuram bisulphide tetramethylthiuram disulfide N,N- tetramethylthiuram disulfide N,N,N',N'- tetramethylthiuram disulfide tetramethylthiuram disulphide N,N- tetramethylthiuram disulphide tetramethylthiuran disulphide tetramethylthiurane disulfide tetramethylthiurum disulfide tetramethylthiurum disulphide tetrapom tetrasipton tetrathiuram disulfide tetrathiuram disulphide thianosan thioperoxydicarbonic diamide (((H2N)C(S))2S2), N,N,N',N'-tetramethyl- thioperoxydicarbonic diamide (((H2N)C(S))2S2), tetramethyl- thioperoxydicarbonic diamide, tetramethyl- thioscabin thiotox (fungicide) thiram 75 thiram 80 thiram B thiramad thiulix TMTDS PubMed: Development of gold nanoparticles modified screen-printed carbon electrode for the analysis of thiram, disulfiram and their derivative in food using ultra-high performance liquid chromatography. PubMed: Rapid simultaneous detection of multi-pesticide residues on apple using SERS technique. PubMed: Experimental approaches to test pesticide-treated seed avoidance by birds under a simulated diversification of food sources. PubMed: Production of apple-based baby food: changes in pesticide residues. PubMed: Isotopic niche metrics as indicators of toxic stress in two freshwater snails. PubMed: Selective determination of thiram residues in fruit and vegetables by hydrophilic interaction LC-MS. PubMed: Method validation and analysis of nine dithiocarbamates in fruits and vegetables by LC-MS/MS. PubMed: Graphene oxide embedded sandwich nanostructures for enhanced Raman readout and their applications in pesticide monitoring. PubMed: Experimental exposure of red-legged partridges (Alectoris rufa) to seeds coated with imidacloprid, thiram and difenoconazole. PubMed: Optofluidic surface enhanced Raman spectroscopy microsystem for sensitive and repeatable on-site detection of chemical contaminants. PubMed: The role of matrix gla protein in ossification and recovery of the avian growth plate. PubMed: Chromosomal aberrations in cultured human lymphocytes treated with the fungicide, Thiram. PubMed: Direct analysis of dithiocarbamate fungicides in fruit by ambient mass spectrometry. PubMed: [Determination of 4 dithiocarbamate residues in 22 matrices by gas chromatography]. PubMed: Pesticide residues intake of French adults under increased consumption of fresh fruits and vegetables--a theoretical study. PubMed: Comparison of neem or oregano with thiram on organic matter decomposition of a sand loam soil amended with compost, and on soil biological activity. PubMed: Contact allergy to thiurams: multifactorial analysis of clinical surveillance data collected by the IVDK network. PubMed: Deer responses to repellent stimuli. PubMed: Mechanism of potentiation of endosulfan cytotoxicity by thiram in Ehrlich ascites tumor cells. PubMed: Expression of matrix metalloproteinases during impairment and recovery of the avian growth plate. PubMed: Adsorption-desorption behavior of thiram onto humic acid. PubMed: Quantification of Fusarium graminearum in harvested grain by real-time polymerase chain reaction to assess efficacies of fungicides on fusarium head blight, deoxynivalenol contamination, and yield of winter wheat. PubMed: Influence of fulvic acids and copper ions on thiram determination in water. PubMed: Screening preharvest/postharvest strategies to prevent fruit rot decay. PubMed: Corticosterone oxidative neutralization by 11-beta hydroxysteroid dehydrogenases in kidney and colon of the domestic fowl. PubMed: Induction of tibial dyschondroplasia in turkeys by tetramethylthiuram disulfide (thiram). PubMed: A solid-phase extraction procedure for the clean-up of thiram from aqueous solutions containing high concentrations of humic substances. PubMed: Safe apples for baby-food production: survey of pesticide treatment regimes leaving minimum residues. PubMed: Differential regulation of MMPs and matrix assembly in chicken and turkey growth-plate chondrocytes. PubMed: Thiram: degradation, applications and analytical methods. PubMed: Decreasing allergic contact dermatitis frequency through dermatotoxicologic and epidemiologic based intervention? PubMed: Microwave-assisted extraction (MAE)-acid hydrolysis of dithiocarbamates for trace analysis in tobacco and peaches. PubMed: Spontaneous formation of thiuram disulfides in solutions of iron(III) dithiocarbamates. PubMed: Determination of dithiocarbamate fungicide residues in food by a spectrophotometric method using a vertical disulfide reaction system. PubMed: Development of an immunoassay (ELISA) for the quantification of thiram in lettuce. PubMed: Reasons for the decomposition of the fungicide thiram during preparation of fruit and vegetable samples and consequences for residue analysis. PubMed: Hapten synthesis for the development of a competitive inhibition enzyme-immunoassay for thiram. PubMed: Major degradation pathway of thiuram in tap water processed by oxidation with sodium hypochlorite. PubMed: A new low-cost microbiotest with the Protozoan spirostomum teres: culture conditions and assessment of sensitivity of the ciliate to 14 pure chemicals. PubMed: Analysis of micronuclei and DNA single-strand breaks in mouse splenocytes and peripheral lymphocytes after oral administration of tetramethylthiuram disulfide (thiram). PubMed: Assessment of mutagenic potential of thiram. PubMed: Xenobiotics and food allergy: in vivo and in vitro studies in patients with apple allergy. PubMed: An outbreak of thiram poisoning on Spanish poultry farms. PubMed: Carcinogenic and co-carcinogenic studies of thiram on mouse skin. PubMed: Induction of tibial dyschondroplasia and suppression of cell-mediated immunity in chickens by Fusarium oxysporum grown on sterile corn. PubMed: Genotoxicity of dithiocarbamates and their metabolites. PubMed: Chronic toxicity studies with thiram in Wistar rats and beagle dogs. PubMed: The effect of thiram on the germ cells of male mice. PubMed: [Determination of the vulcanization accelerator thiuram D and its conversion products in sanitary chemical research on rubbers]. PubMed: High-performance liquid chromatographic determination of dimethyldithiocarbamate residues in some agricultural products. PubMed: An example of interaction between environmental pollutants: modification of thiram toxicity to freshwater organisms by nitrites or nitrates in relation to nitrosamine synthesis. PubMed: Mutagenic effects of thiram in mammalian somatic cells. PubMed: [Determination of ethylenebis(dithiocarbamate) fungicides and thiram in the plants]. PubMed: Inhibition of spontaneous leukemia in F-344 rats by tetramethylthiuram disulfide (thiram). PubMed: [Determination of thiuram EF in biomedia by thin-layer chromatography]. PubMed: Dietary no-effect level of a dithiocarbamate fungicide, thiram, evaluated from measurement data on rats. I. Choice of the model of the dose-response relationship. PubMed: [Toxicity of rubbers intended for food use prepared with the use of thiuram and its derivatives]. PubMed: Oral toxicity of ferric dimethyl-dithiocarbamate (ferbam) and tetramethylthiuram disulfide (thiram) in rodents. PubMed: Formation of dimethylnitrosamine from pesticides carrying methylated tertiary aminogroups in the presence of nitrite at pH 3. PubMed: [Approaches to the hygienic evaluation of resins containing tetramethylthiuram disulfide and intended for contact with food products]. PubMed: [Short term effects of diets with high levels of dithiocarbamates on carbohydrate and lipid metabolism of rat liver]. PubMed: [Energy metabolism in the liver of rats fed a diet contaminated with dithiocarbamates]. PubMed: [Persistence of thiuram in green vegetables]. PubMed: [Hygienic studies of resins intended for contact with food products]. PubMed: Collaborative study of the determination of the dithiocarbamate residues by a modified carbon disulfide evolution method.